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Emmanuel J. H. J. Wiertz
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Journal Articles

EBV MicroRNA BART16 Suppresses Type I IFN Signaling

Marjolein J. G. Hooykaas, Michiel van Gent, Jasper A. Soppe, Elisabeth Kruse, Ingrid G. J. Boer, Dik van Leenen, Marian J. A. Groot Koerkamp, Frank C. P. Holstege, Maaike E. Ressing, Emmanuel J. H. J. Wiertz, Robert Jan Lebbink
Journal: The Journal of Immunology
J Immunol (2017) 198 (10): 4062–4073.
https://doi.org/10.4049/jimmunol.1501605
Published: 15 May 2017
View article titled, EBV MicroRNA BART16 Suppresses Type I IFN Signaling
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Includes: Supplementary data
Journal Articles

Cowpox Virus Protein CPXV012 Eludes CTLs by Blocking ATP Binding to TAP

Rutger D. Luteijn, Hanneke Hoelen, Elisabeth Kruse, Wouter F. van Leeuwen, Jennine Grootens, Daniëlle Horst, Martijn Koorengevel, Jan W. Drijfhout, Elisabeth Kremmer, Klaus Früh, Jacques J. Neefjes, Antoinette Killian, Robert Jan Lebbink, Maaike E. Ressing, Emmanuel J. H. J. Wiertz
Journal: The Journal of Immunology
J Immunol (2014) 193 (4): 1578–1589.
https://doi.org/10.4049/jimmunol.1400964
Published: 15 August 2014
View article titled, Cowpox Virus Protein CPXV012 Eludes CTLs by Blocking ATP Binding to TAP
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Journal Articles

EBV Protein BNLF2a Exploits Host Tail-Anchored Protein Integration Machinery To Inhibit TAP

Daniëlle Horst, Vincenzo Favaloro, Fabio Vilardi, Hans C. van Leeuwen, Malgorzata A. Garstka, Andrew D. Hislop, Catherine Rabu, Elisabeth Kremmer, Alan B. Rickinson, Stephen High, Bernhard Dobberstein, Maaike E. Ressing, Emmanuel J. H. J. Wiertz
Journal: The Journal of Immunology
J Immunol (2011) 186 (6): 3594–3605.
https://doi.org/10.4049/jimmunol.1002656
Published: 15 March 2011
View article titled, EBV Protein BNLF2a Exploits Host Tail-Anchored Protein Integration Machinery To Inhibit TAP
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Includes: Supplementary data
Journal Articles

Noncytotoxic Inhibition of Cytomegalovirus Replication through NK Cell Protease Granzyme M-Mediated Cleavage of Viral Phosphoprotein 71

Robert van Domselaar, Leonne E. Philippen, Razi Quadir, Emmanuel J. H. J. Wiertz, J. Alain Kummer, Niels Bovenschen
Journal: The Journal of Immunology
J Immunol (2010) 185 (12): 7605–7613.
https://doi.org/10.4049/jimmunol.1001503
Published: 15 December 2010
View article titled, Noncytotoxic Inhibition of Cytomegalovirus Replication through NK Cell Protease Granzyme M-Mediated Cleavage of Viral Phosphoprotein 71
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Journal Articles

CD8+ T Cell Responses against TAP-Inhibited Cells Are Readily Detected in the Human Population

Margit H. Lampen, Marieke C. Verweij, Bianca Querido, Sjoerd H. van der Burg, Emmanuel J. H. J. Wiertz, Thorbald van Hall
Journal: The Journal of Immunology
J Immunol (2010) 185 (11): 6508–6517.
https://doi.org/10.4049/jimmunol.1001774
Published: 01 December 2010
View article titled, CD8<sup>+</sup> T Cell Responses against TAP-Inhibited Cells Are Readily Detected in the Human Population
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Includes: Supplementary data
Journal Articles

Specific Targeting of the EBV Lytic Phase Protein BNLF2a to the Transporter Associated with Antigen Processing Results in Impairment of HLA Class I-Restricted Antigen Presentation

Daniëlle Horst, Daphne van Leeuwen, Nathan P. Croft, Malgorzata A. Garstka, Andrew D. Hislop, Elisabeth Kremmer, Alan B. Rickinson, Emmanuel J. H. J. Wiertz, Maaike E. Ressing
Journal: The Journal of Immunology
J Immunol (2009) 182 (4): 2313–2324.
https://doi.org/10.4049/jimmunol.0803218
Published: 15 February 2009
View article titled, Specific Targeting of the EBV Lytic Phase Protein BNLF2a to the Transporter Associated with Antigen Processing Results in Impairment of HLA Class I-Restricted Antigen Presentation
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Journal Articles

The Varicellovirus UL49.5 Protein Blocks the Transporter Associated with Antigen Processing (TAP) by Inhibiting Essential Conformational Transitions in the 6+6 Transmembrane TAP Core Complex

Marieke C. Verweij, Danijela Koppers-Lalic, Sandra Loch, Florian Klauschies, Henri de la Salle, Edwin Quinten, Paul J. Lehner, Arend Mulder, Michael R. Knittler, Robert Tampé, Joachim Koch, Maaike E. Ressing, Emmanuel J. H. J. Wiertz
Journal: The Journal of Immunology
J Immunol (2008) 181 (7): 4894–4907.
https://doi.org/10.4049/jimmunol.181.7.4894
Published: 01 October 2008
View article titled, The Varicellovirus UL49.5 Protein Blocks the Transporter Associated with Antigen Processing (TAP) by Inhibiting Essential Conformational Transitions in the 6+6 Transmembrane TAP Core Complex
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Journal Articles

Viral immune evasion protein mK3 targets MHC I proteins for rapid degradation by specifically ubiquitinating serine or lysine residues in the cytoplasmic tail of the heavy chain (45.9)

Roger Alan Herr, Lonnie Lybarger, Emmanuel J. H. J. Wiertz, Xiaoli Wang, Ted H. Hansen
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S58–S59.
https://doi.org/10.4049/jimmunol.178.Supp.45.9
Published: 01 April 2007
View article titled, Viral immune evasion protein mK3 targets MHC I proteins for rapid degradation by specifically ubiquitinating serine or lysine residues in the cytoplasmic tail of the heavy chain (45.9)
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Journal Articles

The Varicellovirus-Encoded TAP Inhibitor UL49.5 Regulates the Presentation of CTL Epitopes by Qa-1b1

Thorbald van Hall, Sandra Laban, Danijela Koppers-Lalic, Joachim Koch, Calin Precup, Patrick Asmawidjaja, Rienk Offringa, Emmanuel J. H. J. Wiertz
Journal: The Journal of Immunology
J Immunol (2007) 178 (2): 657–662.
https://doi.org/10.4049/jimmunol.178.2.657
Published: 15 January 2007
View article titled, The Varicellovirus-Encoded TAP Inhibitor UL49.5 Regulates the Presentation of CTL Epitopes by Qa-1<sup>b1</sup>
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Journal Articles

Impaired Transporter Associated with Antigen Processing-Dependent Peptide Transport during Productive EBV Infection

Maaike E. Ressing, Sinéad E. Keating, Daphne van Leeuwen, Danijela Koppers-Lalic, Isabel Y. Pappworth, Emmanuel J. H. J. Wiertz, Martin Rowe
Journal: The Journal of Immunology
J Immunol (2005) 174 (11): 6829–6838.
https://doi.org/10.4049/jimmunol.174.11.6829
Published: 01 June 2005
View article titled, Impaired Transporter Associated with Antigen Processing-Dependent Peptide Transport during Productive EBV Infection
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Journal Articles

Human Cytomegalovirus-Encoded US2 Differentially Affects Surface Expression of MHC Class I Locus Products and Targets Membrane-Bound, but Not Soluble HLA-G1 for Degradation

Martine T. Barel, Maaike Ressing, Nathalie Pizzato, Daphne van Leeuwen, Philippe Le Bouteiller, Francoise Lenfant, Emmanuel J. H. J. Wiertz
Journal: The Journal of Immunology
J Immunol (2003) 171 (12): 6757–6765.
https://doi.org/10.4049/jimmunol.171.12.6757
Published: 15 December 2003
View article titled, Human Cytomegalovirus-Encoded US2 Differentially Affects Surface Expression of MHC Class I Locus Products and Targets Membrane-Bound, but Not Soluble HLA-G1 for Degradation
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