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Bent K. Jakobsen
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Journal Articles

Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β

Jonathan D. Silk, Rachel J. M. Abbott, Katherine J. Adams, Alan D. Bennett, Sara Brett, Terri V. Cornforth, Katherine L. Crossland, David J. Figueroa, Junping Jing, Caitriona O’Connor, Annette Pachnio, Lea Patasic, Carlos E. Peredo, Adriano Quattrini, Laura L. Quinn, Alistair G. Rust, Manoj Saini, Joseph P. Sanderson, Dylan Steiner, Barbara Tavano, Preetha Viswanathan, Guy E. Wiedermann, Ryan Wong, Bent K. Jakobsen, Cedrik M. Britten, Andrew B. Gerry, Joanna E. Brewer
Journal: The Journal of Immunology
J Immunol (2022) 208 (1): 169–180.
https://doi.org/10.4049/jimmunol.2001357
Published: 01 January 2022
View article titled, Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β
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Includes: Supplementary data
Journal Articles

TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide–HLA Complex

Charlotte H. Coles, Rachel M. Mulvaney, Sunir Malla, Andrew Walker, Kathrine J. Smith, Angharad Lloyd, Kate L. Lowe, Michelle L. McCully, Ruth Martinez Hague, Milos Aleksic, Jane Harper, Samantha J. Paston, Zoe Donnellan, Fiona Chester, Katrin Wiederhold, Ross A. Robinson, Andrew Knox, Andrea R. Stacey, Joseph Dukes, Emma Baston, Sue Griffin, Bent K. Jakobsen, Annelise Vuidepot, Stephen Harper
Journal: The Journal of Immunology
J Immunol (2020) 204 (7): 1943–1953.
https://doi.org/10.4049/jimmunol.1900915
Published: 01 April 2020
View article titled, TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide–HLA Complex
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Includes: Supplementary data
Journal Articles

Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions

Paul F. Robbins, Yong F. Li, Mona El-Gamil, Yangbing Zhao, Jennifer A. Wargo, Zhili Zheng, Hui Xu, Richard A. Morgan, Steven A. Feldman, Laura A. Johnson, Alan D. Bennett, Steven M. Dunn, Tara M. Mahon, Bent K. Jakobsen, Steven A. Rosenberg
Journal: The Journal of Immunology
J Immunol (2008) 180 (9): 6116–6131.
https://doi.org/10.4049/jimmunol.180.9.6116
Published: 01 May 2008
View article titled, Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions
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Journal Articles

High-Affinity TCRs Generated by Phage Display Provide CD4+ T Cells with the Ability to Recognize and Kill Tumor Cell Lines

Yangbing Zhao, Alan D. Bennett, Zhili Zheng, Qiong J. Wang, Paul F. Robbins, Lawrence Y. L. Yu, Yi Li, Peter E. Molloy, Steven M. Dunn, Bent K. Jakobsen, Steven A. Rosenberg, Richard A. Morgan
Journal: The Journal of Immunology
J Immunol (2007) 179 (9): 5845–5854.
https://doi.org/10.4049/jimmunol.179.9.5845
Published: 01 November 2007
View article titled, High-Affinity TCRs Generated by Phage Display Provide CD4<sup>+</sup> T Cells with the Ability to Recognize and Kill Tumor Cell Lines
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Journal Articles

Human TCR-Binding Affinity is Governed by MHC Class Restriction

David K. Cole, Nicholas J. Pumphrey, Jonathan M. Boulter, Malkit Sami, John I. Bell, Emma Gostick, David A. Price, George F. Gao, Andrew K. Sewell, Bent K. Jakobsen
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5727–5734.
https://doi.org/10.4049/jimmunol.178.9.5727
Published: 01 May 2007
View article titled, Human TCR-Binding Affinity is Governed by MHC Class Restriction
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Journal Articles

Quantifying and Imaging NY-ESO-1/LAGE-1-Derived Epitopes on Tumor Cells Using High Affinity T Cell Receptors

Marco A. Purbhoo, Deborah H. Sutton, Joanna E. Brewer, Rebecca E. Mullings, Maxine E. Hill, Tara M. Mahon, Julia Karbach, Elke Jäger, Brian J. Cameron, Nikolai Lissin, Paresh Vyas, Ji-Li Chen, Vincenzo Cerundolo, Bent K. Jakobsen
Journal: The Journal of Immunology
J Immunol (2006) 176 (12): 7308–7316.
https://doi.org/10.4049/jimmunol.176.12.7308
Published: 15 June 2006
View article titled, Quantifying and Imaging NY-ESO-1/LAGE-1-Derived Epitopes on Tumor Cells Using High Affinity T Cell Receptors
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Journal Articles

High Avidity Antigen-Specific CTL Identified by CD8-Independent Tetramer Staining

Ed Man-Lik Choi, Ji-Li Chen, Linda Wooldridge, Mariolina Salio, Anna Lissina, Nikolai Lissin, Ian F. Hermans, Jonathan D. Silk, Fareed Mirza, Michael J. Palmowski, P. Rod Dunbar, Bent K. Jakobsen, Andy K. Sewell, Vincenzo Cerundolo
Journal: The Journal of Immunology
J Immunol (2003) 171 (10): 5116–5123.
https://doi.org/10.4049/jimmunol.171.10.5116
Published: 15 November 2003
View article titled, High Avidity Antigen-Specific CTL Identified by CD8-Independent Tetramer Staining
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