1-13 of 13
David A. Fruman
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

A Case for Phosphoinositide 3-Kinase–Targeted Therapy for Infectious Disease

In Special Collection:
Brief Reviews
Folayemi Adefemi, David A. Fruman, Aaron J. Marshall
Journal: The Journal of Immunology
J Immunol (2020) 205 (12): 3237–3245.
https://doi.org/10.4049/jimmunol.2000599
Published: 15 December 2020
View article titled, A Case for Phosphoinositide 3-Kinase–Targeted Therapy for Infectious Disease
Open the PDF for A Case for Phosphoinositide 3-Kinase–Targeted Therapy for Infectious Disease in another window
Add to Citation Manager
Journal Articles

Fasting Mimicking Diet promotes immunotherapy-associated changes and inhibits autophagy to promote cancer free survival in Acute Lymphoblastic Leukemia models

Roberta Buono, Jonathan Tucci, Raffaello Cutri, Novella Guidi, Serghei Mangul, Matteo Pellegrini, David A Fruman, Steven D. Mittelman, Valter Longo
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 240.10.
https://doi.org/10.4049/jimmunol.204.Supp.240.10
Published: 01 May 2020
View article titled, Fasting Mimicking Diet promotes immunotherapy-associated changes and inhibits autophagy to promote cancer free survival in Acute Lymphoblastic Leukemia models
Add to Citation Manager
Journal Articles

The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes

Honyin Chiu, Leandra V. Jackson, Kwon Ik Oh, Annie Mai, Ze’ev A. Ronai, Davide Ruggero, David A. Fruman
Journal: The Journal of Immunology
J Immunol (2019) 202 (2): 579–590.
https://doi.org/10.4049/jimmunol.1800602
Published: 15 January 2019
View article titled, The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes
Open the PDF for The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Context-Specific Function of S6K2 in Th Cell Differentiation

Christine Pai, Craig M. Walsh, David A. Fruman
Journal: The Journal of Immunology
J Immunol (2016) 197 (8): 3049–3058.
https://doi.org/10.4049/jimmunol.1600167
Published: 15 October 2016
View article titled, Context-Specific Function of S6K2 in Th Cell Differentiation
Open the PDF for Context-Specific Function of S6K2 in Th Cell Differentiation in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

A Novel Role for the 4E-BP/eIF4E Axis in B Cell Antibody Class Switching

Honyin Chiu, Lomon So, David A Fruman
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 56.4.
https://doi.org/10.4049/jimmunol.196.Supp.56.4
Published: 01 May 2016
View article titled, A Novel Role for the 4E-BP/eIF4E Axis in B Cell Antibody Class Switching
Add to Citation Manager
Journal Articles

FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase

Stéphanie Fabre, Florent Carrette, Jing Chen, Valérie Lang, Monique Semichon, Christine Denoyelle, Vladimir Lazar, Nicolas Cagnard, Anne Dubart-Kupperschmitt, Marianne Mangeney, David A. Fruman, Georges Bismuth
Journal: The Journal of Immunology
J Immunol (2008) 181 (5): 2980–2989.
https://doi.org/10.4049/jimmunol.181.5.2980
Published: 01 September 2008
View article titled, FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase
Open the PDF for FOXO1 Regulates L-Selectin and a Network of Human T Cell Homing Molecules Downstream of Phosphatidylinositol 3-Kinase in another window
Add to Citation Manager
Journal Articles

T Cell Ig and Mucin Domain-1-Mediated T Cell Activation Requires Recruitment and Activation of Phosphoinositide 3-Kinase

Anjali J. de Souza, Jean S. Oak, Ryan Jordanhazy, Rosemarie H. DeKruyff, David A. Fruman, Lawrence P. Kane
Journal: The Journal of Immunology
J Immunol (2008) 180 (10): 6518–6526.
https://doi.org/10.4049/jimmunol.180.10.6518
Published: 15 May 2008
View article titled, T Cell Ig and Mucin Domain-1-Mediated T Cell Activation Requires Recruitment and Activation of Phosphoinositide 3-Kinase
Open the PDF for T Cell Ig and Mucin Domain-1-Mediated T Cell Activation Requires Recruitment and Activation of Phosphoinositide 3-Kinase in another window
Add to Citation Manager
Journal Articles

Class IA Phosphoinositide 3-Kinase Modulates Basal Lymphocyte Motility in the Lymph Node

Melanie P. Matheu, Jonathan A. Deane, Ian Parker, David A. Fruman, Michael D. Cahalan
Journal: The Journal of Immunology
J Immunol (2007) 179 (4): 2261–2269.
https://doi.org/10.4049/jimmunol.179.4.2261
Published: 15 August 2007
View article titled, Class IA Phosphoinositide 3-Kinase Modulates Basal Lymphocyte Motility in the Lymph Node
Open the PDF for Class IA Phosphoinositide 3-Kinase Modulates Basal Lymphocyte Motility in the Lymph Node in another window
Add to Citation Manager
Includes: Multimedia, Supplementary data
Journal Articles

FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes

Jing Chen, Isharat Yusuf, Hilde-Marie Andersen, David A. Fruman
Journal: The Journal of Immunology
J Immunol (2006) 176 (5): 2711–2721.
https://doi.org/10.4049/jimmunol.176.5.2711
Published: 01 March 2006
View article titled, FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes
Open the PDF for FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes in another window
Add to Citation Manager
Journal Articles

Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands

Xiaocui Zhu, Rebecca Hart, Mi Sook Chang, Jong-Woo Kim, Sun Young Lee, Yun Anna Cao, Dennis Mock, Eugene Ke, Brian Saunders, Angela Alexander, Joella Grossoehme, Keng-Mean Lin, Zhen Yan, Robert Hsueh, Jamie Lee, Richard H. Scheuermann, David A. Fruman, William Seaman, Shankar Subramaniam, Paul Sternweis, Melvin I. Simon, Sangdun Choi
Journal: The Journal of Immunology
J Immunol (2004) 173 (12): 7141–7149.
https://doi.org/10.4049/jimmunol.173.12.7141
Published: 15 December 2004
View article titled, Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands
Open the PDF for Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Enhanced T Cell Proliferation in Mice Lacking the p85β Subunit of Phosphoinositide 3-Kinase

Jonathan A. Deane, Matthew J. Trifilo, Claudine M. Yballe, Sangdun Choi, Thomas E. Lane, David A. Fruman
Journal: The Journal of Immunology
J Immunol (2004) 172 (11): 6615–6625.
https://doi.org/10.4049/jimmunol.172.11.6615
Published: 01 June 2004
View article titled, Enhanced T Cell Proliferation in Mice Lacking the p85β Subunit of Phosphoinositide 3-Kinase
Open the PDF for Enhanced T Cell Proliferation in Mice Lacking the p85β Subunit of Phosphoinositide 3-Kinase in another window
Add to Citation Manager
Journal Articles

Proliferation and Survival of Activated B Cells Requires Sustained Antigen Receptor Engagement and Phosphoinositide 3-Kinase Activation

Amber C. Donahue, David A. Fruman
Journal: The Journal of Immunology
J Immunol (2003) 170 (12): 5851–5860.
https://doi.org/10.4049/jimmunol.170.12.5851
Published: 15 June 2003
View article titled, Proliferation and Survival of Activated B Cells Requires Sustained Antigen Receptor Engagement and Phosphoinositide 3-Kinase Activation
Open the PDF for Proliferation and Survival of Activated B Cells Requires Sustained Antigen Receptor Engagement and Phosphoinositide 3-Kinase Activation in another window
Add to Citation Manager
Journal Articles

Phosphatidylinositol 3-Kinase Confers Resistance to Encephalomyocarditis and Herpes Simplex Virus-Induced Cell Death Through the Activation of Distinct Downstream Effectors

Christine Prejean, Tulika Sarma, Oleg Kurnasov, Anna Usacheva, Brian Hemmings, Lewis Cantley, David A. Fruman, Lynda A. Morrison, R. Mark Buller, Oscar R. Colamonici
Journal: The Journal of Immunology
J Immunol (2001) 167 (8): 4553–4559.
https://doi.org/10.4049/jimmunol.167.8.4553
Published: 15 October 2001
View article titled, Phosphatidylinositol 3-Kinase Confers Resistance to Encephalomyocarditis and Herpes Simplex Virus-Induced Cell Death Through the Activation of Distinct Downstream Effectors
Open the PDF for Phosphatidylinositol 3-Kinase Confers Resistance to Encephalomyocarditis and Herpes Simplex Virus-Induced Cell Death Through the Activation of Distinct Downstream Effectors in another window
Add to Citation Manager