1-20 of 46
Ashok Kumar
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

HIF-1α Regulation of Cytokine Production following TLR3 Engagement in Murine Bone Marrow–Derived Macrophages Is Dependent on Viral Nucleic Acid Length and Glucose Availability

Duale Ahmed, Allan Humphrey, David Roy, Mary-Elizabeth Sheridan, Zoya Versey, Allison Jaworski, Alex Edwards, James Donner, Alfonso Abizaid, William Willmore, Ashok Kumar, Ashkan Golshani, Edana Cassol
Journal: The Journal of Immunology
J Immunol (2021) 207 (11): 2813–2827.
https://doi.org/10.4049/jimmunol.2001282
Published: 01 December 2021
View article titled, HIF-1α Regulation of Cytokine Production following TLR3 Engagement in Murine Bone Marrow–Derived Macrophages Is Dependent on Viral Nucleic Acid Length and Glucose Availability
Open the PDF for HIF-1α Regulation of Cytokine Production following TLR3 Engagement in Murine Bone Marrow–Derived Macrophages Is Dependent on Viral Nucleic Acid Length and Glucose Availability in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Selective Induction of Cell Death in Human M1 Macrophages by Smac Mimetics Is Mediated by cIAP-2 and RIPK-1/3 through the Activation of mTORC

Hamza Ali, Simon Xin Min Dong, Niranjala Gajanayaka, Edana Cassol, Jonathan B. Angel, Ashok Kumar
Journal: The Journal of Immunology
J Immunol (2021) 207 (9): 2359–2373.
https://doi.org/10.4049/jimmunol.2100108
Published: 01 November 2021
View article titled, Selective Induction of Cell Death in Human M1 Macrophages by Smac Mimetics Is Mediated by cIAP-2 and RIPK-1/3 through the Activation of mTORC
Open the PDF for Selective Induction of Cell Death in Human M1 Macrophages by Smac Mimetics Is Mediated by cIAP-2 and RIPK-1/3 through the Activation of mTORC in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

TLR-4 Agonist Induces IFN-γ Production Selectively in Proinflammatory Human M1 Macrophages through the PI3K-mTOR– and JNK-MAPK–Activated p70S6K Pathway

Niranjala Gajanayaka, Simon Xin Min Dong, Hamza Ali, Salma Iqbal, Ananda Mookerjee, David A Lawton, Ramon Edwin Caballero, Edana Cassol, Donald William Cameron, Jonathan B. Angel, Angela M. Crawley, Ashok Kumar
Journal: The Journal of Immunology
J Immunol (2021) 207 (9): 2310–2324.
https://doi.org/10.4049/jimmunol.2001191
Published: 01 November 2021
View article titled, TLR-4 Agonist Induces IFN-γ Production Selectively in Proinflammatory Human M1 Macrophages through the PI3K-mTOR– and JNK-MAPK–Activated p70S6K Pathway
Open the PDF for TLR-4 Agonist Induces IFN-γ Production Selectively in Proinflammatory Human M1 Macrophages through the PI3K-mTOR– and JNK-MAPK–Activated p70S6K Pathway in another window
Add to Citation Manager
Journal Articles

IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology

Ferrin Antony, Chetan Pundkar, Maninder Sandey, Anil K. Jaiswal, Amarjit Mishra, Ashok Kumar, Rudragouda Channappanavar, Amol Suryawanshi
Journal: The Journal of Immunology
J Immunol (2021) 206 (8): 1866–1877.
https://doi.org/10.4049/jimmunol.2000979
Published: 15 April 2021
View article titled, IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology
Open the PDF for IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1–Induced Corneal Immunopathology in another window
Add to Citation Manager
Journal Articles

Selective killing of proinflammatory human M1 macrophages by SMAC mimetics and anti-inflammatory M2 macrophages by SMAC mimetics and caspase inhibitors

Ashok Kumar, Hamza Ali
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 149.30.
https://doi.org/10.4049/jimmunol.204.Supp.149.30
Published: 01 May 2020
View article titled, Selective killing of proinflammatory human M1 macrophages by SMAC mimetics and anti-inflammatory M2 macrophages by SMAC mimetics and caspase inhibitors
Add to Citation Manager
Journal Articles

AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis

Sneha Singh, Pawan Kumar Singh, Hamid Suhail, Vaithilingaraja Arumugaswami, Philip E. Pellett, Shailendra Giri, Ashok Kumar
Journal: The Journal of Immunology
J Immunol (2020) 204 (7): 1810–1824.
https://doi.org/10.4049/jimmunol.1901310
Published: 01 April 2020
View article titled, AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis
Open the PDF for AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Glycolytic regulation of neuroinflammatory response: Role of monocarboxylate transporter 4

Shailendra Giri, Jaspreet Singh, Hamid Suhail, Ashok Kumar, Ramandeep Rattan
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 183.12.
https://doi.org/10.4049/jimmunol.202.Supp.183.12
Published: 01 May 2019
View article titled, Glycolytic regulation of neuroinflammatory response: Role of monocarboxylate transporter 4
Add to Citation Manager
Journal Articles

TLR-2, TLR-3 and TLR-4 agonists induce synthesis of IFN-γ in human M1 but not in M2a, M2b and M2c macrophages through the activation of S6K1-S6 pathwayγ

Ashok Kumar, Salma Iqbal, Ananda Mukerjee, Niranjala Gajnayaka, Faria Ahmad, Angela Crawley
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 64.23.
https://doi.org/10.4049/jimmunol.202.Supp.64.23
Published: 01 May 2019
View article titled, TLR-2, TLR-3 and TLR-4 agonists induce synthesis of IFN-γ in human M1 but not in M2a, M2b and M2c macrophages through the activation of S6K1-S6 pathwayγ
Add to Citation Manager
Journal Articles

Activation of AMPK restricts Zika virus replication in endothelial cells by potentiating antiviral response and inhibiting viral-induced glycolysis

Ashok Kumar, Sneha Singh, Pawan Singh, Shailendra Giri
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 127.19.
https://doi.org/10.4049/jimmunol.202.Supp.127.19
Published: 01 May 2019
View article titled, Activation of AMPK restricts Zika virus replication in endothelial cells by potentiating antiviral response and inhibiting viral-induced glycolysis
Add to Citation Manager
Journal Articles

Early burst of glycolysis in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuro-inflammation

Shailendra Giri, Hamid Suhail, Jaspreet Singh, Ashok Kumar, Ramandeep Rattan
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 49.16.
https://doi.org/10.4049/jimmunol.200.Supp.49.16
Published: 01 May 2018
View article titled, Early burst of glycolysis in microglia regulates mitochondrial dysfunction in oligodendrocytes under neuro-inflammation
Add to Citation Manager
Journal Articles

AMP-activated kinase (AMPK) promotes innate immunity and antiviral defense against Zika virus induced ocular infection

Ashok Kumar, Pawan Kumar Singh, Shailendra Giri
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 50.14.
https://doi.org/10.4049/jimmunol.200.Supp.50.14
Published: 01 May 2018
View article titled, AMP-activated kinase (AMPK) promotes innate immunity and antiviral defense against Zika virus induced ocular infection
Add to Citation Manager
Journal Articles

cIAP1/2-TRAF2- SHP1-Src-MyD88 complex regulates LPS-induced IL-27 production through NFkB activation in human macrophages

Ashok Kumar, Aurelia Busca, Niranjala Gajanayaka, Jonathan Angel
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 49.3.
https://doi.org/10.4049/jimmunol.200.Supp.49.3
Published: 01 May 2018
View article titled, cIAP1/2-TRAF2- SHP1-Src-MyD88 complex regulates LPS-induced IL-27 production through NFkB activation in human macrophages
Add to Citation Manager
Journal Articles

cIAP1/2–TRAF2–SHP-1–Src–MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages

Aurelia Busca, Yulia Konarski, Niranjala Gajanayaka, Shifawn O’Hara, Jonathan Angel, Maya Kozlowski, Ashok Kumar
Journal: The Journal of Immunology
J Immunol (2018) 200 (5): 1593–1606.
https://doi.org/10.4049/jimmunol.1700199
Published: 01 March 2018
View article titled, cIAP1/2–TRAF2–SHP-1–Src–MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages
Open the PDF for cIAP1/2–TRAF2–SHP-1–Src–MyD88 Complex Regulates Lipopolysaccharide-Induced IL-27 Production through NF-κB Activation in Human Macrophages in another window
Add to Citation Manager
Journal Articles

HDAC3 controls homeostasis of retina-resident microglia derived from embryonic precursors

Xiaofan Mi, Yi Yao, Queping Liu, Ashok Kumar, Hua Gao, Li Zhou, Qing-Sheng Mi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 62.13.
https://doi.org/10.4049/jimmunol.198.Supp.62.13
Published: 01 May 2017
View article titled, HDAC3 controls homeostasis of retina-resident microglia derived from embryonic precursors
Add to Citation Manager
Journal Articles

AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage–Th17 Axis

Ashutosh K. Mangalam, Ramandeep Rattan, Hamid Suhail, Jaspreet Singh, Md Nasrul Hoda, Mandar Deshpande, Sadanand Fulzele, Alexander Denic, Viji Shridhar, Ashok Kumar, Benoit Viollet, Moses Rodriguez, Shailendra Giri
Journal: The Journal of Immunology
J Immunol (2016) 197 (3): 747–760.
https://doi.org/10.4049/jimmunol.1501549
Published: 01 August 2016
View article titled, AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage–Th17 Axis
Open the PDF for AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage–Th17 Axis in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Human Xenobiotic Nuclear Receptor PXR Augments Mycobacterium tuberculosis Survival

Ella Bhagyaraj, Ravikanth Nanduri, Ankita Saini, Hedwin Kitdorlang Dkhar, Nancy Ahuja, Vemika Chandra, Sahil Mahajan, Rashi Kalra, Drishti Tiwari, Charu Sharma, Ashok Kumar Janmeja, Pawan Gupta
Journal: The Journal of Immunology
J Immunol (2016) 197 (1): 244–255.
https://doi.org/10.4049/jimmunol.1600203
Published: 01 July 2016
View article titled, Human Xenobiotic Nuclear Receptor PXR Augments <em>Mycobacterium tuberculosis</em> Survival
Open the PDF for Human Xenobiotic Nuclear Receptor PXR Augments <em>Mycobacterium tuberculosis</em> Survival in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Bacterial DNA Protects Monocytic Cells against HIV-Vpr–Induced Mitochondrial Membrane Depolarization

Mansi Saxena, Aurelia Busca, Martin Holcik, Ashok Kumar
Journal: The Journal of Immunology
J Immunol (2016) 196 (9): 3754–3767.
https://doi.org/10.4049/jimmunol.1402379
Published: 01 May 2016
View article titled, Bacterial DNA Protects Monocytic Cells against HIV-Vpr–Induced Mitochondrial Membrane Depolarization
Open the PDF for Bacterial DNA Protects Monocytic Cells against HIV-Vpr–Induced Mitochondrial Membrane Depolarization in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

HIV and HIV Tat inhibit LPS-induced IL-23 production in human macrophages by distinct intracellular signaling pathways

Ashok Kumar, Niranjala Gajnayaka, Jonathan Angel
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 217.17.
https://doi.org/10.4049/jimmunol.196.Supp.217.17
Published: 01 May 2016
View article titled, HIV and HIV Tat inhibit LPS-induced IL-23 production in human macrophages by distinct intracellular signaling pathways
Add to Citation Manager
Journal Articles

HIV inhibits LPS-induced IL-27 production via HIV tat through the inhibition of TRAF-6, and consequent inhibition of PI3K and p38 and JNK MAPKs in human macrophages (VIR9P.1140)

Ashok Kumar, Niranjala Gajnayaka, Jason Fernandez, Jonathan Angel, Maya Kozlowski
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 215.6.
https://doi.org/10.4049/jimmunol.194.Supp.215.6
Published: 01 May 2015
View article titled, HIV inhibits LPS-induced IL-27 production via HIV tat through the inhibition of TRAF-6, and consequent inhibition of PI3K and p38 and JNK MAPKs in human macrophages (VIR9P.1140)
Add to Citation Manager
Journal Articles

SHP-1–Pyk2–Src Protein Complex and p38 MAPK Pathways Independently Regulate IL-10 Production in Lipopolysaccharide-Stimulated Macrophages

Chinonso Okenwa, Ashok Kumar, Dorothy Rego, Yulia Konarski, Ladan Nilchi, Kathryn Wright, Maya Kozlowski
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2589–2603.
https://doi.org/10.4049/jimmunol.1300466
Published: 01 September 2013
View article titled, SHP-1–Pyk2–Src Protein Complex and p38 MAPK Pathways Independently Regulate IL-10 Production in Lipopolysaccharide-Stimulated Macrophages
Open the PDF for SHP-1–Pyk2–Src Protein Complex and p38 MAPK Pathways Independently Regulate IL-10 Production in Lipopolysaccharide-Stimulated Macrophages in another window
Add to Citation Manager