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Alexander Steinle
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Journal Articles

Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80

Sebastian Neuss, Yvonne Bartel, Christina Born, Sandra Weil, Joachim Koch, Christian Behrends, Meike Hoffmeister, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2018) 201 (4): 1275–1286.
https://doi.org/10.4049/jimmunol.1800059
Published: 15 August 2018
View article titled, Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80
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Journal Articles

Pillars Article: Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA. Science. 1999. 285: 727–729

Stefan Bauer, Veronika Groh, Jun Wu, Alexander Steinle, Joseph H. Phillips, Lewis L. Lanier, Thomas Spies
Journal: The Journal of Immunology
J Immunol (2018) 200 (7): 2231–2233.
Published: 01 April 2018
View article titled, Pillars Article: Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICA. <em>Science</em>. 1999. 285: 727–729
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Journal Articles

Select Clr-g Expression on Activated Dendritic Cells Facilitates Cognate Interaction with a Minor Subset of Splenic NK Cells Expressing the Inhibitory Nkrp1g Receptor

Miriam E. Friede, Stefan Leibelt, Diana Dudziak, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2018) 200 (3): 983–996.
https://doi.org/10.4049/jimmunol.1701180
Published: 01 February 2018
View article titled, Select Clr-g Expression on Activated Dendritic Cells Facilitates Cognate Interaction with a Minor Subset of Splenic NK Cells Expressing the Inhibitory Nkrp1g Receptor
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Includes: Supplementary data
Journal Articles

Clr-a: A Novel Immune-Related C-Type Lectin-like Molecule Exclusively Expressed by Mouse Gut Epithelium

Emilia Rutkowski, Stefan Leibelt, Christina Born, Miriam E. Friede, Stefan Bauer, Sandra Weil, Joachim Koch, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2017) 198 (2): 916–926.
https://doi.org/10.4049/jimmunol.1600666
Published: 15 January 2017
View article titled, Clr-a: A Novel Immune-Related C-Type Lectin-like Molecule Exclusively Expressed by Mouse Gut Epithelium
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Includes: Supplementary data
Journal Articles

Fc-Optimized NKG2D–Fc Constructs Induce NK Cell Antibody-Dependent Cellular Cytotoxicity against Breast Cancer Cells Independently of HER2/neu Expression Status

Stefanie Raab, Julia Steinbacher, Benjamin J. Schmiedel, Philaretos C. Kousis, Alexander Steinle, Gundram Jung, Ludger Grosse-Hovest, Helmut R. Salih
Journal: The Journal of Immunology
J Immunol (2014) 193 (8): 4261–4272.
https://doi.org/10.4049/jimmunol.1400872
Published: 15 October 2014
View article titled, Fc-Optimized NKG2D–Fc Constructs Induce NK Cell Antibody-Dependent Cellular Cytotoxicity against Breast Cancer Cells Independently of HER2/neu Expression Status
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Includes: Supplementary data
Journal Articles

Altered MicroRNA Expression after Infection with Human Cytomegalovirus Leads to TIMP3 Downregulation and Increased Shedding of Metalloprotease Substrates, Including MICA

Gloria Esteso, Elisa Luzón, Elisabeth Sarmiento, Ruth Gómez-Caro, Alexander Steinle, Gillian Murphy, Javier Carbone, Mar Valés-Gómez, Hugh T. Reyburn
Journal: The Journal of Immunology
J Immunol (2014) 193 (3): 1344–1352.
https://doi.org/10.4049/jimmunol.1303441
Published: 01 August 2014
View article titled, Altered MicroRNA Expression after Infection with Human Cytomegalovirus Leads to TIMP3 Downregulation and Increased Shedding of Metalloprotease Substrates, Including MICA
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Includes: Supplementary data
Journal Articles

NKp65 hallmarks a rare subset of human innate lymphocytes (P4347)

Alexander Steinle, Claudia Döring, Martin-Leo Hansmann, Isabel Vogler
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 183.9.
https://doi.org/10.4049/jimmunol.190.Supp.183.9
Published: 01 May 2013
View article titled, NKp65 hallmarks a rare subset of human innate lymphocytes (P4347)
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Comprehensive Analysis of NKG2D Ligand Expression and Release in Leukemia: Implications for NKG2D-Mediated NK Cell Responses

Julia Hilpert, Ludger Grosse-Hovest, Frank Grünebach, Corina Buechele, Tina Nuebling, Tobias Raum, Alexander Steinle, Helmut Rainer Salih
Journal: The Journal of Immunology
J Immunol (2012) 189 (3): 1360–1371.
https://doi.org/10.4049/jimmunol.1200796
Published: 01 August 2012
View article titled, Comprehensive Analysis of NKG2D Ligand Expression and Release in Leukemia: Implications for NKG2D-Mediated NK Cell Responses
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Includes: Supplementary data
Journal Articles

Cutting Edge: NKp80 Uses an Atypical Hemi-ITAM To Trigger NK Cytotoxicity

Kevin M. Dennehy, Sascha N. Klimosch, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2011) 186 (2): 657–661.
https://doi.org/10.4049/jimmunol.0904117
Published: 15 January 2011
View article titled, Cutting Edge: NKp80 Uses an Atypical Hemi-ITAM To Trigger NK Cytotoxicity
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Journal Articles

Conserved Amino Acids within the Adenovirus 2 E3/19K Protein Differentially Affect Downregulation of MHC Class I and MICA/B Proteins

Martina Sester, Katja Koebernick, Douglas Owen, Minghui Ao, Yana Bromberg, Ed May, Emily Stock, Lawrence Andrews, Veronika Groh, Thomas Spies, Alexander Steinle, Beatrice Menz, Hans-Gerhard Burgert
Journal: The Journal of Immunology
J Immunol (2010) 184 (1): 255–267.
https://doi.org/10.4049/jimmunol.0902343
Published: 14 December 2009
View article titled, Conserved Amino Acids within the Adenovirus 2 E3/19K Protein Differentially Affect Downregulation of MHC Class I and MICA/B Proteins
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Journal Articles

NKG2D-mediated activation of NK cells by allogeneic CD34+ blood cells. (141.9)

Mario Arpinati, Benedetta Nicolini, Alexander Steinle, Damiano Rondelli
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 141.9.
https://doi.org/10.4049/jimmunol.182.Supp.141.9
Published: 01 April 2009
View article titled, NKG2D-mediated activation of NK cells by allogeneic CD34+ blood cells. (141.9)
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Journal Articles

CLEC2A Is a Novel Skin-Specific, Stimulatory Ligand of Human NK Cells (39.8)

Alexander Steinle, Veronika Stejfova, Sabrina Kuttruff, Birgit Schittek, Jessica Spreu
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 39.8.
https://doi.org/10.4049/jimmunol.182.Supp.39.8
Published: 01 April 2009
View article titled, CLEC2A Is a Novel Skin-Specific, Stimulatory Ligand of Human NK Cells (39.8)
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Journal Articles

Interaction of Monocytes with NK Cells upon Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA

Mercedes Kloss, Patrice Decker, Katrin M. Baltz, Tina Baessler, Gundram Jung, Hans-Georg Rammensee, Alexander Steinle, Matthias Krusch, Helmut R. Salih
Journal: The Journal of Immunology
J Immunol (2008) 181 (10): 6711–6719.
https://doi.org/10.4049/jimmunol.181.10.6711
Published: 15 November 2008
View article titled, Interaction of Monocytes with NK Cells upon Toll-Like Receptor-Induced Expression of the NKG2D Ligand MICA
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Journal Articles

Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D

Mathias Krockenberger, Yvonne Dombrowski, Claudia Weidler, Monika Ossadnik, Arnd Hönig, Sebastian Häusler, Heike Voigt, Jürgen C. Becker, Lin Leng, Alexander Steinle, Michael Weller, Richard Bucala, Johannes Dietl, Jörg Wischhusen
Journal: The Journal of Immunology
J Immunol (2008) 180 (11): 7338–7348.
https://doi.org/10.4049/jimmunol.180.11.7338
Published: 01 June 2008
View article titled, Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D
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Journal Articles

Human Cytomegalovirus-Encoded UL16 Discriminates MIC Molecules by Their α2 Domains

Jessica Spreu, Thilo Stehle, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 3143–3149.
https://doi.org/10.4049/jimmunol.177.5.3143
Published: 01 September 2006
View article titled, Human Cytomegalovirus-Encoded UL16 Discriminates MIC Molecules by Their α2 Domains
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Journal Articles

BCR/ABL Oncogene Directly Controls MHC Class I Chain-Related Molecule A Expression in Chronic Myelogenous Leukemia

Nicolas Boissel, Delphine Rea, Vannary Tieng, Nicolas Dulphy, Manuel Brun, Jean-Michel Cayuela, Philippe Rousselot, Ryad Tamouza, Philippe Le Bouteiller, François-Xavier Mahon, Alexander Steinle, Dominique Charron, Hervé Dombret, Antoine Toubert
Journal: The Journal of Immunology
J Immunol (2006) 176 (8): 5108–5116.
https://doi.org/10.4049/jimmunol.176.8.5108
Published: 15 April 2006
View article titled, BCR/ABL Oncogene Directly Controls MHC Class I Chain-Related Molecule A Expression in Chronic Myelogenous Leukemia
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Journal Articles

Activation of Vγ9Vδ2 T Cells by NKG2D

Bladimiro Rincon-Orozco, Volker Kunzmann, Philine Wrobel, Dieter Kabelitz, Alexander Steinle, Thomas Herrmann
Journal: The Journal of Immunology
J Immunol (2005) 175 (4): 2144–2151.
https://doi.org/10.4049/jimmunol.175.4.2144
Published: 15 August 2005
View article titled, Activation of Vγ9Vδ2 T Cells by NKG2D
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Journal Articles

Systemic NKG2D Down-Regulation Impairs NK and CD8 T Cell Responses In Vivo

Katrin Wiemann, Hans-Willi Mittrücker, Ute Feger, Stefan A. Welte, Wayne M. Yokoyama, Thomas Spies, Hans-Georg Rammensee, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2005) 175 (2): 720–729.
https://doi.org/10.4049/jimmunol.175.2.720
Published: 15 July 2005
View article titled, Systemic NKG2D Down-Regulation Impairs NK and CD8 T Cell Responses In Vivo
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Journal Articles

Cutting Edge: Down-Regulation of MICA on Human Tumors by Proteolytic Shedding

Helmut R. Salih, Hans-Georg Rammensee, Alexander Steinle
Journal: The Journal of Immunology
J Immunol (2002) 169 (8): 4098–4102.
https://doi.org/10.4049/jimmunol.169.8.4098
Published: 15 October 2002
View article titled, Cutting Edge: Down-Regulation of MICA on Human Tumors by Proteolytic Shedding
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