Issues

TER119 ameliorates murine ITP while triggering adverse inflammation.

PAF-R antagonist mitigates TER119-induced temperature change and cytokine release.

Phagocytes and functional TER119 Fc are required for TER119-induced inflammation.

Coinhibitory receptors are associated with B cell dysregulation.

Metabolomic alteration and elevated IL-6 contribute to B cell dysfunction.

The spike protein promotes B cell apoptosis in COVID-19 patients.

FcRg- Adaptive NK cells are expanded very early in acute HIV infection.

NK cell dysfunction persists despite early ART initiation.

Adaptive NK cells are associated with HIV DNA levels.

NK cells progress along a spectrum of differentiation in PWH on long-term ART.

Conventional but not FcRγ^– NK cells downregulate KLRG1 upon IL-18+IL-12 exposure.

PWH display atypical NK cell subsets, representing intermediate stages of NK-poiesis.

Using paired BCR sequences improves accuracy and reproducibility of lineage trees.

Multipartition models outperform other methods when some L chains are missing.

These methods are available in the R package Dowser.

A tumor-specific complement-activating Ab, GT103, enhances antitumor immunity.

GT103 inhibits immunosuppression and promotes effector T cell activation in the TME.

A human autoantibody targeting the GT103 epitope enhances antitumor immunity in situ.