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Arne N. Akbar
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Journal Articles

Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5′-Monophosphate–Activated Protein Kinase

Bojana Müller-Durovic, Alessio Lanna, Luciana Polaco Covre, Rachel S. Mills, Sian M. Henson, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2016) 197 (7): 2891–2899.
https://doi.org/10.4049/jimmunol.1600590
Published: 01 October 2016
View articletitled, Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5′-Monophosphate–Activated Protein Kinase
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Includes: Supplementary data
Journal Articles

IFN-α Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling

Alessio Lanna, Elias Coutavas, Lauretta Levati, Judith Seidel, Malcolm H. A. Rustin, Sian M. Henson, Arne N. Akbar, Ornella Franzese
Journal: The Journal of Immunology
J Immunol (2013) 191 (7): 3744–3752.
https://doi.org/10.4049/jimmunol.1301409
Published: 01 October 2013
View articletitled, IFN-α Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling
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Includes: Supplementary data
Journal Articles

Age-Associated Increase of Low-Avidity Cytomegalovirus-Specific CD8+ T Cells That Re-Express CD45RA

Stephen J. Griffiths, Natalie E. Riddell, Joanne Masters, Valentina Libri, Sian M. Henson, Anne Wertheimer, Diana Wallace, Stuart Sims, Laura Rivino, Anis Larbi, David M. Kemeny, Janko Nikolich-Zugich, Florian Kern, Paul Klenerman, Vince C. Emery, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2013) 190 (11): 5363–5372.
https://doi.org/10.4049/jimmunol.1203267
Published: 01 June 2013
View articletitled, Age-Associated Increase of Low-Avidity Cytomegalovirus-Specific CD8+ T Cells That Re-Express CD45RA
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Includes: Supplementary data
Journal Articles

Varicella Zoster–Specific CD4+Foxp3+ T Cells Accumulate after Cutaneous Antigen Challenge in Humans

Milica Vukmanovic-Stejic, Daisy Sandhu, Toni O. Sobande, Elaine Agius, Katie E. Lacy, Natalie Riddell, Sandra Montez, One B. Dintwe, Thomas J. Scriba, Judith Breuer, Janko Nikolich-Žugich, Graham Ogg, Malcolm H. A. Rustin, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2013) 190 (3): 977–986.
https://doi.org/10.4049/jimmunol.1201331
Published: 01 February 2013
View articletitled, Varicella Zoster–Specific CD4+Foxp3+ T Cells Accumulate after Cutaneous Antigen Challenge in Humans
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Includes: Supplementary data
Journal Articles

Reversible Senescence in Human CD4+CD45RA+CD27− Memory T Cells

Diletta Di Mitri, Rita I. Azevedo, Sian M. Henson, Valentina Libri, Natalie E. Riddell, Richard Macaulay, David Kipling, Maria V. D. Soares, Luca Battistini, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2011) 187 (5): 2093–2100.
https://doi.org/10.4049/jimmunol.1100978
Published: 01 September 2011
View articletitled, Reversible Senescence in Human CD4+CD45RA+CD27− Memory T Cells
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Includes: Supplementary data
Journal Articles

Different Proliferative Potential and Migratory Characteristics of Human CD4+ Regulatory T Cells That Express either CD45RA or CD45RO

Nicola J. Booth, Arthur J. McQuaid, Toni Sobande, Steve Kissane, Elaine Agius, Sarah E. Jackson, Mike Salmon, Francesco Falciani, Kwee Yong, Malcolm H. Rustin, Arne N. Akbar, Milica Vukmanovic-Stejic
Journal: The Journal of Immunology
J Immunol (2010) 184 (8): 4317–4326.
https://doi.org/10.4049/jimmunol.0903781
Published: 15 April 2010
View articletitled, Different Proliferative Potential and Migratory Characteristics of Human CD4+ Regulatory T Cells That Express either CD45RA or CD45RO
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Includes: Supplementary data
Journal Articles

Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool

Pablo J. E. J. van de Berg, Stephen J. Griffiths, Si-La Yong, Richard Macaulay, Frederike J. Bemelman, Sarah Jackson, Sian M. Henson, Ineke J. M. ten Berge, Arne N. Akbar, René A. W. van Lier
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3417–3423.
https://doi.org/10.4049/jimmunol.0903442
Published: 01 April 2010
View articletitled, Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool
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Includes: Supplementary data
Journal Articles

The Loss of Telomerase Activity in Highly Differentiated CD8+CD28−CD27− T Cells Is Associated with Decreased Akt (Ser473) Phosphorylation

Fiona J. Plunkett, Ornella Franzese, Helene M. Finney, Jean M. Fletcher, Lavina L. Belaramani, Mike Salmon, Inderjeet Dokal, David Webster, Alastair D. G. Lawson, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2007) 178 (12): 7710–7719.
https://doi.org/10.4049/jimmunol.178.12.7710
Published: 15 June 2007
View articletitled, The Loss of Telomerase Activity in Highly Differentiated CD8+CD28−CD27− T Cells Is Associated with Decreased Akt (Ser473) Phosphorylation
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Journal Articles

Telomerase in T Lymphocytes: Use It and Lose It?

In Special Collection:
Brief Reviews
Arne N. Akbar, Milica Vukmanovic-Stejic
Journal: The Journal of Immunology
J Immunol (2007) 178 (11): 6689–6694.
https://doi.org/10.4049/jimmunol.178.11.6689
Published: 01 June 2007
View articletitled, Telomerase in T Lymphocytes: Use It and Lose It?
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Journal Articles

Cytomegalovirus-Specific CD4+ T Cells in Healthy Carriers Are Continuously Driven to Replicative Exhaustion

Jean M. Fletcher, Milica Vukmanovic-Stejic, Padraic J. Dunne, Katie E. Birch, Joanne E. Cook, Sarah E. Jackson, Mike Salmon, Malcolm H. Rustin, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2005) 175 (12): 8218–8225.
https://doi.org/10.4049/jimmunol.175.12.8218
Published: 15 December 2005
View articletitled, Cytomegalovirus-Specific CD4+ T Cells in Healthy Carriers Are Continuously Driven to Replicative Exhaustion
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Journal Articles

Topical Glucocorticoid Therapy Directly Induces Up-Regulation of Functional CXCR4 on Primed T Lymphocytes in the Aqueous Humor of Patients with Uveitis

S. John Curnow, Kaska Wloka, Jeff M. Faint, Nicole Amft, C. M. Gemmy Cheung, Vijay Savant, Janet Lord, Arne N. Akbar, Christopher D. Buckley, Philip I. Murray, Mike Salmon
Journal: The Journal of Immunology
J Immunol (2004) 172 (11): 7154–7161.
https://doi.org/10.4049/jimmunol.172.11.7154
Published: 01 June 2004
View articletitled, Topical Glucocorticoid Therapy Directly Induces Up-Regulation of Functional CXCR4 on Primed T Lymphocytes in the Aqueous Humor of Patients with Uveitis
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Journal Articles

Activation of Resting Human Primary T Cells with Chimeric Receptors: Costimulation from CD28, Inducible Costimulator, CD134, and CD137 in Series with Signals from the TCRζ Chain

Helene M. Finney, Arne N. Akbar, Alastair D. G. Lawson
Journal: The Journal of Immunology
J Immunol (2004) 172 (1): 104–113.
https://doi.org/10.4049/jimmunol.172.1.104
Published: 01 January 2004
View articletitled, Activation of Resting Human Primary T Cells with Chimeric Receptors: Costimulation from CD28, Inducible Costimulator, CD134, and CD137 in Series with Signals from the TCRζ Chain
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Journal Articles

Inhibition of Neutrophil Apoptosis by Type 1 IFN Depends on Cross-Talk Between Phosphoinositol 3-Kinase, Protein Kinase C-δ, and NF-κB Signaling Pathways

KeQing Wang, Dagmar Scheel-Toellner, See Heng Wong, Rachel Craddock, Jorge Caamano, Arne N. Akbar, Mike Salmon, Janet M. Lord
Journal: The Journal of Immunology
J Immunol (2003) 171 (2): 1035–1041.
https://doi.org/10.4049/jimmunol.171.2.1035
Published: 15 July 2003
View articletitled, Inhibition of Neutrophil Apoptosis by Type 1 IFN Depends on Cross-Talk Between Phosphoinositol 3-Kinase, Protein Kinase C-δ, and NF-κB Signaling Pathways
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Journal Articles

Memory T Cells Constitute a Subset of the Human CD8+CD45RA+ Pool with Distinct Phenotypic and Migratory Characteristics

Jeffery M. Faint, Nicola E. Annels, S. John Curnow, Philip Shields, Darrell Pilling, Andrew D. Hislop, Lijun Wu, Arne N. Akbar, Christopher D. Buckley, Paul A. H. Moss, David H. Adams, Alan B. Rickinson, Mike Salmon
Journal: The Journal of Immunology
J Immunol (2001) 167 (1): 212–220.
https://doi.org/10.4049/jimmunol.167.1.212
Published: 01 July 2001
View articletitled, Memory T Cells Constitute a Subset of the Human CD8+CD45RA+ Pool with Distinct Phenotypic and Migratory Characteristics
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Journal Articles

Type 1 IFN Maintains the Survival of Anergic CD4+ T Cells

Giovanna Lombardi, Pádraic J. Dunne, Dagmar Scheel-Toellner, Tina Sanyal, Darrell Pilling, Leonie S. Taams, Paul Life, Janet M. Lord, Mike Salmon, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (2000) 165 (7): 3782–3789.
https://doi.org/10.4049/jimmunol.165.7.3782
Published: 01 October 2000
View articletitled, Type 1 IFN Maintains the Survival of Anergic CD4+ T Cells
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Journal Articles

Virus-Induced CD8+ T Cell Clonal Expansion Is Associated with Telomerase Up-Regulation and Telomere Length Preservation: A Mechanism for Rescue from Replicative Senescence

Mala K. Maini, Maria Vieira D. Soares, Christian F. Zilch, Arne N. Akbar, Peter C. L. Beverley
Journal: The Journal of Immunology
J Immunol (1999) 162 (8): 4521–4526.
https://doi.org/10.4049/jimmunol.162.8.4521
Published: 15 April 1999
View articletitled, Virus-Induced CD8+ T Cell Clonal Expansion Is Associated with Telomerase Up-Regulation and Telomere Length Preservation: A Mechanism for Rescue from Replicative Senescence
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Journal Articles

IL-7-Dependent Extrathymic Expansion of CD45RA+ T Cells Enables Preservation of a Naive Repertoire

Maria Vieira, D. Soares, Nicola J. Borthwick, Mala K. Maini, George Janossy, Mike Salmon, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (1998) 161 (11): 5909–5917.
https://doi.org/10.4049/jimmunol.161.11.5909
Published: 01 December 1998
View articletitled, IL-7-Dependent Extrathymic Expansion of CD45RA+ T Cells Enables Preservation of a Naive Repertoire
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Journal Articles

The Role of Apoptosis in the Resolution of T Cell-Mediated Cutaneous Inflammation

Catherine H. Orteu, Len W. Poulter, Malcolm H. A. Rustin, Caroline A. Sabin, Mike Salmon, Arne N. Akbar
Journal: The Journal of Immunology
J Immunol (1998) 161 (4): 1619–1629.
https://doi.org/10.4049/jimmunol.161.4.1619
Published: 15 August 1998
View articletitled, The Role of Apoptosis in the Resolution of T Cell-Mediated Cutaneous Inflammation
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