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Bruce D. Freedman
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Journal Articles

Small-molecule probe targeting viral PPxY L-domain inhibits filovirus and arenavirus egress.

Laura I Prugar, John M Dye, Marie Loughran, Jay E Wrobel, Allen B Reitz, Bruce D Freedman, Ronald N Harty, Andrew S Herbert
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 215.10.
https://doi.org/10.4049/jimmunol.196.Supp.215.10
Published: 01 May 2016
View article titled, Small-molecule probe targeting viral PPxY L-domain inhibits filovirus and arenavirus egress.
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Journal Articles

Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase Cγ1 Microcluster Dynamics during T Cell Spreading

Esteban Carrizosa, Timothy S. Gomez, Christine M. Labno, Deborah A. Klos Dehring, Xiaohong Liu, Bruce D. Freedman, Daniel D. Billadeau, Janis K. Burkhardt
Journal: The Journal of Immunology
J Immunol (2009) 183 (11): 7352–7361.
https://doi.org/10.4049/jimmunol.0900973
Published: 01 December 2009
View article titled, Hematopoietic Lineage Cell-Specific Protein 1 Is Recruited to the Immunological Synapse by IL-2-Inducible T Cell Kinase and Regulates Phospholipase Cγ1 Microcluster Dynamics during T Cell Spreading
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Includes: Multimedia, Supplementary data
Journal Articles

HS1 and Itk cooperate to regulate actin remodeling and Ca2+ signaling in T cells (35.28)

Esteban Carrizosa, Timothy S. Gomez, Christine M. Labno, Briana L. Chang, Deborah A. Klos Dehring, Peimin Zhu, Bruce D. Freedman, Daniel D. Billadeau, Janis K. Burkhardt
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 35.28.
https://doi.org/10.4049/jimmunol.182.Supp.35.28
Published: 01 April 2009
View article titled, HS1 and Itk cooperate to regulate actin remodeling and Ca2+ signaling in T cells (35.28)
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Journal Articles

Ezrin and Moesin Function Together to Promote T Cell Activation

Meredith H. Shaffer, Renell S. Dupree, Peimin Zhu, Ichiko Saotome, Richard F. Schmidt, Andrea I. McClatchey, Bruce D. Freedman, Janis K. Burkhardt
Journal: The Journal of Immunology
J Immunol (2009) 182 (2): 1021–1032.
https://doi.org/10.4049/jimmunol.182.2.1021
Published: 15 January 2009
View article titled, Ezrin and Moesin Function Together to Promote T Cell Activation
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Journal Articles

Adhesion- and Degranulation-Promoting Adapter Protein Is Required for Efficient Thymocyte Development and Selection

Jennifer N. Wu, Shereen Gheith, Natalie A. Bezman, Qing-Hua Liu, Lindsey V. Fostel, Andrew M. Swanson, Bruce D. Freedman, Gary A. Koretzky, Erik J. Peterson
Journal: The Journal of Immunology
J Immunol (2006) 176 (11): 6681–6689.
https://doi.org/10.4049/jimmunol.176.11.6681
Published: 01 June 2006
View article titled, Adhesion- and Degranulation-Promoting Adapter Protein Is Required for Efficient Thymocyte Development and Selection
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Journal Articles

Developmental Alterations in Thymocyte Sensitivity Are Actively Regulated by MHC Class II Expression in the Thymic Medulla

Steven C. Eck, Peimin Zhu, Marion Pepper, Steven J. Bensinger, Bruce D. Freedman, Terri M. Laufer
Journal: The Journal of Immunology
J Immunol (2006) 176 (4): 2229–2237.
https://doi.org/10.4049/jimmunol.176.4.2229
Published: 15 February 2006
View article titled, Developmental Alterations in Thymocyte Sensitivity Are Actively Regulated by MHC Class II Expression in the Thymic Medulla
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Journal Articles

Mechanisms of Hypotonicity-Induced Calcium Signaling and Integrin Activation by Arachidonic Acid-Derived Inflammatory Mediators in B Cells

Peimin Zhu, Xiaohong Liu, Edward F. Labelle, Bruce D. Freedman
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 4981–4989.
https://doi.org/10.4049/jimmunol.175.8.4981
Published: 15 October 2005
View article titled, Mechanisms of Hypotonicity-Induced Calcium Signaling and Integrin Activation by Arachidonic Acid-Derived Inflammatory Mediators in B Cells
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Journal Articles

Distinct Calcium Channels Regulate Responses of Primary B Lymphocytes to B Cell Receptor Engagement and Mechanical Stimuli

Qing-Hua Liu, Xiaohong Liu, Zhiyun Wen, Brian Hondowicz, Leslie King, John Monroe, Bruce D. Freedman
Journal: The Journal of Immunology
J Immunol (2005) 174 (1): 68–79.
https://doi.org/10.4049/jimmunol.174.1.68
Published: 01 January 2005
View article titled, Distinct Calcium Channels Regulate Responses of Primary B Lymphocytes to B Cell Receptor Engagement and Mechanical Stimuli
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Journal Articles

Regulation of T Cell Activation and Tolerance by Phospholipase Cγ-1-Dependent Integrin Avidity Modulation

Andrew D. Wells, Qing-Hua Liu, Brian Hondowicz, Jidong Zhang, Laurence A. Turka, Bruce D. Freedman
Journal: The Journal of Immunology
J Immunol (2003) 170 (8): 4127–4133.
https://doi.org/10.4049/jimmunol.170.8.4127
Published: 15 April 2003
View article titled, Regulation of T Cell Activation and Tolerance by Phospholipase Cγ-1-Dependent Integrin Avidity Modulation
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