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Bruce S. Klein
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Journal Articles

Vaccination with O-linked Mannans Protects against Systemic Candidiasis through Innate Lymphocyte Populations

Cleison Ledesma Taira, Lucas dos Santos Dias, Sarah Lichtenberger, Alexander J. Whitehead, Brenda Kischkel, Mihai G. Netea, Bruce S. Klein, Marcel Wüthrich
Journal: The Journal of Immunology
J Immunol (2024) 213 (6): 843–852.
https://doi.org/10.4049/jimmunol.2400065
Published: 07 August 2024
View article titled, Vaccination with O-linked Mannans Protects against Systemic Candidiasis through Innate Lymphocyte Populations
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Includes: Supplementary data
Journal Articles

Sensitization with Fungal Protease Allergen Establishes Long-Lived, Allergenic Th Cell Memory in the Lung

Abigail Shapiro, Nicolas W. S. Caballes, Rebecca N. Vera, Bruce S. Klein, Paul J. Brennan, Yen-Fei Wu, Darin L. Wiesner
Journal: The Journal of Immunology
J Immunol (2024) 212 (9): 1420–1427.
https://doi.org/10.4049/jimmunol.2300694
Published: 15 March 2024
View article titled, Sensitization with Fungal Protease Allergen Establishes Long-Lived, Allergenic Th Cell Memory in the Lung
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Includes: Supplementary data
Journal Articles

SLAMF1 Is Dispensable for Vaccine-Induced T Cell Development but Required for Resistance to Fungal Infection

Elaine M. Kohn, Lucas dos Santos Dias, Hannah E. Dobson, Xin He, Huafeng Wang, Bruce S. Klein, Marcel Wüthrich
Journal: The Journal of Immunology
J Immunol (2022) 208 (6): 1417–1423.
https://doi.org/10.4049/jimmunol.2100819
Published: 15 March 2022
View article titled, SLAMF1 Is Dispensable for Vaccine-Induced T Cell Development but Required for Resistance to Fungal Infection
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Includes: Supplementary data
Journal Articles

CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection

Althea Campuzano, Hao Zhang, Gary R. Ostroff, Lucas dos Santos Dias, Marcel Wüthrich, Bruce S. Klein, Jieh-Juen Yu, Humberto H. Lara, Jose L. Lopez-Ribot, Chiung-Yu Hung
Journal: The Journal of Immunology
J Immunol (2020) 204 (12): 3296–3306.
https://doi.org/10.4049/jimmunol.1900793
Published: 15 June 2020
View article titled, CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against <em>Coccidioides posadasii</em> Infection
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Includes: Supplementary data
Journal Articles

Defining the signaling and downstream regulation of neutrophil-dendritic cell development for adjunctive therapy

Michael Gui, J. Scott Fites, David Sykes, Michael K Mansour, Bruce S Klein
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 70.19.
https://doi.org/10.4049/jimmunol.202.Supp.70.19
Published: 01 May 2019
View article titled, Defining the signaling and downstream regulation of neutrophil-dendritic cell development for adjunctive therapy
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Journal Articles

CBLB Constrains Inactivated Vaccine-Induced CD8+ T Cell Responses and Immunity against Lethal Fungal Pneumonia

Somashekarappa Gowda Nanjappa, Srinivasu Mudalagiriyappa, J. Scott Fites, M. Suresh, Bruce S Klein
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 190.17.
https://doi.org/10.4049/jimmunol.202.Supp.190.17
Published: 01 May 2019
View article titled, CBLB Constrains Inactivated Vaccine-Induced CD8<sup>+</sup> T Cell Responses and Immunity against Lethal Fungal Pneumonia
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Journal Articles

LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To Activate IFN-γ Release by Innate T Lymphocytes

Akshat Sharma, Stephanie M. Lawry, Bruce S. Klein, Xiaohua Wang, Nathan M. Sherer, Nicholas A. Zumwalde, Jenny E. Gumperz
Journal: The Journal of Immunology
J Immunol (2018) 201 (8): 2452–2461.
https://doi.org/10.4049/jimmunol.1800537
Published: 15 October 2018
View article titled, LFA-1 Ligation by High-Density ICAM-1 Is Sufficient To Activate IFN-γ Release by Innate T Lymphocytes
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Includes: Supplementary data
Journal Articles

CBLB Constrains Inactivated Vaccine–Induced CD8+ T Cell Responses and Immunity against Lethal Fungal Pneumonia

Som G. Nanjappa, Srinivasu Mudalagiriyappa, J. Scott Fites, M. Suresh, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2018) 201 (6): 1717–1726.
https://doi.org/10.4049/jimmunol.1701241
Published: 15 September 2018
View article titled, CBLB Constrains Inactivated Vaccine–Induced CD8<sup>+</sup> T Cell Responses and Immunity against Lethal Fungal Pneumonia
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Includes: Supplementary data
Journal Articles

The Unappreciated Intracellular Lifestyle of Blastomyces dermatitidis

Alana K. Sterkel, Robert Mettelman, Marcel Wüthrich, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2015) 194 (4): 1796–1805.
https://doi.org/10.4049/jimmunol.1303089
Published: 15 February 2015
View article titled, The Unappreciated Intracellular Lifestyle of <em>Blastomyces dermatitidis</em>
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Includes: Multimedia, Supplementary data
Journal Articles

C-Type Lectin Receptors Differentially Induce Th17 Cells and Vaccine Immunity to the Endemic Mycosis of North America

Huafeng Wang, Vanessa LeBert, Chiung Yu Hung, Kevin Galles, Shinobu Saijo, Xin Lin, Garry T. Cole, Bruce S. Klein, Marcel Wüthrich
Journal: The Journal of Immunology
J Immunol (2014) 192 (3): 1107–1119.
https://doi.org/10.4049/jimmunol.1302314
Published: 01 February 2014
View article titled, C-Type Lectin Receptors Differentially Induce Th17 Cells and Vaccine Immunity to the Endemic Mycosis of North America
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Includes: Supplementary data
Journal Articles

Chitin Elicits CCL2 from Airway Epithelial Cells and Induces CCR2-Dependent Innate Allergic Inflammation in the Lung

René M. Roy, Marcel Wüthrich, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2012) 189 (5): 2545–2552.
https://doi.org/10.4049/jimmunol.1200689
Published: 01 September 2012
View article titled, Chitin Elicits CCL2 from Airway Epithelial Cells and Induces CCR2-Dependent Innate Allergic Inflammation in the Lung
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Journal Articles

A TCR Transgenic Mouse Reactive with Multiple Systemic Dimorphic Fungi

Marcel Wüthrich, Chiung Yu Hung, Ben H. Gern, John C. Pick-Jacobs, Kevin J. Galles, Hanna I. Filutowicz, Garry T. Cole, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2011) 187 (3): 1421–1431.
https://doi.org/10.4049/jimmunol.1100921
Published: 01 August 2011
View article titled, A TCR Transgenic Mouse Reactive with Multiple Systemic Dimorphic Fungi
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Journal Articles

Differential Requirements of T Cell Subsets for CD40 Costimulation in Immunity to Blastomyces dermatitidis

Marcel Wüthrich, Phil L. Fisette, Hanna I. Filutowicz, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2006) 176 (9): 5538–5547.
https://doi.org/10.4049/jimmunol.176.9.5538
Published: 01 May 2006
View article titled, Differential Requirements of T Cell Subsets for CD40 Costimulation in Immunity to <em>Blastomyces dermatitidis</em>
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Journal Articles

IL-12 Is Required for Induction but Not Maintenance of Protective, Memory Responses to Blastomyces dermatitidis: Implications for Vaccine Development in Immune-Deficient Hosts

Marcel Wüthrich, Tom Warner, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 5288–5297.
https://doi.org/10.4049/jimmunol.175.8.5288
Published: 15 October 2005
View article titled, IL-12 Is Required for Induction but Not Maintenance of Protective, Memory Responses to <em>Blastomyces dermatitidis</em>: Implications for Vaccine Development in Immune-Deficient Hosts
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Journal Articles

Exploiting Type 3 Complement Receptor for TNF-α Suppression, Immune Evasion, and Progressive Pulmonary Fungal Infection

T. Tristan Brandhorst, Marcel Wüthrich, Bea Finkel-Jimenez, Thomas Warner, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2004) 173 (12): 7444–7453.
https://doi.org/10.4049/jimmunol.173.12.7444
Published: 15 December 2004
View article titled, Exploiting Type 3 Complement Receptor for TNF-α Suppression, Immune Evasion, and Progressive Pulmonary Fungal Infection
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Journal Articles

Requisite Elements in Vaccine Immunity to Blastomyces dermatitidis: Plasticity Uncovers Vaccine Potential in Immune-Deficient Hosts

Marcel Wüthrich, Hanna I. Filutowicz, Tom Warner, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2002) 169 (12): 6969–6976.
https://doi.org/10.4049/jimmunol.169.12.6969
Published: 15 December 2002
View article titled, Requisite Elements in Vaccine Immunity to <em>Blastomyces dermatitidis</em>: Plasticity Uncovers Vaccine Potential in Immune-Deficient Hosts
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Journal Articles

BAD1, an Essential Virulence Factor of Blastomyces dermatitidis, Suppresses Host TNF-α Production Through TGF-β-Dependent and -Independent Mechanisms

Beatriz Finkel-Jimenez, Marcel Wüthrich, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2002) 168 (11): 5746–5755.
https://doi.org/10.4049/jimmunol.168.11.5746
Published: 01 June 2002
View article titled, BAD1, an Essential Virulence Factor of <em>Blastomyces dermatitidis</em>, Suppresses Host TNF-α Production Through TGF-β-Dependent and -Independent Mechanisms
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Journal Articles

The WI-1 Adhesin Blocks Phagocyte TNF-α Production, Imparting Pathogenicity on Blastomyces dermatitidis

Bea Finkel-Jimenez, Marcel Wüthrich, Tristan Brandhorst, Bruce S. Klein
Journal: The Journal of Immunology
J Immunol (2001) 166 (4): 2665–2673.
https://doi.org/10.4049/jimmunol.166.4.2665
Published: 15 February 2001
View article titled, The WI-1 Adhesin Blocks Phagocyte TNF-α Production, Imparting Pathogenicity on <em>Blastomyces dermatitidis</em>
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