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Dale L. Greiner
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Journal Articles

Enhanced development of functional human innate immune cells in a novel mouse FLT3null NSG mouse strain expressing human FLT3L

Shantashri Vaidya, Pamela St. Louis, Lisa Burzenski, Dale L Greiner, Michael A Brehm, Leonard D Shultz
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 223.24.
https://doi.org/10.4049/jimmunol.204.Supp.223.24
Published: 01 May 2020
View article titled, Enhanced development of functional human innate immune cells in a novel mouse FLT3<sup>null</sup> NSG mouse strain expressing human FLT3L
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Journal Articles

Characterization and use of human insulin transgenic mouse models for type 1 diabetes

Nitin Purushottam Amdare, Leonard D Shultz, Dale L Greiner, Teresa P DiLorenzo
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 142.14.
https://doi.org/10.4049/jimmunol.204.Supp.142.14
Published: 01 May 2020
View article titled, Characterization and use of human insulin transgenic mouse models for type 1 diabetes
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Journal Articles

Development of a humanized mouse model for functional testing of biomaterial fibrosis

Dale L Greiner, Joshua C Doloff, Atieh Sadraei, Shady Farah, Michael A Brehm, Leonard D Shultz, Robert Langer, daniel G Anderson
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 126.37.
https://doi.org/10.4049/jimmunol.202.Supp.126.37
Published: 01 May 2019
View article titled, Development of a humanized mouse model for functional testing of biomaterial fibrosis
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Human Anti–HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1

Melissa A. Gawron, Mark Duval, Claudia Carbone, Smita Jaiswal, Aaron Wallace, Joseph C. Martin, III, Ann Dauphin, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, Jeremy Luban, Lisa A. Cavacini
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 799–804.
https://doi.org/10.4049/jimmunol.1801085
Published: 01 February 2019
View article titled, Human Anti–HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1
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Journal Articles

Transgenic expression of human IL15 in NOD-scid IL2rgnull (NSG) mice enhances the development and survival of functional human NK cells

Michael A. Brehm, Ken-Edwin Aryee, Lisa Bruzenksi, Dale L. Greiner, Leonard D. Shultz, James Keck
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 103.20.
https://doi.org/10.4049/jimmunol.200.Supp.103.20
Published: 01 May 2018
View article titled, Transgenic expression of human IL15 in NOD-<em>scid IL2rg</em><em><sup>null</sup></em> (NSG) mice enhances the development and survival of functional human NK cells
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NOD-scid IL2rgnull (NSG) mice deficient in murine MHC Class I and Class II expression support engraftment of functional human T cells in the absence of acute xenogeneic GVHD following injection of PBMC

Michael A. Brehm, Michael Wiles, Laurie Lea Kenney, Lisa Burzenski, James Keck, Dale L. Greiner, Leonard D. Shultz
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 57.13.
https://doi.org/10.4049/jimmunol.200.Supp.57.13
Published: 01 May 2018
View article titled, NOD-<em>scid IL2rg</em><em><sup>null</sup></em> (NSG) mice deficient in murine MHC Class I and Class II expression support engraftment of functional human T cells in the absence of acute xenogeneic GVHD following injection of PBMC
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Journal Articles

Development of a humanized mouse model that recapitulates the fibrotic response to biomaterial implants

Joshua C Doloff, Atieh Sadraei, Shady Farah, Rita Bortell, Michael A Brehm, Dale L Greiner, Daniel Anderson, Robert Langer
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 206.3.
https://doi.org/10.4049/jimmunol.198.Supp.206.3
Published: 01 May 2017
View article titled, Development of a humanized mouse model that recapitulates the fibrotic response to biomaterial implants
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Journal Articles

A novel anti-CD40 antibody prevents activation of alloreactive T cells and prolongs skin allograft survival

Sonal N Jangalwe, Kerry Ralph, Meera Ramanujam, Dale L Greiner, Michael A Brehm
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 140.32.
https://doi.org/10.4049/jimmunol.196.Supp.140.32
Published: 01 May 2016
View article titled, A novel anti-CD40 antibody prevents activation of alloreactive T cells and prolongs skin allograft survival
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Journal Articles

Human natural killer cell education is dynamically controlled by environmental and cell-intrinsic HLA

Jeanette Boudreau, Xiao-Rong Liu, Zeguo Zhao, Aaron Zhang, Leonard D Shultz, Dale L Greiner, Bo Dupont, Katharine C Hsu
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 202.6.
https://doi.org/10.4049/jimmunol.196.Supp.202.6
Published: 01 May 2016
View article titled, Human natural killer cell education is dynamically controlled by environmental and cell-intrinsic HLA
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The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice

Maximiliano Presa, Yi-Guang Chen, Alexandra E. Grier, Edward H. Leiter, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz, David V. Serreze
Journal: The Journal of Immunology
J Immunol (2015) 195 (7): 3011–3019.
https://doi.org/10.4049/jimmunol.1402446
Published: 01 October 2015
View article titled, The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-<em>scid</em> Mice
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Rapid Recruitment and Activation of Macrophages by Anti-Gal/α-Gal Liposome Interaction Accelerates Wound Healing

Kim M. Wigglesworth, Waldemar J. Racki, Rabinarayan Mishra, Eva Szomolanyi-Tsuda, Dale L. Greiner, Uri Galili
Journal: The Journal of Immunology
J Immunol (2011) 186 (7): 4422–4432.
https://doi.org/10.4049/jimmunol.1002324
Published: 01 April 2011
View article titled, Rapid Recruitment and Activation of Macrophages by Anti-Gal/α-Gal Liposome Interaction Accelerates Wound Healing
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Journal Articles

TLR Agonists Prevent the Establishment of Allogeneic Hematopoietic Chimerism in Mice Treated with Costimulation Blockade

David M. Miller, Thomas B. Thornley, Todd Pearson, Annie J. Kruger, Masahiro Yamazaki, Leonard D. Shultz, Raymond M. Welsh, Michael A. Brehm, Aldo A. Rossini, Dale L. Greiner
Journal: The Journal of Immunology
J Immunol (2009) 182 (9): 5547–5559.
https://doi.org/10.4049/jimmunol.0802077
Published: 01 May 2009
View article titled, TLR Agonists Prevent the Establishment of Allogeneic Hematopoietic Chimerism in Mice Treated with Costimulation Blockade
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Journal Articles

Type 1 IFN Mediates Cross-Talk between Innate and Adaptive Immunity That Abrogates Transplantation Tolerance

Thomas B. Thornley, Nancy E. Phillips, Britte C. Beaudette-Zlatanova, Thomas G. Markees, Kapil Bahl, Michael A. Brehm, Leonard D. Shultz, Evelyn A. Kurt-Jones, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini, Dale L. Greiner
Journal: The Journal of Immunology
J Immunol (2007) 179 (10): 6620–6629.
https://doi.org/10.4049/jimmunol.179.10.6620
Published: 15 November 2007
View article titled, Type 1 IFN Mediates Cross-Talk between Innate and Adaptive Immunity That Abrogates Transplantation Tolerance
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A Novel Alloantigen-Specific CD8+PD1+ Regulatory T Cell Induced by ICOS-B7h Blockade In Vivo

Atsushi Izawa, Kazuhiro Yamaura, Monica J. Albin, Mollie Jurewicz, Katsunori Tanaka, Michael R. Clarkson, Takuya Ueno, Antje Habicht, Gordon J. Freeman, Hideo Yagita, Reza Abdi, Todd Pearson, Dale L. Greiner, Mohamed H. Sayegh, Nader Najafian
Journal: The Journal of Immunology
J Immunol (2007) 179 (2): 786–796.
https://doi.org/10.4049/jimmunol.179.2.786
Published: 15 July 2007
View article titled, A Novel Alloantigen-Specific CD8<sup>+</sup>PD1<sup>+</sup> Regulatory T Cell Induced by ICOS-B7h Blockade In Vivo
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Journal Articles

TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat

Danny Zipris, Egil Lien, Anjali Nair, Jenny X. Xie, Dale L. Greiner, John P. Mordes, Aldo A. Rossini
Journal: The Journal of Immunology
J Immunol (2007) 178 (2): 693–701.
https://doi.org/10.4049/jimmunol.178.2.693
Published: 15 January 2007
View article titled, TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat
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Journal Articles

A Regulatory CD4+ T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD25 Nor Foxp3

Jan-Luuk Hillebrands, Barbara Whalen, Jeroen T. J. Visser, Jasper Koning, Kenneth D. Bishop, Jean Leif, Jan Rozing, John P. Mordes, Dale L. Greiner, Aldo A. Rossini
Journal: The Journal of Immunology
J Immunol (2006) 177 (11): 7820–7832.
https://doi.org/10.4049/jimmunol.177.11.7820
Published: 01 December 2006
View article titled, A Regulatory CD4<sup>+</sup> T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD25 Nor Foxp3
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Partial versus Full Allogeneic Hemopoietic Chimerization Is a Preferential Means to Inhibit Type 1 Diabetes as the Latter Induces Generalized Immunosuppression

David V. Serreze, Melissa A. Osborne, Yi-Guang Chen, Harold D. Chapman, Todd Pearson, Michael A. Brehm, Dale L. Greiner
Journal: The Journal of Immunology
J Immunol (2006) 177 (10): 6675–6684.
https://doi.org/10.4049/jimmunol.177.10.6675
Published: 15 November 2006
View article titled, Partial versus Full Allogeneic Hemopoietic Chimerization Is a Preferential Means to Inhibit Type 1 Diabetes as the Latter Induces Generalized Immunosuppression
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Journal Articles

TLR Agonists Abrogate Costimulation Blockade-Induced Prolongation of Skin Allografts

Thomas B. Thornley, Michael A. Brehm, Thomas G. Markees, Leonard D. Shultz, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini, Dale L. Greiner
Journal: The Journal of Immunology
J Immunol (2006) 176 (3): 1561–1570.
https://doi.org/10.4049/jimmunol.176.3.1561
Published: 01 February 2006
View article titled, TLR Agonists Abrogate Costimulation Blockade-Induced Prolongation of Skin Allografts
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Journal Articles

Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2Rγnull Mice Engrafted with Mobilized Human Hemopoietic Stem Cells

Leonard D. Shultz, Bonnie L. Lyons, Lisa M. Burzenski, Bruce Gott, Xiaohua Chen, Stanley Chaleff, Malak Kotb, Stephen D. Gillies, Marie King, Julie Mangada, Dale L. Greiner, Rupert Handgretinger
Journal: The Journal of Immunology
J Immunol (2005) 174 (10): 6477–6489.
https://doi.org/10.4049/jimmunol.174.10.6477
Published: 15 May 2005
View article titled, Human Lymphoid and Myeloid Cell Development in NOD/LtSz-<em>scid IL2R</em>γ<sup><em>null</em></sup> Mice Engrafted with Mobilized Human Hemopoietic Stem Cells
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Journal Articles

TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats

Danny Zipris, Egil Lien, Jenny X. Xie, Dale L. Greiner, John P. Mordes, Aldo A. Rossini
Journal: The Journal of Immunology
J Immunol (2005) 174 (1): 131–142.
https://doi.org/10.4049/jimmunol.174.1.131
Published: 01 January 2005
View article titled, TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats
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