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Genoveffa Franchini
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Journal Articles

Neutrophil Vaccination Dynamics and Their Capacity To Mediate B Cell Help in Rhesus Macaques

Thomas Musich, Mohammad Arif Rahman, Venkatramanan Mohanram, Leia Miller-Novak, Thorsten Demberg, David J. Venzon, Barbara K. Felber, Genoveffa Franchini, George N. Pavlakis, Marjorie Robert-Guroff
Journal: The Journal of Immunology
J Immunol (2018) 201 (8): 2287–2302.
DOI: https://doi.org/10.4049/jimmunol.1800677
Published: 15 October 2018
View article titled, Neutrophil Vaccination Dynamics and Their Capacity To Mediate B Cell Help in Rhesus Macaques
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Includes: Supplementary data
Journal Articles

Vaccine-induced temporal cross-talk between myeloid cells reduces the risk of SIVmac251 acquisition

Monica Vaccari, Shari N Gordon, Slim Fourati, Dallas Brown, Massimiliano Bissa, Melvin N Doster, Brandon K Keele, Luca Schifanella, N Lyianage, Kathryn Foulds, Mario Roederer, David Venzon, Barbara K. Felber, Margherita Rosati, George N Pavlakis, Dan H Barouch, Rafick P Sekaly, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 225.23.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.225.23
Published: 01 May 2017
View article titled, Vaccine-induced temporal cross-talk between myeloid cells reduces the risk of SIV<sub>mac251</sub> acquisition
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Modulation of DNA/ALVAC/gp120 vaccine immune-response by vaccination with Insulin-Like Growth Factor 1 (IGF-1)

Massimiliano Bissa, Veronica Galli, Luca Schifanella, Giacomo Gorini, Isabela Silva De Castro, Dallas Brown, Melvin N Doster, Namal Liyanage, Margherita Rosati, Barbara K. Felber, George N Pavlakis, Sanjay Phogat, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 225.17.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.225.17
Published: 01 May 2017
View article titled, Modulation of DNA/ALVAC/gp120 vaccine immune-response by vaccination with Insulin-Like Growth Factor 1 (IGF-1)
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Journal Articles

Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition

Shari N. Gordon, Namal P. M. Liyanage, Melvin N. Doster, Monica Vaccari, Diego A. Vargas-Inchaustegui, Poonam Pegu, Luca Schifanella, Xiaoying Shen, Georgia D. Tomaras, Mangala Rao, Erik A. Billings, Jennifer Schwartz, Ilia Prado, Kathryn Bobb, Wenlei Zhang, David C. Montefiori, Kathryn E. Foulds, Guido Ferrari, Marjorie Robert-Guroff, Mario Roederer, Tran B. Phan, Donald N. Forthal, Donald M. Stablein, Sanjay Phogat, David J. Venzon, Timothy Fouts, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2016) 197 (7): 2726–2737.
DOI: https://doi.org/10.4049/jimmunol.1600674
Published: 01 October 2016
View article titled, Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIV<sub>mac251</sub> Acquisition
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Includes: Supplementary data
Journal Articles

Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120

Matthew J. Blackburn, Ma Zhong-Min, Francesca Caccuri, Katherine McKinnon, Luca Schifanella, Yongjun Guan, Giacomo Gorini, David Venzon, Claudio Fenizia, Nicolò Binello, Shari N. Gordon, Christopher J. Miller, Genoveffa Franchini, Monica Vaccari
Journal: The Journal of Immunology
J Immunol (2015) 195 (7): 3227–3236.
DOI: https://doi.org/10.4049/jimmunol.1402699
Published: 01 October 2015
View article titled, Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120
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Includes: Supplementary data
Journal Articles

Antibody to the gp120 V1/V2 Loops and CD4+ and CD8+ T Cell Responses in Protection from SIVmac251 Vaginal Acquisition and Persistent Viremia

Shari N. Gordon, Melvin N. Doster, Rhonda C. Kines, Brandon F. Keele, Egidio Brocca-Cofano, Yongjun Guan, Poonam Pegu, Namal P. M. Liyanage, Monica Vaccari, Nicolas Cuburu, Christopher B. Buck, Guido Ferrari, David Montefiori, Michael Piatak, Jr., Jeffrey D. Lifson, Anastasia M. Xenophontos, David Venzon, Marjorie Robert-Guroff, Barney S. Graham, Douglas R. Lowy, John T. Schiller, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 6172–6183.
DOI: https://doi.org/10.4049/jimmunol.1401504
Published: 15 December 2014
View article titled, Antibody to the gp120 V1/V2 Loops and CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Responses in Protection from SIV<sub>mac251</sub> Vaginal Acquisition and Persistent Viremia
Open the PDF for Antibody to the gp120 V1/V2 Loops and CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Responses in Protection from SIV<sub>mac251</sub> Vaginal Acquisition and Persistent Viremia in another window
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Includes: Supplementary data
Journal Articles

A systems biology approach revealed distinct host responses between ALVAC-SIV and NYVAC-SIV vaccines during an evaluation of immunogenicity in rhesus macaques (VAC7P.992)

Yajie Yang, Shari Gordon, Melvin Doster, Namal Liyanage, Jean Chang, Chris Williams, Michael Agy, Randy Mclain, Brian Agricola, Lynn Law, Genoveffa Franchini, Robert Palermo, Michael Katze
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 141.37.
DOI: https://doi.org/10.4049/jimmunol.192.Supp.141.37
Published: 01 May 2014
View article titled, A systems biology approach revealed distinct host responses between ALVAC-SIV and NYVAC-SIV vaccines during an evaluation of immunogenicity in rhesus macaques (VAC7P.992)
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Journal Articles

Cutting Edge: Novel Vaccination Modality Provides Significant Protection against Mucosal Infection by Highly Pathogenic Simian Immunodeficiency Virus

Natasa Strbo, Monica Vaccari, Savita Pahwa, Michael A. Kolber, Melvin N. Doster, Eva Fisher, Louis Gonzalez, Donald Stablein, Genoveffa Franchini, Eckhard R. Podack
Journal: The Journal of Immunology
J Immunol (2013) 190 (6): 2495–2499.
DOI: https://doi.org/10.4049/jimmunol.1202655
Published: 15 March 2013
View article titled, Cutting Edge: Novel Vaccination Modality Provides Significant Protection against Mucosal Infection by Highly Pathogenic Simian Immunodeficiency Virus
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Includes: Supplementary data
Journal Articles

Targeting the Vaginal Mucosa with Human Papillomavirus Pseudovirion Vaccines Delivering Simian Immunodeficiency Virus DNA

Shari N. Gordon, Rhonda C. Kines, Galyna Kutsyna, Zhong-Min Ma, Anna Hryniewicz, Jeffery N. Roberts, Claudio Fenizia, Rachmat Hidajat, Egidio Brocca-Cofano, Nicolas Cuburu, Christopher B. Buck, Marcelino L. Bernardo, Marjorie Robert-Guroff, Christopher J. Miller, Barney S. Graham, Douglas R. Lowy, John T. Schiller, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2012) 188 (2): 714–723.
DOI: https://doi.org/10.4049/jimmunol.1101404
Published: 15 January 2012
View article titled, Targeting the Vaginal Mucosa with Human Papillomavirus Pseudovirion Vaccines Delivering Simian Immunodeficiency Virus DNA
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Journal Articles

Heat shock protein Gp96-Ig-peptide complexes based vaccine induce predominant immune responses at mucosal sites (46.13)

Natasa Strbo, Monica Vaccari, Savita Pahwa, Michael Kolber, Eva Fisher, Louis Gonzalez, Genoveffa Franchini, Eckhard Podack
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 46.13.
DOI: https://doi.org/10.4049/jimmunol.184.Supp.46.13
Published: 01 April 2010
View article titled, Heat shock protein Gp96-Ig-peptide complexes based vaccine induce predominant immune responses at mucosal sites (46.13)
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Journal Articles

Combined Effect of Antiretroviral Therapy and Blockade of IDO in SIV-Infected Rhesus Macaques

Adriano Boasso, Monica Vaccari, Dietmar Fuchs, Andrew W. Hardy, Wen-Po Tsai, Elzbieta Tryniszewska, Gene M. Shearer, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2009) 182 (7): 4313–4320.
DOI: https://doi.org/10.4049/jimmunol.0803314
Published: 01 April 2009
View article titled, Combined Effect of Antiretroviral Therapy and Blockade of IDO in SIV-Infected Rhesus Macaques
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Includes: Supplementary data
Journal Articles

Powerful mucosal immune response in macaques (Macaca mulatta) in response to SIV gp96-Ig immunization (39.35)

Natasa Strbo, Monica Vaccari, Savita Pahwa, Michael Kolber, Eva Fisher, Louis Gonzalez, Barbara Felber, George Pavlakis, Genoveffa Franchini, Eckhard Podack
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 39.35.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.39.35
Published: 01 April 2009
View article titled, Powerful mucosal immune response in macaques (Macaca mulatta) in response to SIV gp96-Ig immunization (39.35)
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Journal Articles

Immune Activation Driven by CTLA-4 Blockade Augments Viral Replication at Mucosal Sites in Simian Immunodeficiency Virus Infection

Valentina Cecchinato, Elzbieta Tryniszewska, Zhong Min Ma, Monica Vaccari, Adriano Boasso, Wen-Po Tsai, Constantinos Petrovas, Dietmar Fuchs, Jean-Michel Heraud, David Venzon, Gene M. Shearer, Richard A. Koup, Israel Lowy, Christopher J. Miller, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2008) 180 (8): 5439–5447.
DOI: https://doi.org/10.4049/jimmunol.180.8.5439
Published: 15 April 2008
View article titled, Immune Activation Driven by CTLA-4 Blockade Augments Viral Replication at Mucosal Sites in Simian Immunodeficiency Virus Infection
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Journal Articles

Interleukin-15 but Not Interleukin-7 Abrogates Vaccine-Induced Decrease in Virus Level in Simian Immunodeficiency Virusmac251-Infected Macaques

Anna Hryniewicz, David A. Price, Marcin Moniuszko, Adriano Boasso, Yvette Edghill-Spano, Sadie M. West, David Venzon, Monica Vaccari, Wen-Po Tsai, Elzbieta Tryniszewska, Janos Nacsa, Francois Villinger, Aftab A. Ansari, Christopher J. Trindade, Michel Morre, David Brooks, Philip Arlen, Helen J. Brown, Christina M. R. Kitchen, Jerome A. Zack, Daniel C. Douek, Gene M. Shearer, Mark G. Lewis, Richard A. Koup, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2007) 178 (6): 3492–3504.
DOI: https://doi.org/10.4049/jimmunol.178.6.3492
Published: 15 March 2007
View article titled, Interleukin-15 but Not Interleukin-7 Abrogates Vaccine-Induced Decrease in Virus Level in Simian Immunodeficiency Virus<sub>mac251</sub>-Infected Macaques
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Journal Articles

Subunit Recombinant Vaccine Protects against Monkeypox

In Special Collection:
Monkeypox and Other Poxvirus Articles
Jean-Michel Heraud, Yvette Edghill-Smith, Victor Ayala, Irene Kalisz, Janie Parrino, Vaniambadi S. Kalyanaraman, Jody Manischewitz, Lisa R. King, Anna Hryniewicz, Christopher J. Trindade, Meredith Hassett, Wen-Po Tsai, David Venzon, Aysegul Nalca, Monica Vaccari, Peter Silvera, Mike Bray, Barney S. Graham, Hana Golding, Jay W. Hooper, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2006) 177 (4): 2552–2564.
DOI: https://doi.org/10.4049/jimmunol.177.4.2552
Published: 15 August 2006
View article titled, Subunit Recombinant Vaccine Protects against Monkeypox
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Improved Vaccine Protection from Simian AIDS by the Addition of Nonstructural Simian Immunodeficiency Virus Genes

Zdeněk Hel, Wen-Po Tsai, Elzbieta Tryniszewska, Janos Nacsa, Phillip D. Markham, Mark G. Lewis, George N. Pavlakis, Barbara K. Felber, Jim Tartaglia, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2006) 176 (1): 85–96.
DOI: https://doi.org/10.4049/jimmunol.176.1.85
Published: 01 January 2006
View article titled, Improved Vaccine Protection from Simian AIDS by the Addition of Nonstructural Simian Immunodeficiency Virus Genes
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Journal Articles

Vaccine-Induced CD8+ Central Memory T Cells in Protection from Simian AIDS

Monica Vaccari, Christopher J. Trindade, David Venzon, Maurizio Zanetti, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2005) 175 (6): 3502–3507.
DOI: https://doi.org/10.4049/jimmunol.175.6.3502
Published: 15 September 2005
View article titled, Vaccine-Induced CD8<sup>+</sup> Central Memory T Cells in Protection from Simian AIDS
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Contrasting Effects of Low-Dose IL-2 on Vaccine-Boosted Simian Immunodeficiency Virus (SIV)-Specific CD4+ and CD8+ T Cells in Macaques Chronically Infected with SIVmac251

Janos Nacsa, Yvette Edghill-Smith, Wen-Po Tsai, David Venzon, Elzbieta Tryniszewska, Anna Hryniewicz, Marcin Moniuszko, Audrey Kinter, Kendall A. Smith, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2005) 174 (4): 1913–1921.
DOI: https://doi.org/10.4049/jimmunol.174.4.1913
Published: 15 February 2005
View article titled, Contrasting Effects of Low-Dose IL-2 on Vaccine-Boosted Simian Immunodeficiency Virus (SIV)-Specific CD4<sup>+</sup> and CD8<sup>+</sup> T Cells in Macaques Chronically Infected with SIVmac251
Open the PDF for Contrasting Effects of Low-Dose IL-2 on Vaccine-Boosted Simian Immunodeficiency Virus (SIV)-Specific CD4<sup>+</sup> and CD8<sup>+</sup> T Cells in Macaques Chronically Infected with SIVmac251 in another window
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Vaccination of Macaques with Long-Standing SIVmac251 Infection Lowers the Viral Set Point After Cessation of Antiretroviral Therapy

Elzbieta Tryniszewska, Janos Nacsa, Mark G. Lewis, Peter Silvera, David Montefiori, David Venzon, Zdeněk Hel, Robyn Washington Parks, Marcin Moniuszko, Jim Tartaglia, Kendall A. Smith, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2002) 169 (9): 5347–5357.
DOI: https://doi.org/10.4049/jimmunol.169.9.5347
Published: 01 November 2002
View article titled, Vaccination of Macaques with Long-Standing SIVmac251 Infection Lowers the Viral Set Point After Cessation of Antiretroviral Therapy
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Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4+ and CD8+ T Cell Responses

Zdenek Hel, Janos Nacsa, Elzbieta Tryniszewska, Wen-Po Tsai, Robyn Washington Parks, David C. Montefiori, Barbara K. Felber, James Tartaglia, George N. Pavlakis, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2002) 169 (9): 4778–4787.
DOI: https://doi.org/10.4049/jimmunol.169.9.4778
Published: 01 November 2002
View article titled, Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Responses
Open the PDF for Containment of Simian Immunodeficiency Virus Infection in Vaccinated Macaques: Correlation with the Magnitude of Virus-Specific Pre- and Postchallenge CD4<sup>+</sup> and CD8<sup>+</sup> T Cell Responses in another window
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