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David A. Price
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Journal Articles

Identity of virus-specific and cross-reactive T cell memory to mpox

Sarah Adamo, Yu Gao, Curtis Cai, Thomas R Müller, Julia Niessl, Mily Akhirunnesa, Hans-Gustaf Ljunggren, Matti Sällberg, Peter Bergman, Anna-Mia Ekström, Alba Grifoni, Alessandro Sette, David A. Price, Marcus Buggert
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 59.47.
https://doi.org/10.4049/jimmunol.210.Supp.59.47
Published: 01 May 2023
View article titled, Identity of virus-specific and cross-reactive T cell memory to mpox
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Journal Articles

Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8+ T Cells in Elderly Humans

Francesco Nicoli, Mariela P. Cabral-Piccin, Laura Papagno, Eleonora Gallerani, Mathieu Fusaro, Victor Folcher, Marion Dubois, Emmanuel Clave, Hélène Vallet, Justin J. Frere, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Antoine Toubert, Loïc Dupré, Jacques Boddaert, Antonella Caputo, Riccardo Gavioli, Victor Appay
Journal: The Journal of Immunology
J Immunol (2022) 208 (3): 562–570.
https://doi.org/10.4049/jimmunol.2100194
Published: 01 February 2022
View article titled, Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8<sup>+</sup> T Cells in Elderly Humans
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Includes: Supplementary data
Journal Articles

Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells

Stephen Man, James E. Redman, Deborah L. Cross, David K. Cole, Ilona Can, Bethan Davies, Shaikh Shimaz Hashimdeen, Reiss Reid, Sian Llewellyn-Lacey, Kelly L. Miners, Kristin Ladell, Anya Lissina, Paul E. Brown, Linda Wooldridge, David A. Price, Pierre J. Rizkallah
Journal: The Journal of Immunology
J Immunol (2021) 207 (4): 1009–1017.
https://doi.org/10.4049/jimmunol.2000756
Published: 15 August 2021
View article titled, Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells
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Includes: Supplementary data
Journal Articles

T cell receptor repertoire features display universal rules for selection and plasticity in the functional CD4 T cell subsets

Sofya A Kasatskaya, Kristin Ladell, Evgeny S. Egorov, David A. Price, Dmitriy Chudakov
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 230.9.
https://doi.org/10.4049/jimmunol.204.Supp.230.9
Published: 01 May 2020
View article titled, T cell receptor repertoire features display universal rules for selection and plasticity in the functional CD4 T cell subsets
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Journal Articles

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

Corinne J. Smith, Vanessa Venturi, Maire F. Quigley, Holly Turula, Emma Gostick, Kristin Ladell, Brenna J. Hill, Danielle Himelfarb, Kylie M. Quinn, Hui Yee Greenaway, Thurston H. Y. Dang, Robert A. Seder, Daniel C. Douek, Ann B. Hill, Miles P. Davenport, David A. Price, Christopher M. Snyder
Journal: The Journal of Immunology
J Immunol (2020) 204 (1): 112–121.
https://doi.org/10.4049/jimmunol.1900455
Published: 01 January 2020
View article titled, Stochastic Expansions Maintain the Clonal Stability of CD8<sup>+</sup> T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus
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Includes: Supplementary data
Journal Articles

CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential

Gabriele De Simone, Emilia M. C. Mazza, Antonino Cassotta, Alexey N. Davydov, Mirela Kuka, Veronica Zanon, Federica De Paoli, Eloise Scamardella, Maria Metsger, Alessandra Roberto, Karolina Pilipow, Federico S. Colombo, Elena Tenedini, Enrico Tagliafico, Luca Gattinoni, Domenico Mavilio, Clelia Peano, David A. Price, Satya P. Singh, Joshua M. Farber, Valentina Serra, Francesco Cucca, Francesco Ferrari, Valeria Orrù, Edoardo Fiorillo, Matteo Iannacone, Dmitriy M. Chudakov, Federica Sallusto, Enrico Lugli
Journal: The Journal of Immunology
J Immunol (2019) 203 (12): 3179–3189.
https://doi.org/10.4049/jimmunol.1901072
Published: 15 December 2019
View article titled, CXCR3 Identifies Human Naive CD8<sup>+</sup> T Cells with Enhanced Effector Differentiation Potential
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Includes: Supplementary data
Journal Articles

Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells

Benjamin J. Meckiff, Kristin Ladell, James E. McLaren, Gordon B. Ryan, Alison M. Leese, Eddie A. James, David A. Price, Heather M. Long
Journal: The Journal of Immunology
J Immunol (2019) 203 (5): 1276–1287.
https://doi.org/10.4049/jimmunol.1900377
Published: 01 September 2019
View article titled, Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4<sup>+</sup> T Cells
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Includes: Supplementary data
Journal Articles

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

James E. McLaren, Mathew Clement, Morgan Marsden, Kelly L. Miners, Sian Llewellyn-Lacey, Emma J. Grant, Anzelika Rubina, Silvia Gimeno Brias, Emma Gostick, Maria A. Stacey, Selinda J. Orr, Richard J. Stanton, Kristin Ladell, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 943–955.
https://doi.org/10.4049/jimmunol.1701757
Published: 01 February 2019
View article titled, IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
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Includes: Supplementary data
Journal Articles

CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin

Michelle L. McCully, Kristin Ladell, Robert Andrews, Rhiannon E. Jones, Kelly L. Miners, Laureline Roger, Duncan M. Baird, Mark J. Cameron, Zita M. Jessop, Iain S. Whitaker, Eleri L. Davies, David A. Price, Bernhard Moser
Journal: The Journal of Immunology
J Immunol (2018) 200 (5): 1639–1650.
https://doi.org/10.4049/jimmunol.1701377
Published: 01 March 2018
View article titled, CCR8 Expression Defines Tissue-Resident Memory T Cells in Human Skin
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Includes: Supplementary data
Journal Articles

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses

Alice Gutjahr, Laura Papagno, Francesco Nicoli, Alain Lamoureux, Fabienne Vernejoul, Thierry Lioux, Emma Gostick, David A. Price, Gérard Tiraby, Eric Perouzel, Victor Appay, Bernard Verrier, Stéphane Paul
Journal: The Journal of Immunology
J Immunol (2017) 198 (11): 4205–4209.
https://doi.org/10.4049/jimmunol.1602131
Published: 01 June 2017
View article titled, Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses
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Includes: Supplementary data
Journal Articles

HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection

Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, Paul A. Goepfert
Journal: The Journal of Immunology
J Immunol (2016) 196 (8): 3276–3286.
https://doi.org/10.4049/jimmunol.1502411
Published: 15 April 2016
View article titled, HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
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Includes: Supplementary data
Journal Articles

Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand

Anna Lissina, Olivia Briceño, Georgia Afonso, Martin Larsen, Emma Gostick, David A. Price, Roberto Mallone, Victor Appay
Journal: The Journal of Immunology
J Immunol (2016) 196 (1): 256–263.
https://doi.org/10.4049/jimmunol.1501140
Published: 01 January 2016
View article titled, Priming of Qualitatively Superior Human Effector CD8<sup>+</sup> T Cells Using TLR8 Ligand Combined with FLT3 Ligand
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Includes: Supplementary data
Journal Articles

Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers

Christopher J. Holland, Garry Dolton, Martin Scurr, Kristin Ladell, Andrea J. Schauenburg, Kelly Miners, Florian Madura, Andrew K. Sewell, David A. Price, David K. Cole, Andrew J. Godkin
Journal: The Journal of Immunology
J Immunol (2015) 195 (12): 5827–5836.
https://doi.org/10.4049/jimmunol.1402787
Published: 15 December 2015
View article titled, Enhanced Detection of Antigen-Specific CD4<sup>+</sup> T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers
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Includes: Supplementary data
Journal Articles

Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease

Kristin Ladell, Mette D. Hazenberg, Mark Fitch, Claire Emson, Bridget K. McEvoy-Hein Asgarian, Jeff E. Mold, Corey Miller, Robert Busch, David A. Price, Marc K. Hellerstein, Joseph M. McCune
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4096–4105.
https://doi.org/10.4049/jimmunol.1500799
Published: 01 November 2015
View article titled, Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease
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Includes: Supplementary data
Journal Articles

Determinants of Gliadin-Specific T Cell Selection in Celiac Disease

Jan Petersen, Jeroen van Bergen, Khai Lee Loh, Yvonne Kooy-Winkelaar, Dennis X. Beringer, Allan Thompson, Sjoerd F. Bakker, Chris J. J. Mulder, Kristin Ladell, James E. McLaren, David A. Price, Jamie Rossjohn, Hugh H. Reid, Frits Koning
Journal: The Journal of Immunology
J Immunol (2015) 194 (12): 6112–6122.
https://doi.org/10.4049/jimmunol.1500161
Published: 15 June 2015
View article titled, Determinants of Gliadin-Specific T Cell Selection in Celiac Disease
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Includes: Supplementary data
Journal Articles

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

Henrik N. Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung’u, Søren Buus, David A. Price, Philip J. Goulder
Journal: The Journal of Immunology
J Immunol (2015) 194 (11): 5329–5345.
https://doi.org/10.4049/jimmunol.1400854
Published: 01 June 2015
View article titled, CD8<sup>+</sup> TCR Bias and Immunodominance in HIV-1 Infection
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Includes: Supplementary data
Journal Articles

Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations

Brenna J. Hill, Patricia A. Darrah, Zachary Ende, David R. Ambrozak, Kylie M. Quinn, Sam Darko, Emma Gostick, Linda Wooldridge, Hugo A. van den Berg, Vanessa Venturi, Martin Larsen, Miles P. Davenport, Robert A. Seder, David A. Price, Daniel C. Douek
Journal: The Journal of Immunology
J Immunol (2014) 193 (11): 5626–5636.
https://doi.org/10.4049/jimmunol.1401017
Published: 01 December 2014
View article titled, Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations
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Includes: Supplementary data
Journal Articles

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

Geraldine M. O’Connor, Julian P. Vivian, Jacqueline M. Widjaja, John S. Bridgeman, Emma Gostick, Bernard A. P. Lafont, Stephen K. Anderson, David A. Price, Andrew G. Brooks, Jamie Rossjohn, Daniel W. McVicar
Journal: The Journal of Immunology
J Immunol (2014) 192 (6): 2875–2884.
https://doi.org/10.4049/jimmunol.1303142
Published: 15 March 2014
View article titled, Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity
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Includes: Supplementary data
Journal Articles

Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization

Kylie M. Quinn, Andreia Da Costa, Ayako Yamamoto, Dana Berry, Ross W. B. Lindsay, Patricia A. Darrah, Lingshu Wang, Cheng Cheng, Wing-Pui Kong, Jason G. D. Gall, Alfredo Nicosia, Antonella Folgori, Stefano Colloca, Riccardo Cortese, Emma Gostick, David A. Price, Carmen E. Gomez, Mariano Esteban, Linda S. Wyatt, Bernard Moss, Cecilia Morgan, Mario Roederer, Robert T. Bailer, Gary J. Nabel, Richard A. Koup, Robert A. Seder
Journal: The Journal of Immunology
J Immunol (2013) 190 (6): 2720–2735.
https://doi.org/10.4049/jimmunol.1202861
Published: 15 March 2013
View article titled, Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8<sup>+</sup> T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization
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Includes: Supplementary data
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CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

Dan Koning, Ana I. Costa, Ilka Hoof, John J. Miles, Nening M. Nanlohy, Kristin Ladell, Katherine K. Matthews, Vanessa Venturi, Ingrid M. M. Schellens, Jose A. M. Borghans, Can Keşmir, David A. Price, Debbie van Baarle
Journal: The Journal of Immunology
J Immunol (2013) 190 (3): 931–939.
https://doi.org/10.4049/jimmunol.1202466
Published: 01 February 2013
View article titled, CD8<sup>+</sup> TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex
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Includes: Supplementary data