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Alasdair M. Gilfillan
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Journal Articles

Rictor Negatively Regulates High-Affinity Receptors for IgE-Induced Mast Cell Degranulation

Daniel Smrz, Glenn Cruse, Michael A. Beaven, Arnold Kirshenbaum, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 5924–5932.
https://doi.org/10.4049/jimmunol.1303495
Published: 15 December 2014
View article titled, Rictor Negatively Regulates High-Affinity Receptors for IgE-Induced Mast Cell Degranulation
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Includes: Supplementary data
Journal Articles

IL-33 Induces a Hyporesponsive Phenotype in Human and Mouse Mast Cells

Mi-Yeon Jung, Daniel Smrž, Avanti Desai, Geethani Bandara, Tomonobu Ito, Shoko Iwaki, Jeong-Han Kang, Marcus V. Andrade, Susana C. Hilderbrand, Jared M. Brown, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2013) 190 (2): 531–538.
https://doi.org/10.4049/jimmunol.1201576
Published: 15 January 2013
View article titled, IL-33 Induces a Hyporesponsive Phenotype in Human and Mouse Mast Cells
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Includes: Supplementary data
Journal Articles

The Adaptor 3BP2 Is Required for Early and Late Events in FcεRI Signaling in Human Mast Cells

Erola Ainsua-Enrich, Damiana Álvarez-Errico, Alasdair M. Gilfillan, César Picado, Joan Sayós, Juan Rivera, Margarita Martín
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 2727–2734.
https://doi.org/10.4049/jimmunol.1200380
Published: 15 September 2012
View article titled, The Adaptor 3BP2 Is Required for Early and Late Events in FcεRI Signaling in Human Mast Cells
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Includes: Supplementary data
Journal Articles

Stem Cell Factor Programs the Mast Cell Activation Phenotype

Tomonobu Ito, Daniel Smrž, Mi-Yeon Jung, Geethani Bandara, Avanti Desai, Šárka Smržová, Hye Sun Kuehn, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5428–5437.
https://doi.org/10.4049/jimmunol.1103366
Published: 01 June 2012
View article titled, Stem Cell Factor Programs the Mast Cell Activation Phenotype
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Includes: Supplementary data
Journal Articles

Glycogen Synthase Kinase-3β Is a Prosurvival Signal for the Maintenance of Human Mast Cell Homeostasis

Madeleine Rådinger, Daniel Smrž, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5587–5595.
https://doi.org/10.4049/jimmunol.1101257
Published: 01 December 2011
View article titled, Glycogen Synthase Kinase-3β Is a Prosurvival Signal for the Maintenance of Human Mast Cell Homeostasis
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Journal Articles

CD84 Negatively Regulates IgE High-Affinity Receptor Signaling in Human Mast Cells

Damiana Álvarez-Errico, Irene Oliver-Vila, Erola Ainsua-Enrich, Alasdair M. Gilfillan, César Picado, Joan Sayós, Margarita Martín
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5577–5586.
https://doi.org/10.4049/jimmunol.1101626
Published: 01 December 2011
View article titled, CD84 Negatively Regulates IgE High-Affinity Receptor Signaling in Human Mast Cells
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Includes: Supplementary data
Journal Articles

CD72 Negatively Regulates KIT-Mediated Responses in Human Mast Cells

Tatsuki R. Kataoka, Atsushi Kumanogoh, Geethani Bandara, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2010) 184 (5): 2468–2475.
https://doi.org/10.4049/jimmunol.0902450
Published: 01 March 2010
View article titled, CD72 Negatively Regulates KIT-Mediated Responses in Human Mast Cells
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Journal Articles

Glycogen Synthase Kinase 3β Activation Is a Prerequisite Signal for Cytokine Production and Chemotaxis in Human Mast Cells

Madeleine Rådinger, Hye Sun Kuehn, Mi-Sun Kim, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2010) 184 (2): 564–572.
https://doi.org/10.4049/jimmunol.0902931
Published: 27 December 2009
View article titled, Glycogen Synthase Kinase 3β Activation Is a Prerequisite Signal for Cytokine Production and Chemotaxis in Human Mast Cells
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Includes: Supplementary data
Journal Articles

IgE-FcεRI Interactions Determine HIV Coreceptor Usage and Susceptibility to Infection during Ontogeny of Mast Cells

J. Bruce Sundstrom, Gregory A. Hair, Aftab A. Ansari, W. Evan Secor, Alasdair M. Gilfillan, Dean D. Metcalfe, Arnold S. Kirshenbaum
Journal: The Journal of Immunology
J Immunol (2009) 182 (10): 6401–6409.
https://doi.org/10.4049/jimmunol.0801481
Published: 15 May 2009
View article titled, IgE-FcεRI Interactions Determine HIV Coreceptor Usage and Susceptibility to Infection during Ontogeny of Mast Cells
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Journal Articles

Glycogen Synthase Kinase-3β regulates antigen/SCF-mediated cytokine production and SCF-mediated chemotaxis in human mast cells (93.6)

Madeleine Radinger, Hye Sun Kuehn, Mi-Sun Kim, Dean D Metcalfe, Alasdair M Gilfillan
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 93.6.
https://doi.org/10.4049/jimmunol.182.Supp.93.6
Published: 01 April 2009
View article titled, Glycogen Synthase Kinase-3β regulates antigen/SCF-mediated cytokine production and SCF-mediated chemotaxis in human mast cells (93.6)
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Journal Articles

The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells

Hye Sun Kuehn, Emily J. Swindle, Mi-Sun Kim, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2008) 181 (11): 7706–7712.
https://doi.org/10.4049/jimmunol.181.11.7706
Published: 01 December 2008
View article titled, The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells
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Journal Articles

RGS13 Controls G Protein-Coupled Receptor-Evoked Responses of Human Mast Cells

Geetanjali Bansal, Jeffrey A. DiVietro, Hye Sun Kuehn, Sudhir Rao, Karl H. Nocka, Alasdair M. Gilfillan, Kirk M. Druey
Journal: The Journal of Immunology
J Immunol (2008) 181 (11): 7882–7890.
https://doi.org/10.4049/jimmunol.181.11.7882
Published: 01 December 2008
View article titled, RGS13 Controls G Protein-Coupled Receptor-Evoked Responses of Human Mast Cells
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Journal Articles

Activation and Function of the mTORC1 Pathway in Mast Cells

Mi-Sun Kim, Hye Sun Kuehn, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2008) 180 (7): 4586–4595.
https://doi.org/10.4049/jimmunol.180.7.4586
Published: 01 April 2008
View article titled, Activation and Function of the mTORC1 Pathway in Mast Cells
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Journal Articles

Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line

Hong-Tao Ma, Ze Peng, Takaaki Hiragun, Shoko Iwaki, Alasdair M. Gilfillan, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2008) 180 (4): 2233–2239.
https://doi.org/10.4049/jimmunol.180.4.2233
Published: 15 February 2008
View article titled, Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr<sup>2+</sup> Entry, Optimal Influx of Ca<sup>2+</sup>, and Degranulation in a Rat Mast Cell Line
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Journal Articles

Cutting Edge: Genetic Variation Influences FcεRI-Induced Mast Cell Activation and Allergic Responses

Yumi Yamashita, Nicolas Charles, Yasuko Furumoto, Sandra Odom, Toshiyuki Yamashita, Alasdair M. Gilfillan, Stephanie Constant, Molly A. Bower, John J. Ryan, Juan Rivera
Journal: The Journal of Immunology
J Immunol (2007) 179 (2): 740–743.
https://doi.org/10.4049/jimmunol.179.2.740
Published: 15 July 2007
View article titled, Cutting Edge: Genetic Variation Influences FcεRI-Induced Mast Cell Activation and Allergic Responses
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Journal Articles

5-Hydroxytryptamine Induces Mast Cell Adhesion and Migration

Nataliya M. Kushnir-Sukhov, Alasdair M. Gilfillan, John W. Coleman, Jared M. Brown, Sandra Bruening, Miklos Toth, Dean D. Metcalfe
Journal: The Journal of Immunology
J Immunol (2006) 177 (9): 6422–6432.
https://doi.org/10.4049/jimmunol.177.9.6422
Published: 01 November 2006
View article titled, 5-Hydroxytryptamine Induces Mast Cell Adhesion and Migration
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Journal Articles

Cutting Edge: Lentiviral Short Hairpin RNA Silencing of PTEN in Human Mast Cells Reveals Constitutive Signals That Promote Cytokine Secretion and Cell Survival

Yasuko Furumoto, Steve Brooks, Ana Olivera, Yasuomi Takagi, Makoto Miyagishi, Kazunari Taira, Rafael Casellas, Michael A. Beaven, Alasdair M. Gilfillan, Juan Rivera
Journal: The Journal of Immunology
J Immunol (2006) 176 (9): 5167–5171.
https://doi.org/10.4049/jimmunol.176.9.5167
Published: 01 May 2006
View article titled, Cutting Edge: Lentiviral Short Hairpin RNA Silencing of PTEN in Human Mast Cells Reveals Constitutive Signals That Promote Cytokine Secretion and Cell Survival
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Journal Articles

Nitric Oxide Inhibits IgE-Dependent Cytokine Production and Fos and Jun Activation in Mast Cells

Beverley J. Davis, Brian F. Flanagan, Alasdair M. Gilfillan, Dean D. Metcalfe, John W. Coleman
Journal: The Journal of Immunology
J Immunol (2004) 173 (11): 6914–6920.
https://doi.org/10.4049/jimmunol.173.11.6914
Published: 01 December 2004
View article titled, Nitric Oxide Inhibits IgE-Dependent Cytokine Production and Fos and Jun Activation in Mast Cells
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Journal Articles

Induction of Telomerase Activity During Development of Human Mast Cells from Peripheral Blood CD34+ Cells: Comparisons with Tumor Mast-Cell Lines

Cristina Chaves-Dias, Thomas R. Hundley, Alasdair M. Gilfillan, Arnold S. Kirshenbaum, Jose Renan Cunha-Melo, Dean D. Metcalfe, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2001) 166 (11): 6647–6656.
https://doi.org/10.4049/jimmunol.166.11.6647
Published: 01 June 2001
View article titled, Induction of Telomerase Activity During Development of Human Mast Cells from Peripheral Blood CD34<sup>+</sup> Cells: Comparisons with Tumor Mast-Cell Lines
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