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Brian R. Rosborough
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Journal Articles

Single cell RNA sequencing reveals novel inflammatory mechanisms of human acute respiratory distress syndrome

Brian R Rosborough, Jie Chen, Yale Jiang, Georgios Kitsios, Bryan McVerry, Janet S Lee, Anuradha Ray, Wei Chen, Prabir Ray
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 69.19.
https://doi.org/10.4049/jimmunol.204.Supp.69.19
Published: 01 May 2020
View article titled, Single cell RNA sequencing reveals novel inflammatory mechanisms of human acute respiratory distress syndrome
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Journal Articles

A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells

Leo C. Chen, Yawah T. Nicholson, Brian R. Rosborough, Angus W. Thomson, Giorgio Raimondi
Journal: The Journal of Immunology
J Immunol (2016) 197 (4): 1137–1147.
https://doi.org/10.4049/jimmunol.1600696
Published: 15 August 2016
View article titled, A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells
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Includes: Supplementary data
Journal Articles

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo

Dàlia Raïch-Regué, Brian R. Rosborough, Alicia R. Watson, Mandy J. McGeachy, Hēth R. Turnquist, Angus W. Thomson
Journal: The Journal of Immunology
J Immunol (2015) 194 (10): 4767–4776.
https://doi.org/10.4049/jimmunol.1402551
Published: 15 May 2015
View article titled, mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo
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Includes: Supplementary data
Journal Articles

IL-33 Is an Unconventional Alarmin That Stimulates IL-2 Secretion by Dendritic Cells To Selectively Expand IL-33R/ST2+ Regulatory T Cells

Benjamin M. Matta, Jeremy M. Lott, Lisa R. Mathews, Quan Liu, Brian R. Rosborough, Bruce R. Blazar, Hēth R. Turnquist
Journal: The Journal of Immunology
J Immunol (2014) 193 (8): 4010–4020.
https://doi.org/10.4049/jimmunol.1400481
Published: 15 October 2014
View article titled, IL-33 Is an Unconventional Alarmin That Stimulates IL-2 Secretion by Dendritic Cells To Selectively Expand IL-33R/ST2<sup>+</sup> Regulatory T Cells
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Includes: Supplementary data
Journal Articles

Cutting Edge: Flt3 Ligand Mediates STAT3-Independent Expansion but STAT3-Dependent Activation of Myeloid-Derived Suppressor Cells

Brian R. Rosborough, Lisa R. Mathews, Benjamin M. Matta, Quan Liu, Dàlia Raïch-Regué, Angus W. Thomson, Hēth R. Turnquist
Journal: The Journal of Immunology
J Immunol (2014) 192 (8): 3470–3473.
https://doi.org/10.4049/jimmunol.1300058
Published: 15 April 2014
View article titled, Cutting Edge: Flt3 Ligand Mediates STAT3-Independent Expansion but STAT3-Dependent Activation of Myeloid-Derived Suppressor Cells
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Includes: Supplementary data
Journal Articles

Histones Activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury

Hai Huang, Hui-Wei Chen, John Evankovich, Wei Yan, Brian R. Rosborough, Gary W. Nace, Qing Ding, Patricia Loughran, Donna Beer-Stolz, Timothy R. Billiar, Charles T. Esmon, Allan Tsung
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2665–2679.
https://doi.org/10.4049/jimmunol.1202733
Published: 01 September 2013
View article titled, Histones Activate the NLRP3 Inflammasome in Kupffer Cells during Sterile Inflammatory Liver Injury
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Includes: Supplementary data
Journal Articles

IL-27 Production and STAT3-Dependent Upregulation of B7-H1 Mediate Immune Regulatory Functions of Liver Plasmacytoid Dendritic Cells

Benjamin M. Matta, Giorgio Raimondi, Brian R. Rosborough, Tina L. Sumpter, Angus W. Thomson
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5227–5237.
https://doi.org/10.4049/jimmunol.1103382
Published: 01 June 2012
View article titled, IL-27 Production and STAT3-Dependent Upregulation of B7-H1 Mediate Immune Regulatory Functions of Liver Plasmacytoid Dendritic Cells
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Includes: Supplementary data
Journal Articles

IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival

Hēth R. Turnquist, Zhenlin Zhao, Brian R. Rosborough, Quan Liu, Antonino Castellaneta, Kumiko Isse, Zhiliang Wang, Megan Lang, Donna Beer Stolz, Xin Xiao Zheng, A. Jake Demetris, Foo Y. Liew, Kathryn J. Wood, Angus W. Thomson
Journal: The Journal of Immunology
J Immunol (2011) 187 (9): 4598–4610.
https://doi.org/10.4049/jimmunol.1100519
Published: 01 November 2011
View article titled, IL-33 Expands Suppressive CD11b<sup>+</sup> Gr-1<sup>int</sup> and Regulatory T Cells, including ST2L<sup>+</sup> Foxp3<sup>+</sup> Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival
Open the PDF for IL-33 Expands Suppressive CD11b<sup>+</sup> Gr-1<sup>int</sup> and Regulatory T Cells, including ST2L<sup>+</sup> Foxp3<sup>+</sup> Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival in another window
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Includes: Supplementary data