Issues

Rasgrp1 is necessary for TCR/CD28-induced Ras–ERK in murine peripheral CD4⁺ T cells.

TCR/CD28-induced CD4⁺ T cell IL-2 and IL-2R expression is dependent on Rasgrp1.

TCR/CD28-induced CD4⁺ T cell proliferation is severely impacted by Rasgrp1 deficiency.

Very few B cells can adhere to activated human endothelial cells under flow.

Chemokines and BCR signals can trigger morphologically distinct mechanisms of TEM.

Furthermore, BCR signals select a rare innate-like memory subset.

α-d-Glu induces DC homing to improve the antitumor effect of neoantigens vaccines.

α-d-Glu promotes DC migration comparable with PGE₂.

α-d-Glu promotes DC migration by inhibiting microRNA10a-5p and activating Erk1/2.

B cell Ag presentation to CD4s via MHCII is required for PLP_ECD EAE disease.

B cells promote CD4 proliferation, cytokine production, and pathogenicity.

PLP_ECD EAE is susceptible to B cell depletion therapy.

DNAM-1 protects mice from Con A–induced acute liver injury.

DNAM-1 reduces neutrophil infiltration in Con A–induced acute liver injury.

CD155 on hepatocytes inhibits CXCL1 production in Con A–induced acute liver injury.

Three functional IgMs are present in grass carp.

The landscape of grass carp IgM⁺ B cells is revealed by scRNA-seq.

Single IgM⁺ B cells express multiple Igμ genes with distinct V_HDJ_H recombination patterns.

The SD1 domain is essential for the SARS-CoV-2 RBD to elicit immunogenicity.

Addition of human Fc receptor to RBDSD1 (RBDSD1Fc) enhances immunogenicity.

An RBDSD1Fc subunit vaccine protects hACE2 knock-in mice against SARS-CoV-2 challenge.

B. burgdorferi Arp_152–166-containing MHC II tetramers identify Arp-specific CD4 T cells.

Labeled tetramerized Arp identifies small numbers of Arp B cells after B. burgdorferi infection.

Data indicate a failure to maintain but not to induce an Arp response after infection.

gcLXRα promotes the replication and infection of GCRV.

gcLXRα heterodimerizes with RXRga and RXRgb.

gcLXRα impairs formation of the IRF3/CBP transcription complex.

Host RTCB is significantly downregulated during influenza A viral infection.

Influenza A virus propagation is affected by RTCB knockout.

RTCB competitively binds DDX1, attenuating its association with DDX21.

4-OI and DMF induce annexin A1 secretion in LPS-stimulated macrophages.

The induction of annexin A1 secretion by 4-OI and DMF requires ABCA1 and NRF2.

4-OI induces annexin A1 secretion in vivo.

A nonrearranging Ig gene, UrIg, is discovered that maps to the shark MHC.

UrIg is a four-domain dimer expressed by the liver, and the protein is found in the ECM.

UrIg may predate invasion of an Ig superfamily gene by the RAG transposon.

High IL-1β levels in the intestine are associated with an increased survival time.

Intestinal IL-1β is associated with a reduced intestinal viral load.

Intestinal IL-1β is associated with increased levels of intestinal type I IFNs.