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Dario A. A. Vignali
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Journal Articles

Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3

Pragati Agnihotri, Arjun K. Mishra, Priyanka Agarwal, Kate M. Vignali, Creg J. Workman, Dario A. A. Vignali, Roy A. Mariuzza
Journal: The Journal of Immunology
J Immunol (2022) 209 (8): 1586–1594.
DOI: https://doi.org/10.4049/jimmunol.2200309
Published: 15 October 2022
View article titled, Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3
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Includes: Supplementary data
Journal Articles

Interferon Gamma Induction of TH1-like Tregs Controls Anti-viral Responses

Angela Marie Gocher, Jian Cui, Andrea Szymczak-Workman, Kate Vignali, Julianna N Latini, Gwen P Pieklo, Lyndsay Avery, Ellyse L Cipolla, Brydie R Huckestein, Lee Hedden, Marlies Meisel, John F Alcorn, Lawrence P Kane, Creg J. Workman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 53.23.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.53.23
Published: 01 May 2022
View article titled, Interferon Gamma Induction of T<sub>H</sub>1-like T<sub>regs</sub> Controls Anti-viral Responses
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Journal Articles

Interferon gamma production by regulatory T cells is required for response to cancer immunotherapy

Angela Marie Gocher, Sanah Handu, Creg J Workman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 244.8.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.244.8
Published: 01 May 2020
View article titled, Interferon gamma production by regulatory T cells is required for response to cancer immunotherapy
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Journal Articles

B7-H4 Modulates Regulatory CD4+ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex

Joseph R. Podojil, Ming-Yi Chiang, Igal Ifergan, Ronald Copeland, Linda N. Liu, Sebastien Maloveste, Solomon Langermann, David Liebenson, Roumen Balabanov, Hongbo Chi, Lieping Chen, Dario A. A. Vignali, Stephen D. Miller
Journal: The Journal of Immunology
J Immunol (2018) 201 (3): 897–907.
DOI: https://doi.org/10.4049/jimmunol.1700811
Published: 01 August 2018
View article titled, B7-H4 Modulates Regulatory CD4<sup>+</sup> T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex
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Includes: Supplementary data
Journal Articles

Treg-specific LAG3 deletion reveals a key role for LAG3 in regulatory T cells to inhibit CNS autoimmunity

Youg Raj Thaker, Lawrence P. Andrews, Creg J. Workman, Dario A. A. Vignali, Arlene H. Sharpe
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 101.7.
DOI: https://doi.org/10.4049/jimmunol.200.Supp.101.7
Published: 01 May 2018
View article titled, Treg-specific LAG3 deletion reveals a key role for LAG3 in regulatory T cells to inhibit CNS autoimmunity
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Journal Articles

Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development

Matthew L. Bettini, Po-Chein Chou, Clifford S. Guy, Thomas Lee, Kate M. Vignali, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2017) 199 (5): 1555–1560.
DOI: https://doi.org/10.4049/jimmunol.1700069
Published: 01 September 2017
View article titled, Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development
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Includes: Supplementary data
Journal Articles

Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?

In Special Collection:
Brief Reviews
Anabelle Visperas, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2016) 197 (10): 3762–3770.
DOI: https://doi.org/10.4049/jimmunol.1601118
Published: 15 November 2016
View article titled, Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?
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Journal Articles

TCR Affinity and Tolerance Mechanisms Converge To Shape T Cell Diabetogenic Potential

Maria Bettini, Lori Blanchfield, Ashley Castellaw, Qianxia Zhang, Maki Nakayama, Matthew P. Smeltzer, Hui Zhang, Kristin A. Hogquist, Brian D. Evavold, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2014) 193 (2): 571–579.
DOI: https://doi.org/10.4049/jimmunol.1400043
Published: 15 July 2014
View article titled, TCR Affinity and Tolerance Mechanisms Converge To Shape T Cell Diabetogenic Potential
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Includes: Supplementary data
Journal Articles

Membrane Association of the CD3ε Signaling Domain Is Required for Optimal T Cell Development and Function

Matthew L. Bettini, Clifford Guy, Pradyot Dash, Kate M. Vignali, David E. Hamm, Jessica Dobbins, Etienne Gagnon, Paul G. Thomas, Kai W. Wucherpfennig, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2014) 193 (1): 258–267.
DOI: https://doi.org/10.4049/jimmunol.1400322
Published: 01 July 2014
View article titled, Membrane Association of the CD3ε Signaling Domain Is Required for Optimal T Cell Development and Function
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Includes: Supplementary data
Journal Articles

Regulatory T Cells Limit Induction of Protective Immunity and Promote Immune Pathology following Intestinal Helminth Infection

Deepali V. Sawant, David M. Gravano, Peter Vogel, Paul Giacomin, David Artis, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2014) 192 (6): 2904–2912.
DOI: https://doi.org/10.4049/jimmunol.1202502
Published: 15 March 2014
View article titled, Regulatory T Cells Limit Induction of Protective Immunity and Promote Immune Pathology following Intestinal Helminth Infection
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Includes: Supplementary data
Journal Articles

Retraction: Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance

Vandana Chaturvedi, Lauren W. Collison, Clifford S. Guy, Creg J. Workman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2013) 191 (4): 2018.
DOI: https://doi.org/10.4049/jimmunol.1390040
Published: 15 August 2013
View article titled, Retraction: Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance
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Journal Articles

Human Prostate Tumor Antigen–Specific CD8+ Regulatory T Cells Are Inhibited by CTLA-4 or IL-35 Blockade

Brian M. Olson, Ewa Jankowska-Gan, Jordan T. Becker, Dario A. A. Vignali, William J. Burlingham, Douglas G. McNeel
Journal: The Journal of Immunology
J Immunol (2012) 189 (12): 5590–5601.
DOI: https://doi.org/10.4049/jimmunol.1201744
Published: 15 December 2012
View article titled, Human Prostate Tumor Antigen–Specific CD8<sup>+</sup> Regulatory T Cells Are Inhibited by CTLA-4 or IL-35 Blockade
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Includes: Supplementary data
Journal Articles

Response to Comment on “Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways”

Andrea L. Szymczak-Workman, Greg M. Delgoffe, Douglas R. Green, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5204–5205.
DOI: https://doi.org/10.4049/jimmunol.1290024
Published: 01 June 2012
View article titled, Response to Comment on “Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways”
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Journal Articles

The Plasticity of Regulatory T Cell Function

Meenu R. Pillai, Lauren W. Collison, Xiaohua Wang, David Finkelstein, Jerold E. Rehg, Kelli Boyd, Andrea L. Szymczak-Workman, Teresa Doggett, Thomas S. Griffith, Thomas A. Ferguson, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2011) 187 (10): 4987–4997.
DOI: https://doi.org/10.4049/jimmunol.1102173
Published: 15 November 2011
View article titled, The Plasticity of Regulatory T Cell Function
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Includes: Supplementary data
Journal Articles

Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways

Andrea L. Szymczak-Workman, Greg M. Delgoffe, Douglas R. Green, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2011) 187 (9): 4416–4420.
DOI: https://doi.org/10.4049/jimmunol.1100548
Published: 01 November 2011
View article titled, Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways
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Journal Articles

Cutting Edge: Accelerated Autoimmune Diabetes in the Absence of LAG-3

Maria Bettini, Andrea L. Szymczak-Workman, Karen Forbes, Ashley H. Castellaw, Mark Selby, Xiaoyu Pan, Charles G. Drake, Alan J. Korman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2011) 187 (7): 3493–3498.
DOI: https://doi.org/10.4049/jimmunol.1100714
Published: 01 October 2011
View article titled, Cutting Edge: Accelerated Autoimmune Diabetes in the Absence of LAG-3
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Includes: Supplementary data
Journal Articles

Cutting Edge: Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance

Vandana Chaturvedi, Lauren W. Collison, Clifford S. Guy, Creg J. Workman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2011) 186 (12): 6661–6666.
DOI: https://doi.org/10.4049/jimmunol.1100315
Published: 15 June 2011
View article titled, Cutting Edge: Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance
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Includes: Supplementary data
Journal Articles

CD4 on the Road to Coreceptor Status

In Special Collection:
Pillars of Immunology
Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2010) 184 (11): 5933–5934.
DOI: https://doi.org/10.4049/jimmunol.1090037
Published: 01 June 2010
View article titled, CD4 on the Road to Coreceptor Status
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Journal Articles

Central Nervous System Destruction Mediated by Glutamic Acid Decarboxylase-Specific CD4+ T Cells

Amanda R. Burton, Zachary Baquet, George S. Eisenbarth, Roland Tisch, Richard Smeyne, Creg J. Workman, Dario A. A. Vignali
Journal: The Journal of Immunology
J Immunol (2010) 184 (9): 4863–4870.
DOI: https://doi.org/10.4049/jimmunol.0903728
Published: 01 May 2010
View article titled, Central Nervous System Destruction Mediated by Glutamic Acid Decarboxylase-Specific CD4<sup>+</sup> T Cells
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Includes: Supplementary data
Journal Articles

Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells

Joseph F. Grosso, Monica V. Goldberg, Derese Getnet, Tullia C. Bruno, Hung-Rong Yen, Kristin J. Pyle, Edward Hipkiss, Dario A. A. Vignali, Drew M. Pardoll, Charles G. Drake
Journal: The Journal of Immunology
J Immunol (2009) 182 (11): 6659–6669.
DOI: https://doi.org/10.4049/jimmunol.0804211
Published: 01 June 2009
View article titled, Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells
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