Skip to Main Content

Advertisement

American Association of Immunologists Journals
header search
Search
Advanced Search
Skip Nav Destination

Issues

Volume 201, Issue 9
1 November 2018
Issue Cover
ISSN 0022-1767
EISSN 1550-6606

IN THIS ISSUE

In This Issue
J Immunol (2018) 201 (9): 2525–2526.
View articletitled, In This Issue
Open the PDF for in another window
Add to Citation Manager

PILLARS OF IMMUNOLOGY

The Common Key to Class-Switch Recombination and Somatic Hypermutation: Discovery of AID and Its Role in Antibody Gene Diversification
Rebecca J. Leeman-Neill; Junghyun Lim; Uttiya Basu
J Immunol (2018) 201 (9): 2527–2529.
View articletitled, The Common Key to Class-Switch Recombination and Somatic Hypermutation: Discovery of AID and Its Role in Antibody Gene Diversification
Open the PDF for in another window
Add to Citation Manager
Pillars Article: Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme. Cell. 2000. 102: 553–563
Masamichi Muramatsu; Kazuo Kinoshita; Sidonia Fagarasan; Shuichi Yamada; Yoichi Shinkai; Tasuku Honjo
J Immunol (2018) 201 (9): 2530–2540.
View articletitled, Pillars Article: Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme. <em>Cell</em>. 2000. 102: 553–563
Open the PDF for in another window
Add to Citation Manager

BRIEF REVIEWS

The End of the Binary Era: Revisiting the Spectrum of Tuberculosis
Philana Ling Lin; JoAnne L. Flynn
J Immunol (2018) 201 (9): 2541–2548.
View articletitled, The End of the Binary Era: Revisiting the Spectrum of Tuberculosis
Open the PDF for in another window
Add to Citation Manager

CUTTING EDGE

Cutting Edge: Local Proliferation of Uterine Tissue-Resident NK Cells during Decidualization in Mice
Dorothy K. Sojka; Liping Yang; Beatrice Plougastel-Douglas; Darryl A. Higuchi; B. Anne Croy; Wayne M. Yokoyama
J Immunol (2018) 201 (9): 2551–2556.
View articletitled, Cutting Edge: Local Proliferation of Uterine Tissue-Resident NK Cells during Decidualization in Mice
Supplementary data
Open the PDF for in another window
Add to Citation Manager

ANTIGEN RECOGNITION AND RESPONSES

A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice
Huiwen Zheng; Jingjing Wang; Bingxiang Li; Lei Guo; Heng Li; Jie Song; Zening Yang; Hongzhe Li; Haitao Fan; Xing Huang; Haiting Long; Chen Cheng; Manman Chu; Zhanlong He; Wenhai Yu; Jiaqi Li; You Gao; Ruotong Ning; Nan Li; Jinxi Yang; Qiongwen Wu; Haijing Shi; Ming Sun; Longding Liu
J Immunol (2018) 201 (9): 2557–2569.
View articletitled, A Novel Neutralizing Antibody Specific to the DE Loop of VP1 Can Inhibit EV-D68 Infection in Mice
Open the PDF for in another window
Add to Citation Manager

AUTOIMMUNITY

WDFY4 Is Involved in Symptoms of Systemic Lupus Erythematosus by Modulating B Cell Fate via Noncanonical Autophagy
Qianqian Yuan; Yan Li; Jiangxia Li; Xianli Bian; Feng Long; Ruonan Duan; Xiaochun Ma; Fei Gao; Shang Gao; Shijun Wei; Xi Li; Wenjie Sun; Qiji Liu
J Immunol (2018) 201 (9): 2570–2578.
View articletitled, WDFY4 Is Involved in Symptoms of Systemic Lupus Erythematosus by Modulating B Cell Fate via Noncanonical Autophagy
Supplementary data
Open the PDF for in another window
Add to Citation Manager
IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells
Natasha C. Ward; Aixin Yu; Alejandro Moro; Yuguang Ban; Xi Chen; Sunnie Hsiung; James Keegan; Jaren M. Arbanas; Martine Loubeau; Anil Thankappan; Aaron P. Yamniuk; Jonathan H. Davis; Mary Struthers; Thomas R. Malek
J Immunol (2018) 201 (9): 2579–2592.
View articletitled, IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells
Supplementary data
Open the PDF for in another window
Add to Citation Manager

CLINICAL AND HUMAN IMMUNOLOGY

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia
Oisín Huhn; Olympe Chazara; Martin A. Ivarsson; Christelle Retière; Timothy C. Venkatesan; Paul J. Norman; Hugo G. Hilton; Jyothi Jayaraman; James A. Traherne; John Trowsdale; Mitsutero Ito; Christiane Kling; Peter Parham; Hormas Ghadially; Ashley Moffett; Andrew M. Sharkey; Francesco Colucci
J Immunol (2018) 201 (9): 2593–2601.
View articletitled, High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia
Supplementary data
Open the PDF for in another window
Add to Citation Manager

IMMUNE REGULATION

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis
Nicole D. Barth; John A. Marwick; Mary Jo Heeb; Andrew J. Gale; Adriano G. Rossi; Ian Dransfield
J Immunol (2018) 201 (9): 2602–2611.
View articletitled, Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis
Supplementary data
Open the PDF for in another window
Add to Citation Manager
STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells
Yue Li; Weiren Liu; Xiaqun Guan; Jamie Truscott; John W. Creemers; Hung-Lin Chen; Marko Pesu; Rami G. El Abiad; Bahri Karacay; Joseph F. Urban, Jr.; David E. Elliott; Mark H. Kaplan; Bruce R. Blazar; M. Nedim Ince
J Immunol (2018) 201 (9): 2612–2623.
View articletitled, STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells
Supplementary data
Open the PDF for in another window
Add to Citation Manager
HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton–Mediated T Cell Functions
Iratxe del Río-Iñiguez; Elena Vázquez-Chávez; Céline Cuche; Vincenzo Di Bartolo; Jérôme Bouchet; Andrés Alcover
J Immunol (2018) 201 (9): 2624–2640.
View articletitled, HIV-1 Nef Hijacks Lck and Rac1 Endosomal Traffic To Dually Modulate Signaling-Mediated and Actin Cytoskeleton–Mediated T Cell Functions
Supplementary data
Open the PDF for in another window
Add to Citation Manager
B Cell–Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses
Melissa M. Walker; Bergren W. Crute; John C. Cambier; Andrew Getahun
J Immunol (2018) 201 (9): 2641–2653.
View articletitled, B Cell–Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis
Maya Imbrechts; Anneleen Avau; Jessica Vandenhaute; Bert Malengier-Devlies; Karen Put; Tania Mitera; Nele Berghmans; Oliver Burton; Steffie Junius; Adrian Liston; Lien de Somer; Carine Wouters; Patrick Matthys
J Immunol (2018) 201 (9): 2654–2663.
View articletitled, Insufficient IL-10 Production as a Mechanism Underlying the Pathogenesis of Systemic Juvenile Idiopathic Arthritis
Supplementary data
Open the PDF for in another window
Add to Citation Manager

IMMUNE SYSTEM DEVELOPMENT

Peroxisome Proliferator-Activated Receptor–δ Supports the Metabolic Requirements of Cell Growth in TCRβ-Selected Thymocytes and Peripheral CD4+ T Cells
Fei Linda Zhao; Jeeyoon Jennifer Ahn; Edward L. Y. Chen; Tae Joon Yi; Natalie H. Stickle; David Spaner; Juan Carlos Zúñiga-Pflücker; Shannon E. Dunn
J Immunol (2018) 201 (9): 2664–2682.
View articletitled, Peroxisome Proliferator-Activated Receptor–δ Supports the Metabolic Requirements of Cell Growth in TCRβ-Selected Thymocytes and Peripheral CD4<sup>+</sup> T Cells
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus
Clare Pridans; Anna Raper; Gemma M. Davis; Joana Alves; Kristin A. Sauter; Lucas Lefevre; Tim Regan; Stephen Meek; Linda Sutherland; Alison J. Thomson; Sara Clohisey; Stephen J. Bush; Rocío Rojo; Zofia M. Lisowski; Robert Wallace; Kathleen Grabert; Kyle R. Upton; Yi Ting Tsai; Deborah Brown; Lee B. Smith; Kim M. Summers; Neil A. Mabbott; Pedro Piccardo; Michael T. Cheeseman; Tom Burdon; David A. Hume
J Immunol (2018) 201 (9): 2683–2699.
View articletitled, Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the <em>Csf1r</em> Locus
Supplementary data
Open the PDF for in another window
Add to Citation Manager

IMMUNOTHERAPY AND VACCINES

Human Factor H Domains 6 and 7 Fused to IgG1 Fc Are Immunotherapeutic against Neisseria gonorrhoeae
Jutamas Shaughnessy; Lisa A. Lewis; Bo Zheng; Caleb Carr; Isaac Bass; Sunita Gulati; Rosane B. DeOliveira; Severin Gose; George W. Reed; Marina Botto; Peter A. Rice; Sanjay Ram
J Immunol (2018) 201 (9): 2700–2709.
View articletitled, Human Factor H Domains 6 and 7 Fused to IgG1 Fc Are Immunotherapeutic against <em>Neisseria gonorrhoeae</em>
Supplementary data
Open the PDF for in another window
Add to Citation Manager

INFECTIOUS DISEASE AND HOST RESPONSE

Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets
Fangfang Bai; Ryan M. McCormack; Suzanne Hower; Gregory V. Plano; Mathias G. Lichtenheld; George P. Munson
J Immunol (2018) 201 (9): 2710–2720.
View articletitled, Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Short Leucine-Rich Proteoglycans Modulate Complement Activity and Increase Killing of the Respiratory Pathogen Moraxella catarrhalis
Maisem Laabei; Guanghui Liu; David Ermert; John D. Lambris; Kristian Riesbeck; Anna M. Blom
J Immunol (2018) 201 (9): 2721–2730.
View articletitled, Short Leucine-Rich Proteoglycans Modulate Complement Activity and Increase Killing of the Respiratory Pathogen <em>Moraxella catarrhalis</em>
Supplementary data
Open the PDF for in another window
Add to Citation Manager
HIV-1 Nef Disrupts CD4+ T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface
Miguel Lamas-Murua; Bettina Stolp; Sheetal Kaw; Judith Thoma; Nikolaos Tsopoulidis; Birthe Trautz; Ina Ambiel; Tatjana Reif; Sakshi Arora; Andrea Imle; Nadine Tibroni; Jingxia Wu; Guoliang Cui; Jens V. Stein; Motomu Tanaka; Ruth Lyck; Oliver T. Fackler
J Immunol (2018) 201 (9): 2731–2743.
View articletitled, HIV-1 Nef Disrupts CD4<sup>+</sup> T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy
Alexander Badamchi-Zadeh; Kelly D. Moynihan; Rafael A. Larocca; Malika Aid; Nicholas M. Provine; M. Justin Iampietro; Ekaterina Kinnear; Pablo Penaloza-MacMaster; Peter Abbink; Eryn Blass; John S. Tregoning; Darrell J. Irvine; Dan H. Barouch
J Immunol (2018) 201 (9): 2744–2752.
View articletitled, Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Proinflammatory Effects of Respiratory Syncytial Virus–Induced Epithelial HMGB1 on Human Innate Immune Cell Activation
Kempaiah Rayavara; Alexander Kurosky; Susan J. Stafford; Nisha J. Garg; Allan R. Brasier; Roberto P. Garofalo; Yashoda M. Hosakote
J Immunol (2018) 201 (9): 2753–2766.
View articletitled, Proinflammatory Effects of Respiratory Syncytial Virus–Induced Epithelial HMGB1 on Human Innate Immune Cell Activation
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Aspergillus fumigatus Infection
Yan Sun; Serena Abbondante; Mausita Karmakar; Steven de Jesus Carrion; Chengye Che; Amy G. Hise; Eric Pearlman
J Immunol (2018) 201 (9): 2767–2775.
View articletitled, Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in <em>Aspergillus fumigatus</em> Infection
Supplementary data
Open the PDF for in another window
Add to Citation Manager

INNATE IMMUNITY AND INFLAMMATION

Diversification of Bw4 Specificity and Recognition of a Nonclassical MHC Class I Molecule Implicated in Maternal–Fetal Tolerance by Killer Cell Ig-like Receptors of the Rhesus Macaque
Priyankana Banerjee; Moritz Ries; Sanath Kumar Janaka; Andres G. Grandea, III; Roger Wiseman; David H. O’Connor; Thaddeus G. Golos; David T. Evans
J Immunol (2018) 201 (9): 2776–2786.
View articletitled, Diversification of Bw4 Specificity and Recognition of a Nonclassical MHC Class I Molecule Implicated in Maternal–Fetal Tolerance by Killer Cell Ig-like Receptors of the Rhesus Macaque
Open the PDF for in another window
Add to Citation Manager
IL-33 Upregulates Cysteinyl Leukotriene Receptor Type 1 Expression in Human Peripheral Blood CD4+ T Lymphocytes
Marie Boudaud; Sylvie Turcotte; Jana Stankova; Marek Rola-Pleszczynski
J Immunol (2018) 201 (9): 2787–2798.
View articletitled, IL-33 Upregulates Cysteinyl Leukotriene Receptor Type 1 Expression in Human Peripheral Blood CD4<sup>+</sup> T Lymphocytes
Supplementary data
Open the PDF for in another window
Add to Citation Manager

SYSTEMS IMMUNOLOGY

The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation
Robert R. Haines; Benjamin G. Barwick; Christopher D. Scharer; Parimal Majumder; Troy D. Randall; Jeremy M. Boss
J Immunol (2018) 201 (9): 2799–2811.
View articletitled, The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation
Supplementary data
Open the PDF for in another window
Add to Citation Manager

TRANSPLANTATION

Stabilization of Foxp3 by Targeting JAK2 Enhances Efficacy of CD8 Induced Regulatory T Cells in the Prevention of Graft-versus-Host Disease
Supinya Iamsawat; Anusara Daenthanasanmak; Jessica Heinrichs Voss; Hung Nguyen; David Bastian; Chen Liu; Xue-Zhong Yu
J Immunol (2018) 201 (9): 2812–2823.
View articletitled, Stabilization of Foxp3 by Targeting JAK2 Enhances Efficacy of CD8 Induced Regulatory T Cells in the Prevention of Graft-versus-Host Disease
Supplementary data
Open the PDF for in another window
Add to Citation Manager

TUMOR IMMUNOLOGY

EF Hand Domain Family Member D2 Is Required for T Cell Cytotoxicity
Michael Peled; Matthew A. Dragovich; Kieran Adam; Marianne Strazza; Anna S. Tocheva; Irving E. Vega; Adam Mor
J Immunol (2018) 201 (9): 2824–2831.
View articletitled, EF Hand Domain Family Member D2 Is Required for T Cell Cytotoxicity
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Lysyl–Transfer RNA Synthetase Induces the Maturation of Dendritic Cells through MAPK and NF-κB Pathways, Strongly Contributing to Enhanced Th1 Cell Responses
Hui Xuan Lim; Hak-Jun Jung; Arim Lee; Si Hoon Park; Byung Woo Han; Daeho Cho; Tae Sung Kim
J Immunol (2018) 201 (9): 2832–2841.
View articletitled, Lysyl–Transfer RNA Synthetase Induces the Maturation of Dendritic Cells through MAPK and NF-κB Pathways, Strongly Contributing to Enhanced Th1 Cell Responses
Supplementary data
Open the PDF for in another window
Add to Citation Manager
Inhaled IL-10 Suppresses Lung Tumorigenesis via Abrogation of Inflammatory Macrophage–Th17 Cell Axis
Qingsheng Li; Charles D. Anderson; Nejat K. Egilmez
J Immunol (2018) 201 (9): 2842–2850.
View articletitled, Inhaled IL-10 Suppresses Lung Tumorigenesis via Abrogation of Inflammatory Macrophage–Th17 Cell Axis
Supplementary data
Open the PDF for in another window
Add to Citation Manager
  • Cover Image

    Cover Image

    issue cover

    On the cover: Deletion of Csf1r in rats causes male infertility. Shown is an H&E-stained section of epididymides from an adult Csf1r-deficient rat. Pridans, C., A. Raper, G. M. Davis, J. Alves, K. A. Sauter, L. Lefevre, T. Regan, S. Meek, L. Sutherland, A. J. Thomson, S. Clohisey, S. J. Bush, R. Rojo, Z. M. Lisowski, R. Wallace, K. Grabert, K. R. Upton, Y. T. Tsai, D. Brown, L. B. Smith, K. M. Summers, N. A. Mabbott, P. Piccardo, M. T. Cheeseman, T. Burdon, and D. A. Hume. 2018. Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus. J. Immunol. 201: 2683–2699.

  • PDF Icon PDF LinkFront Matter
  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkBack Matter
  • PDF Icon PDF LinkAdvertising
  • PDF Icon PDF LinkEditorial Board
All Issues

Advertisement

Advertisement

Advertisement

  • Online ISSN 1550-6606
  • Print ISSN 0022-1767

Publications

Submit a Manuscript

General Information

Journal Services

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.
Accept