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Andrea Amalfitano
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Journal Articles

Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis

Free
Patrick O’Connell, Maja K. Blake, Sarah Godbehere, Yasser A. Aldhamen, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2021) 207 (12): 2952–2965.
https://doi.org/10.4049/jimmunol.2100813
Published: 15 December 2021
View articletitled, Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis
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Includes: Supplementary data
Journal Articles

SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment

Free
Patrick O’Connell, Sean Hyslop, Maja K. Blake, Sarah Godbehere, Andrea Amalfitano, Yasser A. Aldhamen
Journal: The Journal of Immunology
J Immunol (2021) 206 (1): 193–205.
https://doi.org/10.4049/jimmunol.2000300
Published: 01 January 2021
View articletitled, SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

SLAMF7 Is a Critical Negative Regulator of IFN-α–Mediated CXCL10 Production in Chronic HIV Infection

Free
Patrick O’Connell, Yuliya Pepelyayeva, Maja K. Blake, Sean Hyslop, Robert B. Crawford, Michael D. Rizzo, Cristiane Pereira-Hicks, Sarah Godbehere, Linda Dale, Peter Gulick, Norbert E. Kaminski, Andrea Amalfitano, Yasser A. Aldhamen
Journal: The Journal of Immunology
J Immunol (2019) 202 (1): 228–238.
https://doi.org/10.4049/jimmunol.1800847
Published: 01 January 2019
View articletitled, SLAMF7 Is a Critical Negative Regulator of IFN-α–Mediated CXCL10 Production in Chronic HIV Infection
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Includes: Supplementary data
Journal Articles

Endoplasmic Reticulum Aminopeptidase I-driven Production of IL-18 and IL-1β Protects from Severe Intestinal Inflammation and Mortality during Experimental Colitis

Free
Yasser Ali Aldhamen, Fadel S Alyaqoub, Yuliya Pepelyayeva, David P.W. Rastall, Ashley Raedy, Patrick O’Connell, Cristiane Pereira-Hicks, Sarah Godbehere, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 207.1.
https://doi.org/10.4049/jimmunol.196.Supp.207.1
Published: 01 May 2016
View articletitled, Endoplasmic Reticulum Aminopeptidase I-driven Production of IL-18 and IL-1β Protects from Severe Intestinal Inflammation and Mortality during Experimental Colitis
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Journal Articles

In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens

Free
Fadel S. Alyaqoub, Yasser A. Aldhamen, Benjamin J. Koestler, Eric L. Bruger, Sergey S. Seregin, Cristiane Pereira-Hicks, Sarah Godbehere, Christopher M. Waters, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2016) 196 (4): 1741–1752.
https://doi.org/10.4049/jimmunol.1501272
Published: 15 February 2016
View articletitled, In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens
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Includes: Supplementary data
Journal Articles

A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing

Free
Irini Evnouchidou, James Birtley, Sergey Seregin, Athanasios Papakyriakou, Efthalia Zervoudi, Martina Samiotaki, George Panayotou, Petros Giastas, Olivia Petrakis, Dimitris Georgiadis, Andrea Amalfitano, Emmanuel Saridakis, Irene M. Mavridis, Efstratios Stratikos
Journal: The Journal of Immunology
J Immunol (2012) 189 (5): 2383–2392.
https://doi.org/10.4049/jimmunol.1200918
Published: 01 September 2012
View articletitled, A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen Processing
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Includes: Supplementary data
Journal Articles

Vaccines Expressing the Innate Immune Modulator EAT-2 Elicit Potent Effector Memory T Lymphocyte Responses despite Pre-Existing Vaccine Immunity

Free
Yasser Ali Aldhamen, Sergey S. Seregin, Nathaniel J. Schuldt, David P. W. Rastall, Chyong-jy J. Liu, Sarah Godbehere, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2012) 189 (3): 1349–1359.
https://doi.org/10.4049/jimmunol.1200736
Published: 01 August 2012
View articletitled, Vaccines Expressing the Innate Immune Modulator EAT-2 Elicit Potent Effector Memory T Lymphocyte Responses despite Pre-Existing Vaccine Immunity
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Includes: Supplementary data
Journal Articles

Overexpression of EAT-2, a SLAM family receptor adaptor molecule, suppresses CRACC receptor expression on Antigen Presenting Cells in an ERK MAP kinase dependent mechanism (110.26)

Free
Yasser Aldhamen, Sergey Seregin, Chyong-jy Liu, Charles Aylsworth, Sarah Godbehere, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 110.26.
https://doi.org/10.4049/jimmunol.186.Supp.110.26
Published: 01 April 2011
View articletitled, Overexpression of EAT-2, a SLAM family receptor adaptor molecule, suppresses CRACC receptor expression on Antigen Presenting Cells in an ERK MAP kinase dependent mechanism (110.26)
Add to Citation Manager for Overexpression of EAT-2, a SLAM family receptor adaptor molecule, suppresses CRACC receptor expression on Antigen Presenting Cells in an ERK MAP kinase dependent mechanism (110.26)
Journal Articles

Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme

Free
Irini Evnouchidou, Ram P. Kamal, Sergey S. Seregin, Yoshikuni Goto, Masafumi Tsujimoto, Akira Hattori, Paraskevi V. Voulgari, Alexandros A. Drosos, Andrea Amalfitano, Ian A. York, Efstratios Stratikos
Journal: The Journal of Immunology
J Immunol (2011) 186 (4): 1909–1913.
https://doi.org/10.4049/jimmunol.1003337
Published: 15 February 2011
View articletitled, Cutting Edge: Coding Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 Can Affect Antigenic Peptide Generation In Vitro by Influencing Basic Enzymatic Properties of the Enzyme
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Includes: Supplementary data
Journal Articles

Expression of the SLAM Family of Receptors Adapter EAT-2 as a Novel Strategy for Enhancing Beneficial Immune Responses to Vaccine Antigens

Free
Yasser A. Aldhamen, Daniel M. Appledorn, Sergey S. Seregin, Chyong-jy J. Liu, Nathaniel J. Schuldt, Sarah Godbehere, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2011) 186 (2): 722–732.
https://doi.org/10.4049/jimmunol.1002105
Published: 15 January 2011
View articletitled, Expression of the SLAM Family of Receptors Adapter EAT-2 as a Novel Strategy for Enhancing Beneficial Immune Responses to Vaccine Antigens
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Includes: Supplementary data
Journal Articles

G-protein coupled receptor kinase-5 mediates Toll-like receptor-4-induced NFκB activation in primary macrophages and in vivo in mice (94.11)

Free
Shipra Shahi, Sonika Patial, Yogesh Saini, Daniel Appledorn, John Lapres, Andrea Amalfitano, Narayanan Parameswaran
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 94.11.
https://doi.org/10.4049/jimmunol.184.Supp.94.11
Published: 01 April 2010
View articletitled, G-protein coupled receptor kinase-5 mediates Toll-like receptor-4-induced NFκB activation in primary macrophages and in vivo in mice (94.11)
Add to Citation Manager for G-protein coupled receptor kinase-5 mediates Toll-like receptor-4-induced NFκB activation in primary macrophages and in vivo in mice (94.11)
Journal Articles

β-arrestins mediate lipopolysaccharide-induced inflammatory response and endotoxemia in mice (94.10)

Free
Narayanan Parameswaran, Babu Gonipeta, Sitaram Parvataneni, Daniel Appledorn, Sonika Patial, Venugopal Gangur, Andrea Amalfitano, Katie Porter
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 94.10.
https://doi.org/10.4049/jimmunol.184.Supp.94.10
Published: 01 April 2010
View articletitled, β-arrestins mediate lipopolysaccharide-induced inflammatory response and endotoxemia in mice (94.10)
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Journal Articles

Adenovirus Vector-Induced Innate Inflammatory Mediators, MAPK Signaling, As Well As Adaptive Immune Responses Are Dependent upon Both TLR2 and TLR9 In Vivo

Free
Daniel M. Appledorn, Sonika Patial, Aaron McBride, Sarah Godbehere, Nico Van Rooijen, Narayanan Parameswaran, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2008) 181 (3): 2134–2144.
https://doi.org/10.4049/jimmunol.181.3.2134
Published: 01 August 2008
View articletitled, Adenovirus Vector-Induced Innate Inflammatory Mediators, MAPK Signaling, As Well As Adaptive Immune Responses Are Dependent upon Both TLR2 and TLR9 In Vivo
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Journal Articles

A New Human Adenoviral Type 4 viral vector system displays highly enhanced immunogenicity that is complement-dependent and correlates with altered adaptive responses (47.24)

Free
Zachary Hartman, Daniel Appledorn, Todd Mendelson, Herbert Kim Lyerly, Tim Clay, Andrea Amalfitano
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S71.
https://doi.org/10.4049/jimmunol.178.Supp.47.24
Published: 01 April 2007
View articletitled, A New Human Adenoviral Type 4 viral vector system displays highly enhanced immunogenicity that is complement-dependent and correlates with altered adaptive responses (47.24)
Add to Citation Manager for A New Human Adenoviral Type 4 viral vector system displays highly enhanced immunogenicity that is complement-dependent and correlates with altered adaptive responses (47.24)
Journal Articles

Modulation of adenoviral vector immune responses through the over-expression of immune adaptor and viral immuno-modulatory genes (48.17)

Free
Zachary Hartman, Xiao Yi Yang, Gangjun Lei, Andrea Amalfitano, Michael Morse, Herbert Kim Lyerly, Tim Clay
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S77–S78.
https://doi.org/10.4049/jimmunol.178.Supp.48.17
Published: 01 April 2007
View articletitled, Modulation of adenoviral vector immune responses through the over-expression of immune adaptor and viral immuno-modulatory genes (48.17)
Add to Citation Manager for Modulation of adenoviral vector immune responses through the over-expression of immune adaptor and viral immuno-modulatory genes (48.17)
Journal Articles

Adenovirus-human HER2 vaccine inhibits breast cancer growth and vaccine induced antibodies (VIA) are efficacious against Herceptin-refractory human breast cancer (48.32)

Free
Junping Wei, Zachary Hartman, Takuya Osada, Xiao Yi Yang, Gangjun Lei, Haixiang Jiang, Gabriel Chong, Andrea Amalfitano, H. Kim Lyerly, Michael Morse, Timothy Clay
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S81.
https://doi.org/10.4049/jimmunol.178.Supp.48.32
Published: 01 April 2007
View articletitled, Adenovirus-human HER2 vaccine inhibits breast cancer growth and vaccine induced antibodies (VIA) are efficacious against Herceptin-refractory human breast cancer (48.32)
Add to Citation Manager for Adenovirus-human HER2 vaccine inhibits breast cancer growth and vaccine induced antibodies (VIA) are efficacious against Herceptin-refractory human breast cancer (48.32)