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Angela M. Thornton
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Journal Articles

Eos is a critical transcription factor for T regulatory cell (Treg) function

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Xuan Xie, Shalini Tanwar, Angela M Thornton, Pat Korty, Owen M Schwartz, Margery Smelkinson, Ethan M Shevach
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 248.04.
https://doi.org/10.4049/jimmunol.210.Supp.248.04
Published: 01 May 2023
View articletitled, Eos is a critical transcription factor for T regulatory cell (Treg) function
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Journal Articles

Acquired Lipodystrophy is Mediated by a Treg Specific Deletion of Helios

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Angela M Thornton, Vinay Penna, Oksana Gavrilova, Ethan M Shevach
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 77.04.
https://doi.org/10.4049/jimmunol.210.Supp.77.04
Published: 01 May 2023
View articletitled, Acquired Lipodystrophy is Mediated by a Treg Specific Deletion of Helios
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Journal Articles

The functional role of Helios in CD4+ T cells

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Neil X Yang, Kole Tison, Vinay Penna, Cihan Oguz, Justin Lack, Ethan M Shevach, Angela M Thornton
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 64.10.
https://doi.org/10.4049/jimmunol.210.Supp.64.10
Published: 01 May 2023
View articletitled, The functional role of Helios in CD4+ T cells
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Journal Articles

Helios expression in CD4+Foxp3− T cells

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Kole Tison, Vinay Penna, Mathias Skadow, Cihan Oguz, Justin Lack, Angela M Thornton, Ethan M Shevach
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 51.15.
https://doi.org/10.4049/jimmunol.206.Supp.51.15
Published: 01 May 2021
View articletitled, Helios expression in CD4+Foxp3− T cells
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Journal Articles

Helios Deficiency Predisposes the Differentiation of CD4+Foxp3− T Cells into Peripherally Derived Regulatory T Cells

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Mathias Skadow, Vinay R. Penna, Jessica Galant-Swafford, Ethan M. Shevach, Angela M. Thornton
Journal: The Journal of Immunology
J Immunol (2019) 203 (2): 370–378.
https://doi.org/10.4049/jimmunol.1900388
Published: 15 July 2019
View articletitled, Helios Deficiency Predisposes the Differentiation of CD4+Foxp3− T Cells into Peripherally Derived Regulatory T Cells
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Includes: Supplementary data
Journal Articles

A Treg-specific deletion of Helios causes autoimmune lipodystrophy and metabolic syndrome

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Angela M Thornton, Oksana F Gavrilova, Vinay R Penna, Patricia E Korty, Ethan M Shevach
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 116.13.
https://doi.org/10.4049/jimmunol.202.Supp.116.13
Published: 01 May 2019
View articletitled, A Treg-specific deletion of Helios causes autoimmune lipodystrophy and metabolic syndrome
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Journal Articles

Helios deletion in CD4+T cells induces pTregs that inhibit memory recall responses

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Vinay Penna, Mathias Skadow, Ethan M Shevach, Angela M Thornton
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 57.7.
https://doi.org/10.4049/jimmunol.202.Supp.57.7
Published: 01 May 2019
View articletitled, Helios deletion in CD4+T cells induces pTregs that inhibit memory recall responses
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Journal Articles

Helios expression defines a phenotypically distinct population of Treg cells

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Angela M. Thornton, Patricia E. Korty, Yong Chan Kim, Craig Martens, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 116.9.
https://doi.org/10.4049/jimmunol.200.Supp.116.9
Published: 01 May 2018
View articletitled, Helios expression defines a phenotypically distinct population of Treg cells
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Journal Articles

Helios plays a critical role in the effective differentiation of naive CD4+ T cells in vivo.

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Mathias Skadow, Ethan M Shevach, Angela M Thornton
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 223.8.
https://doi.org/10.4049/jimmunol.198.Supp.223.8
Published: 01 May 2017
View articletitled, Helios plays a critical role in the effective differentiation of naive CD4+ T cells in vivo.
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Journal Articles

Helios expression defines two distinct populations of Foxp3+ regulatory T cells

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Angela M Thornton, Gokhul Kilaru, Patrick Burr, Sadiye Rieder, Stefan Adi Muljo, Ethan M Shevach
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 125.6.
https://doi.org/10.4049/jimmunol.196.Supp.125.6
Published: 01 May 2016
View articletitled, Helios expression defines two distinct populations of Foxp3+ regulatory T cells
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Journal Articles

Helios Controls a Limited Subset of Regulatory T Cell Functions

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Mathew Sebastian, Maria Lopez-Ocasio, Amina Metidji, Sadiye Amcaoglu Rieder, Ethan M. Shevach, Angela M. Thornton
Journal: The Journal of Immunology
J Immunol (2016) 196 (1): 144–155.
https://doi.org/10.4049/jimmunol.1501704
Published: 01 January 2016
View articletitled, Helios Controls a Limited Subset of Regulatory T Cell Functions
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Includes: Supplementary data
Journal Articles

Eos Is Redundant for Regulatory T Cell Function but Plays an Important Role in IL-2 and Th17 Production by CD4+ Conventional T Cells

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Sadiye Amcaoglu Rieder, Amina Metidji, Deborah Dacek Glass, Angela M. Thornton, Tohru Ikeda, Bruce A. Morgan, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2015) 195 (2): 553–563.
https://doi.org/10.4049/jimmunol.1500627
Published: 15 July 2015
View articletitled, Eos Is Redundant for Regulatory T Cell Function but Plays an Important Role in IL-2 and Th17 Production by CD4+ Conventional T Cells
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Includes: Supplementary data
Journal Articles

Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8

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Justin P. Edwards, Angela M. Thornton, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2014) 193 (6): 2843–2849.
https://doi.org/10.4049/jimmunol.1401102
Published: 15 September 2014
View articletitled, Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8
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Includes: Supplementary data
Journal Articles

A Self-Reactive TCR Drives the Development of Foxp3+ Regulatory T Cells That Prevent Autoimmune Disease

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Justin R. Killebrew, Nikole Perdue, Alan Kwan, Angela M. Thornton, Ethan M. Shevach, Daniel J. Campbell
Journal: The Journal of Immunology
J Immunol (2011) 187 (2): 861–869.
https://doi.org/10.4049/jimmunol.1004009
Published: 15 July 2011
View articletitled, A Self-Reactive TCR Drives the Development of Foxp3+ Regulatory T Cells That Prevent Autoimmune Disease
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Includes: Supplementary data
Journal Articles

Response to Comment on “Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells”

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Angela M. Thornton, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2010) 185 (12): 7130.
https://doi.org/10.4049/jimmunol.1090106
Published: 15 December 2010
View articletitled, Response to Comment on “Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells”
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Journal Articles

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

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Angela M. Thornton, Patricia E. Korty, Dat Q. Tran, Elizabeth A. Wohlfert, Patrick E. Murray, Yasmine Belkaid, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3433–3441.
https://doi.org/10.4049/jimmunol.0904028
Published: 01 April 2010
View articletitled, Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells
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Includes: Supplementary data
Journal Articles

Cutting Edge: CD4 T Cell-Mast Cell Interactions Alter IgE Receptor Expression and Signaling

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Mohit Kashyap, Angela M. Thornton, Sarah Kennedy Norton, Brian Barnstein, Matthew Macey, Jennifer Brenzovich, Ethan Shevach, Warren J. Leonard, John J. Ryan
Journal: The Journal of Immunology
J Immunol (2008) 180 (4): 2039–2043.
https://doi.org/10.4049/jimmunol.180.4.2039
Published: 15 February 2008
View articletitled, Cutting Edge: CD4 T Cell-Mast Cell Interactions Alter IgE Receptor Expression and Signaling
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Journal Articles

Cutting Edge: IL-2 Is Critically Required for the In Vitro Activation of CD4+CD25+ T Cell Suppressor Function

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Angela M. Thornton, Erin E. Donovan, Ciriaco A. Piccirillo, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2004) 172 (11): 6519–6523.
https://doi.org/10.4049/jimmunol.172.11.6519
Published: 01 June 2004
View articletitled, Cutting Edge: IL-2 Is Critically Required for the In Vitro Activation of CD4+CD25+ T Cell Suppressor Function
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Journal Articles

Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific

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Angela M. Thornton, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (2000) 164 (1): 183–190.
https://doi.org/10.4049/jimmunol.164.1.183
Published: 01 January 2000
View articletitled, Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific
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Journal Articles

CD4+CD25+ T Cells Inhibit Both the Induction and Effector Function of Autoreactive T Cells and Represent a Unique Lineage of Immunoregulatory Cells

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Elisabeth Suri-Payer, Anna Z. Amar, Angela M. Thornton, Ethan M. Shevach
Journal: The Journal of Immunology
J Immunol (1998) 160 (3): 1212–1218.
https://doi.org/10.4049/jimmunol.160.3.1212
Published: 01 February 1998
View articletitled, CD4+CD25+ T Cells Inhibit Both the Induction and Effector Function of Autoreactive T Cells and Represent a Unique Lineage of Immunoregulatory Cells
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