1-20 of 25
Defu Zeng
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Tc17 cells cause gut graft-versus-host disease through induction of dysbiosis and depletion of CX3CR1hi phagocytes

Qingxiao Song, Xiaoning Wang, Xiwei Wu, Hanjun Qin, Dongchang Zhao, Robert R Jenq, Marcel RM Van Den Brink, Arthur D. Riggs, Paul J Martin, Yuanzhong Chen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 87.7.
https://doi.org/10.4049/jimmunol.204.Supp.87.7
Published: 01 May 2020
View article titled, Tc17 cells cause gut graft-versus-host disease through induction of dysbiosis and depletion of CX3CR1hi phagocytes
Add to Citation Manager
Journal Articles

Blockade of CD80 interaction with PD-L1 between T and tumor cells augments effector T expansion and tumor immunity in a PD-1-dependent manner

YUANKUN ZHANG, Kaniel Cassady, Michael Lee, Ubaydah Nasri, Arthur D. Riggs, Ru Feng, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 165.20.
https://doi.org/10.4049/jimmunol.204.Supp.165.20
Published: 01 May 2020
View article titled, Blockade of CD80 interaction with PD-L1 between T and tumor cells augments effector T expansion and tumor immunity in a PD-1-dependent manner
Add to Citation Manager
Journal Articles

Neutralization of IL-2 prevents acute GVHD while preserving GVL activity via regulating PD-L1/PD-1 signaling

Qingxiao Song, Xiaoning Wang, Paul J. Martin, Yuanzhong Chen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 69.11.
https://doi.org/10.4049/jimmunol.202.Supp.69.11
Published: 01 May 2019
View article titled, Neutralization of IL-2 prevents acute GVHD while preserving GVL activity via regulating PD-L1/PD-1 signaling
Add to Citation Manager
Journal Articles

Tc17 cells mediate gut GVHD via IL-22 and dysbiosis

Qingxiao Song, Xiwei Wu, Deye Zeng, Robert R. Jenq, Marcel R. M. Van den Brink, Arthur D. Riggs, Yuanzhong chen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 55.42.
https://doi.org/10.4049/jimmunol.200.Supp.55.42
Published: 01 May 2018
View article titled, Tc17 cells mediate gut GVHD via IL-22 and dysbiosis
Add to Citation Manager
Journal Articles

MicroRNA-142 guards against autoimmunity by controlling Treg cell development and function

Wei-Le Wang, Ching Ouyang, Kaniel Cassady, Min Xiong, Estefany Reyes, Alicia Davis, Kathie Tang, Defu Zeng, Mark Boldin
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 101.2.
https://doi.org/10.4049/jimmunol.200.Supp.101.2
Published: 01 May 2018
View article titled, <em>MicroRNA-142</em> guards against autoimmunity by controlling T<sub>reg</sub> cell development and function
Add to Citation Manager
Journal Articles

Induction of Haploidentical Mixed Chimerism Cures Autoimmune Type 1 Diabetes

Yuqing Liu, Mingfeng Zhang, Arthur Riggs, Xi Zhang, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 176.16.
https://doi.org/10.4049/jimmunol.200.Supp.176.16
Published: 01 May 2018
View article titled, Induction of Haploidentical Mixed Chimerism Cures Autoimmune Type 1 Diabetes
Add to Citation Manager
Journal Articles

IFN-γ-deficient transplant induces acute gut GVHD via dysregulation of RagIIIγ and intestinal microbiota

Qingxiao Song, Veronica zeng, Xiwei Wu, Arthur D. Riggs, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 82.10.
https://doi.org/10.4049/jimmunol.198.Supp.82.10
Published: 01 May 2017
View article titled, IFN-γ-deficient transplant induces acute gut GVHD via dysregulation of RagIIIγ and intestinal microbiota
Add to Citation Manager
Journal Articles

PD-L1/CD80 interaction differentially regulates CD8+ T cell metabolism, survival and GVHD capacity in the presence or absence of PD-1

Kaniel Cassady, Qingxiao Song, Yuankun Zhang, Paul J. Martin, David Ann, Arthur D. Riggs, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 82.5.
https://doi.org/10.4049/jimmunol.198.Supp.82.5
Published: 01 May 2017
View article titled, PD-L1/CD80 interaction differentially regulates CD8<sup>+</sup> T cell metabolism, survival and GVHD capacity in the presence or absence of PD-1
Add to Citation Manager
Journal Articles

Transient depletion of donor CD4+ T cells early after HCT allows recipient tissue PD-L1 to tolerize infiltrating CD8+ T cells and to prevent acute GVHD while preserving GVL effect

qingxiao song, Xiong Ni, Kaniel Cassady, Ruishu Deng, Hua Jin, Mingfeng Zhang, Stephen Forman, Paul Martin, Jianmin Wang, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 140.13.
https://doi.org/10.4049/jimmunol.196.Supp.140.13
Published: 01 May 2016
View article titled, Transient depletion of donor CD4<sup>+</sup> T cells early after HCT allows recipient tissue PD-L1 to tolerize infiltrating CD8<sup>+</sup> T cells and to prevent acute GVHD while preserving GVL effect
Add to Citation Manager
Journal Articles

MHC-mismatched but not matched mixed chimerism can tolerize peripheral non-cross-reactive autoreactive T cells in type 1 diabetic NOD mice

Mingfeng Zhang, Jeremy Racine, Yuqing Liu, Qing Lin, Tong Qi, Tiankun Wang, Arthur D. Riggs, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 186.19.
https://doi.org/10.4049/jimmunol.196.Supp.186.19
Published: 01 May 2016
View article titled, MHC-mismatched but not matched mixed chimerism can tolerize peripheral non-cross-reactive autoreactive T cells in type 1 diabetic NOD mice
Add to Citation Manager
Journal Articles

MHC-mismatched mixed chimerism augments thymic regulatory T cell production and prevents relapse of EAE (THER7P.960)

Li-Min Wu, Nainong Li, Mingfeng Zhang, Shengli Xue, Arthur Riggs, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 208.20.
https://doi.org/10.4049/jimmunol.194.Supp.208.20
Published: 01 May 2015
View article titled, MHC-mismatched mixed chimerism augments thymic regulatory T cell production and prevents relapse of EAE (THER7P.960)
Add to Citation Manager
Journal Articles

B7H1/CD80 Interaction Augments PD-1–Dependent T Cell Apoptosis and Ameliorates Graft-versus-Host Disease

Ruishu Deng, Kaniel Cassady, Xiaofan Li, Sheng Yao, Mingfeng Zhang, Jeremy Racine, Jeffrey Lin, Lieping Chen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2015) 194 (2): 560–574.
https://doi.org/10.4049/jimmunol.1402157
Published: 15 January 2015
View article titled, B7H1/CD80 Interaction Augments PD-1–Dependent T Cell Apoptosis and Ameliorates Graft-versus-Host Disease
Open the PDF for B7H1/CD80 Interaction Augments PD-1–Dependent T Cell Apoptosis and Ameliorates Graft-versus-Host Disease in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

MHC-Mismatched Mixed Chimerism Mediates Thymic Deletion of Cross-Reactive Autoreactive T Cells and Prevents Insulitis in Nonobese Diabetic Mice

Jeremy J. Racine, Mingfeng Zhang, Miao Wang, William Morales, Christine Shen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2015) 194 (1): 407–417.
https://doi.org/10.4049/jimmunol.1401584
Published: 01 January 2015
View article titled, MHC-Mismatched Mixed Chimerism Mediates Thymic Deletion of Cross-Reactive Autoreactive T Cells and Prevents Insulitis in Nonobese Diabetic Mice
Open the PDF for MHC-Mismatched Mixed Chimerism Mediates Thymic Deletion of Cross-Reactive Autoreactive T Cells and Prevents Insulitis in Nonobese Diabetic Mice in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

MHC-Mismatched Chimerism Is Required for Induction of Transplantation Tolerance in Autoimmune Nonobese Diabetic Recipients

Miao Wang, Jeremy Racine, Mingfeng Zhang, Tao Wu, Ruishu Deng, Heather Johnston, Christine Shen, Kathleen Siswanto, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2014) 193 (4): 2005–2015.
https://doi.org/10.4049/jimmunol.1401137
Published: 15 August 2014
View article titled, MHC-Mismatched Chimerism Is Required for Induction of Transplantation Tolerance in Autoimmune Nonobese Diabetic Recipients
Open the PDF for MHC-Mismatched Chimerism Is Required for Induction of Transplantation Tolerance in Autoimmune Nonobese Diabetic Recipients in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells

Tao Wu, James S. Young, Heather Johnston, Xiong Ni, Ruishu Deng, Jeremy Racine, Miao Wang, Audrey Wang, Ivan Todorov, Jianmin Wang, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2013) 191 (1): 488–499.
https://doi.org/10.4049/jimmunol.1300657
Published: 01 July 2013
View article titled, Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4<sup>+</sup> and CD8<sup>+</sup> T Cells
Open the PDF for Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4<sup>+</sup> and CD8<sup>+</sup> T Cells in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease

James S. Young, Tao Wu, Yuhong Chen, Dongchang Zhao, Hongjun Liu, Tangsheng Yi, Heather Johnston, Jeremy Racine, Xiaofan Li, Audrey Wang, Ivan Todorov, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2012) 189 (1): 222–233.
https://doi.org/10.4049/jimmunol.1200677
Published: 01 July 2012
View article titled, Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4<sup>+</sup> T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease
Open the PDF for Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4<sup>+</sup> T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Loss of B7-H1 Expression by Recipient Parenchymal Cells Leads to Expansion of Infiltrating Donor CD8+ T Cells and Persistence of Graft-Versus-Host Disease

Xiaofan Li, Ruishu Deng, Wei He, Can Liu, Miao Wang, James Young, Zhipeng Meng, Chantal Du, Wendong Huang, Lieping Chen, Yuanzhong Chen, Paul Martin, Stephen Forman, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2012) 188 (2): 724–734.
https://doi.org/10.4049/jimmunol.1102630
Published: 15 January 2012
View article titled, Loss of B7-H1 Expression by Recipient Parenchymal Cells Leads to Expansion of Infiltrating Donor CD8<sup>+</sup> T Cells and Persistence of Graft-Versus-Host Disease
Open the PDF for Loss of B7-H1 Expression by Recipient Parenchymal Cells Leads to Expansion of Infiltrating Donor CD8<sup>+</sup> T Cells and Persistence of Graft-Versus-Host Disease in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients

Tangsheng Yi, Xiaofan Li, Sheng Yao, Lin Wang, Yuhong Chen, Dongchang Zhao, Heather F. Johnston, James S. Young, Hongjun Liu, Ivan Todorov, Stephen J. Forman, Lieping Chen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2011) 186 (5): 2739–2749.
https://doi.org/10.4049/jimmunol.1002939
Published: 01 March 2011
View article titled, Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients
Open the PDF for Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Alloimmune Response Results in Expansion of Autoreactive Donor CD4+ T Cells in Transplants That Can Mediate Chronic Graft-versus-Host Disease

Dongchang Zhao, James S. Young, Yu-Hong Chen, Elizabeth Shen, Tangsheng Yi, Ivan Todorov, Peiguo G. Chu, Stephen J. Forman, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2011) 186 (2): 856–868.
https://doi.org/10.4049/jimmunol.1002195
Published: 15 January 2011
View article titled, Alloimmune Response Results in Expansion of Autoreactive Donor CD4<sup>+</sup> T Cells in Transplants That Can Mediate Chronic Graft-versus-Host Disease
Open the PDF for Alloimmune Response Results in Expansion of Autoreactive Donor CD4<sup>+</sup> T Cells in Transplants That Can Mediate Chronic Graft-versus-Host Disease in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft versus host disease (141.13)

Tangsheng Yi, Ying Chen, Lin Wang, Gong Du, Daniel Huang, Dongchang zhao, James young, Ivan Todorov, Chen Lieping, Yoichiro Iwakura, Forman Stephen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 141.13.
https://doi.org/10.4049/jimmunol.182.Supp.141.13
Published: 01 April 2009
View article titled, Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft versus host disease (141.13)
Add to Citation Manager