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Akihiko Yoshimura
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Journal Articles

STAP-2–Derived Peptide Suppresses TCR-Mediated Signals to Initiate Immune Responses

Yuto Sasaki, Kodai Saitoh, Kota Kagohashi, Toyoyuki Ose, Shoya Kawahara, Yuichi Kitai, Ryuta Muromoto, Yuichi Sekine, Michiko Ichii, Akihiko Yoshimura, Kenji Oritani, Jun-ichi Kashiwakura, Tadashi Matsuda
Journal: The Journal of Immunology
J Immunol (2023) 211 (5): 755–766.
https://doi.org/10.4049/jimmunol.2200942
Published: 07 July 2023
View article titled, STAP-2–Derived Peptide Suppresses TCR-Mediated Signals to Initiate Immune Responses
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Includes: Supplementary data
Journal Articles

Memory B Cells and Memory T Cells Induced by SARS-CoV-2 Booster Vaccination or Infection Show Different Dynamics and Responsiveness to the Omicron Variant

In Special Collection:
COVID-19, SARS, and MERS Articles
Setsuko Mise-Omata, Mari Ikeda, Masaru Takeshita, Yoshifumi Uwamino, Masatoshi Wakui, Tomoko Arai, Ayumi Yoshifuji, Kensaku Murano, Haruhiko Siomi, Kensuke Nakagawara, Masaki Ohyagi, Makoto Ando, Naoki Hasegawa, Hideyuki Saya, Mitsuru Murata, Koichi Fukunaga, Ho Namkoong, Xiuyuan Lu, Sho Yamasaki, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2022) 209 (11): 2104–2113.
https://doi.org/10.4049/jimmunol.2200525
Published: 01 December 2022
View article titled, Memory B Cells and Memory T Cells Induced by SARS-CoV-2 Booster Vaccination or Infection Show Different Dynamics and Responsiveness to the Omicron Variant
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Includes: Supplementary data
Journal Articles

STAP-2 Is a Novel Positive Regulator of TCR-Proximal Signals

Kodai Saitoh, Jun-ichi Kashiwakura, Kota Kagohashi, Yuto Sasaki, Shoya Kawahara, Yuichi Sekine, Yuichi Kitai, Ryuta Muromoto, Michiko Ichii, Hiroko Nakatsukasa, Akihiko Yoshimura, Kenji Oritani, Tadashi Matsuda
Journal: The Journal of Immunology
J Immunol (2022) 209 (1): 57–68.
https://doi.org/10.4049/jimmunol.2101014
Published: 01 July 2022
View article titled, STAP-2 Is a Novel Positive Regulator of TCR-Proximal Signals
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Includes: Supplementary data
Journal Articles

Essential Roles of the Transcription Factor NR4A1 in Regulatory T Cell Differentiation under the Influence of Immunosuppressants

Takashi Sekiya, Hidenori Kasahara, Ryo Takemura, Shinya Fujita, Jun Kato, Noriko Doki, Yuta Katayama, Yukiyasu Ozawa, Satoru Takada, Tetsuya Eto, Takahiro Fukuda, Tatsuo Ichinohe, Minoko Takanashi, Makoto Onizuka, Yoshiko Atsuta, Shinichiro Okamoto, Akihiko Yoshimura, Satoshi Takaki, Takehiko Mori
Journal: The Journal of Immunology
J Immunol (2022) 208 (9): 2122–2130.
https://doi.org/10.4049/jimmunol.2100808
Published: 01 May 2022
View article titled, Essential Roles of the Transcription Factor NR4A1 in Regulatory T Cell Differentiation under the Influence of Immunosuppressants
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Includes: Supplementary data
Journal Articles

TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus

Shunsuke Chikuma, Soichiro Yamanaka, So Nakagawa, Mahoko Takahashi Ueda, Hodaka Hayabuchi, Yukiko Tokifuji, Masashi Kanayama, Tadashi Okamura, Hisashi Arase, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2021) 206 (7): 1528–1539.
https://doi.org/10.4049/jimmunol.2001003
Published: 01 April 2021
View article titled, TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus
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Includes: Supplementary data
Journal Articles

SOCS1 Is a Key Molecule That Prevents Regulatory T Cell Plasticity under Inflammatory Conditions

Reiko Takahashi, Hiroko Nakatsukasa, Shunichi Shiozawa, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2017) 199 (1): 149–158.
https://doi.org/10.4049/jimmunol.1600441
Published: 01 July 2017
View article titled, SOCS1 Is a Key Molecule That Prevents Regulatory T Cell Plasticity under Inflammatory Conditions
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Includes: Supplementary data
Journal Articles

TET2 and TET3 regulate stability and function of regulatory T cells.

Hiroko Nakatsukasa, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 212.7.
https://doi.org/10.4049/jimmunol.198.Supp.212.7
Published: 01 May 2017
View article titled, TET2 and TET3 regulate stability and function of regulatory T cells.
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Journal Articles

Spred1, a Suppressor of the Ras–ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells

Mayu Suzuki, Rimpei Morita, Yasuko Hirata, Takashi Shichita, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2015) 195 (3): 1273–1281.
https://doi.org/10.4049/jimmunol.1500531
Published: 01 August 2015
View article titled, Spred1, a Suppressor of the Ras–ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells
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Includes: Supplementary data
Journal Articles

Anti–IL-12/23 p40 Antibody Attenuates Experimental Chronic Graft-versus-Host Disease via Suppression of IFN-γ/IL-17–Producing Cells

Sachiyo Okamoto, Hideaki Fujiwara, Hisakazu Nishimori, Ken-ichi Matsuoka, Nobuharu Fujii, Eisei Kondo, Takehiro Tanaka, Akihiko Yoshimura, Mitsune Tanimoto, Yoshinobu Maeda
Journal: The Journal of Immunology
J Immunol (2015) 194 (3): 1357–1363.
https://doi.org/10.4049/jimmunol.1400973
Published: 01 February 2015
View article titled, Anti–IL-12/23 p40 Antibody Attenuates Experimental Chronic Graft-versus-Host Disease via Suppression of IFN-γ/IL-17–Producing Cells
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Journal Articles

Signal-Transducing Adaptor Protein-2 Controls the IgE-Mediated, Mast Cell–Mediated Anaphylactic Responses

Yuichi Sekine, Keigo Nishida, Satoru Yamasaki, Ryuta Muromoto, Shigeyuki Kon, Jun-ichi Kashiwakura, Kodai Saitoh, Sumihito Togi, Akihiko Yoshimura, Kenji Oritani, Tadashi Matsuda
Journal: The Journal of Immunology
J Immunol (2014) 192 (8): 3488–3495.
https://doi.org/10.4049/jimmunol.1300886
Published: 15 April 2014
View article titled, Signal-Transducing Adaptor Protein-2 Controls the IgE-Mediated, Mast Cell–Mediated Anaphylactic Responses
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Includes: Supplementary data
Journal Articles

Th17 Cells Carrying TCR Recognizing Epidermal Autoantigen Induce Psoriasis-like Skin Inflammation

Shuhei Nishimoto, Hitoshi Kotani, Sanae Tsuruta, Nana Shimizu, Minako Ito, Takashi Shichita, Rimpei Morita, Hayato Takahashi, Masayuki Amagai, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2013) 191 (6): 3065–3072.
https://doi.org/10.4049/jimmunol.1300348
Published: 15 September 2013
View article titled, Th17 Cells Carrying TCR Recognizing Epidermal Autoantigen Induce Psoriasis-like Skin Inflammation
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Includes: Supplementary data
Journal Articles

Smad2/3 and IRF4 Play a Cooperative Role in IL-9–Producing T Cell Induction

Taiga Tamiya, Kenji Ichiyama, Hitoshi Kotani, Tomohiro Fukaya, Takashi Sekiya, Takashi Shichita, Kiri Honma, Katsuyuki Yui, Toshifumi Matsuyama, Takako Nakao, Satoru Fukuyama, Hiromasa Inoue, Masatoshi Nomura, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2360–2371.
https://doi.org/10.4049/jimmunol.1301276
Published: 01 September 2013
View article titled, Smad2/3 and IRF4 Play a Cooperative Role in IL-9–Producing T Cell Induction
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Journal Articles

IL-23–Independent Induction of IL-17 from γδT Cells and Innate Lymphoid Cells Promotes Experimental Intraocular Neovascularization

Eiichi Hasegawa, Koh-Hei Sonoda, Takashi Shichita, Rimpei Morita, Takashi Sekiya, Akihiro Kimura, Yuji Oshima, Atsunobu Takeda, Takeru Yoshimura, Shigeo Yoshida, Tatsuro Ishibashi, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2013) 190 (4): 1778–1787.
https://doi.org/10.4049/jimmunol.1202495
Published: 15 February 2013
View article titled, IL-23–Independent Induction of IL-17 from γδT Cells and Innate Lymphoid Cells Promotes Experimental Intraocular Neovascularization
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Journal Articles

Signal-Transducing Adaptor Protein-2 Modulates Fas-Mediated T Cell Apoptosis by Interacting with Caspase-8

Yuichi Sekine, Chikako Yamamoto, Michinori Kakisaka, Ryuta Muromoto, Shigeyuki Kon, Dai Ashitomi, Natsuko Fujita, Akihiko Yoshimura, Kenji Oritani, Tadashi Matsuda
Journal: The Journal of Immunology
J Immunol (2012) 188 (12): 6194–6204.
https://doi.org/10.4049/jimmunol.1103467
Published: 15 June 2012
View article titled, Signal-Transducing Adaptor Protein-2 Modulates Fas-Mediated T Cell Apoptosis by Interacting with Caspase-8
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Includes: Supplementary data
Journal Articles

Spred-2 negatively regulates influenza A virus (H1N1)-induced pneumonia (170.11)

Toshihiro Ito, Akihiko Yoshimura, Akihiro Matsukawa
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 170.11.
https://doi.org/10.4049/jimmunol.188.Supp.170.11
Published: 01 May 2012
View article titled, Spred-2 negatively regulates influenza A virus (H1N1)-induced pneumonia (170.11)
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Journal Articles

Pyridone 6, a Pan-JAK Inhibitor, Ameliorates Allergic Skin Inflammation of NC/Nga Mice via Suppression of Th2 and Enhancement of Th17

Ryusuke Nakagawa, Hideyuki Yoshida, Mayako Asakawa, Taiga Tamiya, Naoko Inoue, Rimpei Morita, Hiromasa Inoue, Atsuhito Nakao, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2011) 187 (9): 4611–4620.
https://doi.org/10.4049/jimmunol.1100649
Published: 01 November 2011
View article titled, Pyridone 6, a Pan-JAK Inhibitor, Ameliorates Allergic Skin Inflammation of NC/Nga Mice via Suppression of Th2 and Enhancement of Th17
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Includes: Supplementary data
Journal Articles

Correction: Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development

Tomohito Takimoto, Yu Wakabayashi, Takashi Sekiya, Naoko Inoue, Rimpei Morita, Kenji Ichiyama, Reiko Takahashi, Mayako Asakawa, Go Muto, Tomoaki Mori, Eiichi Hasegawa, Saika Shizuya, Toshiro Hara, Masatoshi Nomura, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2011) 186 (1): 632.
https://doi.org/10.4049/jimmunol.1090121
Published: 01 January 2011
View article titled, Correction: Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development
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Journal Articles

Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development

Tomohito Takimoto, Yu Wakabayashi, Takashi Sekiya, Naoko Inoue, Rimpei Morita, Kenji Ichiyama, Reiko Takahashi, Mayako Asakawa, Go Muto, Tomoaki Mori, Eiichi Hasegawa, Saika Shizuya, Toshiro Hara, Masatoshi Nomura, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2010) 185 (2): 842–855.
https://doi.org/10.4049/jimmunol.0904100
Published: 15 July 2010
View article titled, Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development
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Includes: Supplementary data
Journal Articles

Signal-Transducing Adaptor Protein-2 Regulates Stromal Cell-Derived Factor-1α-Induced Chemotaxis in T Cells

Yuichi Sekine, Osamu Ikeda, Satoshi Tsuji, Chikako Yamamoto, Ryuta Muromoto, Asuka Nanbo, Kenji Oritani, Akihiko Yoshimura, Tadashi Matsuda
Journal: The Journal of Immunology
J Immunol (2009) 183 (12): 7966–7974.
https://doi.org/10.4049/jimmunol.0902096
Published: 15 December 2009
View article titled, Signal-Transducing Adaptor Protein-2 Regulates Stromal Cell-Derived Factor-1α-Induced Chemotaxis in T Cells
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Journal Articles

SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis

Mako Nakaya, Masayuki Hashimoto, Ryusuke Nakagawa, Yu Wakabayashi, Takuma Ishizaki, Ichiro Takada, Kyoko Komai, Hiroki Yoshida, Akihiko Yoshimura
Journal: The Journal of Immunology
J Immunol (2009) 183 (11): 7047–7053.
https://doi.org/10.4049/jimmunol.0900547
Published: 01 December 2009
View article titled, SOCS3 in T and NKT Cells Negatively Regulates Cytokine Production and Ameliorates ConA-Induced Hepatitis
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