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Christine A. Biron
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Journal Articles

mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function

Raymond P. Donnelly, Róisín M. Loftus, Sinéad E. Keating, Kevin T. Liou, Christine A. Biron, Clair M. Gardiner, David K. Finlay
Journal: The Journal of Immunology
J Immunol (2014) 193 (9): 4477–4484.
https://doi.org/10.4049/jimmunol.1401558
Published: 01 November 2014
View article titled, mTORC1-Dependent Metabolic Reprogramming Is a Prerequisite for NK Cell Effector Function
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Includes: Supplementary data
Journal Articles

Proliferation Conditions Promote Intrinsic Changes in NK Cells for an IL-10 Response

Margarite L. Tarrio, Seung-Hwan Lee, Maria F. Fragoso, Hong-Wei Sun, Yuka Kanno, John J. O’Shea, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2014) 193 (1): 354–363.
https://doi.org/10.4049/jimmunol.1302999
Published: 01 July 2014
View article titled, Proliferation Conditions Promote Intrinsic Changes in NK Cells for an IL-10 Response
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Includes: Supplementary data
Journal Articles

Cutting Edge: A Novel Mechanism Bridging Innate and Adaptive Immunity: IL-12 Induction of CD25 To Form High-Affinity IL-2 Receptors on NK Cells

Seung-Hwan Lee, Maria F. Fragoso, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 2712–2716.
https://doi.org/10.4049/jimmunol.1201528
Published: 15 September 2012
View article titled, Cutting Edge: A Novel Mechanism Bridging Innate and Adaptive Immunity: IL-12 Induction of CD25 To Form High-Affinity IL-2 Receptors on NK Cells
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Journal Articles

An activating receptor's critical role in supporting NK cell proliferation for survival during viral infections (44.2)

Seung-Hwan Lee, Kwang-Sin Kim, Nassima Fodil-Cornu, Silvia M Vidal, Christine A Biron
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 44.2.
https://doi.org/10.4049/jimmunol.182.Supp.44.2
Published: 01 April 2009
View article titled, An activating receptor's critical role in supporting NK cell proliferation for survival during viral infections (44.2)
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Journal Articles

Ly49h-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex

Nassima Fodil-Cornu, Seung-Hwan Lee, Simon Belanger, Andrew P. Makrigiannis, Christine A. Biron, R. Mark Buller, Silvia M. Vidal
Journal: The Journal of Immunology
J Immunol (2008) 181 (9): 6394–6405.
https://doi.org/10.4049/jimmunol.181.9.6394
Published: 01 November 2008
View article titled, <em>Ly49h</em>-Deficient C57BL/6 Mice: A New Mouse Cytomegalovirus-Susceptible Model Remains Resistant to Unrelated Pathogens Controlled by the NK Gene Complex
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Cutting Edge: Peyer’s Patch Plasmacytoid Dendritic Cells (pDCs) Produce Low Levels of Type I Interferons: Possible Role for IL-10, TGFβ, and Prostaglandin E2 in Conditioning a Unique Mucosal pDC Phenotype

Nikhat Contractor, Jennifer Louten, Leesun Kim, Christine A. Biron, Brian L. Kelsall
Journal: The Journal of Immunology
J Immunol (2007) 179 (5): 2690–2694.
https://doi.org/10.4049/jimmunol.179.5.2690
Published: 01 September 2007
View article titled, Cutting Edge: Peyer’s Patch Plasmacytoid Dendritic Cells (pDCs) Produce Low Levels of Type I Interferons: Possible Role for IL-10, TGFβ, and Prostaglandin E<sub>2</sub> in Conditioning a Unique Mucosal pDC Phenotype
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Journal Articles

Type 1 IFN Deficiency in the Absence of Normal Splenic Architecture during Lymphocytic Choriomeningitis Virus Infection

Jennifer Louten, Nico van Rooijen, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 3266–3272.
https://doi.org/10.4049/jimmunol.177.5.3266
Published: 01 September 2006
View article titled, Type 1 IFN Deficiency in the Absence of Normal Splenic Architecture during Lymphocytic Choriomeningitis Virus Infection
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Journal Articles

DAP12 Signaling Regulates Plasmacytoid Dendritic Cell Homeostasis and Down-Modulates Their Function during Viral Infection

Hanna Sjölin, Scott H. Robbins, Gilles Bessou, Åsa Hidmark, Elena Tomasello, Maria Johansson, Håkan Hall, Férose Charifi, Gunilla B. Karlsson Hedestam, Christine A. Biron, Klas Kärre, Petter Höglund, Eric Vivier, Marc Dalod
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 2908–2916.
https://doi.org/10.4049/jimmunol.177.5.2908
Published: 01 September 2006
View article titled, DAP12 Signaling Regulates Plasmacytoid Dendritic Cell Homeostasis and Down-Modulates Their Function during Viral Infection
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Journal Articles

MyD88-Dependent and -Independent Murine Cytomegalovirus Sensing for IFN-α Release and Initiation of Immune Responses In Vivo

Thomas Delale, André Paquin, Carine Asselin-Paturel, Marc Dalod, Géraldine Brizard, Elizabeth E. M. Bates, Philippe Kastner, Susan Chan, Shizuo Akira, Alain Vicari, Christine A. Biron, Giorgio Trinchieri, Francine Brière
Journal: The Journal of Immunology
J Immunol (2005) 175 (10): 6723–6732.
https://doi.org/10.4049/jimmunol.175.10.6723
Published: 15 November 2005
View article titled, MyD88-Dependent and -Independent Murine Cytomegalovirus Sensing for IFN-α Release and Initiation of Immune Responses In Vivo
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Journal Articles

Monocyte Chemoattractant Protein-1 and CCR2 Interactions Are Required for IFN-α/β-Induced Inflammatory Responses and Antiviral Defense in Liver

Kirsten L. Hokeness, William A. Kuziel, Christine A. Biron, Thais P. Salazar-Mather
Journal: The Journal of Immunology
J Immunol (2005) 174 (3): 1549–1556.
https://doi.org/10.4049/jimmunol.174.3.1549
Published: 01 February 2005
View article titled, Monocyte Chemoattractant Protein-1 and CCR2 Interactions Are Required for IFN-α/β-Induced Inflammatory Responses and Antiviral Defense in Liver
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Journal Articles

A Unique Mechanism for Innate Cytokine Promotion of T Cell Responses to Viral Infections

Gary C. Pien, Khuong B. Nguyen, Lene Malmgaard, Abhay R. Satoskar, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2002) 169 (10): 5827–5837.
https://doi.org/10.4049/jimmunol.169.10.5827
Published: 15 November 2002
View article titled, A Unique Mechanism for Innate Cytokine Promotion of T Cell Responses to Viral Infections
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Journal Articles

Coordinated and Distinct Roles for IFN-αβ, IL-12, and IL-15 Regulation of NK Cell Responses to Viral Infection

Khuong B. Nguyen, Thais P. Salazar-Mather, Marc Y. Dalod, Jeffrey B. Van Deusen, Xiao-qing Wei, Foo Y. Liew, Michael A. Caligiuri, Joan E. Durbin, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2002) 169 (8): 4279–4287.
https://doi.org/10.4049/jimmunol.169.8.4279
Published: 15 October 2002
View article titled, Coordinated and Distinct Roles for IFN-αβ, IL-12, and IL-15 Regulation of NK Cell Responses to Viral Infection
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Journal Articles

Cutting Edge: Inhibitory Functions of the Killer Cell Lectin-Like Receptor G1 Molecule During the Activation of Mouse NK Cells

Scott H. Robbins, Khuong B. Nguyen, Nobuaki Takahashi, Toshifumi Mikayama, Christine A. Biron, Laurent Brossay
Journal: The Journal of Immunology
J Immunol (2002) 168 (6): 2585–2589.
https://doi.org/10.4049/jimmunol.168.6.2585
Published: 15 March 2002
View article titled, Cutting Edge: Inhibitory Functions of the Killer Cell Lectin-Like Receptor G1 Molecule During the Activation of Mouse NK Cells
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Journal Articles

A Role for IFN-αβ in Virus Infection-Induced Sensitization to Endotoxin

Lesley A. Doughty, Khuong B. Nguyen, Joan E. Durbin, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2001) 166 (4): 2658–2664.
https://doi.org/10.4049/jimmunol.166.4.2658
Published: 15 February 2001
View article titled, A Role for IFN-αβ in Virus Infection-Induced Sensitization to Endotoxin
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Journal Articles

Cutting Edge: Selective IL-18 Requirements for Induction of Compartmental IFN-γ Responses During Viral Infection

Gary C. Pien, Abhay R. Satoskar, Kiyoshi Takeda, Shizuo Akira, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2000) 165 (9): 4787–4791.
https://doi.org/10.4049/jimmunol.165.9.4787
Published: 01 November 2000
View article titled, Cutting Edge: Selective IL-18 Requirements for Induction of Compartmental IFN-γ Responses During Viral Infection
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Journal Articles

Compartmental Differences in NK Cell Responsiveness to IL-12 During Lymphocytic Choriomeningitis Virus Infection

Gary C. Pien, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (2000) 164 (2): 994–1001.
https://doi.org/10.4049/jimmunol.164.2.994
Published: 15 January 2000
View article titled, Compartmental Differences in NK Cell Responsiveness to IL-12 During Lymphocytic Choriomeningitis Virus Infection
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Journal Articles

Synergism for Cytokine-Mediated Disease During Concurrent Endotoxin and Viral Challenges: Roles for NK and T Cell IFN-γ Production

Khuong B. Nguyen, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (1999) 162 (9): 5238–5246.
https://doi.org/10.4049/jimmunol.162.9.5238
Published: 01 May 1999
View article titled, Synergism for Cytokine-Mediated Disease During Concurrent Endotoxin and Viral Challenges: Roles for NK and T Cell IFN-γ Production
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Journal Articles

Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection

Melanie C. Ruzek, Bradley D. Pearce, Andrew H. Miller, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (1999) 162 (6): 3527–3533.
https://doi.org/10.4049/jimmunol.162.6.3527
Published: 15 March 1999
View article titled, Endogenous Glucocorticoids Protect Against Cytokine-Mediated Lethality During Viral Infection
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Journal Articles

CD4+ and CD8+ T Cell Interactions in IFN-γ and IL-4 Responses to Viral Infections: Requirements for IL-2

Helen C. Su, Leslie P. Cousens, Loren D. Fast, Mark K. Slifka, Richard D. Bungiro, Rafi Ahmed, Christine A. Biron
Journal: The Journal of Immunology
J Immunol (1998) 160 (10): 5007–5017.
https://doi.org/10.4049/jimmunol.160.10.5007
Published: 15 May 1998
View article titled, CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Interactions in IFN-γ and IL-4 Responses to Viral Infections: Requirements for IL-2
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