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Detlef Zillikens
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Journal Articles

Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita

Hiroaki Iwata, Mareike Witte, Unni Krishna S. R. L. Samavedam, Yask Gupta, Atsushi Shimizu, Akira Ishiko, Tobias Schröder, Karsten Seeger, Markus Dahlke, Dirk Rades, Detlef Zillikens, Ralf J. Ludwig
Journal: The Journal of Immunology
J Immunol (2015) 195 (5): 1945–1954.
https://doi.org/10.4049/jimmunol.1501003
Published: 01 September 2015
View article titled, Radiosensitive Hematopoietic Cells Determine the Extent of Skin Inflammation in Experimental Epidermolysis Bullosa Acquisita
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Includes: Supplementary data
Journal Articles

Caspase-1–Independent IL-1 Release Mediates Blister Formation in Autoantibody-Induced Tissue Injury through Modulation of Endothelial Adhesion Molecules

Hengameh Sadeghi, Anike Lockmann, Anna-Carina Hund, Unni K. S. R. L. Samavedam, Elena Pipi, Katerina Vafia, Eva Hauenschild, Kathrin Kalies, Hendri H. Pas, Marcel F. Jonkman, Hiroaki Iwata, Andreas Recke, Michael P. Schön, Detlef Zillikens, Enno Schmidt, Ralf J. Ludwig
Journal: The Journal of Immunology
J Immunol (2015) 194 (8): 3656–3663.
https://doi.org/10.4049/jimmunol.1402688
Published: 15 April 2015
View article titled, Caspase-1–Independent IL-1 Release Mediates Blister Formation in Autoantibody-Induced Tissue Injury through Modulation of Endothelial Adhesion Molecules
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Journal Articles

Recombinant Human IgA1 and IgA2 Autoantibodies to Type VII Collagen Induce Subepidermal Blistering Ex Vivo

Andreas Recke, Luisa M. Trog, Hendri H. Pas, Artem Vorobyev, Aida Abadpour, Marcel F. Jonkman, Ger van Zandbergen, Claudia Kauderer, Detlef Zillikens, Gestur Vidarsson, Ralf J. Ludwig
Journal: The Journal of Immunology
J Immunol (2014) 193 (4): 1600–1608.
https://doi.org/10.4049/jimmunol.1400160
Published: 15 August 2014
View article titled, Recombinant Human IgA1 and IgA2 Autoantibodies to Type VII Collagen Induce Subepidermal Blistering Ex Vivo
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Includes: Supplementary data
Journal Articles

GM-CSF Modulates Autoantibody Production and Skin Blistering in Experimental Epidermolysis Bullosa Acquisita

Unni Krishna S. R. L. Samavedam, Hiroaki Iwata, Susen Müller, Franziska S. Schulze, Andreas Recke, Enno Schmidt, Detlef Zillikens, Ralf J. Ludwig
Journal: The Journal of Immunology
J Immunol (2014) 192 (2): 559–571.
https://doi.org/10.4049/jimmunol.1301556
Published: 15 January 2014
View article titled, GM-CSF Modulates Autoantibody Production and Skin Blistering in Experimental Epidermolysis Bullosa Acquisita
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Includes: Supplementary data
Journal Articles

B Cells, Dendritic Cells, and Macrophages Are Required To Induce an Autoreactive CD4 Helper T Cell Response in Experimental Epidermolysis Bullosa Acquisita

Hiroaki Iwata, Katja Bieber, Benjamin Tiburzy, Navina Chrobok, Kathrin Kalies, Atsushi Shimizu, Sarah Leineweber, Akira Ishiko, Artem Vorobyev, Detlef Zillikens, Jörg Köhl, Jürgen Westermann, Karsten Seeger, Rudolf Manz, Ralf J. Ludwig
Journal: The Journal of Immunology
J Immunol (2013) 191 (6): 2978–2988.
https://doi.org/10.4049/jimmunol.1300310
Published: 15 September 2013
View article titled, B Cells, Dendritic Cells, and Macrophages Are Required To Induce an Autoreactive CD4 Helper T Cell Response in Experimental Epidermolysis Bullosa Acquisita
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Includes: Supplementary data
Journal Articles

Complement-Fixing Anti-Type VII Collagen Antibodies Are Induced in Th1-Polarized Lymph Nodes of Epidermolysis Bullosa Acquisita-Susceptible Mice

Christoph M. Hammers, Katja Bieber, Kathrin Kalies, David Banczyk, Christoph T. Ellebrecht, Saleh M. Ibrahim, Detlef Zillikens, Ralf J. Ludwig, Jürgen Westermann
Journal: The Journal of Immunology
J Immunol (2011) 187 (10): 5043–5050.
https://doi.org/10.4049/jimmunol.1100796
Published: 15 November 2011
View article titled, Complement-Fixing Anti-Type VII Collagen Antibodies Are Induced in Th1-Polarized Lymph Nodes of Epidermolysis Bullosa Acquisita-Susceptible Mice
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Includes: Supplementary data
Journal Articles

Repetitive Immunization Breaks Tolerance to Type XVII Collagen and Leads to Bullous Pemphigoid in Mice

Misa Hirose, Andreas Recke, Tina Beckmann, Atsushi Shimizu, Akira Ishiko, Katja Bieber, Jürgen Westermann, Detlef Zillikens, Enno Schmidt, Ralf J. Ludwig
Journal: The Journal of Immunology
J Immunol (2011) 187 (3): 1176–1183.
https://doi.org/10.4049/jimmunol.1100596
Published: 01 August 2011
View article titled, Repetitive Immunization Breaks Tolerance to Type XVII Collagen and Leads to Bullous Pemphigoid in Mice
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Journal Articles

T Cells Are Required for the Production of Blister-Inducing Autoantibodies in Experimental Epidermolysis Bullosa Acquisita

Ana Gabriela Sitaru, Alina Sesarman, Sidonia Mihai, Mircea T. Chiriac, Detlef Zillikens, Per Hultman, Werner Solbach, Cassian Sitaru
Journal: The Journal of Immunology
J Immunol (2010) 184 (3): 1596–1603.
https://doi.org/10.4049/jimmunol.0901412
Published: 28 December 2009
View article titled, T Cells Are Required for the Production of Blister-Inducing Autoantibodies in Experimental Epidermolysis Bullosa Acquisita
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Includes: Supplementary data
Journal Articles

Pemphigus Vulgaris IgG Directly Inhibit Desmoglein 3-Mediated Transinteraction

Wolfgang-Moritz Heupel, Detlef Zillikens, Detlev Drenckhahn, Jens Waschke
Journal: The Journal of Immunology
J Immunol (2008) 181 (3): 1825–1834.
https://doi.org/10.4049/jimmunol.181.3.1825
Published: 01 August 2008
View article titled, Pemphigus Vulgaris IgG Directly Inhibit Desmoglein 3-Mediated Transinteraction
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Journal Articles

The Alternative Pathway of Complement Activation Is Critical for Blister Induction in Experimental Epidermolysis Bullosa Acquisita

Sidonia Mihai, Mircea T. Chiriac, Kazue Takahashi, Joshua M. Thurman, V. Michael Holers, Detlef Zillikens, Marina Botto, Cassian Sitaru
Journal: The Journal of Immunology
J Immunol (2007) 178 (10): 6514–6521.
https://doi.org/10.4049/jimmunol.178.10.6514
Published: 15 May 2007
View article titled, The Alternative Pathway of Complement Activation Is Critical for Blister Induction in Experimental Epidermolysis Bullosa Acquisita
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Journal Articles

Induction of Complement-Fixing Autoantibodies against Type VII Collagen Results in Subepidermal Blistering in Mice

Cassian Sitaru, Mircea T. Chiriac, Sidonia Mihai, Jürgen Büning, Andreas Gebert, Akira Ishiko, Detlef Zillikens
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 3461–3468.
https://doi.org/10.4049/jimmunol.177.5.3461
Published: 01 September 2006
View article titled, Induction of Complement-Fixing Autoantibodies against Type VII Collagen Results in Subepidermal Blistering in Mice
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Journal Articles

Macrophages, But Not T and B Lymphocytes, Are Critical for Subepidermal Blister Formation in Experimental Bullous Pemphigoid: Macrophage-Mediated Neutrophil Infiltration Depends on Mast Cell Activation

Ruoyan Chen, Janet A. Fairley, Ming-Lang Zhao, George J. Giudice, Detlef Zillikens, Luis A. Diaz, Zhi Liu
Journal: The Journal of Immunology
J Immunol (2002) 169 (7): 3987–3992.
https://doi.org/10.4049/jimmunol.169.7.3987
Published: 01 October 2002
View article titled, Macrophages, But Not T and B Lymphocytes, Are Critical for Subepidermal Blister Formation in Experimental Bullous Pemphigoid: Macrophage-Mediated Neutrophil Infiltration Depends on Mast Cell Activation
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