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Christopher D. Scharer
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Journal Articles

Persistent Antigen Harbored by Alveolar Macrophages Enhances the Maintenance of Lung-Resident Memory CD8+ T Cells

Jenna L. Lobby, Ida Uddbäck, Christopher D. Scharer, Tian Mi, Jeremy M. Boss, Allan R. Thomsen, Jan P. Christensen, Jacob E. Kohlmeier
Journal: The Journal of Immunology
J Immunol (2022) 209 (9): 1778–1787.
DOI: https://doi.org/10.4049/jimmunol.2200082
Published: 01 November 2022
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Defining the cis- and trans-regulatory architecture for human PD-1 in T Follicular Helper Cells

Michael Duane Powell, James R Rose, Dennis Neeld, Andrew R Rahmberg, Christopher D Scharer, Jeremy M Boss
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 112.21.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.112.21
Published: 01 May 2022
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Epigenome accessibility changes before and after activation reveal distinct and progressive differentiation for human memory T cell subsets

James R Rose, Andrew R Rahmberg, Michael D Powell, Christopher D Scharer, Jeremy M Boss
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 57.02.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.57.02
Published: 01 May 2022
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Somatic Diversification of Rearranged Antibody Gene Segments by Intra- and Interchromosomal Templated Mutagenesis

Gordon A. Dale, Daniel J. Wilkins, Jordan Rowley, Christopher D. Scharer, Christopher M. Tipton, Jennifer Hom, Jeremy M. Boss, Victor Corces, Ignacio Sanz, Joshy Jacob
Journal: The Journal of Immunology
J Immunol (2022) 208 (9): 2141–2153.
DOI: https://doi.org/10.4049/jimmunol.2100434
Published: 01 May 2022
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H3K27me3 Demethylase UTX Restrains Plasma Cell Formation

Anna K. Kania, Madeline J. Price, Lou-Ella George-Alexander, Dillon G. Patterson, Sakeenah L. Hicks, Christopher D. Scharer, Jeremy M. Boss
Journal: The Journal of Immunology
J Immunol (2022) 208 (8): 1873–1885.
DOI: https://doi.org/10.4049/jimmunol.2100948
Published: 15 April 2022
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An IRF4–MYC–mTORC1 Integrated Pathway Controls Cell Growth and the Proliferative Capacity of Activated B Cells during B Cell Differentiation In Vivo

Dillon G. Patterson, Anna K. Kania, Madeline J. Price, James R. Rose, Christopher D. Scharer, Jeremy M. Boss
Journal: The Journal of Immunology
J Immunol (2021) 207 (7): 1798–1811.
DOI: https://doi.org/10.4049/jimmunol.2100440
Published: 01 October 2021
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The Murine MHC Class II Super Enhancer IA/IE-SE Contains a Functionally Redundant CTCF-Binding Component and a Novel Element Critical for Maximal Expression

Parimal Majumder, Joshua T. Lee, Benjamin G. Barwick, Dillon G. Patterson, Alexander P. R. Bally, Christopher D. Scharer, Jeremy M. Boss
Journal: The Journal of Immunology
J Immunol (2021) 206 (9): 2221–2232.
DOI: https://doi.org/10.4049/jimmunol.2001089
Published: 01 May 2021
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Conserved Epigenetic Programming and Enhanced Heme Metabolism Drive Memory B Cell Reactivation

Madeline J. Price, Christopher D. Scharer, Anna K. Kania, Troy D. Randall, Jeremy M. Boss
Journal: The Journal of Immunology
J Immunol (2021) 206 (7): 1493–1504.
DOI: https://doi.org/10.4049/jimmunol.2000551
Published: 01 April 2021
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H3K27me3 demethylases are important epigenetic regulators of B cell differentiation

Anna Kania, Madeline Price, Christopher D. Scharer, Jeremy M Boss
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 155.9.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.155.9
Published: 01 May 2020
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Templated mutagenesis in B cell non-Ig genes

Karla Navarrete, Gordon A. Dale, Matthew C. Woodruff, Christopher D. Scharer, Jeremy M. Boss, Ignacio Sanz, Joshy Jacob
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 153.10.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.153.10
Published: 01 May 2020
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H3K9 dimethyltransferase G9a is an important epigenetic modulator of B cell differentiation

Lou-Ella George-Alexander, Anna Kania, Sakeenah Hicks, Tian Mi, Christopher D. Scharer, Jeremy Boss
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 151.14.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.151.14
Published: 01 May 2020
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IRF4 regulates the proliferative capacity of activated B cells during B cell differentiation

Dillon Patterson, Christopher D. Scharer, Tian Mi, Sakeenah L. Hicks, Qiang Zhang, Jeremy M Boss
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 151.26.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.151.26
Published: 01 May 2020
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Interferon gamma signaling regulates the generation of influenza-specific memory B cells

Chris A Risley, Sara L Stone, Christopher D. Scharer, Jeremy M Boss, Frances E Lund
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 171.8.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.171.8
Published: 01 May 2020
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Defining altered regulome structured in response to antigen co-receptors, toll-like receptors, and cytokine receptors stimuli to predispose early developing B cells for pathogenic fate in Systemic lupus erythematosus

Ankur Saini, Meixue Duan, Tian Mi, Sakeenah Hicks, Eun-Hyung Lee, Christopher D. Scharer, Jeremy M Boss, Greg Gibson, Ignacio Sanz
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 218.6.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.218.6
Published: 01 May 2020
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IgM, IgG, and IgA Influenza-Specific Plasma Cells Express Divergent Transcriptomes

Madeline J. Price, Sakeenah L. Hicks, John E. Bradley, Troy D. Randall, Jeremy M. Boss, Christopher D. Scharer
Journal: The Journal of Immunology
J Immunol (2019) 203 (8): 2121–2129.
DOI: https://doi.org/10.4049/jimmunol.1900285
Published: 15 October 2019
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LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development

Robert R. Haines, Christopher D. Scharer, Jenna L. Lobby, Jeremy M. Boss
Journal: The Journal of Immunology
J Immunol (2019) 203 (7): 1867–1881.
DOI: https://doi.org/10.4049/jimmunol.1900654
Published: 01 October 2019
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LSD1 epigenetically represses NF-κB target genes to regulate marginal zone B cell development

Robert Richard Haines, Christopher D. Scharer, Jeremy Boss
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 188.9.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.188.9
Published: 01 May 2019
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H3K27me3-specific demethylases modulate B cell development and differentiation

Anna Kania, Christopher D. Scharer, Madeline J Price, Robert Richard Haines, Lou-Ella Alexander-George, Jeremy Boss
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 188.15.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.188.15
Published: 01 May 2019
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Germinal center organization mediated by T-bet dependent expression of CXCR3 and CCR6

Jessica Nicole Peel, Sara L Stone, Christopher D. Scharer, Jeremy Boss, Frances E Lund
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 51.10.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.51.10
Published: 01 May 2019
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Epigenetic priming underpins enhanced memory B cell differentiation

Madeline J Price, Christopher D. Scharer, Anna K Kania, Tian Mi, Sakeenah L Hicks, Troy D Randall, Jeremy Boss
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 123.8.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.123.8
Published: 01 May 2019
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