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Edward K. Wakeland
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Journal Articles

Longitudinal Immune and Genomic Monitoring Reveals Signatures of Immune-related Adverse Events in Cancer Patients Receiving Checkpoint Inhibitor Therapy

Free
Shaheen Khan, Angela Moses, Marjaan Imam, Edward K Wakeland, Carlos Arana, Farjana Fattah, Quan-Zhen Li, Mitch von Itzstein, David Hsieh, Vinitha Popat, Spencer Barnes, Yang Xie, Saad Khan, David Gerber
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 145.28.
https://doi.org/10.4049/jimmunol.204.Supp.145.28
Published: 01 May 2020
View articletitled, Longitudinal Immune and Genomic Monitoring Reveals Signatures of Immune-related Adverse Events in Cancer Patients Receiving Checkpoint Inhibitor Therapy
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Journal Articles

Serum Antibody Profiling Healthy Toddlers Reveals Low, Intermediate and High Response Cohorts

Free
Nicolai S van Oers, Patricia Pichilingue-Reto, Prithvi Raj, Igor Dozmorov, Quan_Zhen Li, Edward K Wakeland, Nancy Kelly, M. Teresa Teresa de la Morena
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 120.9.
https://doi.org/10.4049/jimmunol.202.Supp.120.9
Published: 01 May 2019
View articletitled, Serum Antibody Profiling Healthy Toddlers Reveals Low, Intermediate and High Response Cohorts
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Journal Articles

T cell intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells

Free
Aakanksha Jain, Ran Song, Edward K. Wakeland, Chandrashekhar Pasare
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 110.8.
https://doi.org/10.4049/jimmunol.200.Supp.110.8
Published: 01 May 2018
View articletitled, T cell intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells
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Journal Articles

Chromatin accessibility modulates the induction of innate immunity in cells of myeloid lineage.

Free
Ran Song, Igor Dozmorov, Benjamin Wakeland, Carlos Arana, Chaoying Liang, Bo Zhang, Jinchun Zhou, Chandrashekhar Pasare, Edward K. Wakeland
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 109.24.
https://doi.org/10.4049/jimmunol.200.Supp.109.24
Published: 01 May 2018
View articletitled, Chromatin accessibility modulates the induction of innate immunity in cells of myeloid lineage.
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Journal Articles

Transcriptional profiling of pathogen-specific CD4 T cells reveals key events that regulate Th17 cell priming and differentiation

Free
Yajing Gao, Krystin L. Deason, Aakanksha Jain, Igor Dozmorov, Edward K. Wakeland, Chandrashekhar Pasare
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 47.7.
https://doi.org/10.4049/jimmunol.200.Supp.47.7
Published: 01 May 2018
View articletitled, Transcriptional profiling of pathogen-specific CD4 T cells reveals key events that regulate Th17 cell priming and differentiation
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Journal Articles

Profiling Serum Antibody Specificities in Infants Reveals a Significant Number with Autoreactive Antibodies

Free
Nicolai S. van Oers, Prithvi Raj, Patricia Pichilingue-Reto, Igor Dozmorov, M. Teresa de la Morena, Edward K. Wakeland
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 45.31.
https://doi.org/10.4049/jimmunol.200.Supp.45.31
Published: 01 May 2018
View articletitled, Profiling Serum Antibody Specificities in Infants Reveals a Significant Number with Autoreactive Antibodies
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Journal Articles

Identification of Btnl2 as a Key Gene in Suppressing Autoimmunity: New Players in SLE pathogenesis

Free
Shaheen Khan, Sun-Hee Hwang, Katherine Belobrajdic, Kasthuribai Viswanathan, Benjamin Wakeland, Jose Casco, Edward K. Wakeland
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 100.3.
https://doi.org/10.4049/jimmunol.200.Supp.100.3
Published: 01 May 2018
View articletitled, Identification of Btnl2 as a Key Gene in Suppressing Autoimmunity: New Players in SLE pathogenesis
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Journal Articles

Mycobacterium tuberculosis produces small noncoding RNAs during infections to regulate mycobacterial and eukaryotic gene expression

Free
Nicolai S van Oers, Shashikant Srivastava, Prithvi Raj, Igor Dozmorov, Edward K Wakeland, Tawanda Gumbo
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 65.13.
https://doi.org/10.4049/jimmunol.196.Supp.65.13
Published: 01 May 2016
View articletitled, Mycobacterium tuberculosis produces small noncoding RNAs during infections to regulate mycobacterial and eukaryotic gene expression
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Journal Articles

Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus

Free
Simanta Pathak, Kirthi Raman Kumar, Hasna Kanta, Ferdicia Carr-Johnson, Jie Han, Anna Bashmakov, Lionel Faure, Huihua Ding, Kamala Vanarsa, Shaheen Khan, Quan-Zhen Li, Kent Chapman, Edward K. Wakeland, Chandra Mohan
Journal: The Journal of Immunology
J Immunol (2016) 196 (4): 1507–1516.
https://doi.org/10.4049/jimmunol.1500291
Published: 15 February 2016
View articletitled, Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus
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Includes: Supplementary data
Journal Articles

Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice

Open Access
Maroof Hasan, Nicole Dobbs, Shaheen Khan, Michael A. White, Edward K. Wakeland, Quan-Zhen Li, Nan Yan
Journal: The Journal of Immunology
J Immunol (2015) 195 (10): 4573–4577.
https://doi.org/10.4049/jimmunol.1500162
Published: 15 November 2015
View articletitled, Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice
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Includes: Supplementary data
Journal Articles

Pillars Article: Polygenic Control of Susceptibility to Murine Systemic Lupus Erythematosus. Immunity. 1994. 1: 219-229

Free
Laurence Morel, Ulrich H. Rudofsky, Jeffrey A. Longmate, Joel Schiffenbauer, Edward K. Wakeland
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4047–4057.
Published: 01 November 2015
View articletitled, Pillars Article: Polygenic Control of Susceptibility to Murine Systemic Lupus Erythematosus. Immunity. 1994. 1: 219-229
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Journal Articles

B Cell–Intrinsic CD84 and Ly108 Maintain Germinal Center B Cell Tolerance

Free
Eric B. Wong, Chetna Soni, Alice Y. Chan, Phillip P. Domeier, Shwetank, Thomas Abraham, Nisha Limaye, Tahsin N. Khan, Melinda J. Elias, Sathi Babu Chodisetti, Edward K. Wakeland, Ziaur S. M. Rahman
Journal: The Journal of Immunology
J Immunol (2015) 194 (9): 4130–4143.
https://doi.org/10.4049/jimmunol.1403023
Published: 01 May 2015
View articletitled, B Cell–Intrinsic CD84 and Ly108 Maintain Germinal Center B Cell Tolerance
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Includes: Supplementary data
Journal Articles

Hunting Autoimmune Disease Genes in NOD: Early Steps on a Long Road to Somewhere Important (Hopefully)

Free
In Special Collection:
Pillars of Immunology
Edward K. Wakeland
Journal: The Journal of Immunology
J Immunol (2014) 193 (1): 3–6.
https://doi.org/10.4049/jimmunol.1401200
Published: 01 July 2014
View articletitled, Hunting Autoimmune Disease Genes in NOD: Early Steps on a Long Road to Somewhere Important (Hopefully)
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Journal Articles

A Role for Ly108 in the Induction of Promyelocytic Zinc Finger Transcription Factor in Developing Thymocytes

Free
Mala Dutta, Zachary J. Kraus, Julio Gomez-Rodriguez, Sun-hee Hwang, Jennifer L. Cannons, Jun Cheng, Sang-Yun Lee, David L. Wiest, Edward K. Wakeland, Pamela L. Schwartzberg
Journal: The Journal of Immunology
J Immunol (2013) 190 (5): 2121–2128.
https://doi.org/10.4049/jimmunol.1202145
Published: 01 March 2013
View articletitled, A Role for Ly108 in the Induction of Promyelocytic Zinc Finger Transcription Factor in Developing Thymocytes
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Includes: Supplementary data
Journal Articles

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus–Prone Mice

Free
Sun-Hee Hwang, Huiyin Lee, Miwako Yamamoto, Leigh A. Jones, Jivanaah Dayalan, Richard Hopkins, Xin J. Zhou, Felix Yarovinsky, John E. Connolly, Maria A. Curotto de Lafaille, Edward K. Wakeland, Anna-Marie Fairhurst
Journal: The Journal of Immunology
J Immunol (2012) 189 (12): 5786–5796.
https://doi.org/10.4049/jimmunol.1202195
Published: 15 December 2012
View articletitled, B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus–Prone Mice
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Includes: Supplementary data
Journal Articles

Correction: Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function

Free
Idil Aktan, Alan Chant, Zachary D. Borg, David E. Damby, Paige C. Leenstra, Graham W. G. Lilley, Joseph Petty, Benjamin T. Suratt, Cory Teuscher, Edward K. Wakeland, Matthew E. Poynter, Jonathan E. Boyson
Journal: The Journal of Immunology
J Immunol (2011) 187 (6): 3450.
https://doi.org/10.4049/jimmunol.1190052
Published: 15 September 2011
View articletitled, Correction: Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function
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Journal Articles

Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function

Free
Idil Aktan, Alan Chant, Zachary D. Borg, David E. Damby, Paige C. Leenstra, Graham W. G. Lilley, Joseph Petty, Benjamin T. Suratt, Cory Teuscher, Edward K. Wakeland, Matthew E. Poynter, Jonathan E. Boyson
Journal: The Journal of Immunology
J Immunol (2010) 185 (1): 144–156.
https://doi.org/10.4049/jimmunol.0902658
Published: 01 July 2010
View articletitled, Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function
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Journal Articles

Type I Interferons Produced by Resident Renal Cells May Promote End-Organ Disease in Autoantibody-Mediated Glomerulonephritis

Free
Anna-Marie Fairhurst, Chun Xie, Yuyang Fu, Andrew Wang, Christopher Boudreaux, Xin J. Zhou, Ricardo Cibotti, Anthony Coyle, John E. Connolly, Edward K. Wakeland, Chandra Mohan
Journal: The Journal of Immunology
J Immunol (2009) 183 (10): 6831–6838.
https://doi.org/10.4049/jimmunol.0900742
Published: 15 November 2009
View articletitled, Type I Interferons Produced by Resident Renal Cells May Promote End-Organ Disease in Autoantibody-Mediated Glomerulonephritis
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Journal Articles

CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus

Free
Andrew Wang, Anna-Marie Fairhurst, Katalin Tus, Srividya Subramanian, Yang Liu, Fangming Lin, Peter Igarashi, Xin J. Zhou, Frederic Batteux, Donald Wong, Edward K. Wakeland, Chandra Mohan
Journal: The Journal of Immunology
J Immunol (2009) 182 (7): 4448–4458.
https://doi.org/10.4049/jimmunol.0801920
Published: 01 April 2009
View articletitled, CXCR4/CXCL12 Hyperexpression Plays a Pivotal Role in the Pathogenesis of Lupus
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Includes: Supplementary data
Journal Articles

Mapping of Quantitative Trait Loci Determining NK Cell-Mediated Resistance to MHC Class I-Deficient Bone Marrow Grafts in Perforin-Deficient Mice

Free
Maria H. Johansson, Mesha A. Taylor, Maja Jagodic, Katalin Tus, John D. Schatzle, Edward K. Wakeland, Michael Bennett
Journal: The Journal of Immunology
J Immunol (2006) 177 (11): 7923–7929.
https://doi.org/10.4049/jimmunol.177.11.7923
Published: 01 December 2006
View articletitled, Mapping of Quantitative Trait Loci Determining NK Cell-Mediated Resistance to MHC Class I-Deficient Bone Marrow Grafts in Perforin-Deficient Mice
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