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Alexander H. Dalpke
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Journal Articles

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism

Dominik Stammler, Tatjana Eigenbrod, Sarah Menz, Julia S. Frick, Matthew J. Sweet, Melanie R. Shakespear, Jonathan Jantsch, Isabel Siegert, Sabine Wölfle, Julian D. Langer, Ina Oehme, Liliana Schaefer, Andre Fischer, Judith Knievel, Klaus Heeg, Alexander H. Dalpke, Konrad A. Bode
Journal: The Journal of Immunology
J Immunol (2015) 195 (11): 5421–5431.
https://doi.org/10.4049/jimmunol.1501195
Published: 01 December 2015
View article titled, Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism
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Includes: Supplementary data
Journal Articles

TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes

Tatjana Eigenbrod, Karin Pelka, Eicke Latz, Bernd Kreikemeyer, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2015) 195 (3): 1092–1099.
https://doi.org/10.4049/jimmunol.1403173
Published: 01 August 2015
View article titled, TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of <em>Streptococcus pyogenes</em>
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Includes: Supplementary data
Journal Articles

Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses

In Special Collection:
Brief Reviews
Tatjana Eigenbrod, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2015) 195 (2): 411–418.
https://doi.org/10.4049/jimmunol.1500530
Published: 15 July 2015
View article titled, Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses
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Journal Articles

Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling

Michael Weitnauer, Lotte Schmidt, Nathalie Ng Kuet Leong, Stephanie Muenchau, Felix Lasitschka, Volker Eckstein, Sabine Hübner, Jan Tuckermann, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2014) 193 (3): 1475–1484.
https://doi.org/10.4049/jimmunol.1400446
Published: 01 August 2014
View article titled, Bronchial Epithelial Cells Induce Alternatively Activated Dendritic Cells Dependent on Glucocorticoid Receptor Signaling
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Journal Articles

Early Inhibition of IL-1β Expression by IFN-γ Is Mediated by Impaired Binding of NF-κB to the IL-1β Promoter but Is Independent of Nitric Oxide

Tatjana Eigenbrod, Konrad A. Bode, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2013) 190 (12): 6533–6541.
https://doi.org/10.4049/jimmunol.1300324
Published: 15 June 2013
View article titled, Early Inhibition of IL-1β Expression by IFN-γ Is Mediated by Impaired Binding of NF-κB to the IL-1β Promoter but Is Independent of Nitric Oxide
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Journal Articles

Cutting Edge: TLR13 Is a Receptor for Bacterial RNA

Asa Hidmark, Antonia von Saint Paul, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 2717–2721.
https://doi.org/10.4049/jimmunol.1200898
Published: 15 September 2012
View article titled, Cutting Edge: TLR13 Is a Receptor for Bacterial RNA
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Includes: Supplementary data
Journal Articles

Dectin-1 Stimulation Induces Suppressor of Cytokine Signaling 1, Thereby Modulating TLR Signaling and T Cell Responses

Mariel E. Eberle, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5644–5654.
https://doi.org/10.4049/jimmunol.1103068
Published: 01 June 2012
View article titled, Dectin-1 Stimulation Induces Suppressor of Cytokine Signaling 1, Thereby Modulating TLR Signaling and T Cell Responses
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Includes: Supplementary data
Journal Articles

Bronchial Epithelial Cell-Derived Prostaglandin E2 Dampens the Reactivity of Dendritic Cells

Lotte M. Schmidt, Maria G. Belvisi, Konrad A. Bode, Judith Bauer, Claudia Schmidt, Maria-Theresia Suchy, Dimitrios Tsikas, Jutta Scheuerer, Felix Lasitschka, Herman-Josef Gröne, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2011) 186 (4): 2095–2105.
https://doi.org/10.4049/jimmunol.1002414
Published: 15 February 2011
View article titled, Bronchial Epithelial Cell-Derived Prostaglandin E<sub>2</sub> Dampens the Reactivity of Dendritic Cells
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Journal Articles

Identification of an N-Terminal Recognition Site in TLR9 That Contributes to CpG-DNA-Mediated Receptor Activation

Mirjam E. Peter, Andriy V. Kubarenko, Alexander N. R. Weber, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2009) 182 (12): 7690–7697.
https://doi.org/10.4049/jimmunol.0900819
Published: 15 June 2009
View article titled, Identification of an N-Terminal Recognition Site in TLR9 That Contributes to CpG-DNA-Mediated Receptor Activation
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Journal Articles

Kinetic of RelA Activation Controls Magnitude of TLR-Mediated IL-12p40 Induction

Konrad A. Bode, Frank Schmitz, Leonardo Vargas, Klaus Heeg, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2009) 182 (4): 2176–2184.
https://doi.org/10.4049/jimmunol.0802560
Published: 15 February 2009
View article titled, Kinetic of RelA Activation Controls Magnitude of TLR-Mediated IL-12p40 Induction
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Journal Articles

Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference

Florian Eberle, Kerstin Gießler, Christopher Deck, Klaus Heeg, Mirjam Peter, Clemens Richert, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 3229–3237.
https://doi.org/10.4049/jimmunol.180.5.3229
Published: 01 March 2008
View article titled, Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference
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Journal Articles

Differential Effects of CpG DNA on IFN-β Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages

Kate Schroder, Martina Spille, Andreas Pilz, Jane Lattin, Konrad A. Bode, Katharine M. Irvine, Allan D. Burrows, Timothy Ravasi, Heike Weighardt, Katryn J. Stacey, Thomas Decker, David A. Hume, Alexander H. Dalpke, Matthew J. Sweet
Journal: The Journal of Immunology
J Immunol (2007) 179 (6): 3495–3503.
https://doi.org/10.4049/jimmunol.179.6.3495
Published: 15 September 2007
View article titled, Differential Effects of CpG DNA on IFN-β Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages
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Journal Articles

Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells

Anja K. Mayer, Mario Muehmer, Jörg Mages, Katja Gueinzius, Christian Hess, Klaus Heeg, Robert Bals, Roland Lang, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2007) 178 (5): 3134–3142.
https://doi.org/10.4049/jimmunol.178.5.3134
Published: 01 March 2007
View article titled, Differential Recognition of TLR-Dependent Microbial Ligands in Human Bronchial Epithelial Cells
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Includes: Supplementary data
Journal Articles

Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-γ Signaling

Stefan Zimmermann, Peter J. Murray, Klaus Heeg, Alexander H. Dalpke
Journal: The Journal of Immunology
J Immunol (2006) 176 (3): 1840–1847.
https://doi.org/10.4049/jimmunol.176.3.1840
Published: 01 February 2006
View article titled, Induction of Suppressor of Cytokine Signaling-1 by <em>Toxoplasma gondii</em> Contributes to Immune Evasion in Macrophages by Blocking IFN-γ Signaling
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Journal Articles

Immunostimulatory CpG-DNA Activates Murine Microglia

Alexander H. Dalpke, Martin K.-H. Schäfer, Markus Frey, Stefan Zimmermann, Johannes Tebbe, Eberhard Weihe, Klaus Heeg
Journal: The Journal of Immunology
J Immunol (2002) 168 (10): 4854–4863.
https://doi.org/10.4049/jimmunol.168.10.4854
Published: 15 May 2002
View article titled, Immunostimulatory CpG-DNA Activates Murine Microglia
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Journal Articles

Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs

Alexander H. Dalpke, Sandra Opper, Stefan Zimmermann, Klaus Heeg
Journal: The Journal of Immunology
J Immunol (2001) 166 (12): 7082–7089.
https://doi.org/10.4049/jimmunol.166.12.7082
Published: 15 June 2001
View article titled, Suppressors of Cytokine Signaling (SOCS)-1 and SOCS-3 Are Induced by CpG-DNA and Modulate Cytokine Responses in APCs
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