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Journal Articles

Time Course scRNAseq Analysis Reveals Mechanisms of Impaired Lung Recovery Post Influenza Infection during Aging: Zooming into Macrophages

Yue Wu, Jinyi Tang, Xiaochen Gao, Chaofan Li, Bibo Zhu, Gislane de Almeida Santos, Harish Narasimhan, Ying Li, Ruixuan Zhang, Cori E. Fain, Katayoun Ayasoufi, Aaron J. Johnson, Haidong Dong, Jie Sun
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 71.24.
https://doi.org/10.4049/jimmunol.210.Supp.71.24
Published: 01 May 2023
View article titled, Time Course scRNAseq Analysis Reveals Mechanisms of Impaired Lung Recovery Post Influenza Infection during Aging: Zooming into Macrophages
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Journal Articles

Time course scRNAseq analysis on host mucosal immune responses to influenza virus infection during aging

Yue Wu, Jinyi Tang, Xiaochen Gao, Chaofan Li, Bibo Zhu, Ruixuan Zhang, Cori Fain, Katayoun Ayasoufi, Aaron J Johnson, Haidong Dong, Jie Sun
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 114.20.
https://doi.org/10.4049/jimmunol.208.Supp.114.20
Published: 01 May 2022
View article titled, Time course scRNAseq analysis on host mucosal immune responses to influenza virus infection during aging
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Journal Articles

Simultaneously targeting hyperinflammation and hyperglycemia following respiratory viral infection

Xiaoqin Wei, Bibo Zhu, Jie Sun
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 125.14.
https://doi.org/10.4049/jimmunol.208.Supp.125.14
Published: 01 May 2022
View article titled, Simultaneously targeting hyperinflammation and hyperglycemia following respiratory viral infection
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Journal Articles

TFAM-Dependent Mitochondrial Metabolism Is Required for Alveolar Macrophage Maintenance and Homeostasis

Xiaochen Gao, Bibo Zhu, Yue Wu, Chaofan Li, Xian Zhou, Jinyi Tang, Jie Sun
Journal: The Journal of Immunology
J Immunol (2022) 208 (6): 1456–1466.
https://doi.org/10.4049/jimmunol.2100741
Published: 15 March 2022
View article titled, TFAM-Dependent Mitochondrial Metabolism Is Required for Alveolar Macrophage Maintenance and Homeostasis
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Includes: Supplementary data
Journal Articles

Zom-biecoming: Single-Cell RNA-seq reveals senescence-like features of alveolar macrophages during aging

Yue Wu, Bibo Zhu, Ruixuan Zhang, Zheng Wang, Nick P. Goplen, Xiaochen Gao, Ying Li, Amber Cadani, Thomas J Braciale, Jie Sun
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 55.06.
https://doi.org/10.4049/jimmunol.206.Supp.55.06
Published: 01 May 2021
View article titled, Zom-biecoming: Single-Cell RNA-seq reveals senescence-like features of alveolar macrophages during aging
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Journal Articles

WNT/β-catenin directed metabolic choice uncouples lung-resident alveolar macrophage inflammatory activity from self-renewal

Bibo Zhu, Yue Wu, Su Huang, Ruixuan Zhang, Chaofan Li, In Su Cheon, Min Wang, Xian Zhou, Quynh Nguyen, Hu Zeng, M. Mark Taketo, Matthias Mack, Virginia Shapiro, Xiaobo Zhou, Ananda Goldrath, Mark H Kaplan, Jie Sun
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 69.6.
https://doi.org/10.4049/jimmunol.204.Supp.69.6
Published: 01 May 2020
View article titled, WNT/β-catenin directed metabolic choice uncouples lung-resident alveolar macrophage inflammatory activity from self-renewal
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Journal Articles

Glutamine metabolism is required for alveolar macrophage proliferation

Min Wang, Bibo Zhu, Jie Sun
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 248.18.
https://doi.org/10.4049/jimmunol.204.Supp.248.18
Published: 01 May 2020
View article titled, Glutamine metabolism is required for alveolar macrophage proliferation
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Journal Articles

Zom-biecoming: Single-Cell RNA-sequencing reveals senescence-like features of alveolar macrophages during aging

Yue Wu, Bibo Zhu, Ruixuan Zhang, Nicholas PJ. Goplen, Zheng Wang, Ying Li, Amber Cardani-Boulton, Thomas J Braciale, Jie Sun
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 235.13.
https://doi.org/10.4049/jimmunol.204.Supp.235.13
Published: 01 May 2020
View article titled, Zom-biecoming: Single-Cell RNA-sequencing reveals senescence-like features of alveolar macrophages during aging
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Journal Articles

Inhibition of effective anti-tumor immunity by macrophage Bcl6

Nidhi Nitin Desai, BIBO ZHU, YoungMin Son, Jie Sun
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 135.28.
https://doi.org/10.4049/jimmunol.202.Supp.135.28
Published: 01 May 2019
View article titled, Inhibition of effective anti-tumor immunity by macrophage Bcl6
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Journal Articles

Single-cell RNA-seq of young and aged alveolar macrophages

Yue Wu, Bibo Zhu, Nick G. Goplen, Ruixuan Zhang, Ying Li, Amber N Cardani, Thomas J Braciale, Jie Sun
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 129.18.
https://doi.org/10.4049/jimmunol.202.Supp.129.18
Published: 01 May 2019
View article titled, Single-cell RNA-seq of young and aged alveolar macrophages
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Journal Articles

BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza infection

Jie Sun, Bibo Zhu
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 74.5.
https://doi.org/10.4049/jimmunol.202.Supp.74.5
Published: 01 May 2019
View article titled, BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza infection
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Journal Articles

BHLHE40 programs mitochondrial regulation of resident CD8+ T cell fitness and functionality

Chaofan Li, BIBO ZHU, YoungMin Son, Zheng Wang, Brian T Edelson, Taro Hitosugi, Jeffrey C Rathmell, Haidong Dong, Jie Sun
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 60.2.
https://doi.org/10.4049/jimmunol.202.Supp.60.2
Published: 01 May 2019
View article titled, BHLHE40 programs mitochondrial regulation of resident CD8<sup>+</sup> T cell fitness and functionality
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Journal Articles

Reciprocal regulation of lung resident alveolar macrophage function and repopulation by β-catenin and PPAR-γ dictates host morbidity and tissue recovery from respiratory viral infection

Bibo Zhu, Su Huang, Li Jiang, Ruixuan Zhang, Jie Sun
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 183.6.
https://doi.org/10.4049/jimmunol.200.Supp.183.6
Published: 01 May 2018
View article titled, Reciprocal regulation of lung resident alveolar macrophage function and repopulation by β-catenin and PPAR-γ dictates host morbidity and tissue recovery from respiratory viral infection
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Journal Articles

Myeloid PPAR-γ suppresses acute host diseases and inhibits chronic fibrosis development following influenza infection

Jie Sun, Su Huang, Bibo Zhu, Li Jiang
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 203.7.
https://doi.org/10.4049/jimmunol.198.Supp.203.7
Published: 01 May 2017
View article titled, Myeloid PPAR-γ suppresses acute host diseases and inhibits chronic fibrosis development following influenza infection
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Journal Articles

MicroRNA-15b Modulates Japanese Encephalitis Virus–Mediated Inflammation via Targeting RNF125

Bibo Zhu, Jing Ye, Yanru Nie, Usama Ashraf, Ali Zohaib, Xiaodong Duan, Zhen F. Fu, Yunfeng Song, Huanchun Chen, Shengbo Cao
Journal: The Journal of Immunology
J Immunol (2015) 195 (5): 2251–2262.
https://doi.org/10.4049/jimmunol.1500370
Published: 01 September 2015
View article titled, MicroRNA-15b Modulates Japanese Encephalitis Virus–Mediated Inflammation via Targeting RNF125
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Includes: Supplementary data