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Issues
15 April 2018
ISSN 0022-1767
EISSN 1550-6606
In this Issue
IN THIS ISSUE
LETTERS TO THE EDITOR
Comment on “Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells”
J Immunol (2018) 200 (8): 2515–2516.
BRIEF REVIEWS
The Impact of Maternal Microbes and Microbial Colonization in Early Life on Hematopoiesis
J Immunol (2018) 200 (8): 2519–2526.
CUTTING EDGE
Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice
Sanjeev Kiran Gotru; Jesus Gil-Pulido; Niklas Beyersdorf; Andreas Diefenbach; Isabelle C. Becker; Timo Vögtle; Katharina Remer; Vladimir Chubanov; Thomas Gudermann; Heike M. Hermanns; Bernhard Nieswandt; Thomas Kerkau; Alma Zernecke; Attila Braun
J Immunol (2018) 200 (8): 2529–2534.
AUTOIMMUNITY
Circulating Exosomes with Distinct Properties during Chronic Lung Allograft Rejection
Muthukumar Gunasekaran; Monal Sharma; Ramsey Hachem; Ross Bremner; Michael A. Smith; Thalachallour Mohanakumar
J Immunol (2018) 200 (8): 2535–2541.
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs
Rolf Spirig; Ian K. Campbell; Sandra Koernig; Chao-Guang Chen; Bonnie J. B. Lewis; Rebecca Butcher; Ineke Muir; Shirley Taylor; Jenny Chia; David Leong; Jason Simmonds; Pierre Scotney; Peter Schmidt; Louis Fabri; Andreas Hofmann; Monika Jordi; Martin O. Spycher; Susann Cattepoel; Jennifer Brasseit; Con Panousis; Tony Rowe; Donald R. Branch; Adriana Baz Morelli; Fabian Käsermann; Adrian W. Zuercher
J Immunol (2018) 200 (8): 2542–2553.
CCR7 on CD4+ T Cells Plays a Crucial Role in the Induction of Experimental Autoimmune Encephalomyelitis
Patrick Belikan; Ulrike Bühler; Christina Wolf; Gautam K. Pramanik; René Gollan; Frauke Zipp; Volker Siffrin
J Immunol (2018) 200 (8): 2554–2562.
CLINICAL AND HUMAN IMMUNOLOGY
MTOR Suppresses Cigarette Smoke–Induced Epithelial Cell Death and Airway Inflammation in Chronic Obstructive Pulmonary Disease
Yong Wang; Juan Liu; Jie-Sen Zhou; Hua-Qiong Huang; Zhou-Yang Li; Xu-Chen Xu; Tian-Wen Lai; Yue Hu; Hong-Bin Zhou; Hai-Pin Chen; Song-Min Ying; Wen Li; Hua-Hao Shen; Zhi-Hua Chen
J Immunol (2018) 200 (8): 2571–2580.
Loss of the Immune Checkpoint CD85j/LILRB1 on Malignant Plasma Cells Contributes to Immune Escape in Multiple Myeloma
Ester Lozano; Tania Díaz; Mari-Pau Mena; Guillermo Suñe; Xavier Calvo; Marcos Calderón; Lorena Pérez-Amill; Vanina Rodríguez; Patricia Pérez-Galán; Gaël Roué; M. Teresa Cibeira; Laura Rosiñol; Ignacio Isola; Luis-Gerardo Rodríguez-Lobato; Beatriz Martin-Antonio; Joan Bladé; Carlos Fernández de Larrea
J Immunol (2018) 200 (8): 2581–2591.
IMMUNE REGULATION
Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function
Peter T. Sage; Frank A. Schildberg; Raymond A. Sobel; Vijay K. Kuchroo; Gordon J. Freeman; Arlene H. Sharpe
J Immunol (2018) 200 (8): 2592–2602.
Lnc-chop Promotes Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor and Inflammatory Environments
J Immunol (2018) 200 (8): 2603–2614.
A Restricted Role for FcγR in the Regulation of Adaptive Immunity
Marieke F. Fransen; Hreinn Benonisson; Wendy W. van Maren; Heng Sheng Sow; Cor Breukel; Margot M. Linssen; Jill W. C. Claassens; Conny Brouwers; Jos van der Kaa; Marcel Camps; Jan Willem Kleinovink; Kelly K. Vonk; Sandra van Heiningen; Ngaisah Klar; Lianne van Beek; Vanessa van Harmelen; Lucia Daxinger; Kutty S. Nandakumar; Rikard Holmdahl; Chris Coward; Qingshun Lin; Sachiko Hirose; Daniela Salvatori; Thorbald van Hall; Cees van Kooten; Piero Mastroeni; Ferry Ossendorp; J. Sjef Verbeek
J Immunol (2018) 200 (8): 2615–2626.
B Cell–Intrinsic mTORC1 Promotes Germinal Center–Defining Transcription Factor Gene Expression, Somatic Hypermutation, and Memory B Cell Generation in Humoral Immunity
Ariel L. Raybuck; Sung Hoon Cho; Jingxin Li; Meredith C. Rogers; Keunwook Lee; Christopher L. Williams; Mark Shlomchik; James W. Thomas; Jin Chen; John V. Williams; Mark R. Boothby
J Immunol (2018) 200 (8): 2627–2639.
IMMUNOGENETICS
Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa
Neda Nemat-Gorgani; Hugo G. Hilton; Brenna M. Henn; Meng Lin; Christopher R. Gignoux; Justin W. Myrick; Cedric J. Werely; Julie M. Granka; Marlo Möller; Eileen G. Hoal; Makoto Yawata; Nobuyo Yawata; Lies Boelen; Becca Asquith; Peter Parham; Paul J. Norman
J Immunol (2018) 200 (8): 2640–2655.
IMMUNOTHERAPY AND VACCINES
All-Trans Retinoic Acid Enhances Antibody Production by Inducing the Expression of Thymic Stromal Lymphopoietin Protein
Takahiro Hatayama; Ryosuke Segawa; Natsumi Mizuno; Sumiko Eguchi; Hiroshi Akamatsu; Misaki Fukuda; Fumihisa Nakata; Warren J. Leonard; Masahiro Hiratsuka; Noriyasu Hirasawa
J Immunol (2018) 200 (8): 2670–2676.
INFECTIOUS DISEASE AND HOST RESPONSE
Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells
J Immunol (2018) 200 (8): 2690–2702.
Associations of Simian Immunodeficiency Virus (SIV)-Specific Follicular CD8+ T Cells with Other Follicular T Cells Suggest Complex Contributions to SIV Viremia Control
Mohammad Arif Rahman; Katherine M. McKinnon; Tatiana S. Karpova; David A. Ball; David J. Venzon; Wenjin Fan; Guobin Kang; Qingsheng Li; Marjorie Robert-Guroff
J Immunol (2018) 200 (8): 2714–2726.
INNATE IMMUNITY AND INFLAMMATION
IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production
J Immunol (2018) 200 (8): 2738–2747.
Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling
J Immunol (2018) 200 (8): 2748–2756.
15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia
Ho Pan Sham; Katherine H. Walker; Raja-Elie E. Abdulnour; Nandini Krishnamoorthy; David N. Douda; Paul C. Norris; Ioanna Barkas; Sarah Benito-Figueroa; Jennifer K. Colby; Charles N. Serhan; Bruce D. Levy
J Immunol (2018) 200 (8): 2757–2766.
Teleost Basophils Have IgM-Dependent and Dual Ig-Independent Degranulation Systems
J Immunol (2018) 200 (8): 2767–2776.
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
J Immunol (2018) 200 (8): 2777–2785.
Contribution of Adipose-Derived Factor D/Adipsin to Complement Alternative Pathway Activation: Lessons from Lipodystrophy
Xiaobo Wu; Irina Hutson; Antonina M. Akk; Smita Mascharak; Christine T. N. Pham; Dennis E. Hourcade; Rebecca Brown; John P. Atkinson; Charles A. Harris
J Immunol (2018) 200 (8): 2786–2797.
Intravesicular Acidification Regulates Lipopolysaccharide Inflammation and Tolerance through TLR4 Trafficking
Motoya Murase; Takumi Kawasaki; Rika Hakozaki; Takuya Sueyoshi; Dyaningtyas Dewi Pamungkas Putri; Yuichi Kitai; Shintaro Sato; Masahito Ikawa; Taro Kawai
J Immunol (2018) 200 (8): 2798–2808.
Decay of the Stress-Induced Ligand MICA Is Controlled by the Expression of an Alternative 3′ Untranslated Region
J Immunol (2018) 200 (8): 2819–2825.
MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
Zhouyang Li; Yinfang Wu; Hai-Pin Chen; Chen Zhu; Lingling Dong; Yong Wang; Huiwen Liu; Xuchen Xu; Jiesen Zhou; Yanping Wu; Wen Li; Songmin Ying; Huahao Shen; Zhi-Hua Chen
J Immunol (2018) 200 (8): 2826–2834.
Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome
Haipeng Yin; Qiang Guo; Xin Li; Tiantian Tang; Cuiling Li; Hengxiao Wang; Yuanxin Sun; Qi Feng; Chunhong Ma; Chengjiang Gao; Fan Yi; Jun Peng
J Immunol (2018) 200 (8): 2835–2846.
Identification of MHC Class Ib Ligands for Stimulatory and Inhibitory Ly49 Receptors and Induction of Potent NK Cell Alloresponses in Rats
J Immunol (2018) 200 (8): 2847–2859.
MOLECULAR AND STRUCTURAL IMMUNOLOGY
The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability
Ida Hafstrand; Elien M. Doorduijn; Renhua Sun; Anna Talyzina; Marjolein Sluijter; Sara Pellegrino; Tatyana Sandalova; Adil Doganay Duru; Thorbald van Hall; Adnane Achour
J Immunol (2018) 200 (8): 2860–2868.
Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily
Rong Chen; Lijie Zhang; Jianxun Qi; Nianzhi Zhang; Ling Zhang; Shugang Yao; Yanan Wu; Bo Jiang; Zhenbao Wang; Hongyu Yuan; Qiujin Zhang; Chun Xia
J Immunol (2018) 200 (8): 2869–2881.
Bach2 Promotes B Cell Receptor–Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors
Yuichi Miura; Mizuho Morooka; Nicolas Sax; Rahul Roychoudhuri; Ari Itoh-Nakadai; Andrey Brydun; Ryo Funayama; Keiko Nakayama; Susumu Satomi; Mitsuyo Matsumoto; Kazuhiko Igarashi; Akihiko Muto
J Immunol (2018) 200 (8): 2882–2893.
MUCOSAL IMMUNOLOGY
The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection
Pritesh Desai; Vikas Tahiliani; Tarun E. Hutchinson; Farhad Dastmalchi; Jessica Stanfield; Georges Abboud; Paul G. Thomas; Carl F. Ware; Jianxun Song; Michael Croft; Shahram Salek-Ardakani
J Immunol (2018) 200 (8): 2894–2904.
Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation
Brinda Bhatt; Peng Zeng; Huabin Zhu; Sathish Sivaprakasam; Siyi Li; Haiyan Xiao; Lixin Dong; Pamela Shiao; Ravindra Kolhe; Nikhil Patel; Honglin Li; Daniel Levy-Bercowski; Vadivel Ganapathy; Nagendra Singh
J Immunol (2018) 200 (8): 2905–2914.
CXCL17 Chemokine–Dependent Mobilization of CXCR8+CD8+ Effector Memory and Tissue-Resident Memory T Cells in the Vaginal Mucosa Is Associated with Protection against Genital Herpes
Ruchi Srivastava; Marcela Hernández-Ruiz; Arif A. Khan; Mona A. Fouladi; Grace J. Kim; Vincent T. Ly; Taikun Yamada; Cynthia Lam; Sheilouise A. B. Sarain; Undariya Boldbaatar; Albert Zlotnik; Elmostafa Bahraoui; Lbachir BenMohamed
J Immunol (2018) 200 (8): 2915–2926.
SYSTEMS IMMUNOLOGY
TRANSPLANTATION
TUMOR IMMUNOLOGY
Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner
Yuki Katayama; Masashi Tachibana; Nozomi Kurisu; Yukako Oya; Yuichi Terasawa; Hiroshi Goda; Kouji Kobiyama; Ken J. Ishii; Shizuo Akira; Hiroyuki Mizuguchi; Fuminori Sakurai
J Immunol (2018) 200 (8): 2987–2999.
NOVEL IMMUNOLOGICAL METHODS
Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity
Karen O. Dixon; Michelle Schorer; James Nevin; Yassaman Etminan; Zohreh Amoozgar; Takaaki Kondo; Sema Kurtulus; Nasim Kassam; Raymond A. Sobel; Dai Fukumura; Rakesh K. Jain; Ana C. Anderson; Vijay K. Kuchroo; Nicole Joller
J Immunol (2018) 200 (8): 3000–3007.
A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection
Wendy E. Whatney; Neel R. Gandhi; Cecilia S. Lindestam Arlehamn; Azhar Nizam; Hao Wu; Melanie J. Quezada; Angela Campbell; Salim Allana; Mbuyi Madeleine Kabongo; Jeremiah Khayumbi; Benson Muchiri; Joshua Ongalo; Joan Tonui; Loren E. Sasser; Tawania J. Fergus; Gregory Sadat Ouma; Samuel Gurrion Ouma; Allison A. Beck; Mark J. Mulligan; Alawode Oladele; Deepak Kaushal; Kevin P. Cain; Lance Waller; Henry M. Blumberg; John D. Altman; Joel D. Ernst; Jyothi Rengarajan; Cheryl L. Day; for the TBRU-ASTRa Study Group
J Immunol (2018) 200 (8): 3008–3019.
CORRECTIONS
Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity
Joanne A. O’Donnell; Jesse Lehman; Justine E. Roderick; Dalia Martinez-Marin; Matija Zelic; Ciara Doran; Nicole Hermance; Stephen Lyle; Manolis Pasparakis; Katherine A. Fitzgerald; Ann Marshak-Rothstein; Michelle A. Kelliher
J Immunol (2018) 200 (8): 3020–3021.
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Cover Image
Cover Image
On the cover: An IgVJ-C2 molecule found in invertebrate amphioxus (AmpIgVJ-C2) reveals critical structural features characteristic of vertebrate adaptive immune receptors. Immunogold electron microscopy shows that IgVJ-C2 is localized in secretory granules, cell protrusions, and cilia of intestine, which are considered to be major immune response sites. Chen, R., L. Zhang, J. Qi, N. Zhang, L. Zhang, S. Yao, Y. Wu, B. Jiang, Z. Wang, H. Yuan, Q. Zhang, and C. Xia. 2018. Discovery and analysis of invertebrate IgVJ-C2 structure from amphioxus provides insight into the evolution of the Ig superfamily. J. Immunol. 200: 2869–2881.
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