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Egil Lien
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Journal Articles

Role of innate signaling pathways in the regulation of antiviral IgG2c responses (108.9)

Forum Raval, Egil Lien, Paula Pitha, Eva Szomolanyi-Tsuda
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 108.9.
https://doi.org/10.4049/jimmunol.188.Supp.108.9
Published: 01 May 2012
View article titled, Role of innate signaling pathways in the regulation of antiviral IgG2c responses (108.9)
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Journal Articles

Adjuvant-dependent cytokine profiles in the context of a DNA prime-protein boost HIV vaccine (113.23)

Rachel Buglione-Corbett, Kim Pouliot, Robyn Marty-Roix, Kim West, Shixia Wang, Egil Lien, Shan Lu
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 113.23.
https://doi.org/10.4049/jimmunol.188.Supp.113.23
Published: 01 May 2012
View article titled, Adjuvant-dependent cytokine profiles in the context of a DNA prime-protein boost HIV vaccine (113.23)
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Journal Articles

Inflammation and Fibrosis during Chlamydia pneumoniae Infection Is Regulated by IL-1 and the NLRP3/ASC Inflammasome

Xianbao He, Samrawit Mekasha, Nikolaos Mavrogiorgos, Katherine A. Fitzgerald, Egil Lien, Robin R. Ingalls
Journal: The Journal of Immunology
J Immunol (2010) 184 (10): 5743–5754.
https://doi.org/10.4049/jimmunol.0903937
Published: 15 May 2010
View article titled, Inflammation and Fibrosis during <em>Chlamydia pneumoniae</em> Infection Is Regulated by IL-1 and the NLRP3/ASC Inflammasome
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Journal Articles

TLR4 Is a Negative Regulator in Noninfectious Lung Inflammation

Hang Zhao, Shaw-Wei Leu, Liyun Shi, Rejmon Dedaj, Gaofeng Zhao, Hari G. Garg, Lianjun Shen, Egil Lien, Katherine A. Fitzgerald, Aviva Shiedlin, Huahao Shen, Deborah A. Quinn, Charles A. Hales
Journal: The Journal of Immunology
J Immunol (2010) 184 (9): 5308–5314.
https://doi.org/10.4049/jimmunol.1000009
Published: 01 May 2010
View article titled, TLR4 Is a Negative Regulator in Noninfectious Lung Inflammation
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Journal Articles

Yersinia pestis Evades TLR4-dependent Induction of IL-12(p40)2 by Dendritic Cells and Subsequent Cell Migration

Richard T. Robinson, Shabaana A. Khader, Richard M. Locksley, Egil Lien, Stephen T. Smiley, Andrea M. Cooper
Journal: The Journal of Immunology
J Immunol (2008) 181 (8): 5560–5567.
https://doi.org/10.4049/jimmunol.181.8.5560
Published: 15 October 2008
View article titled, <em>Yersinia pestis</em> Evades TLR4-dependent Induction of IL-12(p40)<sub>2</sub> by Dendritic Cells and Subsequent Cell Migration
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Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with Trypanosoma cruzi

Daniella C. Bartholomeu, Catherine Ropert, Mariane B. Melo, Peggy Parroche, Caroline F. Junqueira, Santuza M. R. Teixeira, Cherilyn Sirois, Pia Kasperkovitz, Cathrine F. Knetter, Egil Lien, Eicke Latz, Douglas T. Golenbock, Ricardo T. Gazzinelli
Journal: The Journal of Immunology
J Immunol (2008) 181 (2): 1333–1344.
https://doi.org/10.4049/jimmunol.181.2.1333
Published: 15 July 2008
View article titled, Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with <em>Trypanosoma cruzi</em>
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Journal Articles

MyD88- and Bruton’s Tyrosine Kinase-Mediated Signals Are Essential for T Cell-Independent Pathogen-Specific IgM Responses

Kishore R. Alugupalli, Shizuo Akira, Egil Lien, John M. Leong
Journal: The Journal of Immunology
J Immunol (2007) 178 (6): 3740–3749.
https://doi.org/10.4049/jimmunol.178.6.3740
Published: 15 March 2007
View article titled, MyD88- and Bruton’s Tyrosine Kinase-Mediated Signals Are Essential for T Cell-Independent Pathogen-Specific IgM Responses
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Journal Articles

TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat

Danny Zipris, Egil Lien, Anjali Nair, Jenny X. Xie, Dale L. Greiner, John P. Mordes, Aldo A. Rossini
Journal: The Journal of Immunology
J Immunol (2007) 178 (2): 693–701.
https://doi.org/10.4049/jimmunol.178.2.693
Published: 15 January 2007
View article titled, TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat
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Journal Articles

A Mechanism for Neurodegeneration Induced by Group B Streptococci through Activation of the TLR2/MyD88 Pathway in Microglia

Seija Lehnardt, Philipp Henneke, Egil Lien, Dennis L. Kasper, Joseph J. Volpe, Ingo Bechmann, Robert Nitsch, Joerg R. Weber, Douglas T. Golenbock, Timothy Vartanian
Journal: The Journal of Immunology
J Immunol (2006) 177 (1): 583–592.
https://doi.org/10.4049/jimmunol.177.1.583
Published: 01 July 2006
View article titled, A Mechanism for Neurodegeneration Induced by Group B Streptococci through Activation of the TLR2/MyD88 Pathway in Microglia
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Journal Articles

TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats

Danny Zipris, Egil Lien, Jenny X. Xie, Dale L. Greiner, John P. Mordes, Aldo A. Rossini
Journal: The Journal of Immunology
J Immunol (2005) 174 (1): 131–142.
https://doi.org/10.4049/jimmunol.174.1.131
Published: 01 January 2005
View article titled, TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats
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Journal Articles

Injury Primes the Innate Immune System for Enhanced Toll-Like Receptor Reactivity

Hugh M. Paterson, Thomas J. Murphy, Elizabeth J. Purcell, Odhran Shelley, Sara J. Kriynovich, Egil Lien, John A. Mannick, James A. Lederer
Journal: The Journal of Immunology
J Immunol (2003) 171 (3): 1473–1483.
https://doi.org/10.4049/jimmunol.171.3.1473
Published: 01 August 2003
View article titled, Injury Primes the Innate Immune System for Enhanced Toll-Like Receptor Reactivity
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Journal Articles

Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways

Philipp Henneke, Osamu Takeuchi, Richard Malley, Egil Lien, Robin R. Ingalls, Mason W. Freeman, Tanya Mayadas, Victor Nizet, Shizuo Akira, Dennis L. Kasper, Douglas T. Golenbock
Journal: The Journal of Immunology
J Immunol (2002) 169 (7): 3970–3977.
https://doi.org/10.4049/jimmunol.169.7.3970
Published: 01 October 2002
View article titled, Cellular Activation, Phagocytosis, and Bactericidal Activity Against Group B Streptococcus Involve Parallel Myeloid Differentiation Factor 88-Dependent and Independent Signaling Pathways
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Journal Articles

Response to Neisseria gonorrhoeae by Cervicovaginal Epithelial Cells Occurs in the Absence of Toll-Like Receptor 4-Mediated Signaling

Raina N. Fichorova, Amanda O. Cronin, Egil Lien, Deborah J. Anderson, Robin R. Ingalls
Journal: The Journal of Immunology
J Immunol (2002) 168 (5): 2424–2432.
https://doi.org/10.4049/jimmunol.168.5.2424
Published: 01 March 2002
View article titled, Response to <em>Neisseria gonorrhoeae</em> by Cervicovaginal Epithelial Cells Occurs in the Absence of Toll-Like Receptor 4-Mediated Signaling
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Induction of Tolerance to Lipopolysaccharide and Mycobacterial Components in Chinese Hamster Ovary/CD14 Cells Is Not Affected by Overexpression of Toll-Like Receptors 2 or 4

Andrei E. Medvedev, Philipp Henneke, Andra Schromm, Egil Lien, Robin Ingalls, Matthew J. Fenton, Douglas T. Golenbock, Stefanie N. Vogel
Journal: The Journal of Immunology
J Immunol (2001) 167 (4): 2257–2267.
https://doi.org/10.4049/jimmunol.167.4.2257
Published: 15 August 2001
View article titled, Induction of Tolerance to Lipopolysaccharide and Mycobacterial Components in Chinese Hamster Ovary/CD14 Cells Is Not Affected by Overexpression of Toll-Like Receptors 2 or 4
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Journal Articles

Human Toll-Like Receptor 2 Mediates Monocyte Activation by Listeria monocytogenes, But Not by Group B Streptococci or Lipopolysaccharide

Trude H. Flo, Øyvind Halaas, Egil Lien, Liv Ryan, Giuseppe Teti, Douglas T. Golenbock, Anders Sundan, Terje Espevik
Journal: The Journal of Immunology
J Immunol (2000) 164 (4): 2064–2069.
https://doi.org/10.4049/jimmunol.164.4.2064
Published: 15 February 2000
View article titled, Human Toll-Like Receptor 2 Mediates Monocyte Activation by <em>Listeria monocytogenes</em>, But Not by Group B Streptococci or Lipopolysaccharide
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The CD14 Ligands Lipoarabinomannan and Lipopolysaccharide Differ in Their Requirement for Toll-Like Receptors

Terry K. Means, Egil Lien, Atsutoshi Yoshimura, Shuyan Wang, Douglas T. Golenbock, Matthew J. Fenton
Journal: The Journal of Immunology
J Immunol (1999) 163 (12): 6748–6755.
https://doi.org/10.4049/jimmunol.163.12.6748
Published: 15 December 1999
View article titled, The CD14 Ligands Lipoarabinomannan and Lipopolysaccharide Differ in Their Requirement for Toll-Like Receptors
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Journal Articles

Human Toll-Like Receptors Mediate Cellular Activation by Mycobacterium tuberculosis

Terry K. Means, Shuyan Wang, Egil Lien, Atsutoshi Yoshimura, Douglas T. Golenbock, Matthew J. Fenton
Journal: The Journal of Immunology
J Immunol (1999) 163 (7): 3920–3927.
https://doi.org/10.4049/jimmunol.163.7.3920
Published: 01 October 1999
View article titled, Human Toll-Like Receptors Mediate Cellular Activation by <em>Mycobacterium tuberculosis</em>
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Activation of Human Monocytic Cells by Borrelia burgdorferi and Treponema pallidum Is Facilitated by CD14 and Correlates with Surface Exposure of Spirochetal Lipoproteins

Timothy J. Sellati, Deborah A. Bouis, Melissa J. Caimano, J. Amelia Feulner, Christopher Ayers, Egil Lien, Justin D. Radolf
Journal: The Journal of Immunology
J Immunol (1999) 163 (4): 2049–2056.
https://doi.org/10.4049/jimmunol.163.4.2049
Published: 15 August 1999
View article titled, Activation of Human Monocytic Cells by <em>Borrelia burgdorferi</em> and <em>Treponema pallidum</em> Is Facilitated by CD14 and Correlates with Surface Exposure of Spirochetal Lipoproteins
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Cutting Edge: Recognition of Gram-Positive Bacterial Cell Wall Components by the Innate Immune System Occurs Via Toll-Like Receptor 2

Atsutoshi Yoshimura, Egil Lien, Robin R. Ingalls, Elaine Tuomanen, Roman Dziarski, Douglas Golenbock
Journal: The Journal of Immunology
J Immunol (1999) 163 (1): 1–5.
https://doi.org/10.4049/jimmunol.163.1.1
Published: 01 July 1999
View article titled, Cutting Edge: Recognition of Gram-Positive Bacterial Cell Wall Components by the Innate Immune System Occurs Via Toll-Like Receptor 2
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Cutting Edge: Cells That Carry A Null Allele for Toll-Like Receptor 2 Are Capable of Responding to Endotoxin

Holger Heine, Carsten J. Kirschning, Egil Lien, Brian G. Monks, Mike Rothe, Douglas T. Golenbock
Journal: The Journal of Immunology
J Immunol (1999) 162 (12): 6971–6975.
https://doi.org/10.4049/jimmunol.162.12.6971
Published: 15 June 1999
View article titled, Cutting Edge: Cells That Carry A Null Allele for Toll-Like Receptor 2 Are Capable of Responding to Endotoxin
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