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Arlene Sharpe
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Journal Articles

FITS: Framework for In vivo T cell Screens

Samuel Markson, Lauren Milling, Qin Tjokrosurjo, Nicole Derosia, Ivy Streeter, Grant Hickok, Ashlyn Lemmen, Priyamvada Prathima, Thao Nguyen, William Fithian, John Doench, Martin Lafleur, Arlene Sharpe
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 1509_5153.
https://doi.org/10.4049/jimmunol.212.supp.1509.5153
Published: 01 May 2024
View article titled, FITS: Framework for In vivo T cell Screens
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Journal Articles

Monitoring PD-1 Signaling in Tumor Infiltrating Lymphocytes

Xia Bu, Vikram R. Juneja, Katheleen M. Mahoney, Carol G. Renolds, Kathleen A. Mcguire, Seth Maleri, Ping Hua, Baogong Zhu, Sarah R Klein, Edward Greenfield, Philippe Armand, Jerome Ritz, Arlene Sharpe, Gordon J Freeman
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 195.31.
https://doi.org/10.4049/jimmunol.202.Supp.195.31
Published: 01 May 2019
View article titled, Monitoring PD-1 Signaling in Tumor Infiltrating Lymphocytes
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Journal Articles

Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturation

Michael C Zaiken, Ryan Flynn, Katelyn Paz, Stephanie Rhee, Paul Park, Matthew Hemming, Peter Sage, Arlene Sharpe, Leonard Luznik, Ivan Mailard, Geoffrey R. Hill, Kelli MacDonald, Jonathon Serody, Corey Cutler, John Koreth, David Miklos, Joseph Antin, Robert Soiffer, Jerome Ritz, Jay Bradner, Jun Qi, Bruce R. Blazar
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 69.42.
https://doi.org/10.4049/jimmunol.202.Supp.69.42
Published: 01 May 2019
View article titled, Inhibiting EZH2 function prevents and treats chronic graft vs host disease (cGVHD) by disrupting germinal center formation and plasma cell maturation
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Journal Articles

ICOS: ICOS-ligand interaction is essential for ILC2 function and survival (HYP2P.322)

Hadi Maazi, Nisheel Patel, Ishwarya Sankaranarayanan, Diamanda Riagas, Pejman Soroosh, Gordon Freeman, Arlene Sharpe, Omid Akbari
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 53.3.
https://doi.org/10.4049/jimmunol.194.Supp.53.3
Published: 01 May 2015
View article titled, ICOS: ICOS-ligand interaction is essential for ILC2 function and survival (HYP2P.322)
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Journal Articles

RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance (IRC5P.465)

Yanping Xiao, Sanhong Yu, Baogong Zhu, Denis Bedoret, Xia Bu, Loise Francisco, Ping Hua, Jonathan Duke-Cohan, Dale Umetsu, Arlene Sharpe, Rosemarie DeKruyff, Gordon Freeman
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 125.14.
https://doi.org/10.4049/jimmunol.192.Supp.125.14
Published: 01 May 2014
View article titled, RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance (IRC5P.465)
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Journal Articles

Control of microtubule-dependent activation of nucleic acid sensors for antiviral host defenses (INM6P.419)

Hao-Sen Chiang, Yun Zhao, Joo-Hye Song, Song Liu, Ninghai Wang, Cox Terhorst, Arlene Sharpe, Megha Basavappa, Kate Jeffrey, Hans-Christian Reinecker
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 122.16.
https://doi.org/10.4049/jimmunol.192.Supp.122.16
Published: 01 May 2014
View article titled, Control of microtubule-dependent activation of nucleic acid sensors for antiviral host defenses (INM6P.419)
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Journal Articles

Correction: Crucial Role of Granulocytic Myeloid-Derived Suppressor Cells in the Regulation of Central Nervous System Autoimmune Disease

Marianna Ioannou, Themis Alissafi, Iakovos Lazaridis, George Deraos, John Matsoukas, Achille Gravanis, Vasileios Mastorodemos, Andreas Plaitakis, Arlene Sharpe, Dimitrios Boumpas, Panayotis Verginis
Journal: The Journal of Immunology
J Immunol (2014) 192 (3): 1334.
https://doi.org/10.4049/jimmunol.1390073
Published: 01 February 2014
View article titled, Correction: Crucial Role of Granulocytic Myeloid-Derived Suppressor Cells in the Regulation of Central Nervous System Autoimmune Disease
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Journal Articles

Programmed death ligand 2 is a regulator of proinflammatory Th17 responses and immunopathology in murine infection with Schistosoma mansoni (P3085)

Danielle Salantes, Bridget Larkin, Holly Ponichtera, Arlene Sharpe, Miguel Stadecker
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 187.15.
https://doi.org/10.4049/jimmunol.190.Supp.187.15
Published: 01 May 2013
View article titled, Programmed death ligand 2 is a regulator of proinflammatory Th17 responses and immunopathology in murine infection with <em>Schistosoma mansoni</em> (P3085)
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Journal Articles

Generation and characterization of a CXCR3-EGFP bicistronic reporter (CIBER) mouse reveals phenotypically and functionally distinct populations of innate CD8+ T cells (44.9)

Steve Oghumu, Ran Dong, Todd Shawler, Thomas Kampfrath, Sanjay Rajagopalan, Arlene Sharpe, Abhay Satoskar
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 44.9.
https://doi.org/10.4049/jimmunol.188.Supp.44.9
Published: 01 May 2012
View article titled, Generation and characterization of a CXCR3-EGFP bicistronic reporter (CIBER) mouse reveals phenotypically and functionally distinct populations of innate CD8+ T cells (44.9)
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Journal Articles

IL-27 priming of T cells controls IL-17-production in trans via induction of PD-L1 (59.1)

Kiyoshi Hirahara, Kamran Ghoreschi, Xiang-Ping Yang, Hayato Takahashi, Arian Laurence, Golnaz Vahedi, Giuseppe Sciumè, Aisling Hall, Christopher Dupont, Loise Francisco, Qian Chen, Masao Tanaka, Yuka Kanno, Hong-Wei Sun, Arlene Sharpe, Christopher Hunter, John O’Shea
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 59.1.
https://doi.org/10.4049/jimmunol.188.Supp.59.1
Published: 01 May 2012
View article titled, IL-27 priming of T cells controls IL-17-production in <em>trans</em> via induction of PD-L1 (59.1)
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Journal Articles

Induced-tolerogenic Dendritic Cells promote tolerance and de novo differentiation of regulatory T cells (65.6)

Roberto Maldonado, L. Carolina Perdomo, Fulvia Vascotto, Aurelie Bauquet, Arlene Sharpe, Vijay Kuchroo, Ulrich von Andrian
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 65.6.
https://doi.org/10.4049/jimmunol.188.Supp.65.6
Published: 01 May 2012
View article titled, Induced-tolerogenic Dendritic Cells promote tolerance and de novo differentiation of regulatory T cells (65.6)
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Journal Articles

Intestinal dendritic cells survey circulatory antigens prior to induction of regulatory CD8α/β T cells (106.2)

Joo Hye Song, Sun Young Change, Bayasi Guleng, Carmen Cotoner, Seiji Arihiro, Christopher Karp, Mi-Na Kweon, Arlene Sharpe, Atul Bhan, Cox Terhors, Hans-Christian Reinecker
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 106.2.
https://doi.org/10.4049/jimmunol.188.Supp.106.2
Published: 01 May 2012
View article titled, Intestinal dendritic cells survey circulatory antigens prior to induction of regulatory CD8α/β T cells (106.2)
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Journal Articles

Sexually dimorphic control of regulatory T cell function and autoimmunity protection through B7-H1 and estrogen signals (123.50)

Tyler Curiel, Mark Kious, Benjamin Daniel, Pei Lin, Suzanne Thibodeaux, Ratna Vadlamudi, Margaret Wierman, Laurence Turka, Ruan Zhang, Arlene Sharpe, Loise Francisco, Sun Lishi, Srilakshmi Pandaswara, Rajeshwar Tekmal, Vincent Hurez
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 123.50.
https://doi.org/10.4049/jimmunol.188.Supp.123.50
Published: 01 May 2012
View article titled, Sexually dimorphic control of regulatory T cell function and autoimmunity protection through B7-H1 and estrogen signals (123.50)
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Journal Articles

DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of cognate CD8+ T cells independently of the PD-1 pathway (123.19)

Gayatri Mukherjee, Ari Geliebter, Arlene Sharpe, Gordon Freeman, Teresa DiLorenzo
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 123.19.
https://doi.org/10.4049/jimmunol.188.Supp.123.19
Published: 01 May 2012
View article titled, DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of cognate CD8<sup>+</sup> T cells independently of the PD-1 pathway (123.19)
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Journal Articles

Crucial Role of Granulocytic Myeloid-Derived Suppressor Cells in the Regulation of Central Nervous System Autoimmune Disease

Marianna Ioannou, Themis Alissafi, Iakovos Lazaridis, George Deraos, John Matsoukas, Achille Gravanis, Vasileios Mastorodemos, Andreas Plaitakis, Arlene Sharpe, Dimitrios Boumpas, Panayotis Verginis
Journal: The Journal of Immunology
J Immunol (2012) 188 (3): 1136–1146.
https://doi.org/10.4049/jimmunol.1101816
Published: 01 February 2012
View article titled, Crucial Role of Granulocytic Myeloid-Derived Suppressor Cells in the Regulation of Central Nervous System Autoimmune Disease
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Includes: Supplementary data
Journal Articles

The PD-Ligand Pathway regulates the development, maintenance and function of induced regulatory T cells in vitro and in vivo (49.16)

Loise Francisco, Victor Salinas, Keturah Brown, Vijay Vanguri, Gordon Freeman, Vijay Kuchroo, Arlene Sharpe
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 49.16.
https://doi.org/10.4049/jimmunol.184.Supp.49.16
Published: 01 April 2010
View article titled, The PD-Ligand Pathway regulates the development, maintenance and function of induced regulatory T cells in vitro and in vivo (49.16)
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Journal Articles

OX40L mediates susceptibility to chronic Leishmania donovani infection (40.26)

Heidi Snider, Patrick Reville, Arlene Sharpe, Abhay Satoskar
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 40.26.
https://doi.org/10.4049/jimmunol.184.Supp.40.26
Published: 01 April 2010
View article titled, OX40L mediates susceptibility to chronic <em>Leishmania donovani</em> infection (40.26)
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Journal Articles

Paradoxical Effect of Reduced Costimulation in T Cell-Mediated Colitis

Gisen Kim, Matthew Levin, Stephen P. Schoenberger, Arlene Sharpe, Mitchell Kronenberg
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5563–5570.
https://doi.org/10.4049/jimmunol.178.9.5563
Published: 01 May 2007
View article titled, Paradoxical Effect of Reduced Costimulation in T Cell-Mediated Colitis
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Journal Articles

Paradoxical Dampening of Anti-Islet Self-Reactivity but Promotion of Diabetes by OX40 Ligand

Natalia Martin-Orozco, Zhibin Chen, Laurent Poirot, Elzbieta Hyatt, Andy Chen, Osami Kanagawa, Arlene Sharpe, Diane Mathis, Christophe Benoist
Journal: The Journal of Immunology
J Immunol (2003) 171 (12): 6954–6960.
https://doi.org/10.4049/jimmunol.171.12.6954
Published: 15 December 2003
View article titled, Paradoxical Dampening of Anti-Islet Self-Reactivity but Promotion of Diabetes by OX40 Ligand
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Journal Articles

Cutting Edge: Transplantation Tolerance through Enhanced CTLA-4 Expression

Charlotte Ariyan, Paolo Salvalaggio, Scott Fecteau, Songyan Deng, Linda Rogozinski, Didier Mandelbrot, Arlene Sharpe, Mohamed H. Sayegh, Giacomo P. Basadonna, David M. Rothstein
Journal: The Journal of Immunology
J Immunol (2003) 171 (11): 5673–5677.
https://doi.org/10.4049/jimmunol.171.11.5673
Published: 01 December 2003
View article titled, Cutting Edge: Transplantation Tolerance through Enhanced CTLA-4 Expression
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