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Allen W. Cheever
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Journal Articles

Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections

Mark S. Wilson, Carl G. Feng, Daniel L. Barber, Felix Yarovinsky, Allen W. Cheever, Alan Sher, Michael Grigg, Mary Collins, Lynette Fouser, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2010) 184 (8): 4378–4390.
https://doi.org/10.4049/jimmunol.0903416
Published: 15 April 2010
View articletitled, Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections
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Includes: Supplementary data
Journal Articles

Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13–Dependent Fibrosis

Satish K. Madala, John T. Pesce, Thirumalai R. Ramalingam, Mark S. Wilson, Samantha Minnicozzi, Allen W. Cheever, Robert W. Thompson, Margaret M. Mentink-Kane, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3955–3963.
https://doi.org/10.4049/jimmunol.0903008
Published: 01 April 2010
View articletitled, Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13–Dependent Fibrosis
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Includes: Supplementary data
Journal Articles

Regulation of Helminth-Induced Th2 Responses by Thymic Stromal Lymphopoietin

Thirumalai R. Ramalingam, John T. Pesce, Margaret M. Mentink-Kane, Satish Madala, Allen W. Cheever, Michael R. Comeau, Steven F. Ziegler, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2009) 182 (10): 6452–6459.
https://doi.org/10.4049/jimmunol.0900181
Published: 15 May 2009
View articletitled, Regulation of Helminth-Induced Th2 Responses by Thymic Stromal Lymphopoietin
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Journal Articles

CD103-expressing CD4+Foxp3+ regulatory T cells are critical for the survival of mice infected with the helminth parasite Schistosoma mansoni. (46.17)

Matthias Hesse, Mark S. Wilson, Allen W. Cheever, Thomas A. Wynn, Siddhartha Bajracharya
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S64.
https://doi.org/10.4049/jimmunol.178.Supp.46.17
Published: 01 April 2007
View articletitled, CD103-expressing CD4+Foxp3+ regulatory T cells are critical for the survival of mice infected with the helminth parasite Schistosoma mansoni. (46.17)
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Journal Articles

IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent

Mallika Kaviratne, Matthias Hesse, Mary Leusink, Allen W. Cheever, Stephen J. Davies, James H. McKerrow, Lalage M. Wakefield, John J. Letterio, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2004) 173 (6): 4020–4029.
https://doi.org/10.4049/jimmunol.173.6.4020
Published: 15 September 2004
View articletitled, IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent
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Journal Articles

The Pathogenesis of Schistosomiasis Is Controlled by Cooperating IL-10-Producing Innate Effector and Regulatory T Cells

Matthias Hesse, Ciriaco A. Piccirillo, Yasmine Belkaid, Jeannette Prufer, Margaret Mentink-Kane, Mary Leusink, Allen W. Cheever, Ethan M. Shevach, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2004) 172 (5): 3157–3166.
https://doi.org/10.4049/jimmunol.172.5.3157
Published: 01 March 2004
View articletitled, The Pathogenesis of Schistosomiasis Is Controlled by Cooperating IL-10-Producing Innate Effector and Regulatory T Cells
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Journal Articles

Mice Lacking Myeloid Differentiation Factor 88 Display Profound Defects in Host Resistance and Immune Responses to Mycobacterium avium Infection Not Exhibited by Toll-Like Receptor 2 (TLR2)- and TLR4-Deficient Animals

Carl G. Feng, Charles A. Scanga, Carmen M. Collazo-Custodio, Allen W. Cheever, Sara Hieny, Patricia Caspar, Alan Sher
Journal: The Journal of Immunology
J Immunol (2003) 171 (9): 4758–4764.
https://doi.org/10.4049/jimmunol.171.9.4758
Published: 01 November 2003
View articletitled, Mice Lacking Myeloid Differentiation Factor 88 Display Profound Defects in Host Resistance and Immune Responses to Mycobacterium avium Infection Not Exhibited by Toll-Like Receptor 2 (TLR2)- and TLR4-Deficient Animals
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Journal Articles

Global Gene Expression Profiles During Acute Pathogen-Induced Pulmonary Inflammation Reveal Divergent Roles for Th1 and Th2 Responses in Tissue Repair

Netanya G. Sandler, Margaret M. Mentink-Kane, Allen W. Cheever, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2003) 171 (7): 3655–3667.
https://doi.org/10.4049/jimmunol.171.7.3655
Published: 01 October 2003
View articletitled, Global Gene Expression Profiles During Acute Pathogen-Induced Pulmonary Inflammation Reveal Divergent Roles for Th1 and Th2 Responses in Tissue Repair
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Journal Articles

IL-10 Is Critical for Host Resistance and Survival During Gastrointestinal Helminth Infection

Lisa R. Schopf, Karl F. Hoffmann, Allen W. Cheever, Joseph F. Urban, Jr., Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2002) 168 (5): 2383–2392.
https://doi.org/10.4049/jimmunol.168.5.2383
Published: 01 March 2002
View articletitled, IL-10 Is Critical for Host Resistance and Survival During Gastrointestinal Helminth Infection
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Journal Articles

Regulation of Hepatic Fibrosis and Extracellular Matrix Genes by the Th Response: New Insight into the Role of Tissue Inhibitors of Matrix Metalloproteinases

Brian Vaillant, Monica G. Chiaramonte, Allen W. Cheever, Paul D. Soloway, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2001) 167 (12): 7017–7026.
https://doi.org/10.4049/jimmunol.167.12.7017
Published: 15 December 2001
View articletitled, Regulation of Hepatic Fibrosis and Extracellular Matrix Genes by the Th Response: New Insight into the Role of Tissue Inhibitors of Matrix Metalloproteinases
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Journal Articles

Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of l-Arginine Metabolism1

Matthias Hesse, Manuel Modolell, Anne C. La Flamme, Marco Schito, José Manuel Fuentes, Allen W. Cheever, Edward J. Pearce, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2001) 167 (11): 6533–6544.
https://doi.org/10.4049/jimmunol.167.11.6533
Published: 01 December 2001
View articletitled, Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of l-Arginine Metabolism1
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Journal Articles

Testing Time-, Ignorance-, and Danger-Based Models of Tolerance

Colin C. Anderson, Joseph M. Carroll, Stefania Gallucci, John P. Ridge, Allen W. Cheever, Polly Matzinger
Journal: The Journal of Immunology
J Immunol (2001) 166 (6): 3663–3671.
https://doi.org/10.4049/jimmunol.166.6.3663
Published: 15 March 2001
View articletitled, Testing Time-, Ignorance-, and Danger-Based Models of Tolerance
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Journal Articles

IL-10 and the Dangers of Immune Polarization: Excessive Type 1 and Type 2 Cytokine Responses Induce Distinct Forms of Lethal Immunopathology in Murine Schistosomiasis

Karl F. Hoffmann, Allen W. Cheever, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2000) 164 (12): 6406–6416.
https://doi.org/10.4049/jimmunol.164.12.6406
Published: 15 June 2000
View articletitled, IL-10 and the Dangers of Immune Polarization: Excessive Type 1 and Type 2 Cytokine Responses Induce Distinct Forms of Lethal Immunopathology in Murine Schistosomiasis
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Journal Articles

CpG Oligonucleotides Can Prophylactically Immunize Against Th2-Mediated Schistosome Egg-Induced Pathology by an IL-12-Independent Mechanism

Mónica G. Chiaramonte, Matthias Hesse, Allen W. Cheever, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (2000) 164 (2): 973–985.
https://doi.org/10.4049/jimmunol.164.2.973
Published: 15 January 2000
View articletitled, CpG Oligonucleotides Can Prophylactically Immunize Against Th2-Mediated Schistosome Egg-Induced Pathology by an IL-12-Independent Mechanism
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Journal Articles

Studies with Double Cytokine-Deficient Mice Reveal That Highly Polarized Th1- and Th2-Type Cytokine and Antibody Responses Contribute Equally to Vaccine-Induced Immunity to Schistosoma mansoni

Karl F. Hoffmann, Stephanie L. James, Allen W. Cheever, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (1999) 163 (2): 927–938.
https://doi.org/10.4049/jimmunol.163.2.927
Published: 15 July 1999
View articletitled, Studies with Double Cytokine-Deficient Mice Reveal That Highly Polarized Th1- and Th2-Type Cytokine and Antibody Responses Contribute Equally to Vaccine-Induced Immunity to Schistosoma mansoni
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Journal Articles

Schistosome-Infected IL-4 Receptor Knockout (KO) Mice, in Contrast to IL-4 KO Mice, Fail to Develop Granulomatous Pathology While Maintaining the Same Lymphokine Expression Profile

Dragana Jankovic, Marika C. Kullberg, Nancy Noben-Trauth, Patricia Caspar, Jerrold M. Ward, Allen W. Cheever, William E. Paul, Alan Sher
Journal: The Journal of Immunology
J Immunol (1999) 163 (1): 337–342.
https://doi.org/10.4049/jimmunol.163.1.337
Published: 01 July 1999
View articletitled, Schistosome-Infected IL-4 Receptor Knockout (KO) Mice, in Contrast to IL-4 KO Mice, Fail to Develop Granulomatous Pathology While Maintaining the Same Lymphokine Expression Profile
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Journal Articles

IL-13 Is a Key Regulatory Cytokine for Th2 Cell-Mediated Pulmonary Granuloma Formation and IgE Responses Induced by Schistosoma mansoni Eggs

Mónica G. Chiaramonte, Lisa R. Schopf, Tamlyn Y. Neben, Allen W. Cheever, Debra D. Donaldson, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (1999) 162 (2): 920–930.
https://doi.org/10.4049/jimmunol.162.2.920
Published: 15 January 1999
View articletitled, IL-13 Is a Key Regulatory Cytokine for Th2 Cell-Mediated Pulmonary Granuloma Formation and IgE Responses Induced by Schistosoma mansoni Eggs
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Journal Articles

Optimal Vaccination Against Schistosoma mansoni Requires the Induction of Both B Cell- and IFN-γ-Dependent Effector Mechanisms

Dragana Jankovic, Thomas A. Wynn, Marika C. Kullberg, Sara Hieny, Patricia Caspar, Stephanie James, Allen W. Cheever, Alan Sher
Journal: The Journal of Immunology
J Immunol (1999) 162 (1): 345–351.
https://doi.org/10.4049/jimmunol.162.1.345
Published: 01 January 1999
View articletitled, Optimal Vaccination Against Schistosoma mansoni Requires the Induction of Both B Cell- and IFN-γ-Dependent Effector Mechanisms
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Journal Articles

IFN-γ, IL-12, and TNF-α Are Required to Maintain Reduced Liver Pathology in Mice Vaccinated with Schistosoma mansoni Eggs and IL-12

Karl F. Hoffmann, Pat Caspar, Allen W. Cheever, Thomas A. Wynn
Journal: The Journal of Immunology
J Immunol (1998) 161 (8): 4201–4210.
https://doi.org/10.4049/jimmunol.161.8.4201
Published: 15 October 1998
View articletitled, IFN-γ, IL-12, and TNF-α Are Required to Maintain Reduced Liver Pathology in Mice Vaccinated with Schistosoma mansoni Eggs and IL-12
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Journal Articles

IL-10 Regulates Liver Pathology in Acute Murine Schistosomiasis mansoni But Is Not Required for Immune Down-Modulation of Chronic Disease

Thomas A. Wynn, Allen W. Cheever, Megan E. Williams, Sara Hieny, Pat Caspar, Ralf Kühn, Werner Müller, Alan Sher
Journal: The Journal of Immunology
J Immunol (1998) 160 (9): 4473–4480.
https://doi.org/10.4049/jimmunol.160.9.4473
Published: 01 May 1998
View articletitled, IL-10 Regulates Liver Pathology in Acute Murine Schistosomiasis mansoni But Is Not Required for Immune Down-Modulation of Chronic Disease
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