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An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes

Sabrina Helmold Hait, Christopher James Hogge, Mohammad Arif Rahman, Eun-Ju Ko, Ruth Hunegnaw, Zuena Mushtaq, Gospel Enyindah-Asonye, Tanya Hoang, Lisa M. Miller Jenkins, Ettore Appella, Daniel H. Appella, Marjorie Robert-Guroff

J Immunol (2020) 204 (12): 3315–3328.

DOI: https://doi.org/10.4049/jimmunol.2000165

Published: 15 June 2020

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The p53 Saga: Early Steps in the Development of Tumor Immunotherapy

In Special Collection:

Brief Reviews

Albert B. DeLeo, Ettore Appella

J Immunol (2020) 204 (9): 2321–2328.

DOI: https://doi.org/10.4049/jimmunol.1901343

Published: 01 May 2020

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Pillars Article: Purification of a Human Monocyte-Derived Neutrophil Chemotactic Factor That Has Peptide Sequence Similarity to Other Host Defense Cytokines. Proc. Natl. Acad. Sci. USA 1987. 84: 9233–9237

Teizo Yoshimura, Kouji Matsushima, Shuji Tanaka, Elizabeth A. Robinson, Ettore Appella, Joost J. Oppenheim, Edward J. Leonard

J Immunol (2019) 202 (1): 5–9.

Published: 01 January 2019

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Studying the cooperativity at the SLP-76 signaling complex critical for the immune response (50.7)

Mira Barda-Saad, Naoto Shirasu, Maor Pauker, Nirit Hasan, Orly Perl, Andrea Balbo, Hiroshi Yamaguchi, Jon Houtman, Ettore Appella, Peter Schuck, Lawrence Samelson

J Immunol (2010) 184 (1_Supplement): 50.7.

DOI: https://doi.org/10.4049/jimmunol.184.Supp.50.7

Published: 01 April 2010

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Pillars Article: Characterization of Peptides Bound to the Class I MHC Molecule HLA-A2.1 by Mass Spectrometry. Science 1992. 255: 1261–1263.

Donald F. Hunt, Robert A. Henderson, Jeffrey Shabanowitz, Kazuyasu Sakaguchi, Hanspeter Michel, Noelle Sevilir, Andrea L. Cox, Ettore Appella, Victor H. Engelhard

J Immunol (2007) 179 (5): 2669–2671.

Published: 01 September 2007

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The Wild-Type Sequence (wt) p53_25–35 Peptide Induces HLA-DR7 and HLA-DR11-Restricted CD4⁺ Th Cells Capable of Enhancing the Ex Vivo Expansion and Function of Anti-wt p53_264–272 Peptide CD8⁺ T Cells

Daisuke Ito, Andreas Albers, Yong Xiang Zhao, Carmen Visus, Ettore Appella, Theresa L. Whiteside, Albert B. DeLeo

J Immunol (2006) 177 (10): 6795–6803.

DOI: https://doi.org/10.4049/jimmunol.177.10.6795

Published: 15 November 2006

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Wip1 Phosphatase-Deficient Mice Exhibit Defective T Cell Maturation Due To Sustained p53 Activation

Marco L. Schito, Oleg N. Demidov, Shin’ichi Saito, Jonathan D. Ashwell, Ettore Appella

J Immunol (2006) 176 (8): 4818–4825.

DOI: https://doi.org/10.4049/jimmunol.176.8.4818

Published: 15 April 2006

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A CD8⁺ T Cell Heptaepitope Minigene Vaccine Induces Protective Immunity against Chlamydia pneumoniae

Irina Pinchuk, Barry C. Starcher, Brian Livingston, Amy Tvninnereim, Shiping Wu, Ettore Appella, John Sidney, Alessandro Sette, Benjamin Wizel

J Immunol (2005) 174 (9): 5729–5739.

DOI: https://doi.org/10.4049/jimmunol.174.9.5729

Published: 01 May 2005

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Multiepitope Trojan Antigen Peptide Vaccines for the Induction of Antitumor CTL and Th Immune Responses

Jun Lu, Yuichiro Higashimoto, Ettore Appella, Esteban Celis

J Immunol (2004) 172 (7): 4575–4582.

DOI: https://doi.org/10.4049/jimmunol.172.7.4575

Published: 01 April 2004

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High Affinity Xenoreactive TCR:MHC Interaction Recruits CD8 in Absence of Binding to MHC

Jennifer Buslepp, Samantha E. Kerry, Doug Loftus, Jeffrey A. Frelinger, Ettore Appella, Edward J. Collins

J Immunol (2003) 170 (1): 373–383.

DOI: https://doi.org/10.4049/jimmunol.170.1.373

Published: 01 January 2003

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Multiple Chlamydia pneumoniae Antigens Prime CD8⁺ Tc1 Responses That Inhibit Intracellular Growth of This Vacuolar Pathogen

Benjamin Wizel, Barry C. Starcher, Buka Samten, Zissis Chroneos, Peter F. Barnes, John Dzuris, Yuichiro Higashimoto, Ettore Appella, Alessandro Sette

J Immunol (2002) 169 (5): 2524–2535.

DOI: https://doi.org/10.4049/jimmunol.169.5.2524

Published: 01 September 2002

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A Decaepitope Polypeptide Primes for Multiple CD8⁺ IFN-γ and Th Lymphocyte Responses: Evaluation of Multiepitope Polypeptides as a Mode for Vaccine Delivery

Jeff Alexander, Carla Oseroff, Carol Dahlberg, Mingsheng Qin, Glenn Ishioka, Melanie Beebe, John Fikes, Mark Newman, Robert W. Chesnut, Phillip A. Morton, Kam Fok, Ettore Appella, Alessandro Sette

J Immunol (2002) 168 (12): 6189–6198.

DOI: https://doi.org/10.4049/jimmunol.168.12.6189

Published: 15 June 2002

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A Rational Strategy to Design Multiepitope Immunogens Based on Multiple Th Lymphocyte Epitopes

Brian Livingston, Claire Crimi, Mark Newman, Yuichiro Higashimoto, Ettore Appella, John Sidney, Alessandro Sette

J Immunol (2002) 168 (11): 5499–5506.

DOI: https://doi.org/10.4049/jimmunol.168.11.5499

Published: 01 June 2002

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The Ability of Variant Peptides to Reverse the Nonresponsiveness of T Lymphocytes to the Wild-Type Sequence p53_264–272 Epitope

Thomas K. Hoffmann, Douglas J. Loftus, Koji Nakano, Markus J. Maeurer, Kazuaki Chikamatsu, Ettore Appella, Theresa L. Whiteside, Albert B. DeLeo

J Immunol (2002) 168 (3): 1338–1347.

DOI: https://doi.org/10.4049/jimmunol.168.3.1338

Published: 01 February 2002

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TAP-Independent Presentation of CTL Epitopes by Trojan Antigens

Jun Lu, Peter J. Wettstein, Yuichiro Higashimoto, Ettore Appella, Esteban Celis

J Immunol (2001) 166 (12): 7063–7071.

DOI: https://doi.org/10.4049/jimmunol.166.12.7063

Published: 15 June 2001

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Definition of the Mamu A*01 Peptide Binding Specificity: Application to the Identification of Wild-Type and Optimized Ligands from Simian Immunodeficiency Virus Regulatory Proteins

John Sidney, John L. Dzuris, Mark J. Newman, R. Paul Johnson, Kaur Amitinder, Christopher M. Walker, Ettore Appella, Bianca Mothe, David I. Watkins, Alessandro Sette

J Immunol (2000) 165 (11): 6387–6399.

DOI: https://doi.org/10.4049/jimmunol.165.11.6387

Published: 01 December 2000

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Generation of T Cells Specific for the Wild-Type Sequence p53_264–272 Peptide in Cancer Patients: Implications for Immunoselection of Epitope Loss Variants

Thomas K. Hoffmann, Koji Nakano, Elaine M. Elder, Grzegorz Dworacki, Sydney D. Finkelstein, Ettore Appella, Theresa L. Whiteside, Albert B. DeLeo

J Immunol (2000) 165 (10): 5938–5944.

DOI: https://doi.org/10.4049/jimmunol.165.10.5938

Published: 15 November 2000

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HLA-DR-Promiscuous T Cell Epitopes from Plasmodium falciparum Pre-Erythrocytic-Stage Antigens Restricted by Multiple HLA Class II Alleles

Denise L. Doolan, Scott Southwood, Robert Chesnut, Ettore Appella, Eduardo Gomez, Allen Richards, Yuichiro I. Higashimoto, Ajesh Maewal, John Sidney, Robert A. Gramzinski, Carl Mason, Davy Koech, Stephen L. Hoffman, Alessandro Sette

J Immunol (2000) 165 (2): 1123–1137.

DOI: https://doi.org/10.4049/jimmunol.165.2.1123

Published: 15 July 2000

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Conserved MHC Class I Peptide Binding Motif Between Humans and Rhesus Macaques

John L. Dzuris, John Sidney, Ettore Appella, Robert W. Chesnut, David I. Watkins, Alessandro Sette

J Immunol (2000) 164 (1): 283–291.

DOI: https://doi.org/10.4049/jimmunol.164.1.283

Published: 01 January 2000

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Identification of New HER2/neu-Derived Peptide Epitopes That Can Elicit Specific CTL Against Autologous and Allogeneic Carcinomas and Melanomas

Yang Rongcun, Flavio Salazar-Onfray, Jehad Charo, Karl-Johan Malmberg, Kristina Evrin, Hubert Maes, Koji Kono, Christina Hising, Max Petersson, Olle Larsson, Li Lan, Ettore Appella, Alessandro Sette, Esteban Celis3, Rolf Kiessling

J Immunol (1999) 163 (2): 1037–1044.

DOI: https://doi.org/10.4049/jimmunol.163.2.1037

Published: 15 July 1999

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NARROW

An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes

The p53 Saga: Early Steps in the Development of Tumor Immunotherapy

Pillars Article: Purification of a Human Monocyte-Derived Neutrophil Chemotactic Factor That Has Peptide Sequence Similarity to Other Host Defense Cytokines. Proc. Natl. Acad. Sci. USA 1987. 84: 9233–9237

Studying the cooperativity at the SLP-76 signaling complex critical for the immune response (50.7)

Pillars Article: Characterization of Peptides Bound to the Class I MHC Molecule HLA-A2.1 by Mass Spectrometry. Science 1992. 255: 1261–1263.

The Wild-Type Sequence (wt) p53_25–35 Peptide Induces HLA-DR7 and HLA-DR11-Restricted CD4⁺ Th Cells Capable of Enhancing the Ex Vivo Expansion and Function of Anti-wt p53_264–272 Peptide CD8⁺ T Cells

Wip1 Phosphatase-Deficient Mice Exhibit Defective T Cell Maturation Due To Sustained p53 Activation

A CD8⁺ T Cell Heptaepitope Minigene Vaccine Induces Protective Immunity against Chlamydia pneumoniae

Multiepitope Trojan Antigen Peptide Vaccines for the Induction of Antitumor CTL and Th Immune Responses

High Affinity Xenoreactive TCR:MHC Interaction Recruits CD8 in Absence of Binding to MHC

Multiple Chlamydia pneumoniae Antigens Prime CD8⁺ Tc1 Responses That Inhibit Intracellular Growth of This Vacuolar Pathogen

A Decaepitope Polypeptide Primes for Multiple CD8⁺ IFN-γ and Th Lymphocyte Responses: Evaluation of Multiepitope Polypeptides as a Mode for Vaccine Delivery

A Rational Strategy to Design Multiepitope Immunogens Based on Multiple Th Lymphocyte Epitopes

The Ability of Variant Peptides to Reverse the Nonresponsiveness of T Lymphocytes to the Wild-Type Sequence p53_264–272 Epitope

TAP-Independent Presentation of CTL Epitopes by Trojan Antigens

Definition of the Mamu A*01 Peptide Binding Specificity: Application to the Identification of Wild-Type and Optimized Ligands from Simian Immunodeficiency Virus Regulatory Proteins

Generation of T Cells Specific for the Wild-Type Sequence p53_264–272 Peptide in Cancer Patients: Implications for Immunoselection of Epitope Loss Variants

HLA-DR-Promiscuous T Cell Epitopes from Plasmodium falciparum Pre-Erythrocytic-Stage Antigens Restricted by Multiple HLA Class II Alleles

Conserved MHC Class I Peptide Binding Motif Between Humans and Rhesus Macaques

Identification of New HER2/neu-Derived Peptide Epitopes That Can Elicit Specific CTL Against Autologous and Allogeneic Carcinomas and Melanomas

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