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Bruno Kyewski
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Journal Articles

Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation

Chloé Michel, Corey N. Miller, Rita Küchler, Benedikt Brors, Mark S. Anderson, Bruno Kyewski, Sheena Pinto
Journal: The Journal of Immunology
J Immunol (2017) 199 (10): 3488–3503.
https://doi.org/10.4049/jimmunol.1700203
Published: 15 November 2017
View article titled, Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation
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Includes: Supplementary data
Journal Articles

Thymic expression of tissue-restricted self-antigens is a highly coordinated and evolutionary conserved process

Kristin Rattay, Hannah Verena Meyer, Philip Brennecke, Alejandro Reyes, Sheena Pinto, Benedikt Brors, Wolfgang Huber, Lars Steinmetz, Bruno Kyewski
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 186.15.
https://doi.org/10.4049/jimmunol.196.Supp.186.15
Published: 01 May 2016
View article titled, Thymic expression of tissue-restricted self-antigens is a highly coordinated and evolutionary conserved process
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Journal Articles

The role of bone marrow promiscuous gene expression in peripheral tolerance

Chih-Yeh Chen, Michelle Klein, Felix Klug, Sheena Pinto, Bruno Kyewski, Philipp Beckhove
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 55.28.
https://doi.org/10.4049/jimmunol.196.Supp.55.28
Published: 01 May 2016
View article titled, The role of bone marrow promiscuous gene expression in peripheral tolerance
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Journal Articles

Pillars Article: Promiscuous Gene Expression in Medullary Thymic Epithelial Cells Mirrors the Peripheral Self. Nat. Immunol. 2001. 2: 1032–1039

Jens Derbinski, Antje Schulte, Bruno Kyewski, Ludger Klein
Journal: The Journal of Immunology
J Immunol (2016) 196 (7): 2915–2922.
Published: 01 April 2016
View article titled, Pillars Article: Promiscuous Gene Expression in Medullary Thymic Epithelial Cells Mirrors the Peripheral Self. Nat. Immunol. 2001. 2: 1032–1039
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Journal Articles

Thymic Epithelial Cells Are a Nonredundant Source of Wnt Ligands for Thymus Development

Fabian Brunk, Iris Augustin, Michael Meister, Michael Boutros, Bruno Kyewski
Journal: The Journal of Immunology
J Immunol (2015) 195 (11): 5261–5271.
https://doi.org/10.4049/jimmunol.1501265
Published: 01 December 2015
View article titled, Thymic Epithelial Cells Are a Nonredundant Source of Wnt Ligands for Thymus Development
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Includes: Supplementary data
Journal Articles

Homeodomain-Interacting Protein Kinase 2, a Novel Autoimmune Regulator Interaction Partner, Modulates Promiscuous Gene Expression in Medullary Thymic Epithelial Cells

Kristin Rattay, Janine Claude, Esmail Rezavandy, Sonja Matt, Thomas G. Hofmann, Bruno Kyewski, Jens Derbinski
Journal: The Journal of Immunology
J Immunol (2015) 194 (3): 921–928.
https://doi.org/10.4049/jimmunol.1402694
Published: 01 February 2015
View article titled, Homeodomain-Interacting Protein Kinase 2, a Novel Autoimmune Regulator Interaction Partner, Modulates Promiscuous Gene Expression in Medullary Thymic Epithelial Cells
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Includes: Supplementary data
Journal Articles

An Organotypic Coculture Model Supporting Proliferation and Differentiation of Medullary Thymic Epithelial Cells and Promiscuous Gene Expression

Sheena Pinto, Katrin Schmidt, Stefanie Egle, Hans-Jürgen Stark, Petra Boukamp, Bruno Kyewski
Journal: The Journal of Immunology
J Immunol (2013) 190 (3): 1085–1093.
https://doi.org/10.4049/jimmunol.1201843
Published: 01 February 2013
View article titled, An Organotypic Coculture Model Supporting Proliferation and Differentiation of Medullary Thymic Epithelial Cells and Promiscuous Gene Expression
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Journal Articles

How does the age-dependent loss of central tolerance relate to the regulation of ectopic gene expression? (69.6)

Chloe Michel, Bruno Kyewski
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 69.6.
https://doi.org/10.4049/jimmunol.188.Supp.69.6
Published: 01 May 2012
View article titled, How does the age-dependent loss of central tolerance relate to the regulation of ectopic gene expression? (69.6)
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Journal Articles

Increase of T Lymphocyte Self-Reactivity in Aging Inbred Rats: In Vitro Studies with a Model of Experimental Autoimmune Orchitis

Bruno Kyewski, Hartmut Wekerle
Journal: The Journal of Immunology
J Immunol (1978) 120 (4): 1249–1255.
https://doi.org/10.4049/jimmunol.120.4.1249
Published: 01 April 1978
View article titled, Increase of T Lymphocyte Self-Reactivity in Aging Inbred Rats: <em>In Vitro</em> Studies with a Model of Experimental Autoimmune Orchitis
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