1-18 of 18
Emma Gostick
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8+ T Cells in Elderly Humans

Francesco Nicoli, Mariela P. Cabral-Piccin, Laura Papagno, Eleonora Gallerani, Mathieu Fusaro, Victor Folcher, Marion Dubois, Emmanuel Clave, Hélène Vallet, Justin J. Frere, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Antoine Toubert, Loïc Dupré, Jacques Boddaert, Antonella Caputo, Riccardo Gavioli, Victor Appay
Journal: The Journal of Immunology
J Immunol (2022) 208 (3): 562–570.
https://doi.org/10.4049/jimmunol.2100194
Published: 01 February 2022
View article titled, Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8<sup>+</sup> T Cells in Elderly Humans
Open the PDF for Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8<sup>+</sup> T Cells in Elderly Humans in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus

Corinne J. Smith, Vanessa Venturi, Maire F. Quigley, Holly Turula, Emma Gostick, Kristin Ladell, Brenna J. Hill, Danielle Himelfarb, Kylie M. Quinn, Hui Yee Greenaway, Thurston H. Y. Dang, Robert A. Seder, Daniel C. Douek, Ann B. Hill, Miles P. Davenport, David A. Price, Christopher M. Snyder
Journal: The Journal of Immunology
J Immunol (2020) 204 (1): 112–121.
https://doi.org/10.4049/jimmunol.1900455
Published: 01 January 2020
View article titled, Stochastic Expansions Maintain the Clonal Stability of CD8<sup>+</sup> T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus
Open the PDF for Stochastic Expansions Maintain the Clonal Stability of CD8<sup>+</sup> T Cell Populations Undergoing Memory Inflation Driven by Murine Cytomegalovirus in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

James E. McLaren, Mathew Clement, Morgan Marsden, Kelly L. Miners, Sian Llewellyn-Lacey, Emma J. Grant, Anzelika Rubina, Silvia Gimeno Brias, Emma Gostick, Maria A. Stacey, Selinda J. Orr, Richard J. Stanton, Kristin Ladell, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 943–955.
https://doi.org/10.4049/jimmunol.1701757
Published: 01 February 2019
View article titled, IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
Open the PDF for IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses

Alice Gutjahr, Laura Papagno, Francesco Nicoli, Alain Lamoureux, Fabienne Vernejoul, Thierry Lioux, Emma Gostick, David A. Price, Gérard Tiraby, Eric Perouzel, Victor Appay, Bernard Verrier, Stéphane Paul
Journal: The Journal of Immunology
J Immunol (2017) 198 (11): 4205–4209.
https://doi.org/10.4049/jimmunol.1602131
Published: 01 June 2017
View article titled, Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses
Open the PDF for Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation

Linda Wooldridge, David Morgan, James Alexander Pearson, Stephanie Gras, Hugo van den Berg, Anya Lissina, Sian Llewellyn-Lacey, Mark Willis, Tamsin Dockree, James E McLaren, Julia Ekeruche-Makinde, Emma Gostick, Neil Robertson, Jamie Rossjohn, Scott R Burrows, David Price, Susan Wong, Mark Peakman, Ania Skowera, Matthew Clement
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 127.26.
https://doi.org/10.4049/jimmunol.198.Supp.127.26
Published: 01 May 2017
View article titled, Autoreactive CD8<sup>+</sup> T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8<sup>+</sup> T-cell activation
Add to Citation Manager
Journal Articles

Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand

Anna Lissina, Olivia Briceño, Georgia Afonso, Martin Larsen, Emma Gostick, David A. Price, Roberto Mallone, Victor Appay
Journal: The Journal of Immunology
J Immunol (2016) 196 (1): 256–263.
https://doi.org/10.4049/jimmunol.1501140
Published: 01 January 2016
View article titled, Priming of Qualitatively Superior Human Effector CD8<sup>+</sup> T Cells Using TLR8 Ligand Combined with FLT3 Ligand
Open the PDF for Priming of Qualitatively Superior Human Effector CD8<sup>+</sup> T Cells Using TLR8 Ligand Combined with FLT3 Ligand in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations

Brenna J. Hill, Patricia A. Darrah, Zachary Ende, David R. Ambrozak, Kylie M. Quinn, Sam Darko, Emma Gostick, Linda Wooldridge, Hugo A. van den Berg, Vanessa Venturi, Martin Larsen, Miles P. Davenport, Robert A. Seder, David A. Price, Daniel C. Douek
Journal: The Journal of Immunology
J Immunol (2014) 193 (11): 5626–5636.
https://doi.org/10.4049/jimmunol.1401017
Published: 01 December 2014
View article titled, Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations
Open the PDF for Epitope Specificity Delimits the Functional Capabilities of Vaccine-Induced CD8 T Cell Populations in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity

Geraldine M. O’Connor, Julian P. Vivian, Jacqueline M. Widjaja, John S. Bridgeman, Emma Gostick, Bernard A. P. Lafont, Stephen K. Anderson, David A. Price, Andrew G. Brooks, Jamie Rossjohn, Daniel W. McVicar
Journal: The Journal of Immunology
J Immunol (2014) 192 (6): 2875–2884.
https://doi.org/10.4049/jimmunol.1303142
Published: 15 March 2014
View article titled, Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity
Open the PDF for Mutational and Structural Analysis of KIR3DL1 Reveals a Lineage-Defining Allotypic Dimorphism That Impacts Both HLA and Peptide Sensitivity in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8+ T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization

Kylie M. Quinn, Andreia Da Costa, Ayako Yamamoto, Dana Berry, Ross W. B. Lindsay, Patricia A. Darrah, Lingshu Wang, Cheng Cheng, Wing-Pui Kong, Jason G. D. Gall, Alfredo Nicosia, Antonella Folgori, Stefano Colloca, Riccardo Cortese, Emma Gostick, David A. Price, Carmen E. Gomez, Mariano Esteban, Linda S. Wyatt, Bernard Moss, Cecilia Morgan, Mario Roederer, Robert T. Bailer, Gary J. Nabel, Richard A. Koup, Robert A. Seder
Journal: The Journal of Immunology
J Immunol (2013) 190 (6): 2720–2735.
https://doi.org/10.4049/jimmunol.1202861
Published: 15 March 2013
View article titled, Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8<sup>+</sup> T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization
Open the PDF for Comparative Analysis of the Magnitude, Quality, Phenotype, and Protective Capacity of Simian Immunodeficiency Virus Gag-Specific CD8<sup>+</sup> T Cells following Human-, Simian-, and Chimpanzee-Derived Recombinant Adenoviral Vector Immunization in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Degenerate Recognition of MHC Class I Molecules with Bw4 and Bw6 Motifs by a Killer Cell Ig-like Receptor 3DL Expressed by Macaque NK Cells

Sebastien M. Maloveste, Dan Chen, Emma Gostick, Julian P. Vivian, Ronald J. Plishka, Ranjini Iyengar, Robin L. Kruthers, Alicia Buckler-White, Andrew G. Brooks, Jamie Rossjohn, David A. Price, Bernard A. P. Lafont
Journal: The Journal of Immunology
J Immunol (2012) 189 (9): 4338–4348.
https://doi.org/10.4049/jimmunol.1201360
Published: 01 November 2012
View article titled, Degenerate Recognition of MHC Class I Molecules with Bw4 and Bw6 Motifs by a Killer Cell Ig-like Receptor 3DL Expressed by Macaque NK Cells
Open the PDF for Degenerate Recognition of MHC Class I Molecules with Bw4 and Bw6 Motifs by a Killer Cell Ig-like Receptor 3DL Expressed by Macaque NK Cells in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity

Matthew J. Johnson, Constantinos Petrovas, Takuya Yamamoto, Ross W. B. Lindsay, Karin Loré, Jason G. D. Gall, Emma Gostick, François Lefebvre, Mark J. Cameron, David A. Price, Elias Haddad, Rafick-Pierre Sekaly, Robert A. Seder, Richard A. Koup
Journal: The Journal of Immunology
J Immunol (2012) 188 (12): 6109–6118.
https://doi.org/10.4049/jimmunol.1103717
Published: 15 June 2012
View article titled, Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity
Open the PDF for Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Structural Basis of Diverse Peptide Accommodation by the Rhesus Macaque MHC Class I Molecule Mamu-B*17: Insights into Immune Protection from Simian Immunodeficiency Virus

Yan Wu, Feng Gao, Jun Liu, Jianxun Qi, Emma Gostick, David A. Price, George F. Gao
Journal: The Journal of Immunology
J Immunol (2011) 187 (12): 6382–6392.
https://doi.org/10.4049/jimmunol.1101726
Published: 15 December 2011
View article titled, Structural Basis of Diverse Peptide Accommodation by the Rhesus Macaque MHC Class I Molecule Mamu-B*17: Insights into Immune Protection from Simian Immunodeficiency Virus
Open the PDF for Structural Basis of Diverse Peptide Accommodation by the Rhesus Macaque MHC Class I Molecule Mamu-B*17: Insights into Immune Protection from Simian Immunodeficiency Virus in another window
Add to Citation Manager
Journal Articles

Allogeneic HLA-A*02–Restricted WT1-Specific T Cells from Mismatched Donors Are Highly Reactive but Show Off-Target Promiscuity

Willem J. J. Falkenburg, J. Joseph Melenhorst, Marian van de Meent, Michel G. D. Kester, Pleun Hombrink, Mirjam H. M. Heemskerk, Renate S. Hagedoorn, Emma Gostick, David A. Price, J. H. Frederik Falkenburg, A. John Barrett, Inge Jedema
Journal: The Journal of Immunology
J Immunol (2011) 187 (5): 2824–2833.
https://doi.org/10.4049/jimmunol.1100852
Published: 01 September 2011
View article titled, Allogeneic HLA-A*02–Restricted WT1-Specific T Cells from Mismatched Donors Are Highly Reactive but Show Off-Target Promiscuity
Open the PDF for Allogeneic HLA-A*02–Restricted WT1-Specific T Cells from Mismatched Donors Are Highly Reactive but Show Off-Target Promiscuity in another window
Add to Citation Manager
Journal Articles

IL-10 Restricts Memory T Cell Inflation during Cytomegalovirus Infection

Morgan Jones, Kristin Ladell, Katherine K. Wynn, Maria A. Stacey, Máire F. Quigley, Emma Gostick, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2010) 185 (6): 3583–3592.
https://doi.org/10.4049/jimmunol.1001535
Published: 15 September 2010
View article titled, IL-10 Restricts Memory T Cell Inflation during Cytomegalovirus Infection
Open the PDF for IL-10 Restricts Memory T Cell Inflation during Cytomegalovirus Infection in another window
Add to Citation Manager
Includes: Supplementary data
Journal Articles

Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

David K. Cole, Emily S. J. Edwards, Katherine K. Wynn, Mathew Clement, John J. Miles, Kristin Ladell, Julia Ekeruche, Emma Gostick, Katherine J. Adams, Ania Skowera, Mark Peakman, Linda Wooldridge, David A. Price, Andrew K. Sewell
Journal: The Journal of Immunology
J Immunol (2010) 185 (4): 2600–2610.
https://doi.org/10.4049/jimmunol.1000629
Published: 15 August 2010
View article titled, Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition
Open the PDF for Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition in another window
Add to Citation Manager
Journal Articles

MHC Class I Molecules with Superenhanced CD8 Binding Properties Bypass the Requirement for Cognate TCR Recognition and Nonspecifically Activate CTLs

Linda Wooldridge, Mathew Clement, Anna Lissina, Emily S. J. Edwards, Kristin Ladell, Julia Ekeruche, Rachel E. Hewitt, Bruno Laugel, Emma Gostick, David K. Cole, Reno Debets, Cor Berrevoets, John J. Miles, Scott R. Burrows, David A. Price, Andrew K. Sewell
Journal: The Journal of Immunology
J Immunol (2010) 184 (7): 3357–3366.
https://doi.org/10.4049/jimmunol.0902398
Published: 01 April 2010
View article titled, MHC Class I Molecules with Superenhanced CD8 Binding Properties Bypass the Requirement for Cognate TCR Recognition and Nonspecifically Activate CTLs
Open the PDF for MHC Class I Molecules with Superenhanced CD8 Binding Properties Bypass the Requirement for Cognate TCR Recognition and Nonspecifically Activate CTLs in another window
Add to Citation Manager
Journal Articles

Availability of a Diversely Avid CD8+ T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p2419–27 Epitope

Keri L. Schaubert, David A. Price, Nicole Frahm, Jinzhu Li, Hwee L. Ng, Aviva Joseph, Elyse Paul, Biswanath Majumder, Velpandi Ayyavoo, Emma Gostick, Sharon Adams, Francesco M. Marincola, Andrew K. Sewell, Marcus Altfeld, Jason M. Brenchley, Daniel C. Douek, Otto O. Yang, Christian Brander, Harris Goldstein, June Kan-Mitchell
Journal: The Journal of Immunology
J Immunol (2007) 178 (12): 7756–7766.
https://doi.org/10.4049/jimmunol.178.12.7756
Published: 15 June 2007
View article titled, Availability of a Diversely Avid CD8<sup>+</sup> T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p24<sub>19–27</sub> Epitope
Open the PDF for Availability of a Diversely Avid CD8<sup>+</sup> T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p24<sub>19–27</sub> Epitope in another window
Add to Citation Manager
Journal Articles

Human TCR-Binding Affinity is Governed by MHC Class Restriction

David K. Cole, Nicholas J. Pumphrey, Jonathan M. Boulter, Malkit Sami, John I. Bell, Emma Gostick, David A. Price, George F. Gao, Andrew K. Sewell, Bent K. Jakobsen
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5727–5734.
https://doi.org/10.4049/jimmunol.178.9.5727
Published: 01 May 2007
View article titled, Human TCR-Binding Affinity is Governed by MHC Class Restriction
Open the PDF for Human TCR-Binding Affinity is Governed by MHC Class Restriction in another window
Add to Citation Manager