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Journal Articles

Cross-neutralizing antibody recognition of sarbecoviruses

Hejun Liu, Meng Yuan, Chang-Chun D. Lee, Nicholas C. Wu, Ian A. Wilson
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 114.02.
DOI: https://doi.org/10.4049/jimmunol.206.Supp.114.02
Published: 01 May 2021
View article titled, Cross-neutralizing antibody recognition of sarbecoviruses
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Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462–469

J. Sayos, C. Wu, M. Morra, N. Wang, X. Zhang, D. Allen, S. van Schaik, L. Notarangelo, R. Geha, M. G. Roncarolo, H. Oettgen, J. E. De Vries, G. Aversa, C. Terhorst
Journal: The Journal of Immunology
J Immunol (2017) 199 (5): 1534–1541.
Published: 01 September 2017
View article titled, Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462–469
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Selective inhibition of NF-kB inducing kinase (NIK) is therapeutically efficacious in IFNα-accelerated lupus nephritis prone mice

Hans D Brightbill, Eric Suto, Nicole Blaquiere, Nandhini Ramamoorthi, Swathi Sujatha-Bhaskar, Emily Gogol, Georgette Castanedo, Benjamin Jackson, Susan Haller, Justin Lesch, Karin Bents, Christine Everett, Pawan Bir Kohli, Sandra Linge, Laura Christian, Kathy Barrett, Allan Jaochico, Leonid M Berezhkovskiy, Peter W Fan, Kelli Veliz, Michael Townsend, Jason DeVoss, Adam Johnson, Robert Godemann, Wyne P Lee, Cary D Austin, Brent McKenzie, Jason A Hackney, James J Crawford, Steven Staben, Moulay Hicham Alaoui Ismaili, Lawren C Wu, Nico Ghilardi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 217.4.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.217.4
Published: 01 May 2017
View article titled, Selective inhibition of NF-kB inducing kinase (NIK) is therapeutically efficacious in IFNα-accelerated lupus nephritis prone mice
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A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma

Aarti Shikotra, David F. Choy, Salman Siddiqui, Greer Arthur, Deepti R. Nagarkar, Guiquan Jia, Adam K. A. Wright, Chandra M. Ohri, Emma Doran, Claire A. Butler, Beverley Hargadon, Alexander R. Abbas, Janet Jackman, Lawren C. Wu, Liam G. Heaney, Joseph R. Arron, Peter Bradding
Journal: The Journal of Immunology
J Immunol (2017) 198 (8): 3307–3317.
DOI: https://doi.org/10.4049/jimmunol.1600606
Published: 15 April 2017
View article titled, A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma
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Includes: Supplementary data
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Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation

Hans D. Brightbill, Janet K. Jackman, Eric Suto, Heather Kennedy, Charles Jones, III, Sreedevi Chalasani, Zhonghua Lin, Lucinda Tam, Meron Roose-Girma, Mercedesz Balazs, Cary D. Austin, Wyne P. Lee, Lawren C. Wu
Journal: The Journal of Immunology
J Immunol (2015) 195 (3): 953–964.
DOI: https://doi.org/10.4049/jimmunol.1401514
Published: 01 August 2015
View article titled, Conditional Deletion of NF-κB–Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation
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Includes: Supplementary data
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Enhancement of Tumor-Specific T Cell–Mediated Immunity in Dendritic Cell–Based Vaccines by Mycobacterium tuberculosis Heat Shock Protein X

In Duk Jung, Sung Jae Shin, Min-Goo Lee, Tae Heung Kang, Hee Dong Han, Seung Jun Lee, Woo Sik Kim, Hong Min Kim, Won Sun Park, Han Wool Kim, Cheol-Heui Yun, Eun Kyung Lee, T.-C. Wu, Yeong-Min Park
Journal: The Journal of Immunology
J Immunol (2014) 193 (3): 1233–1245.
DOI: https://doi.org/10.4049/jimmunol.1400656
Published: 01 August 2014
View article titled, Enhancement of Tumor-Specific T Cell–Mediated Immunity in Dendritic Cell–Based Vaccines by Mycobacterium tuberculosis Heat Shock Protein X
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Includes: Supplementary data
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Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts

Sanjay Chandriani, Daryle J. DePianto, Elsa N. N’Diaye, Alexander R. Abbas, Janet Jackman, Jack Bevers, III, Vladimir Ramirez-Carrozzi, Rajita Pappu, Steven E. Kauder, Karen Toy, Connie Ha, Zora Modrusan, Lawren C. Wu, Harold R. Collard, Paul J. Wolters, Jackson G. Egen, Joseph R. Arron
Journal: The Journal of Immunology
J Immunol (2014) 193 (1): 111–119.
DOI: https://doi.org/10.4049/jimmunol.1301761
Published: 01 July 2014
View article titled, Endogenously Expressed IL-13Rα2 Attenuates IL-13–Mediated Responses but Does Not Activate Signaling in Human Lung Fibroblasts
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Includes: Supplementary data
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Developing an antibody targeting CεmX of mIgE for the treatment of allergic and other IgE-mediated diseases (VAC6P.954)

Yueh-Hsuan Chan, Yu-Tzu Lee, Hung-Wen Chou, Pheidias C Wu, Jiun-Bo Chen, Chau-Hong Li, Tien-Tien Cheng, Nien-Yi Chen, Ko-Haung Lue, Tse-Wen Chang
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 140.15.
DOI: https://doi.org/10.4049/jimmunol.192.Supp.140.15
Published: 01 May 2014
View article titled, Developing an antibody targeting CεmX of mIgE for the treatment of allergic and other IgE-mediated diseases (VAC6P.954)
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A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors

Sue J. Sohn, Kathy Barrett, Anne Van Abbema, Christine Chang, Pawan Bir Kohli, Hidenobu Kanda, Janice Smith, Yingjie Lai, Aihe Zhou, Birong Zhang, Wenqian Yang, Karen Williams, Calum Macleod, Christopher A. Hurley, Janusz J. Kulagowski, Nicholas Lewin-Koh, Hart S. Dengler, Adam R. Johnson, Nico Ghilardi, Mark Zak, Jun Liang, Wade S. Blair, Steven Magnuson, Lawren C. Wu
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2205–2216.
DOI: https://doi.org/10.4049/jimmunol.1202859
Published: 01 September 2013
View article titled, A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors
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Includes: Supplementary data
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Antibodies binding to discrete segments of CϵmX of mIgE on B lymphocytes (P6004)

Yueh-Hsuan Chan, Hsing-Mao Chu, Jiun-Bo Chen, C. Wu, Chi-Chun Pan, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 59.3.
DOI: https://doi.org/10.4049/jimmunol.190.Supp.59.3
Published: 01 May 2013
View article titled, Antibodies binding to discrete segments of CϵmX of mIgE on B lymphocytes (P6004)
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Structural analysis of epitopes recognized by two anti-CϵmX mAbs reveals intrinsic disorder of the CϵmX domain (P6002)

Hsing-Mao Chu, Jon Wright, Yueh-Hsuan Chan, Pheidias C. Wu, Carmay Lim, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 59.2.
DOI: https://doi.org/10.4049/jimmunol.190.Supp.59.2
Published: 01 May 2013
View article titled, Structural analysis of epitopes recognized by two anti-CϵmX mAbs reveals intrinsic disorder of the CϵmX domain (P6002)
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Immune Mechanism of the Antitumor Effects Generated by Bortezomib

Chih-Long Chang, Yun-Ting Hsu, Chao-Chih Wu, Yuh-Cheng Yang, Connie Wang, T.-C. Wu, Chien-Fu Hung
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 3209–3220.
DOI: https://doi.org/10.4049/jimmunol.1103826
Published: 15 September 2012
View article titled, Immune Mechanism of the Antitumor Effects Generated by Bortezomib
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Includes: Supplementary data
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CϵmX peptide-carrying HBcAg virus-like particles induced antibodies that down-regulate mIgE-B cells (53.7)

Chien-Jen Lin, Nien-Yi Nien-Yi Chen, Jiun-Bo Chen, Chien-Sheng Lu, Alfur Fu-Hsin Hung, Yu-Yu Shiung, Pheidias C. Wu, Rong-Long Pan, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 53.7.
DOI: https://doi.org/10.4049/jimmunol.188.Supp.53.7
Published: 01 May 2012
View article titled, CϵmX peptide-carrying HBcAg virus-like particles induced antibodies that down-regulate mIgE-B cells (53.7)
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Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways

David F. Choy, Barmak Modrek, Alexander R. Abbas, Sarah Kummerfeld, Hilary F. Clark, Lawren C. Wu, Grazyna Fedorowicz, Zora Modrusan, John V. Fahy, Prescott G. Woodruff, Joseph R. Arron
Journal: The Journal of Immunology
J Immunol (2011) 186 (3): 1861–1869.
DOI: https://doi.org/10.4049/jimmunol.1002568
Published: 01 February 2011
View article titled, Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways
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Includes: Supplementary data
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Vascular Disrupting Agent, DMXAA, Enhances Therapeutic HPV Vaccine-Induced CTL responses and Antitumor Effects (101.37)

Qi Zeng, Shiwen Peng, Archana Monie, Chien-Fu Hung, T.-c Wu
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 101.37.
DOI: https://doi.org/10.4049/jimmunol.184.Supp.101.37
Published: 01 April 2010
View article titled, Vascular Disrupting Agent, DMXAA, Enhances Therapeutic HPV Vaccine-Induced CTL responses and Antitumor Effects (101.37)
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Unique Epitopes on CεmX in IgE–B Cell Receptors Are Potentially Applicable for Targeting IgE-Committed B Cells

Jiun-Bo Chen, Pheidias C. Wu, Alfur Fu-Hsin Hung, Chia-Yu Chu, Tsen-Fang Tsai, Hui-Ming Yu, Hwan-You Chang, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2010) 184 (4): 1748–1756.
DOI: https://doi.org/10.4049/jimmunol.0902437
Published: 18 January 2010
View article titled, Unique Epitopes on CεmX in IgE–B Cell Receptors Are Potentially Applicable for Targeting IgE-Committed B Cells
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Includes: Supplementary data
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Anti-CmεX monoclonal antibodies potentially applicable for targeting mIgE-expressing B cells (140.20)

Jiun-Bo Chen, Pheidias C. Wu, Alfur Fu-Hsin Hung, Hui-Ming Yu, Tse Wen Chang
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 140.20.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.140.20
Published: 01 April 2009
View article titled, Anti-CmεX monoclonal antibodies potentially applicable for targeting mIgE-expressing B cells (140.20)
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Reduction of serum IgE by depletion of the IgE B cell lineage - a novel approach for the treatment of allergic diseases (140.7)

Lawren C Wu, Hans D Brightbill, Surinder Jeet, Zhonghua Lin, Donghong Yan, Meijuan Zhou, Martha Tan, Allen Nguyen, Sherry Yeh, Donnie Delarosa, Steven R Leong, Terence Wong, Yvonne Chen, Janet Jackman, Mark S Dennis, Anan Chuntharapai, Laura DeForge, Y Gloria Meng, Min Xu, Wyne P Lee, Canio J Refino, Mercedesz Balazs
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 140.7.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.140.7
Published: 01 April 2009
View article titled, Reduction of serum IgE by depletion of the IgE B cell lineage - a novel approach for the treatment of allergic diseases (140.7)
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Inhibition of Tumor Growth by NK1.1+ Cells and CD8+ T Cells Activated by IL-15 through Receptor β/Common γ Signaling in trans

Jesse Rowley, Archana Monie, Chien-Fu Hung, T.-C. Wu
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8237–8247.
DOI: https://doi.org/10.4049/jimmunol.181.12.8237
Published: 15 December 2008
View article titled, Inhibition of Tumor Growth by NK1.1<sup>+</sup> Cells and CD8<sup>+</sup> T Cells Activated by IL-15 through Receptor β/Common γ Signaling in trans
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Enhancement of DNA Vaccine Potency through Coadministration of CIITA DNA with DNA Vaccines via Gene Gun

Daejin Kim, Talia Hoory, Archana Monie, Jenny Pan-Yun Ting, Chien-Fu Hung, T.-C. Wu
Journal: The Journal of Immunology
J Immunol (2008) 180 (10): 7019–7027.
DOI: https://doi.org/10.4049/jimmunol.180.10.7019
Published: 15 May 2008
View article titled, Enhancement of DNA Vaccine Potency through Coadministration of CIITA DNA with DNA Vaccines via Gene Gun
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