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D J McKean
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Journal Articles

Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.

D. B. Graham, M. P. Bell, M. M. McCausland, C. J. Huntoon, J. van Deursen, W. A. Faubion, S. Crotty, D. J. McKean
Journal: The Journal of Immunology
J Immunol (2006) 176 (6): 3841.
https://doi.org/10.4049/jimmunol.176.6.3841-a
Published: 15 March 2006
View article titled, Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.
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Delta-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element.

K E Hedin, M P Bell, K R Kalli, C J Huntoon, B M Sharp, D J McKean
Journal: The Journal of Immunology
J Immunol (1997) 159 (11): 5431–5440.
https://doi.org/10.4049/jimmunol.159.11.5431
Published: 01 December 1997
View article titled, Delta-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element.
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Journal Articles

Aglycosylated and phosphatidylinositol-anchored MHC class I molecules are associated with calnexin. Evidence implicating the class I-connecting peptide segment in calnexin association.

B M Carreno, K L Schreiber, D J McKean, I Stroynowski, T H Hansen
Journal: The Journal of Immunology
J Immunol (1995) 154 (10): 5173–5180.
https://doi.org/10.4049/jimmunol.154.10.5173
Published: 15 May 1995
View article titled, Aglycosylated and phosphatidylinositol-anchored MHC class I molecules are associated with calnexin. Evidence implicating the class I-connecting peptide segment in calnexin association.
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Journal Articles

Murine T helper cell-2 lymphocytes express type I and type II IL-1 receptors, but only the type I receptor mediates costimulatory activity.

D J McKean, R P Podzorski, M P Bell, A E Nilson, C J Huntoon, J Slack, S K Dower, J Sims
Journal: The Journal of Immunology
J Immunol (1993) 151 (7): 3500–3510.
https://doi.org/10.4049/jimmunol.151.7.3500
Published: 01 October 1993
View article titled, Murine T helper cell-2 lymphocytes express type I and type II IL-1 receptors, but only the type I receptor mediates costimulatory activity.
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Journal Articles

Functional mapping of MHC class II polymorphic residues. The alpha-chain controls the specificity for binding an Ad-versus an A k-restricted peptide and the beta-chain region 65-67 controls T cell recognition but not peptide binding.

J M Lee, D J McKean, T H Watts
Journal: The Journal of Immunology
J Immunol (1991) 146 (9): 2952–2959.
https://doi.org/10.4049/jimmunol.146.9.2952
Published: 01 May 1991
View article titled, Functional mapping of MHC class II polymorphic residues. The alpha-chain controls the specificity for binding an Ad-versus an A k-restricted peptide and the beta-chain region 65-67 controls T cell recognition but not peptide binding.
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Journal Articles

Functional effects of N-linked oligosaccharides located on the external domain of murine class II molecules.

B Y Wei, J M Buerstedde, M Bell, C Chase, A Nilson, A Browne, L Pease, D J McKean
Journal: The Journal of Immunology
J Immunol (1991) 146 (7): 2358–2366.
https://doi.org/10.4049/jimmunol.146.7.2358
Published: 01 April 1991
View article titled, Functional effects of N-linked oligosaccharides located on the external domain of murine class II molecules.
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Journal Articles

The role of Ia in the formation of a T cell antigen-recognition complex.

T R Esch, D J McKean, D W Thomas
Journal: The Journal of Immunology
J Immunol (1990) 145 (12): 3979–3984.
https://doi.org/10.4049/jimmunol.145.12.3979
Published: 15 December 1990
View article titled, The role of Ia in the formation of a T cell antigen-recognition complex.
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Journal Articles

Regional and systemic distribution of anti-tumor x anti-CD3 heteroaggregate antibodies and cultured human peripheral blood lymphocytes in a human colon cancer xenograft.

H Nelson, P S Ramsey, L A Kerr, D J McKean, J H Donohue
Journal: The Journal of Immunology
J Immunol (1990) 145 (10): 3507–3515.
https://doi.org/10.4049/jimmunol.145.10.3507
Published: 15 November 1990
View article titled, Regional and systemic distribution of anti-tumor x anti-CD3 heteroaggregate antibodies and cultured human peripheral blood lymphocytes in a human colon cancer xenograft.
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Journal Articles

Heteroconjugate antibody-directed killing of autologous human renal carcinoma cells by in vitro-activated lymphocytes.

L Kerr, C Huntoon, J Donohue, P J Leibson, N H Bander, T Ghose, S J Luner, R Vessella, D J McKean
Journal: The Journal of Immunology
J Immunol (1990) 144 (10): 4060–4067.
https://doi.org/10.4049/jimmunol.144.10.4060
Published: 15 May 1990
View article titled, Heteroconjugate antibody-directed killing of autologous human renal carcinoma cells by in vitro-activated lymphocytes.
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Journal Articles

Regulatory effects of transforming growth factor-beta on IL-2- and IL-4-dependent T cell-cycle progression.

J J Ruegemer, S N Ho, J A Augustine, J W Schlager, M P Bell, D J McKean, R T Abraham
Journal: The Journal of Immunology
J Immunol (1990) 144 (5): 1767–1776.
https://doi.org/10.4049/jimmunol.144.5.1767
Published: 01 March 1990
View article titled, Regulatory effects of transforming growth factor-beta on IL-2- and IL-4-dependent T cell-cycle progression.
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Journal Articles

Human eosinophil-derived neurotoxin and eosinophil protein X are likely the same protein.

N R Slifman, P Venge, C G Peterson, D J McKean, G J Gleich
Journal: The Journal of Immunology
J Immunol (1989) 143 (7): 2317–2322.
https://doi.org/10.4049/jimmunol.143.7.2317
Published: 01 October 1989
View article titled, Human eosinophil-derived neurotoxin and eosinophil protein X are likely the same protein.
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Journal Articles

I-Ak polymorphisms define a functionally dominant region for the presentation of hen egg lysozyme peptides.

E F Rosloniec, L J Vitez, B N Beck, J M Buerstedde, D J McKean, D Landais, C Benoist, D Mathis, J H Freed
Journal: The Journal of Immunology
J Immunol (1989) 143 (1): 50–58.
https://doi.org/10.4049/jimmunol.143.1.50
Published: 01 July 1989
View article titled, I-Ak polymorphisms define a functionally dominant region for the presentation of hen egg lysozyme peptides.
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Journal Articles

Antigen presentation abrogated in cells expressing truncated Ia molecules.

N Nabavi, Z Ghogawala, A Myer, I J Griffith, W F Wade, Z Z Chen, D J McKean, L H Glimcher
Journal: The Journal of Immunology
J Immunol (1989) 142 (5): 1444–1447.
https://doi.org/10.4049/jimmunol.142.5.1444
Published: 01 March 1989
View article titled, Antigen presentation abrogated in cells expressing truncated Ia molecules.
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Journal Articles

Heteroconjugate antibodies enhance cell-mediated anti-herpes simplex virus immunity.

C V Paya, D J McKean, D M Segal, R A Schoon, S D Showalter, P J Leibson
Journal: The Journal of Immunology
J Immunol (1989) 142 (2): 666–671.
https://doi.org/10.4049/jimmunol.142.2.666
Published: 15 January 1989
View article titled, Heteroconjugate antibodies enhance cell-mediated anti-herpes simplex virus immunity.
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Journal Articles

IL-1 as a co-factor for lymphokine-secreting CD8+ murine T cells.

T Mizuochi, D J McKean, A Singer
Journal: The Journal of Immunology
J Immunol (1988) 141 (5): 1571–1575.
https://doi.org/10.4049/jimmunol.141.5.1571
Published: 01 September 1988
View article titled, IL-1 as a co-factor for lymphokine-secreting CD8+ murine T cells.
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Journal Articles

Interleukin 1-mediated activation of interleukin 4 (IL 4)-producing T lymphocytes. Proliferation by IL 4-dependent and IL 4-independent mechanisms.

S N Ho, R T Abraham, A Nilson, B S Handwerger, D J McKean
Journal: The Journal of Immunology
J Immunol (1987) 139 (5): 1532–1540.
https://doi.org/10.4049/jimmunol.139.5.1532
Published: 01 September 1987
View article titled, Interleukin 1-mediated activation of interleukin 4 (IL 4)-producing T lymphocytes. Proliferation by IL 4-dependent and IL 4-independent mechanisms.
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Journal Articles

Murine class II (Ia) molecules associate with human invariant chain.

L H Glimcher, B S Polla, A Poljak, C C Morton, D J McKean
Journal: The Journal of Immunology
J Immunol (1987) 138 (5): 1519–1523.
https://doi.org/10.4049/jimmunol.138.5.1519
Published: 01 March 1987
View article titled, Murine class II (Ia) molecules associate with human invariant chain.
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Journal Articles

Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein.

N R Slifman, D A Loegering, D J McKean, G J Gleich
Journal: The Journal of Immunology
J Immunol (1986) 137 (9): 2913–2917.
https://doi.org/10.4049/jimmunol.137.9.2913
Published: 01 November 1986
View article titled, Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein.
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Journal Articles

Characterization of cell lines expressing mutant I-Ab and I-Ak molecules allows the definition of distinct serologic epitopes on A alpha and A beta polypeptides.

B N Beck, J M Buerstedde, C J Krco, A E Nilson, C G Chase, D J McKean
Journal: The Journal of Immunology
J Immunol (1986) 136 (8): 2953–2961.
https://doi.org/10.4049/jimmunol.136.8.2953
Published: 15 April 1986
View article titled, Characterization of cell lines expressing mutant I-Ab and I-Ak molecules allows the definition of distinct serologic epitopes on A alpha and A beta polypeptides.
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Journal Articles

The role of IL 1 in the antigen-specific activation of murine class II-restricted T lymphocyte clones.

D J McKean, A Nilson, B N Beck, J Giri, S B Mizel, B S Handwerger
Journal: The Journal of Immunology
J Immunol (1985) 135 (5): 3205–3216.
https://doi.org/10.4049/jimmunol.135.5.3205
Published: 01 November 1985
View article titled, The role of IL 1 in the antigen-specific activation of murine class II-restricted T lymphocyte clones.
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