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Alessandro Moretta
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Journal Articles

Analysis of KIR3DP1 Polymorphism Provides Relevant Information on Centromeric KIR Gene Content

Maria Bono, Daniela Pende, Alice Bertaina, Alessandro Moretta, Mariella Della Chiesa, Simona Sivori, Marco Zecca, Franco Locatelli, Lorenzo Moretta, Cristina Bottino, Michela Falco
Journal: The Journal of Immunology
J Immunol (2018) 201 (5): 1460–1467.
https://doi.org/10.4049/jimmunol.1800564
Published: 01 September 2018
View article titled, Analysis of <em>KIR3DP1</em> Polymorphism Provides Relevant Information on Centromeric <em>KIR</em> Gene Content
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Includes: Supplementary data
Journal Articles

Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages

Francesca Bellora, Alessandra Dondero, Maria Valeria Corrias, Beatrice Casu, Stefano Regis, Fabio Caliendo, Alessandro Moretta, Mario Cazzola, Chiara Elena, Luciana Vinti, Franco Locatelli, Cristina Bottino, Roberta Castriconi
Journal: The Journal of Immunology
J Immunol (2017) 199 (4): 1516–1525.
https://doi.org/10.4049/jimmunol.1601695
Published: 15 August 2017
View article titled, Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages
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Includes: Supplementary data
Journal Articles

TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses

Rebecca E. Riise, Elin Bernson, Johan Aurelius, Anna Martner, Silvia Pesce, Mariella Della Chiesa, Emanuela Marcenaro, Johan Bylund, Kristoffer Hellstrand, Lorenzo Moretta, Alessandro Moretta, Fredrik B. Thorén
Journal: The Journal of Immunology
J Immunol (2015) 195 (3): 1121–1128.
https://doi.org/10.4049/jimmunol.1500709
Published: 01 August 2015
View article titled, TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses
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Includes: Supplementary data
Journal Articles

Human Cytomegalovirus Infection Promotes Rapid Maturation of NK Cells Expressing Activating Killer Ig–like Receptor in Patients Transplanted with NKG2C−/− Umbilical Cord Blood

Mariella Della Chiesa, Michela Falco, Alice Bertaina, Letizia Muccio, Claudia Alicata, Francesco Frassoni, Franco Locatelli, Lorenzo Moretta, Alessandro Moretta
Journal: The Journal of Immunology
J Immunol (2014) 192 (4): 1471–1479.
https://doi.org/10.4049/jimmunol.1302053
Published: 15 February 2014
View article titled, Human Cytomegalovirus Infection Promotes Rapid Maturation of NK Cells Expressing Activating Killer Ig–like Receptor in Patients Transplanted with NKG2C<sup>−/−</sup> Umbilical Cord Blood
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Includes: Supplementary data
Journal Articles

Neuroblastoma-Derived TGF-β1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells

Roberta Castriconi, Alessandra Dondero, Francesca Bellora, Lorenzo Moretta, Aurora Castellano, Franco Locatelli, Maria Valeria Corrias, Alessandro Moretta, Cristina Bottino
Journal: The Journal of Immunology
J Immunol (2013) 190 (10): 5321–5328.
https://doi.org/10.4049/jimmunol.1202693
Published: 15 May 2013
View article titled, Neuroblastoma-Derived TGF-β1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells
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Includes: Supplementary data
Journal Articles

Human NK Cells Selective Targeting of Colon Cancer–Initiating Cells: A Role for Natural Cytotoxicity Receptors and MHC Class I Molecules

Rossana Tallerico, Matilde Todaro, Simone Di Franco, Cristina Maccalli, Cinzia Garofalo, Rosa Sottile, Camillo Palmieri, Luca Tirinato, Pradeepa N. Pangigadde, Rosanna La Rocca, Ofer Mandelboim, Giorgio Stassi, Enzo Di Fabrizio, Giorgio Parmiani, Alessandro Moretta, Francesco Dieli, Klas Kärre, Ennio Carbone
Journal: The Journal of Immunology
J Immunol (2013) 190 (5): 2381–2390.
https://doi.org/10.4049/jimmunol.1201542
Published: 01 March 2013
View article titled, Human NK Cells Selective Targeting of Colon Cancer–Initiating Cells: A Role for Natural Cytotoxicity Receptors and MHC Class I Molecules
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Includes: Supplementary data
Journal Articles

Human NK Cells Induce Neutrophil Apoptosis via an NKp46- and Fas-Dependent Mechanism

Fredrik B. Thorén, Rebecca E. Riise, Jenny Ousbäck, Mariella Della Chiesa, Mikael Alsterholm, Emanuela Marcenaro, Silvia Pesce, Carola Prato, Claudia Cantoni, Johan Bylund, Lorenzo Moretta, Alessandro Moretta
Journal: The Journal of Immunology
J Immunol (2012) 188 (4): 1668–1674.
https://doi.org/10.4049/jimmunol.1102002
Published: 15 February 2012
View article titled, Human NK Cells Induce Neutrophil Apoptosis via an NKp46- and Fas-Dependent Mechanism
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Includes: Supplementary data
Journal Articles

Combined Genotypic and Phenotypic Killer Cell Ig-Like Receptor Analyses Reveal KIR2DL3 Alleles Displaying Unexpected Monoclonal Antibody Reactivity: Identification of the Amino Acid Residues Critical for Staining

Michela Falco, Elisa Romeo, Stefania Marcenaro, Stefania Martini, Massimo Vitale, Cristina Bottino, Maria Cristina Mingari, Lorenzo Moretta, Alessandro Moretta, Daniela Pende
Journal: The Journal of Immunology
J Immunol (2010) 185 (1): 433–441.
https://doi.org/10.4049/jimmunol.0903632
Published: 01 July 2010
View article titled, Combined Genotypic and Phenotypic Killer Cell Ig-Like Receptor Analyses Reveal KIR2DL3 Alleles Displaying Unexpected Monoclonal Antibody Reactivity: Identification of the Amino Acid Residues Critical for Staining
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Journal Articles

NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties

Roberta Castriconi, Antonio Daga, Alessandra Dondero, Gianluigi Zona, Pietro Luigi Poliani, Alice Melotti, Fabrizio Griffero, Daniela Marubbi, Renato Spaziante, Francesca Bellora, Lorenzo Moretta, Alessandro Moretta, Giorgio Corte, Cristina Bottino
Journal: The Journal of Immunology
J Immunol (2009) 182 (6): 3530–3539.
https://doi.org/10.4049/jimmunol.0802845
Published: 15 March 2009
View article titled, NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties
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Includes: Supplementary data
Journal Articles

CD56brightCD16− Killer Ig-Like Receptor− NK Cells Display Longer Telomeres and Acquire Features of CD56dim NK Cells upon Activation

Chiara Romagnani, Kerstin Juelke, Michela Falco, Barbara Morandi, Antonella D’Agostino, Roberta Costa, Giovanni Ratto, Giuseppe Forte, Paolo Carrega, Gabrielle Lui, Romana Conte, Till Strowig, Alessandro Moretta, Christian Münz, Andreas Thiel, Lorenzo Moretta, Guido Ferlazzo
Journal: The Journal of Immunology
J Immunol (2007) 178 (8): 4947–4955.
https://doi.org/10.4049/jimmunol.178.8.4947
Published: 15 April 2007
View article titled, CD56<sup>bright</sup>CD16<sup>−</sup> Killer Ig-Like Receptor<sup>−</sup> NK Cells Display Longer Telomeres and Acquire Features of CD56<sup>dim</sup> NK Cells upon Activation
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Journal Articles

NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection

Monia Draghi, Achal Pashine, Bharati Sanjanwala, Ketevan Gendzekhadze, Claudia Cantoni, David Cosman, Alessandro Moretta, Nicholas M. Valiante, Peter Parham
Journal: The Journal of Immunology
J Immunol (2007) 178 (5): 2688–2698.
https://doi.org/10.4049/jimmunol.178.5.2688
Published: 01 March 2007
View article titled, NKp46 and NKG2D Recognition of Infected Dendritic Cells Is Necessary for NK Cell Activation in the Human Response to Influenza Infection
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Journal Articles

The Inhibitory Receptor IRp60 (CD300a) Is Expressed and Functional on Human Mast Cells

Ido Bachelet, Ariel Munitz, Alessandro Moretta, Lorenzo Moretta, Francesca Levi-Schaffer
Journal: The Journal of Immunology
J Immunol (2005) 175 (12): 7989–7995.
https://doi.org/10.4049/jimmunol.175.12.7989
Published: 15 December 2005
View article titled, The Inhibitory Receptor IRp60 (CD300a) Is Expressed and Functional on Human Mast Cells
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Journal Articles

NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Receptors

Béatrice Le Maux Chansac, Alessandro Moretta, Isabelle Vergnon, Paule Opolon, Yann Lécluse, Dominique Grunenwald, Marek Kubin, Jean-Charles Soria, Salem Chouaib, Fathia Mami-Chouaib
Journal: The Journal of Immunology
J Immunol (2005) 175 (9): 5790–5798.
https://doi.org/10.4049/jimmunol.175.9.5790
Published: 01 November 2005
View article titled, NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Receptors
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Journal Articles

Distinctive Lack of CD48 Expression in Subsets of Human Dendritic Cells Tunes NK Cell Activation

Barbara Morandi, Roberta Costa, Michela Falco, Silvia Parolini, Andrea De Maria, Giovanni Ratto, Maria Cristina Mingari, Giovanni Melioli, Alessandro Moretta, Guido Ferlazzo
Journal: The Journal of Immunology
J Immunol (2005) 175 (6): 3690–3697.
https://doi.org/10.4049/jimmunol.175.6.3690
Published: 15 September 2005
View article titled, Distinctive Lack of CD48 Expression in Subsets of Human Dendritic Cells Tunes NK Cell Activation
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Journal Articles

Molecular and Functional Characterization of NKG2D, NKp80, and NKG2C Triggering NK Cell Receptors in Rhesus and Cynomolgus Macaques: Monitoring of NK Cell Function during Simian HIV Infection

Roberto Biassoni, Manuela Fogli, Claudia Cantoni, Paola Costa, Romana Conte, Gerrit Koopman, Aurelio Cafaro, Barbara Ensoli, Alessandro Moretta, Lorenzo Moretta, Andrea De Maria
Journal: The Journal of Immunology
J Immunol (2005) 174 (9): 5695–5705.
https://doi.org/10.4049/jimmunol.174.9.5695
Published: 01 May 2005
View article titled, Molecular and Functional Characterization of NKG2D, NKp80, and NKG2C Triggering NK Cell Receptors in Rhesus and Cynomolgus Macaques: Monitoring of NK Cell Function during Simian HIV Infection
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Journal Articles

IL-12 or IL-4 Prime Human NK Cells to Mediate Functionally Divergent Interactions with Dendritic Cells or Tumors

Emanuela Marcenaro, Mariella Della Chiesa, Francesca Bellora, Silvia Parolini, Romano Millo, Lorenzo Moretta, Alessandro Moretta
Journal: The Journal of Immunology
J Immunol (2005) 174 (7): 3992–3998.
https://doi.org/10.4049/jimmunol.174.7.3992
Published: 01 April 2005
View article titled, IL-12 or IL-4 Prime Human NK Cells to Mediate Functionally Divergent Interactions with Dendritic Cells or Tumors
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Journal Articles

The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic

Guido Ferlazzo, Dolca Thomas, Shao-Lee Lin, Kiera Goodman, Barbara Morandi, William A. Muller, Alessandro Moretta, Christian Münz
Journal: The Journal of Immunology
J Immunol (2004) 172 (3): 1455–1462.
https://doi.org/10.4049/jimmunol.172.3.1455
Published: 01 February 2004
View article titled, The Abundant NK Cells in Human Secondary Lymphoid Tissues Require Activation to Express Killer Cell Ig-Like Receptors and Become Cytolytic
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Journal Articles

Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements

Frédéric Vely, Marie-Alix Peyrat, Christelle Couedel, Jean-François Morcet, Franck Halary, François Davodeau, François Romagne, Emmanuel Scotet, Xavier Saulquin, Elisabeth Houssaint, Nicolas Schleinitz, Alessandro Moretta, Eric Vivier, Marc Bonneville
Journal: The Journal of Immunology
J Immunol (2001) 166 (4): 2487–2494.
https://doi.org/10.4049/jimmunol.166.4.2487
Published: 15 February 2001
View article titled, Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements
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Journal Articles

Human T Lymphocyte Subpopulations: Studies of the Mechanism by Which T Cells Bearing Fc Receptors for IgG Suppress T-Dependent B Cell Differentiation Induced by Pokeweed Mitogen

Lorenzo Moretta, Maria Cristina Mingari, Alessandro Moretta, Max D. Cooper
Journal: The Journal of Immunology
J Immunol (1979) 122 (3): 984–990.
https://doi.org/10.4049/jimmunol.122.3.984
Published: 01 March 1979
View article titled, Human T Lymphocyte Subpopulations: Studies of the Mechanism by Which T Cells Bearing Fc Receptors for IgG Suppress T-Dependent B Cell Differentiation Induced by Pokeweed Mitogen
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Journal Articles

Fc-Receptors for IgG and IgM Immunoglobulins on Human T Lymphocytes: Mode of Re-Expression after Proteolysis or Interaction with Immune Complexes

Maria Cristina Mingari, Lorenzo Moretta, Alessandro Moretta, Manlio Ferrarini, Jean Louis Preud'Homme
Journal: The Journal of Immunology
J Immunol (1978) 121 (2): 767–770.
https://doi.org/10.4049/jimmunol.121.2.767
Published: 01 August 1978
View article titled, Fc-Receptors for IgG and IgM Immunoglobulins on Human T Lymphocytes: Mode of Re-Expression after Proteolysis or Interaction with Immune Complexes
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