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B. Paul Morgan
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Journal Articles

Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features

Free
Nirmal K. Banda, Kevin D. Deane, Elizabeth A. Bemis, Colin Strickland, Jennifer Seifert, Kimberly Jordan, Katriona Goldman, B. Paul Morgan, Larry W. Moreland, Myles J. Lewis, Costantino Pitzalis, V. Michael Holers
Journal: The Journal of Immunology
J Immunol (2022) 208 (11): 2482–2496.
https://doi.org/10.4049/jimmunol.2101170
Published: 01 June 2022
View articletitled, Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features
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Includes: Supplementary data
Journal Articles

A Snap Shot of Complement Gene Expression and Presence of Complement Proteins in Synovial Biopsies from Early Rheumatoid Arthritis Patients

Free
Nirmal K Banda, Kevin D Deane, Jennifer Seifert, Colin Strickland, Elizabeth Bemis, Kimberly Jordan, Kationa Goldmann, Accelerating Medicines Partnership (AMP) RA/SLE Network, B. Paul Morgan, Myles J Lewis, Costantino Pitzalis, Larry W Moreland, V. Michael Holers
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 108.03.
https://doi.org/10.4049/jimmunol.208.Supp.108.03
Published: 01 May 2022
View articletitled, A Snap Shot of Complement Gene Expression and Presence of Complement Proteins in Synovial Biopsies from Early Rheumatoid Arthritis Patients
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Journal Articles

Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene

Free
Hani Boshra, Wioleta M. Zelek, Timothy R. Hughes, Santiago Rodriguez de Cordoba, B. Paul Morgan
Journal: The Journal of Immunology
J Immunol (2018) 200 (1): 327–335.
https://doi.org/10.4049/jimmunol.1701238
Published: 01 January 2018
View articletitled, Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene
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Includes: Supplementary data
Journal Articles

Response to Comment on “Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis”

Free
Joanna L. Giles, Ernest Choy, Carmen van den Berg, B. Paul Morgan, Claire L. Harris
Journal: The Journal of Immunology
J Immunol (2015) 195 (1): 4.
https://doi.org/10.4049/jimmunol.1500968
Published: 01 July 2015
View articletitled, Response to Comment on “Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis”
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Journal Articles

Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis

Open Access
Joanna L. Giles, Ernest Choy, Carmen van den Berg, B. Paul Morgan, Claire L. Harris
Journal: The Journal of Immunology
J Immunol (2015) 194 (7): 3029–3034.
https://doi.org/10.4049/jimmunol.1402956
Published: 01 April 2015
View articletitled, Functional Analysis of a Complement Polymorphism (rs17611) Associated with Rheumatoid Arthritis
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Includes: Supplementary data
Journal Articles

A Novel Antibody against Human Factor B that Blocks Formation of the C3bB Proconvertase and Inhibits Complement Activation in Disease Models

Free
Marta Subías, Agustín Tortajada, Sara Gastoldi, Miriam Galbusera, Andrés López-Perrote, Lucia de Juana Lopez, Fernando Ataúlfo González-Fernández, Ana Villegas-Martínez, Mercedes Dominguez, Oscar Llorca, Marina Noris, B. Paul Morgan, Santiago Rodríguez de Córdoba
Journal: The Journal of Immunology
J Immunol (2014) 193 (11): 5567–5575.
https://doi.org/10.4049/jimmunol.1402013
Published: 01 December 2014
View articletitled, A Novel Antibody against Human Factor B that Blocks Formation of the C3bB Proconvertase and Inhibits Complement Activation in Disease Models
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Journal Articles

Identification of Factor H–like Protein 1 as the Predominant Complement Regulator in Bruch’s Membrane: Implications for Age-Related Macular Degeneration

Free
Simon J. Clark, Christoph Q. Schmidt, Anne M. White, Svetlana Hakobyan, B. Paul Morgan, Paul N. Bishop
Journal: The Journal of Immunology
J Immunol (2014) 193 (10): 4962–4970.
https://doi.org/10.4049/jimmunol.1401613
Published: 15 November 2014
View articletitled, Identification of Factor H–like Protein 1 as the Predominant Complement Regulator in Bruch’s Membrane: Implications for Age-Related Macular Degeneration
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Includes: Supplementary data
Journal Articles

A Humanized Antibody That Regulates the Alternative Pathway Convertase: Potential for Therapy of Renal Disease Associated with Nephritic Factors

Free
Danielle Paixão-Cavalcante, Eva Torreira, Margaret A. Lindorfer, Santiago Rodriguez de Cordoba, B. Paul Morgan, Ronald P. Taylor, Oscar Llorca, Claire L. Harris
Journal: The Journal of Immunology
J Immunol (2014) 192 (10): 4844–4851.
https://doi.org/10.4049/jimmunol.1303131
Published: 15 May 2014
View articletitled, A Humanized Antibody That Regulates the Alternative Pathway Convertase: Potential for Therapy of Renal Disease Associated with Nephritic Factors
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Includes: Supplementary data
Journal Articles

Inhibition of the Membrane Attack Complex of the Complement System Reduces Secondary Neuroaxonal Loss and Promotes Neurologic Recovery after Traumatic Brain Injury in Mice

Free
Kees Fluiter, Anne Loes Opperhuizen, B. Paul Morgan, Frank Baas, Valeria Ramaglia
Journal: The Journal of Immunology
J Immunol (2014) 192 (5): 2339–2348.
https://doi.org/10.4049/jimmunol.1302793
Published: 01 March 2014
View articletitled, Inhibition of the Membrane Attack Complex of the Complement System Reduces Secondary Neuroaxonal Loss and Promotes Neurologic Recovery after Traumatic Brain Injury in Mice
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Includes: Supplementary data
Journal Articles

Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

Open Access
Federica Laudisi, Roberto Spreafico, Maximilien Evrard, Timothy R. Hughes, Barbara Mandriani, Matheswaran Kandasamy, B. Paul Morgan, Baalasubramanian Sivasankar, Alessandra Mortellaro
Journal: The Journal of Immunology
J Immunol (2013) 191 (3): 1006–1010.
https://doi.org/10.4049/jimmunol.1300489
Published: 01 August 2013
View articletitled, Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release
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Includes: Supplementary data
Journal Articles

Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions

Free
Simon J. Clark, Liam A. Ridge, Andrew P. Herbert, Svetlana Hakobyan, Barbara Mulloy, Rachel Lennon, Reinhard Würzner, B. Paul Morgan, Dusan Uhrín, Paul N. Bishop, Anthony J. Day
Journal: The Journal of Immunology
J Immunol (2013) 190 (5): 2049–2057.
https://doi.org/10.4049/jimmunol.1201751
Published: 01 March 2013
View articletitled, Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions
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Includes: Supplementary data
Journal Articles

Retraction: Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms

Free
Martin V. Kolev, B. Paul Morgan, Marieta M. Ruseva, Rossen M. Donev
Journal: The Journal of Immunology
J Immunol (2011) 187 (12): 6581.
https://doi.org/10.4049/jimmunol.1190073
Published: 15 December 2011
View articletitled, Retraction: Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms
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Journal Articles

Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms

Free
Martin V. Kolev, Marieta M. Ruseva, B. Paul Morgan, Rossen M. Donev
Journal: The Journal of Immunology
J Immunol (2010) 184 (11): 6035–6042.
https://doi.org/10.4049/jimmunol.1000045
Published: 01 June 2010
View articletitled, Targeting Neural-Restrictive Silencer Factor Sensitizes Tumor Cells to Antibody-Based Cancer Immunotherapy In Vitro via Multiple Mechanisms
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Journal Articles

Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages

Free
Aisleen McColl, Stylianos Bournazos, Sandra Franz, Mauro Perretti, B. Paul Morgan, Christopher Haslett, Ian Dransfield
Journal: The Journal of Immunology
J Immunol (2009) 183 (3): 2167–2175.
https://doi.org/10.4049/jimmunol.0803503
Published: 01 August 2009
View articletitled, Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages
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Journal Articles

Zymosan, but Not Lipopolysaccharide, Triggers Severe and Progressive Peritoneal Injury Accompanied by Complement Activation in a Rat Peritonitis Model

Free
Masashi Mizuno, Yasuhiko Ito, Natalie Hepburn, Tomohiro Mizuno, Yukihiro Noda, Yukio Yuzawa, Claire L. Harris, B. Paul Morgan, Seiichi Matsuo
Journal: The Journal of Immunology
J Immunol (2009) 183 (2): 1403–1412.
https://doi.org/10.4049/jimmunol.0804245
Published: 15 July 2009
View articletitled, Zymosan, but Not Lipopolysaccharide, Triggers Severe and Progressive Peritoneal Injury Accompanied by Complement Activation in a Rat Peritonitis Model
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Journal Articles

CD59 Blockade Enhances Antigen-Specific CD4+ T Cell Responses in Humans: A New Target for Cancer Immunotherapy?

Free
Baalasubramanian Sivasankar, M. Paula Longhi, Kathleen M. E. Gallagher, Gareth J. Betts, B. Paul Morgan, Andrew J. Godkin, Awen M. Gallimore
Journal: The Journal of Immunology
J Immunol (2009) 182 (9): 5203–5207.
https://doi.org/10.4049/jimmunol.0804243
Published: 01 May 2009
View articletitled, CD59 Blockade Enhances Antigen-Specific CD4+ T Cell Responses in Humans: A New Target for Cancer Immunotherapy?
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Journal Articles

CD59, a Complement Regulatory Protein, Controls Choroidal Neovascularization in a Mouse Model of Wet-Type Age-Related Macular Degeneration

Free
Nalini S. Bora, Sankaranarayanan Kaliappan, Purushottam Jha, Qin Xu, Baalasubramanian Sivasankar, Claire L. Harris, B. Paul Morgan, Puran S. Bora
Journal: The Journal of Immunology
J Immunol (2007) 178 (3): 1783–1790.
https://doi.org/10.4049/jimmunol.178.3.1783
Published: 01 February 2007
View articletitled, CD59, a Complement Regulatory Protein, Controls Choroidal Neovascularization in a Mouse Model of Wet-Type Age-Related Macular Degeneration
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Journal Articles

Decay-Accelerating Factor Must Bind Both Components of the Complement Alternative Pathway C3 Convertase to Mediate Efficient Decay

Free
Claire L. Harris, David M. Pettigrew, Susan M. Lea, B. Paul Morgan
Journal: The Journal of Immunology
J Immunol (2007) 178 (1): 352–359.
https://doi.org/10.4049/jimmunol.178.1.352
Published: 01 January 2007
View articletitled, Decay-Accelerating Factor Must Bind Both Components of the Complement Alternative Pathway C3 Convertase to Mediate Efficient Decay
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Journal Articles

Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity

Free
Nader Omidvar, Eddie C. Y. Wang, Paul Brennan, M. Paula Longhi, Richard A. G. Smith, B. Paul Morgan
Journal: The Journal of Immunology
J Immunol (2006) 176 (5): 2915–2923.
https://doi.org/10.4049/jimmunol.176.5.2915
Published: 01 March 2006
View articletitled, Expression of Glycosylphosphatidylinositol-Anchored CD59 on Target Cells Enhances Human NK Cell-Mediated Cytotoxicity
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Journal Articles

Cutting Edge: Murine CD59a Modulates Antiviral CD4+ T Cell Activity in a Complement-Independent Manner

Free
M. Paula Longhi, Baalasubramanian Sivasankar, Nader Omidvar, B. Paul Morgan, Awen Gallimore
Journal: The Journal of Immunology
J Immunol (2005) 175 (11): 7098–7102.
https://doi.org/10.4049/jimmunol.175.11.7098
Published: 01 December 2005
View articletitled, Cutting Edge: Murine CD59a Modulates Antiviral CD4+ T Cell Activity in a Complement-Independent Manner
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