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Deletion of protein kinase D1 in myeloid lineage cells suppresses development of IFNγ ⁺IL-17A ⁺CD4 T cells and ameliorates hypersensitivity pneumonitis

Ae-Kyung Yi, John D Snyder, Tae Won Yoon, Elizabeth A Fitzpatrick

J Immunol (2023) 210 (1_Supplement): 67.19.

https://doi.org/10.4049/jimmunol.210.Supp.67.19

Published: 01 May 2023

View article titled, Deletion of protein kinase D1 in myeloid lineage cells suppresses development of IFNγ +IL-17A +CD4 T cells and ameliorates hypersensitivity pneumonitis

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MyD88 and PKD1 play an essential role in the development of spontaneous polyarthritis in IL-1 receptor antagonist-deficient mice

Taewon Yoon, Hongsik Cho, John M Stuart, Ae-Kyung Yi

J Immunol (2019) 202 (1_Supplement): 133.18.

https://doi.org/10.4049/jimmunol.202.Supp.133.18

Published: 01 May 2019

View article titled, MyD88 and PKD1 play an essential role in the development of spontaneous polyarthritis in IL-1 receptor antagonist-deficient mice

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Indispensable role of protein kinase D1 in inflammatory responses and host defense in Group B streptococci infection

Taewon Yoon, Priyanka Halder, Ae-Kyung Yi

J Immunol (2018) 200 (1_Supplement): 50.16.

https://doi.org/10.4049/jimmunol.200.Supp.50.16

Published: 01 May 2018

View article titled, Indispensable role of protein kinase D1 in inflammatory responses and host defense in Group B streptococci infection

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Protein Kinase D1 deletion ameliorates collage-induced arthritis

Taewon Yoon, Hongsik Cho, John M. Stuart, Ae-Kyung Yi

J Immunol (2018) 200 (1_Supplement): 175.8.

https://doi.org/10.4049/jimmunol.200.Supp.175.8

Published: 01 May 2018

View article titled, Protein Kinase D1 deletion ameliorates collage-induced arthritis

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Group B Streptococci Induce Proinflammatory Responses via a Protein Kinase D1–Dependent Pathway

Kirtikumar Upadhyay, Jeoung-Eun Park, Tae Won Yoon, Priyanka Halder, Young-In Kim, Victoria Metcalfe, Ajay J. Talati, B. Keith English, Ae-Kyung Yi

J Immunol (2017) 198 (11): 4448–4457.

https://doi.org/10.4049/jimmunol.1601089

Published: 01 June 2017

View article titled, Group B Streptococci Induce Proinflammatory Responses via a Protein Kinase D1–Dependent Pathway

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MyD88-dependent activation of protein kinase D1 is essential for Group B streptococci-induced proinflammatory responses

Ae-Kyung Yi, Tae Won Yoon, Kirtikumar Upadhyay, Jeoung-Eun Park, Young-In Kim, Victoria Metcalfe, Priyanka Halder, Ajay J. Talati

J Immunol (2017) 198 (1_Supplement): 148.19.

https://doi.org/10.4049/jimmunol.198.Supp.148.19

Published: 01 May 2017

View article titled, MyD88-dependent activation of protein kinase D1 is essential for Group B streptococci-induced proinflammatory responses

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Journal Articles

A pharmacological protein kinase C/D inhibitor Gö6976 ameliorates collagen-induced arthritis

Taewon Yoon, Hongsik Cho, Young-In Kim, David Brand, Karen Hasty, John Stuart, Ae-Kyung Yi

J Immunol (2017) 198 (1_Supplement): 127.28.

https://doi.org/10.4049/jimmunol.198.Supp.127.28

Published: 01 May 2017

View article titled, A pharmacological protein kinase C/D inhibitor Gö6976 ameliorates collagen-induced arthritis

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Effect of genetics on the development of Hypersensitivity Pneumonitis (HP) using the BXD recombinant inbred mouse reference population

Elizabeth Fitzpatrick, Tae-Won Yoon, Robert Williams, Ae-Kyung Yi

J Immunol (2017) 198 (1_Supplement): 53.10.

https://doi.org/10.4049/jimmunol.198.Supp.53.10

Published: 01 May 2017

View article titled, Effect of genetics on the development of Hypersensitivity Pneumonitis (HP) using the BXD recombinant inbred mouse reference population

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Protein kinase D1 is essential for Saccharopolyspora rectivirgula-induced pulmonary inflammation and alveolitis.

Taewon Yoon, Young-In Kim, Elizabeth Fitzpatrick, Ae-Kyung Yi

J Immunol (2017) 198 (1_Supplement): 148.18.

https://doi.org/10.4049/jimmunol.198.Supp.148.18

Published: 01 May 2017

View article titled, Protein kinase D1 is essential for Saccharopolyspora rectivirgula-induced pulmonary inflammation and alveolitis.

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Characterization of the Syk-Dependent T Cell Signaling Response to an Altered Peptide

Jeoung-Eun Park, Jeffrey A. Rotondo, David L. Cullins, David D. Brand, Ae-Kyung Yi, John M. Stuart, Andrew H. Kang, Linda K. Myers

J Immunol (2016) 197 (12): 4569–4575.

https://doi.org/10.4049/jimmunol.1600771

Published: 15 December 2016

View article titled, Characterization of the Syk-Dependent T Cell Signaling Response to an Altered Peptide

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MyD88-dependent PKD1 is essential for development of polyarthritis spontaneously occurring in IL-1R antagonist-deficient mice.

Ae-Kyung Yi, Tae Won Yoon, Hongsik Cho, Jeoung-Eun Park, Karen A Hasty, John M Stuart

J Immunol (2016) 196 (1_Supplement): 210.2.

https://doi.org/10.4049/jimmunol.196.Supp.210.2

Published: 01 May 2016

View article titled, MyD88-dependent PKD1 is essential for development of polyarthritis spontaneously occurring in IL-1R antagonist-deficient mice.

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Journal Articles

Group B streptococci induce proinflammatory responses via a protein kinase D1-dependent pathway (INM7P.351)

Ae-Kyung Yi, Kirtikumar Upadhyay, Jeoung-Eun Park, Young-In Kim-Hoehamer, Ajay Talati, B. English

J Immunol (2015) 194 (1_Supplement): 194.8.

https://doi.org/10.4049/jimmunol.194.Supp.194.8

Published: 01 May 2015

View article titled, Group B streptococci induce proinflammatory responses via a protein kinase D1-dependent pathway (INM7P.351)

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Contribution of MyD88-dependent PKD1 to the development of arthritis (THER2P.954)

Ae-Kyung Yi, Tae Won Yoon, Hongsik Cho, David Brand, Young-In Kim-Hoehamer, Jeoung-Eun Park, Karen Hasty, John Stuart

J Immunol (2015) 194 (1_Supplement): 67.5.

https://doi.org/10.4049/jimmunol.194.Supp.67.5

Published: 01 May 2015

View article titled, Contribution of MyD88-dependent PKD1 to the development of arthritis (THER2P.954)

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Journal Articles

IFNγ-mediated exacerbation of Saccharopolyspora rectivirgula-induced proinflammatory responses is dependent on interferon regulatory factor 1 (INM3P.403)

Ae-Kyung Yi, Jeoung-Eun Park

J Immunol (2015) 194 (1_Supplement): 127.8.

https://doi.org/10.4049/jimmunol.194.Supp.127.8

Published: 01 May 2015

View article titled, IFNγ-mediated exacerbation of Saccharopolyspora rectivirgula-induced proinflammatory responses is dependent on interferon regulatory factor 1 (INM3P.403)

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Protein kinase D1 links IRAK1 and TRAF6 in the MyD88-dependent Toll-like receptor signaling pathway. (INM9P.457)

Ae-Kyung Yi, Jeoung-Eun Park, Young-In Kim

J Immunol (2014) 192 (1_Supplement): 189.10.

https://doi.org/10.4049/jimmunol.192.Supp.189.10

Published: 01 May 2014

View article titled, Protein kinase D1 links IRAK1 and TRAF6 in the MyD88-dependent Toll-like receptor signaling pathway. (INM9P.457)

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A pharmacological protein kinase D inhibitor ameliorates experimental arthritis. (THER6P.850)

Ae-Kyung Yi, Tae Won Yoon, David Brand, Young-In Kim, Jeoung-Eun Park, John Stuart

J Immunol (2014) 192 (1_Supplement): 201.6.

https://doi.org/10.4049/jimmunol.192.Supp.201.6

Published: 01 May 2014

View article titled, A pharmacological protein kinase D inhibitor ameliorates experimental arthritis. (THER6P.850)

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Journal Articles

Protein Kinase D1 Is Essential for the Proinflammatory Response Induced by Hypersensitivity Pneumonitis-Causing Thermophilic Actinomycetes Saccharopolyspora rectivirgula

Young-In Kim, Jeoung-Eun Park, David D. Brand, Elizabeth A. Fitzpatrick, Ae-Kyung Yi

J Immunol (2010) 184 (6): 3145–3156.

https://doi.org/10.4049/jimmunol.0903718

Published: 15 March 2010

View article titled, Protein Kinase D1 Is Essential for the Proinflammatory Response Induced by Hypersensitivity Pneumonitis-Causing Thermophilic Actinomycetes Saccharopolyspora rectivirgula

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Journal Articles

Protein Kinase D1 Is Essential for MyD88-Dependent TLR Signaling Pathway

Jeoung-Eun Park, Young-In Kim, Ae-Kyung Yi

J Immunol (2009) 182 (10): 6316–6327.

https://doi.org/10.4049/jimmunol.0804239

Published: 15 May 2009

View article titled, Protein Kinase D1 Is Essential for MyD88-Dependent TLR Signaling Pathway

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Journal Articles

Protein Kinase D1: A New Component in TLR9 Signaling

Jeoung-Eun Park, Young-In Kim, Ae-Kyung Yi

J Immunol (2008) 181 (3): 2044–2055.

https://doi.org/10.4049/jimmunol.181.3.2044

Published: 01 August 2008

View article titled, Protein Kinase D1: A New Component in TLR9 Signaling

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Journal Articles

CpG DNA Induces Self and Cross-Hyporesponsiveness of RAW264.7 Cells in Response to CpG DNA and Lipopolysaccharide: Alterations in IL-1 Receptor-Associated Kinase Expression

Seon-Ju Yeo, Jae-Geun Yoon, Soon-Cheol Hong, Ae-Kyung Yi

J Immunol (2003) 170 (2): 1052–1061.

https://doi.org/10.4049/jimmunol.170.2.1052

Published: 15 January 2003

View article titled, CpG DNA Induces Self and Cross-Hyporesponsiveness of RAW264.7 Cells in Response to CpG DNA and Lipopolysaccharide: Alterations in IL-1 Receptor-Associated Kinase Expression

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NARROW

Deletion of protein kinase D1 in myeloid lineage cells suppresses development of IFNγ ⁺IL-17A ⁺CD4 T cells and ameliorates hypersensitivity pneumonitis

MyD88 and PKD1 play an essential role in the development of spontaneous polyarthritis in IL-1 receptor antagonist-deficient mice

Indispensable role of protein kinase D1 in inflammatory responses and host defense in Group B streptococci infection

Protein Kinase D1 deletion ameliorates collage-induced arthritis

Group B Streptococci Induce Proinflammatory Responses via a Protein Kinase D1–Dependent Pathway

MyD88-dependent activation of protein kinase D1 is essential for Group B streptococci-induced proinflammatory responses

A pharmacological protein kinase C/D inhibitor Gö6976 ameliorates collagen-induced arthritis

Effect of genetics on the development of Hypersensitivity Pneumonitis (HP) using the BXD recombinant inbred mouse reference population

Protein kinase D1 is essential for Saccharopolyspora rectivirgula-induced pulmonary inflammation and alveolitis.

Characterization of the Syk-Dependent T Cell Signaling Response to an Altered Peptide

MyD88-dependent PKD1 is essential for development of polyarthritis spontaneously occurring in IL-1R antagonist-deficient mice.

Group B streptococci induce proinflammatory responses via a protein kinase D1-dependent pathway (INM7P.351)

Contribution of MyD88-dependent PKD1 to the development of arthritis (THER2P.954)

IFNγ-mediated exacerbation of Saccharopolyspora rectivirgula-induced proinflammatory responses is dependent on interferon regulatory factor 1 (INM3P.403)

Protein kinase D1 links IRAK1 and TRAF6 in the MyD88-dependent Toll-like receptor signaling pathway. (INM9P.457)

A pharmacological protein kinase D inhibitor ameliorates experimental arthritis. (THER6P.850)

Protein Kinase D1 Is Essential for the Proinflammatory Response Induced by Hypersensitivity Pneumonitis-Causing Thermophilic Actinomycetes Saccharopolyspora rectivirgula

Protein Kinase D1 Is Essential for MyD88-Dependent TLR Signaling Pathway

Protein Kinase D1: A New Component in TLR9 Signaling

CpG DNA Induces Self and Cross-Hyporesponsiveness of RAW264.7 Cells in Response to CpG DNA and Lipopolysaccharide: Alterations in IL-1 Receptor-Associated Kinase Expression

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