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Geoffrey T. Hart
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Journal Articles

NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children

Jenna K. Dick, Jules A. Sangala, Venkatramana D. Krishna, Aaron Khaimraj, Lydia Hamel, Spencer M. Erickson, Dustin Hicks, Yvette Soigner, Laura E. Covill, Alexander K. Johnson, Michael J. Ehrhardt, Keenan Ernste, Petter Brodin, Richard A. Koup, Alka Khaitan, Carly Baehr, Beth K. Thielen, Christine M. Henzler, Caleb Skipper, Jeffrey S. Miller, Yenan T. Bryceson, Jianming Wu, Chandy C. John, Angela Panoskaltsis-Mortari, Alberto Orioles, Marie E. Steiner, Maxim C. J. Cheeran, Marco Pravetoni, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2024) 213 (10): 1452–1466.
https://doi.org/10.4049/jimmunol.2400395
Published: 11 October 2024
View article titled, NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children
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Includes: Supplementary data
Journal Articles

Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production

James D. Dahlvang, Jenna K. Dick, Jules A. Sangala, Philippa R. Kennedy, Emily J. Pomeroy, Kristin M. Snyder, Juliette M. Moushon, Claire E. Thefaine, Jianming Wu, Sara E. Hamilton, Martin Felices, Jeffrey S. Miller, Bruce Walcheck, Beau R. Webber, Branden S. Moriarity, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2023) 210 (8): 1108–1122.
https://doi.org/10.4049/jimmunol.2200488
Published: 06 March 2023
View article titled, Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production
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Includes: Supplementary data
Journal Articles

Contribution of Antibody-Mediated Effector Functions to the Mechanism of Efficacy of Vaccines for Opioid Use Disorders

April M. Huseby Kelcher, Carly A. Baehr, Fatima A. Hamid, Geoffrey T. Hart, Marco Pravetoni
Journal: The Journal of Immunology
J Immunol (2021) 207 (3): 860–867.
https://doi.org/10.4049/jimmunol.2100204
Published: 01 August 2021
View article titled, Contribution of Antibody-Mediated Effector Functions to the Mechanism of Efficacy of Vaccines for Opioid Use Disorders
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Includes: Supplementary data
Journal Articles

Using CRISPR/cas9 in primary natural killer cells to study antibody dependent cellular cytotoxicity signaling.

James D. Dahlvang, Jules A. Sangala, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 97.14.
https://doi.org/10.4049/jimmunol.206.Supp.97.14
Published: 01 May 2021
View article titled, Using CRISPR/cas9 in primary natural killer cells to study antibody dependent cellular cytotoxicity signaling.
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Journal Articles

Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses

In Special Collection:
COVID-19, SARS, and MERS Articles
Vineet Joag, Sathi Wijeyesinghe, J. Michael Stolley, Clare F. Quarnstrom, Thamotharampillai Dileepan, Andrew G. Soerens, Jules A. Sangala, Stephen D. O’Flanagan, Noah V. Gavil, Sung-Wook Hong, Siddheshvar Bhela, Sailaja Gangadhara, Eyob Weyu, William E. Matchett, Joshua Thiede, Venkatramana Krishna, Maxim C.-J. Cheeran, Tyler D. Bold, Rama Amara, Peter Southern, Geoffrey T. Hart, Luca Schifanella, Vaiva Vezys, Marc K. Jenkins, Ryan A. Langlois, David Masopust
Journal: The Journal of Immunology
J Immunol (2021) 206 (5): 931–935.
https://doi.org/10.4049/jimmunol.2001400
Published: 01 March 2021
View article titled, Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses
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Includes: Supplementary data
Journal Articles

Patients with Natural Killer (NK) Cell Chronic Active Epstein-Barr Virus Have a Unique Phenotype, With Increased Activation of the PI3K/Akt/mTOR and STAT1 Pathways and Immature NK Cells

K C Dowdell, Matthew Howe, Hyesun Kuehn, Geoffrey T Hart, Amy Hsu, Hua Su, Julie Niemela, Gulbu Uzel, Evan Shereck, Laura Schulz, Tatyana Feldman, Jennifer Stoddard, Sergio Rosenzweig, Eric O Long, Lesia Dropulic, Jeffrey Cohen
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 76.16.
https://doi.org/10.4049/jimmunol.202.Supp.76.16
Published: 01 May 2019
View article titled, Patients with Natural Killer (NK) Cell Chronic Active Epstein-Barr Virus Have a Unique Phenotype, With Increased Activation of the PI3K/Akt/mTOR and STAT1 Pathways and Immature NK Cells
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Journal Articles

A new malaria killer: Fc receptor gamma chain and PLZF identify NK cell subsets that correlate with reduced Plasmodium falciparum parasitemia and increased antibody dependent cellular cytotoxicity against opsonized infected RBCs.

Geoffrey T. Hart, Tuan Tran, Jakob Theorell, Gunjan Arora, Peter Crompton, Yenan Bryceson, Eric O. Long
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 168.17.
https://doi.org/10.4049/jimmunol.200.Supp.168.17
Published: 01 May 2018
View article titled, A new malaria killer: Fc receptor gamma chain and PLZF identify NK cell subsets that correlate with reduced <em>Plasmodium falciparum</em> parasitemia and increased antibody dependent cellular cytotoxicity against opsonized infected RBCs.
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Journal Articles

Antibody-dependent NK cell control of Plasmodium falciparum infection

Geoffrey T Hart, Jakob Theorell, Tuan Tran, Gunjan Arora, Peter D Crompton, Yenan Bryceson, Eric O Long
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 68.19.
https://doi.org/10.4049/jimmunol.198.Supp.68.19
Published: 01 May 2017
View article titled, Antibody-dependent NK cell control of <em>Plasmodium falciparum</em> infection
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Journal Articles

IL-15 complex-stimulated NK cells protect mice from cerebral malaria

Kristina Stoermer Burrack, Matthew A Huggins, Geoffrey T Hart, Aaron J Johnson, Stephen C Jameson, Sara E Hamilton
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 123.3.
https://doi.org/10.4049/jimmunol.198.Supp.123.3
Published: 01 May 2017
View article titled, IL-15 complex-stimulated NK cells protect mice from cerebral malaria
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Journal Articles

The Regulation of Inherently Autoreactive VH4-34–Expressing B Cells in Individuals Living in a Malaria-Endemic Area of West Africa

Geoffrey T. Hart, Munir Akkaya, Asiya S. Chida, Chungwen Wei, Scott A. Jenks, Christopher Tipton, Chenfeng He, Ben S. Wendel, Jeff Skinner, Gunjan Arora, Kassoum Kayentao, Aissata Ongoiba, Ogobara Doumbo, Boubacar Traore, David L. Narum, Ning Jiang, Peter D. Crompton, Ignacio Sanz, Susan K. Pierce
Journal: The Journal of Immunology
J Immunol (2016) 197 (10): 3841–3849.
https://doi.org/10.4049/jimmunol.1600491
Published: 15 November 2016
View article titled, The Regulation of Inherently Autoreactive VH4-34–Expressing B Cells in Individuals Living in a Malaria-Endemic Area of West Africa
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Includes: Supplementary data
Journal Articles

Natural Killer cell-mediated antibody-dependent cellular cytotoxicity towards red blood cells infected by Plasmodium falciparum

Gunjan Arora, Geoffrey T. Hart, Sanjay A. Desai, Eric O Long
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 197.3.
https://doi.org/10.4049/jimmunol.196.Supp.197.3
Published: 01 May 2016
View article titled, Natural Killer cell-mediated antibody-dependent cellular cytotoxicity towards red blood cells infected by <em>Plasmodium falciparum</em>
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Journal Articles

Antigen-dependent engagement of brain endothelium by CD8 T cells leads to fatal brainstem pathology during cerebral malaria

Phillip A Swanson, Geoffrey T Hart, Matthew V Russo, Susan K Pierce, Dorian B McGavern
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 134.1.
https://doi.org/10.4049/jimmunol.196.Supp.134.1
Published: 01 May 2016
View article titled, Antigen-dependent engagement of brain endothelium by CD8 T cells leads to fatal brainstem pathology during cerebral malaria
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Journal Articles

Cutting Edge: Krüppel-like Factor 2 Is Required for Phenotypic Maintenance but Not Development of B1 B Cells

Geoffrey T. Hart, Stephen L. Peery, Sara E. Hamilton, Stephen C. Jameson
Journal: The Journal of Immunology
J Immunol (2012) 189 (7): 3293–3297.
https://doi.org/10.4049/jimmunol.1201439
Published: 01 October 2012
View article titled, Cutting Edge: Krüppel-like Factor 2 Is Required for Phenotypic Maintenance but Not Development of B1 B Cells
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Includes: Supplementary data
Journal Articles

Krüppel-like Factors in Lymphocyte Biology

In Special Collection:
Brief Reviews
Geoffrey T. Hart, Kristin A. Hogquist, Stephen C. Jameson
Journal: The Journal of Immunology
J Immunol (2012) 188 (2): 521–526.
https://doi.org/10.4049/jimmunol.1101530
Published: 15 January 2012
View article titled, Krüppel-like Factors in Lymphocyte Biology
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Journal Articles

Kruppel-Like Factor 2 Is Required for Trafficking but Not Quiescence in Postactivated T Cells

Kensuke Takada, Xiaodan Wang, Geoffrey T. Hart, Oludare A. Odumade, Michael A. Weinreich, Kristin A. Hogquist, Stephen C. Jameson
Journal: The Journal of Immunology
J Immunol (2011) 186 (2): 775–783.
https://doi.org/10.4049/jimmunol.1000094
Published: 15 January 2011
View article titled, Kruppel-Like Factor 2 Is Required for Trafficking but Not Quiescence in Postactivated T Cells
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Includes: Supplementary data