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David L. Wiest
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Journal Articles

Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis

Shawn P. Fahl, Robert Sertori, Yong Zhang, Alejandra V. Contreras, Bryan Harris, Minshi Wang, Jacqueline Perrigoue, Siddharth Balachandran, Brian K. Kennedy, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2022) 208 (4): 870–880.
https://doi.org/10.4049/jimmunol.2100668
Published: 15 February 2022
View article titled, Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis
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Includes: Supplementary data
Journal Articles

Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity

Baojun Zhang, Anjun Jiao, Meifang Dai, David L. Wiest, Yuan Zhuang
Journal: The Journal of Immunology
J Immunol (2018) 201 (5): 1452–1459.
https://doi.org/10.4049/jimmunol.1800106
Published: 01 September 2018
View article titled, Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity
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Includes: Supplementary data
Journal Articles

Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B

Raz Somech, Atar Lev, Yu Nee Lee, Amos J. Simon, Ortal Barel, Ginette Schiby, Camila Avivi, Iris Barshack, Michele Rhodes, Jiejing Yin, Minshi Wang, Yibin Yang, Jennifer Rhodes, Nufar Marcus, Ben-Zion Garty, Jerry Stein, Ninette Amariglio, Gideon Rechavi, David L. Wiest, Yong Zhang
Journal: The Journal of Immunology
J Immunol (2017) 199 (12): 4036–4045.
https://doi.org/10.4049/jimmunol.1700460
Published: 15 December 2017
View article titled, Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in <em>ARPC1B</em>
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Includes: Supplementary data
Journal Articles

Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling

Nehal R. Solanki, Jason E. Stadanlick, Yong Zhang, Ann-Cecile Duc, Sang-Yun Lee, Jens Peter Holst Lauritsen, Zhiqiang Zhang, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2016) 197 (6): 2280–2289.
https://doi.org/10.4049/jimmunol.1600815
Published: 15 September 2016
View article titled, Rpl22 Loss Selectively Impairs αβ T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling
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Includes: Supplementary data
Journal Articles

Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint

Shawn P. Fahl, Bryan Harris, Francis Coffey, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2015) 194 (1): 200–209.
https://doi.org/10.4049/jimmunol.1402242
Published: 01 January 2015
View article titled, Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint
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Includes: Supplementary data
Journal Articles

Origins of γδ T Cell Effector Subsets: A Riddle Wrapped in an Enigma

In Special Collection:
Brief Reviews
Shawn P. Fahl, Francis Coffey, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2014) 193 (9): 4289–4294.
https://doi.org/10.4049/jimmunol.1401813
Published: 01 November 2014
View article titled, Origins of γδ T Cell Effector Subsets: A Riddle Wrapped in an Enigma
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Journal Articles

A Role for Ly108 in the Induction of Promyelocytic Zinc Finger Transcription Factor in Developing Thymocytes

Mala Dutta, Zachary J. Kraus, Julio Gomez-Rodriguez, Sun-hee Hwang, Jennifer L. Cannons, Jun Cheng, Sang-Yun Lee, David L. Wiest, Edward K. Wakeland, Pamela L. Schwartzberg
Journal: The Journal of Immunology
J Immunol (2013) 190 (5): 2121–2128.
https://doi.org/10.4049/jimmunol.1202145
Published: 01 March 2013
View article titled, A Role for Ly108 in the Induction of Promyelocytic Zinc Finger Transcription Factor in Developing Thymocytes
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Includes: Supplementary data
Journal Articles

Tcra Enhancer Activation by Inducible Transcription Factors Downstream of Pre-TCR Signaling

Beatriz del Blanco, Alberto García-Mariscal, David L. Wiest, Cristina Hernández-Munain
Journal: The Journal of Immunology
J Immunol (2012) 188 (7): 3278–3293.
https://doi.org/10.4049/jimmunol.1100271
Published: 01 April 2012
View article titled, <em>Tcra</em> Enhancer Activation by Inducible Transcription Factors Downstream of Pre-TCR Signaling
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Includes: Supplementary data
Journal Articles

Developmental Arrest of T Cells in Rpl22-Deficient Mice Is Dependent upon Multiple p53 Effectors

Jason E. Stadanlick, Zhiqiang Zhang, Sang-Yun Lee, Mike Hemann, Matthew Biery, Michael O. Carleton, Gerard P. Zambetti, Stephen J. Anderson, Tamas Oravecz, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2011) 187 (2): 664–675.
https://doi.org/10.4049/jimmunol.1100029
Published: 15 July 2011
View article titled, Developmental Arrest of T Cells in Rpl22-Deficient Mice Is Dependent upon Multiple p53 Effectors
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Journal Articles

Cutting Edge: Intrinsic Programming of Thymic γδT Cells for Specific Peripheral Tissue Localization

Yan Jin, Mingcan Xia, Christina M. Saylor, Kavitha Narayan, Joonsoo Kang, David L. Wiest, Yanming Wang, Na Xiong
Journal: The Journal of Immunology
J Immunol (2010) 185 (12): 7156–7160.
https://doi.org/10.4049/jimmunol.1002781
Published: 15 December 2010
View article titled, Cutting Edge: Intrinsic Programming of Thymic γδT Cells for Specific Peripheral Tissue Localization
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Includes: Supplementary data
Journal Articles

Differential Roles of IL-2–Inducible T Cell Kinase-Mediated TCR Signals in Tissue-Specific Localization and Maintenance of Skin Intraepithelial T Cells

Mingcan Xia, Qian Qi, Yan Jin, David L. Wiest, Avery August, Na Xiong
Journal: The Journal of Immunology
J Immunol (2010) 184 (12): 6807–6814.
https://doi.org/10.4049/jimmunol.1000453
Published: 15 June 2010
View article titled, Differential Roles of IL-2–Inducible T Cell Kinase-Mediated TCR Signals in Tissue-Specific Localization and Maintenance of Skin Intraepithelial T Cells
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Includes: Supplementary data
Journal Articles

Identification of the Last Cog in a Ligand-Independent Signaling Machine?

In Special Collection:
Pillars of Immunology
David L. Wiest
Journal: The Journal of Immunology
J Immunol (2009) 182 (9): 5163–5164.
https://doi.org/10.4049/jimmunol.0990028
Published: 01 May 2009
View article titled, Identification of the <em>Last</em> Cog in a Ligand-Independent Signaling Machine?
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Journal Articles

Pre-TCR-Induced β-Catenin Facilitates Traversal through β-Selection

Mai Xu, Archna Sharma, David L. Wiest, Jyoti Misra Sen
Journal: The Journal of Immunology
J Immunol (2009) 182 (2): 751–758.
https://doi.org/10.4049/jimmunol.182.2.751
Published: 15 January 2009
View article titled, Pre-TCR-Induced β-Catenin Facilitates Traversal through β-Selection
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Journal Articles

Sustained Expression of Pre-TCR Induced β-Catenin in Post-β-Selection Thymocytes Blocks T Cell Development

Mai Xu, Archna Sharma, M. Zulfiquer Hossain, David L. Wiest, Jyoti Misra Sen
Journal: The Journal of Immunology
J Immunol (2009) 182 (2): 759–765.
https://doi.org/10.4049/jimmunol.182.2.759
Published: 15 January 2009
View article titled, Sustained Expression of Pre-TCR Induced β-Catenin in Post-β-Selection Thymocytes Blocks T Cell Development
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Journal Articles

Egr2 Is Required for Bcl-2 Induction during Positive Selection

Jens-Peter Holst Lauritsen, Sridevi Kurella, Sang-Yun Lee, Juliette M. Lefebvre, Michele Rhodes, José Alberola-Ila, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2008) 181 (11): 7778–7785.
https://doi.org/10.4049/jimmunol.181.11.7778
Published: 01 December 2008
View article titled, Egr2 Is Required for Bcl-2 Induction during Positive Selection
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Journal Articles

Early Growth Response Genes Regulate B Cell Development, Proliferation, and Immune Response

Murali Gururajan, Alan Simmons, Trivikram Dasu, Brett T. Spear, Christopher Calulot, Darrell A. Robertson, David L. Wiest, John G. Monroe, Subbarao Bondada
Journal: The Journal of Immunology
J Immunol (2008) 181 (7): 4590–4602.
https://doi.org/10.4049/jimmunol.181.7.4590
Published: 01 October 2008
View article titled, Early Growth Response Genes Regulate B Cell Development, Proliferation, and Immune Response
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Journal Articles

Early Growth Response 1 and NF-ATc1 Act in Concert to Promote Thymocyte Development beyond the β-Selection Checkpoint

Ekaterina K. Koltsova, Maria Ciofani, Robert Benezra, Toru Miyazaki, Neil Clipstone, Juan Carlos Zúñiga-Pflücker, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2007) 179 (7): 4694–4703.
https://doi.org/10.4049/jimmunol.179.7.4694
Published: 01 October 2007
View article titled, Early Growth Response 1 and NF-ATc1 Act in Concert to Promote Thymocyte Development beyond the β-Selection Checkpoint
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Journal Articles

Redundant Role for Early Growth Response Transcriptional Regulators in Thymocyte Differentiation and Survival

John H. Carter, Juliet M. Lefebvre, David L. Wiest, Warren G. Tourtellotte
Journal: The Journal of Immunology
J Immunol (2007) 178 (11): 6796–6805.
https://doi.org/10.4049/jimmunol.178.11.6796
Published: 01 June 2007
View article titled, Redundant Role for Early Growth Response Transcriptional Regulators in Thymocyte Differentiation and Survival
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Includes: Supplementary data
Journal Articles

Unequal Contribution of Akt Isoforms in the Double-Negative to Double-Positive Thymocyte Transition

Changchuin Mao, Esmerina G. Tili, Marei Dose, Mariëlle C. Haks, Susan E. Bear, Ioanna Maroulakou, Kyoji Horie, George A. Gaitanaris, Vincenzo Fidanza, Thomas Ludwig, David L. Wiest, Fotini Gounari, Philip N. Tsichlis
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5443–5453.
https://doi.org/10.4049/jimmunol.178.9.5443
Published: 01 May 2007
View article titled, Unequal Contribution of Akt Isoforms in the Double-Negative to Double-Positive Thymocyte Transition
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Journal Articles

Enforced Expression of Spi-B Reverses T Lineage Commitment and Blocks β-Selection

Juliette M. Lefebvre, Mariëlle C. Haks, Michael O. Carleton, Michele Rhodes, Gomathinayagam Sinnathamby, M. Celeste Simon, Laurence C. Eisenlohr, Lee Ann Garrett-Sinha, David L. Wiest
Journal: The Journal of Immunology
J Immunol (2005) 174 (10): 6184–6194.
https://doi.org/10.4049/jimmunol.174.10.6184
Published: 15 May 2005
View article titled, Enforced Expression of Spi-B Reverses T Lineage Commitment and Blocks β-Selection
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