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Angela Panoskaltsis-Mortari
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Journal Articles

NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children

Jenna K. Dick, Jules A. Sangala, Venkatramana D. Krishna, Aaron Khaimraj, Lydia Hamel, Spencer M. Erickson, Dustin Hicks, Yvette Soigner, Laura E. Covill, Alexander K. Johnson, Michael J. Ehrhardt, Keenan Ernste, Petter Brodin, Richard A. Koup, Alka Khaitan, Carly Baehr, Beth K. Thielen, Christine M. Henzler, Caleb Skipper, Jeffrey S. Miller, Yenan T. Bryceson, Jianming Wu, Chandy C. John, Angela Panoskaltsis-Mortari, Alberto Orioles, Marie E. Steiner, Maxim C. J. Cheeran, Marco Pravetoni, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2024) 213 (10): 1452–1466.
https://doi.org/10.4049/jimmunol.2400395
Published: 11 October 2024
View article titled, NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children
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Includes: Supplementary data
Journal Articles

Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

Jenna Dick, Dustin Hicks, AnyeDit Jules Sangala, Venkat Krishna, Aaron Khaimraj, Lydia Hamel, Spencer Erickson, Carly Baehr, Christine Henzler, Caleb Skipper, Jianming Wu, Angela Panoskaltsis-Mortari, Alberto Orioles, Marie Steiner, Maxim Cheeran, Marco Pravetoni, Geoffrey Hart
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 0340_4182.
https://doi.org/10.4049/jimmunol.212.supp.0340.4182
Published: 01 May 2024
View article titled, Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)
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Journal Articles

Divergent roles of retinoic acid signaling in T regulatory cell function

Govindarajan Thangavelu, Gabriela Andrejeva, Michael Loschi, Ethan G Aguilar, Yu-Chi Lee, Scott N Furlan, Cameron McDonald-Hyman, Michael C Zaiken, Colby J Feser, Angela Panoskaltsis-Mortari, Leslie S Kean, Jeffrey C Rathmell, Hongbo Chi, Randolph J Noelle, Bruce R Blazar
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 228.4.
https://doi.org/10.4049/jimmunol.204.Supp.228.4
Published: 01 May 2020
View article titled, Divergent roles of retinoic acid signaling in T regulatory cell function
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Journal Articles

B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality

Asim Saha, Patricia A. Taylor, Christopher J. Lees, Angela Panoskaltsis-Mortari, Mark J. Osborn, Colby J. Feser, Govindarajan Thangavelu, Wolfgang Melchinger, Yosef Refaeli, Geoffrey R. Hill, David H. Munn, Jonathan S. Serody, Ivan Maillard, Katharina Kreymborg, Marcel van den Brink, Chen Dong, Shuyu Huang, Xingxing Zang, James P Allison, Robert Zeiser, Bruce R. Blazar
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 69.10.
https://doi.org/10.4049/jimmunol.202.Supp.69.10
Published: 01 May 2019
View article titled, B7-H4 expression in donor T cells and host cells negatively regulates acute graftversus- host disease lethality
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Journal Articles

Innate correlates of influenza clinical outcomes in a multicenter, longitudinal study of critically ill children

Andrew Fiore-Gartland, Angela Panoskaltsis-Mortari, Anna A Agan, Paul Glyndwr Thomas, Tomer Hertz, Adrienne Randolph
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 124.35.
https://doi.org/10.4049/jimmunol.196.Supp.124.35
Published: 01 May 2016
View article titled, Innate correlates of influenza clinical outcomes in a multicenter, longitudinal study of critically ill children
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Journal Articles

Biological role of T Memory Stem Cells as a Cellular Reservoir for Graft-versus-Host Disease

Victor Tkachev, Scott N Furlan, Benjamin K Watkins, Angela Panoskaltsis-Mortari, Bruce R Blazar, Leslie S Kean
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 140.8.
https://doi.org/10.4049/jimmunol.196.Supp.140.8
Published: 01 May 2016
View article titled, Biological role of T Memory Stem Cells as a Cellular Reservoir for Graft-versus-Host Disease
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Journal Articles

Identifying interactions between cytokine levels and clinical outcomes in influenza infection using a novel data-driven method for defining cytokine modules

Tomer Hertz, Andrew Fiore-Gartland, Angela Panoskaltsis-Mortari, Paul Glyndwr Thomas, Adrienne Randolph
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 69.2.
https://doi.org/10.4049/jimmunol.196.Supp.69.2
Published: 01 May 2016
View article titled, Identifying interactions between cytokine levels and clinical outcomes in influenza infection using a novel data-driven method for defining cytokine modules
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Journal Articles

Selective ROCK2 inhibitor reverses experimental chronic graft-versus-host disease via concurrent regulation of STAT3/STAT5 phosphorylation (TRAN1P.933)

Alexandra Zanin-Zhorov, Ryan Flynn, Leo Luznik, melanie Nyuydzefe, Angela Panoskaltsis-Mortari, Jing Du, Katelyn Goodman, Jonathan Weiss, Wei Chen, Jonathan Serody, Kelli MacDonald, Geoffrey Hill, John O'Shea, Samuel Waksal, Bruce Blazar
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 140.15.
https://doi.org/10.4049/jimmunol.194.Supp.140.15
Published: 01 May 2015
View article titled, Selective ROCK2 inhibitor reverses experimental chronic graft-versus-host disease via concurrent regulation of STAT3/STAT5 phosphorylation (TRAN1P.933)
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Journal Articles

Therapeutic treatment of multi-organ system, obstructive pulmonary and scleradermatous chronic graft-versus-host disease with the BTK and ITK inhibitor Ibrutinib (TRAN3P.873)

Ryan Flynn, Jason Dubovsky, Bonnie Harrington, Dawn Reichenbach, Zhong Yiming, Carrie Yang, Will Towns, Amy Lehman, Amy Johnson, Natarajan Muthusamy, Steven Devine, Samantha Jaglowski, Jonathan Serody, William Murphy, David Munn, Leo Luznik, Ivan Maillard, John Koreth, Corey Cutler, Robert Soiffer, Joseph Antin, Jerome Ritz, Angela Panoskaltsis-Mortari, John Byrd, Bruce Blazar
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 202.12.
https://doi.org/10.4049/jimmunol.192.Supp.202.12
Published: 01 May 2014
View article titled, Therapeutic treatment of multi-organ system, obstructive pulmonary and scleradermatous chronic graft-versus-host disease with the BTK and ITK inhibitor Ibrutinib (TRAN3P.873)
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Journal Articles

Attenuation of Acute Graft-versus-Host Disease in the Absence of the Transcription Factor RORγt

LeShara M. Fulton, Michael J. Carlson, James M. Coghill, Laura E. Ott, Michelle L. West, Angela Panoskaltsis-Mortari, Dan R. Littman, Bruce R. Blazar, Jonathan S. Serody
Journal: The Journal of Immunology
J Immunol (2012) 189 (4): 1765–1772.
https://doi.org/10.4049/jimmunol.1200858
Published: 15 August 2012
View article titled, Attenuation of Acute Graft-versus-Host Disease in the Absence of the Transcription Factor RORγt
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Includes: Supplementary data
Journal Articles

STAT3 Signaling in CD4+ T Cells Is Critical for the Pathogenesis of Chronic Sclerodermatous Graft-Versus-Host Disease in a Murine Model

Vedran Radojcic, Maria A. Pletneva, Hung-Rong Yen, Sanja Ivcevic, Angela Panoskaltsis-Mortari, Anita C. Gilliam, Charles G. Drake, Bruce R. Blazar, Leo Luznik
Journal: The Journal of Immunology
J Immunol (2010) 184 (2): 764–774.
https://doi.org/10.4049/jimmunol.0903006
Published: 27 December 2009
View article titled, STAT3 Signaling in CD4<sup>+</sup> T Cells Is Critical for the Pathogenesis of Chronic Sclerodermatous Graft-Versus-Host Disease in a Murine Model
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Includes: Supplementary data
Journal Articles

Deficiency of P-Selectin or P-Selectin Glycoprotein Ligand-1 Leads to Accelerated Development of Glomerulonephritis and Increased Expression of CC Chemokine Ligand 2 in Lupus-Prone Mice

Xiaodong He, Trenton R. Schoeb, Angela Panoskaltsis-Mortari, Kurt R. Zinn, Robert A. Kesterson, Junxuan Zhang, Sharon Samuel, M. John Hicks, Michael J. Hickey, Daniel C. Bullard
Journal: The Journal of Immunology
J Immunol (2006) 177 (12): 8748–8756.
https://doi.org/10.4049/jimmunol.177.12.8748
Published: 15 December 2006
View article titled, Deficiency of P-Selectin or P-Selectin Glycoprotein Ligand-1 Leads to Accelerated Development of Glomerulonephritis and Increased Expression of CC Chemokine Ligand 2 in Lupus-Prone Mice
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Journal Articles

Murine and Human IL-7 Activate STAT5 and Induce Proliferation of Normal Human Pro-B Cells

Sonja E. Johnson, Nisha Shah, Angela Panoskaltsis-Mortari, Tucker W. LeBien
Journal: The Journal of Immunology
J Immunol (2005) 175 (11): 7325–7331.
https://doi.org/10.4049/jimmunol.175.11.7325
Published: 01 December 2005
View article titled, Murine and Human IL-7 Activate STAT5 and Induce Proliferation of Normal Human Pro-B Cells
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Journal Articles

Human Plasmacytoid Dendritic Cells Activated by CpG Oligodeoxynucleotides Induce the Generation of CD4+CD25+ Regulatory T Cells

E. Ashley Moseman, Xueqing Liang, Amanda J. Dawson, Angela Panoskaltsis-Mortari, Arthur M. Krieg, Yong-Jun Liu, Bruce R. Blazar, Wei Chen
Journal: The Journal of Immunology
J Immunol (2004) 173 (7): 4433–4442.
https://doi.org/10.4049/jimmunol.173.7.4433
Published: 01 October 2004
View article titled, Human Plasmacytoid Dendritic Cells Activated by CpG Oligodeoxynucleotides Induce the Generation of CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cells
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Journal Articles

CD30/CD30 Ligand (CD153) Interaction Regulates CD4+ T Cell-Mediated Graft-versus-Host Disease

Bruce R. Blazar, Robert B. Levy, Tak W. Mak, Angela Panoskaltsis-Mortari, Hiromi Muta, Monica Jones, Melinda Roskos, Jonathan S. Serody, Hideo Yagita, Eckhard R. Podack, Patricia A. Taylor
Journal: The Journal of Immunology
J Immunol (2004) 173 (5): 2933–2941.
https://doi.org/10.4049/jimmunol.173.5.2933
Published: 01 September 2004
View article titled, CD30/CD30 Ligand (CD153) Interaction Regulates CD4<sup>+</sup> T Cell-Mediated Graft-versus-Host Disease
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Journal Articles

Differential Roles for CCR5 Expression on Donor T Cells during Graft-versus-Host Disease Based on Pretransplant Conditioning

Christian A. Wysocki, Susan B. Burkett, Angela Panoskaltsis-Mortari, Suzanne L. Kirby, Andrew D. Luster, Karen McKinnon, Bruce R. Blazar, Jonathan S. Serody
Journal: The Journal of Immunology
J Immunol (2004) 173 (2): 845–854.
https://doi.org/10.4049/jimmunol.173.2.845
Published: 15 July 2004
View article titled, Differential Roles for CCR5 Expression on Donor T Cells during Graft-versus-Host Disease Based on Pretransplant Conditioning
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Journal Articles

Blockade of Programmed Death-1 Engagement Accelerates Graft-Versus-Host Disease Lethality by an IFN-γ-Dependent Mechanism

Bruce R. Blazar, Beatriz M. Carreno, Angela Panoskaltsis-Mortari, Laura Carter, Yoshiko Iwai, Hideo Yagita, Hiroyuki Nishimura, Patricia A. Taylor
Journal: The Journal of Immunology
J Immunol (2003) 171 (3): 1272–1277.
https://doi.org/10.4049/jimmunol.171.3.1272
Published: 01 August 2003
View article titled, Blockade of Programmed Death-1 Engagement Accelerates Graft-Versus-Host Disease Lethality by an IFN-γ-Dependent Mechanism
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Journal Articles

The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning

Mercedes Gonzalez, Sergio A. Quezada, Bruce R. Blazar, Angela Panoskaltsis-Mortari, Alexander Y. Rudensky, Randolph J. Noelle
Journal: The Journal of Immunology
J Immunol (2002) 169 (10): 5581–5589.
https://doi.org/10.4049/jimmunol.169.10.5581
Published: 15 November 2002
View article titled, The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning
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A Spontaneous CD8 T Cell-Dependent Autoimmune Disease to an Antigen Expressed Under the Human Keratin 14 Promoter

Maureen A. McGargill, Dita Mayerova, Heather E. Stefanski, Brent Koehn, Evan A. Parke, Stephen C. Jameson, Angela Panoskaltsis-Mortari, Kristin A. Hogquist
Journal: The Journal of Immunology
J Immunol (2002) 169 (4): 2141–2147.
https://doi.org/10.4049/jimmunol.169.4.2141
Published: 15 August 2002
View article titled, A Spontaneous CD8 T Cell-Dependent Autoimmune Disease to an Antigen Expressed Under the Human Keratin 14 Promoter
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Exuberant Inflammation in Nicotinamide Adenine Dinucleotide Phosphate-Oxidase-Deficient Mice After Allogeneic Marrow Transplantation

Shuxia Yang, Angela Panoskaltsis-Mortari, Mayank Shukla, Bruce R. Blazar, Imad Y. Haddad
Journal: The Journal of Immunology
J Immunol (2002) 168 (11): 5840–5847.
https://doi.org/10.4049/jimmunol.168.11.5840
Published: 01 June 2002
View article titled, Exuberant Inflammation in Nicotinamide Adenine Dinucleotide Phosphate-Oxidase-Deficient Mice After Allogeneic Marrow Transplantation
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