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Brian M. J. Foxwell
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Journal Articles

Nonsteroidal Anti-Inflammatory Drugs Increase TNF Production in Rheumatoid Synovial Membrane Cultures and Whole Blood

Theresa H. Page, Jeremy J. O. Turner, Anthony C. Brown, Emma M. Timms, Julia J. Inglis, Fionula M. Brennan, Brian M. J. Foxwell, Keith P. Ray, Marc Feldmann
Journal: The Journal of Immunology
J Immunol (2010) 185 (6): 3694–3701.
https://doi.org/10.4049/jimmunol.1000906
Published: 15 September 2010
View article titled, Nonsteroidal Anti-Inflammatory Drugs Increase TNF Production in Rheumatoid Synovial Membrane Cultures and Whole Blood
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Includes: Supplementary data
Journal Articles

Cutting Edge: A Transcriptional Repressor and Corepressor Induced by the STAT3-Regulated Anti-Inflammatory Signaling Pathway

Karim C. El Kasmi, Amber M. Smith, Lynn Williams, Geoffrey Neale, Athanasia Panopolous, Stephanie S. Watowich, Hans Häcker, Brian M. J. Foxwell, Peter J. Murray
Journal: The Journal of Immunology
J Immunol (2007) 179 (11): 7215–7219.
https://doi.org/10.4049/jimmunol.179.11.7215
Published: 01 December 2007
View article titled, Cutting Edge: A Transcriptional Repressor and Corepressor Induced by the STAT3-Regulated Anti-Inflammatory Signaling Pathway
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Journal Articles

IL-10 Induces IL-10 in Primary Human Monocyte-Derived Macrophages via the Transcription Factor Stat3

Karl J. Staples, Timothy Smallie, Lynn M. Williams, Andy Foey, Bernie Burke, Brian M. J. Foxwell, Loems Ziegler-Heitbrock
Journal: The Journal of Immunology
J Immunol (2007) 178 (8): 4779–4785.
https://doi.org/10.4049/jimmunol.178.8.4779
Published: 15 April 2007
View article titled, IL-10 Induces IL-10 in Primary Human Monocyte-Derived Macrophages via the Transcription Factor Stat3
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Journal Articles

Bruton’s Tyrosine Kinase Is Required for TLR2 and TLR4-Induced TNF, but Not IL-6, Production

Nicole J. Horwood, Theresa H. Page, John P. McDaid, Christine D. Palmer, Jamie Campbell, Tara Mahon, Fionula M. Brennan, David Webster, Brian M. J. Foxwell
Journal: The Journal of Immunology
J Immunol (2006) 176 (6): 3635–3641.
https://doi.org/10.4049/jimmunol.176.6.3635
Published: 15 March 2006
View article titled, Bruton’s Tyrosine Kinase Is Required for TLR2 and TLR4-Induced TNF, but Not IL-6, Production
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Journal Articles

Inhibition of NF-κB and Oxidative Pathways in Human Dendritic Cells by Antioxidative Vitamins Generates Regulatory T Cells

Peng H. Tan, Pervinder Sagoo, Cliburn Chan, John B. Yates, Jamie Campbell, Sven C. Beutelspacher, Brian M. J. Foxwell, Giovanna Lombardi, Andrew J. T. George
Journal: The Journal of Immunology
J Immunol (2005) 174 (12): 7633–7644.
https://doi.org/10.4049/jimmunol.174.12.7633
Published: 15 June 2005
View article titled, Inhibition of NF-κB and Oxidative Pathways in Human Dendritic Cells by Antioxidative Vitamins Generates Regulatory T Cells
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Journal Articles

A Novel Mechanism for TNF-α Regulation by p38 MAPK: Involvement of NF-κB with Implications for Therapy in Rheumatoid Arthritis

Jamie Campbell, Cathleen J. Ciesielski, Abigail E. Hunt, Nicole J. Horwood, Jonathan T. Beech, Louise A. Hayes, Agnes Denys, Marc Feldmann, Fionula M. Brennan, Brian M. J. Foxwell
Journal: The Journal of Immunology
J Immunol (2004) 173 (11): 6928–6937.
https://doi.org/10.4049/jimmunol.173.11.6928
Published: 01 December 2004
View article titled, A Novel Mechanism for TNF-α Regulation by p38 MAPK: Involvement of NF-κB with Implications for Therapy in Rheumatoid Arthritis
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Journal Articles

A Late, Prolonged Activation of the Phosphatidylinositol 3-Kinase Pathway Is Required for T Cell Proliferation

Ferdinand V. Lali, James Crawley, Derek A. McCulloch, Brian M. J. Foxwell
Journal: The Journal of Immunology
J Immunol (2004) 172 (6): 3527–3534.
https://doi.org/10.4049/jimmunol.172.6.3527
Published: 15 March 2004
View article titled, A Late, Prolonged Activation of the Phosphatidylinositol 3-Kinase Pathway Is Required for T Cell Proliferation
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Journal Articles

Evidence for a Dual Mechanism for IL-10 Suppression of TNF-α Production That Does Not Involve Inhibition of p38 Mitogen-Activated Protein Kinase or NF-κB in Primary Human Macrophages

Agnes Denys, Irina A. Udalova, Clive Smith, Lynn M. Williams, Cathleen J. Ciesielski, Jamie Campbell, Caroline Andrews, Dominic Kwaitkowski, Brian M. J. Foxwell
Journal: The Journal of Immunology
J Immunol (2002) 168 (10): 4837–4845.
https://doi.org/10.4049/jimmunol.168.10.4837
Published: 15 May 2002
View article titled, Evidence for a Dual Mechanism for IL-10 Suppression of TNF-α Production That Does Not Involve Inhibition of p38 Mitogen-Activated Protein Kinase or NF-κB in Primary Human Macrophages
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Journal Articles

NF-κB-Inducing Kinase Is Dispensable for Activation of NF-κB in Inflammatory Settings but Essential for Lymphotoxin β Receptor Activation of NF-κB in Primary Human Fibroblasts

Clive Smith, Evangelos Andreakos, James B. Crawley, Fionula M. Brennan, Marc Feldmann, Brian M. J. Foxwell
Journal: The Journal of Immunology
J Immunol (2001) 167 (10): 5895–5903.
https://doi.org/10.4049/jimmunol.167.10.5895
Published: 15 November 2001
View article titled, NF-κB-Inducing Kinase Is Dispensable for Activation of NF-κB in Inflammatory Settings but Essential for Lymphotoxin β Receptor Activation of NF-κB in Primary Human Fibroblasts
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Journal Articles

Prolonged Exposure of T Cells to TNF Down-Regulates TCRζ and Expression of the TCR/CD3 Complex at the Cell Surface

Pia Isomäki, Manvinder Panesar, Alex Annenkov, Joanna M. Clark, Brian M. J. Foxwell, Yuti Chernajovsky, Andrew P. Cope
Journal: The Journal of Immunology
J Immunol (2001) 166 (9): 5495–5507.
https://doi.org/10.4049/jimmunol.166.9.5495
Published: 01 May 2001
View article titled, Prolonged Exposure of T Cells to TNF Down-Regulates TCRζ and Expression of the TCR/CD3 Complex at the Cell Surface
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Journal Articles

Selective Regulation of Cytokine Induction by Adenoviral Gene Transfer of IκBα into Human Macrophages: Lipopolysaccharide-Induced, But Not Zymosan-Induced, Proinflammatory Cytokines Are Inhibited, But IL-10 Is Nuclear Factor-κB Independent

Jan Bondeson, Kylie A. Browne, Fionula M. Brennan, Brian M. J. Foxwell, Marc Feldmann
Journal: The Journal of Immunology
J Immunol (1999) 162 (5): 2939–2945.
https://doi.org/10.4049/jimmunol.162.5.2939
Published: 01 March 1999
View article titled, Selective Regulation of Cytokine Induction by Adenoviral Gene Transfer of IκBα into Human Macrophages: Lipopolysaccharide-Induced, But Not Zymosan-Induced, Proinflammatory Cytokines Are Inhibited, But IL-10 Is Nuclear Factor-κB Independent
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Journal Articles

Regulation of Monocyte IL-10 Synthesis by Endogenous IL-1 and TNF-α: Role of the p38 and p42/44 Mitogen-Activated Protein Kinases

Andrew D. Foey, Sarah L. Parry, Lynn M. Williams, Marc Feldmann, Brian M. J. Foxwell, Fionula M. Brennan
Journal: The Journal of Immunology
J Immunol (1998) 160 (2): 920–928.
https://doi.org/10.4049/jimmunol.160.2.920
Published: 15 January 1998
View article titled, Regulation of Monocyte IL-10 Synthesis by Endogenous IL-1 and TNF-α: Role of the p38 and p42/44 Mitogen-Activated Protein Kinases
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