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Overexpression of Transmembrane TNF Drives Development of Ectopic Lymphoid Structures in the Bone Marrow and B Cell Lineage Alterations in Experimental Spondyloarthritis

Merlijn H. Kaaij, Jasper Rip, Kim C. M. Jeucken, Yik Y. Kan, Charlotte C. N. van Rooijen, Job Saris, Desiree Pots, Silke Frey, Joep Grootjans, Georg Schett, Leonie M. van Duivenvoorde, Martijn A. Nolte, Rudi W. Hendriks, Odilia B. J. Corneth, Jan Piet van Hamburg, Dominique L. P. Baeten, Sander W. Tas

J Immunol (2021) 207 (9): 2337–2346.

DOI: https://doi.org/10.4049/jimmunol.2100512

Published: 01 November 2021

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Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis

Alina Soare, Stefanie Weber, Lisa Maul, Simon Rauber, Ana Maria Gheorghiu, Markus Luber, Ismail Houssni, Arnd Kleyer, Gero von Pickardt, Manuel Gado, David Simon, Jürgen Rech, Georg Schett, Jörg H. W. Distler, Andreas Ramming

J Immunol (2018) 200 (4): 1249–1254.

DOI: https://doi.org/10.4049/jimmunol.1700596

Published: 15 February 2018

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The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

Tobias Rothe, Natacha Ipseiz, Maria Faas, Stefanie Lang, Francesc Perez-Branguli, Daniel Metzger, Hiroshi Ichinose, Beate Winner, Georg Schett, Gerhard Krönke

J Immunol (2017) 198 (10): 3878–3885.

DOI: https://doi.org/10.4049/jimmunol.1600638

Published: 15 May 2017

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Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption

Nikolaus Binder, Christine Miller, Masaki Yoshida, Kazuki Inoue, Shinichi Nakano, Xiaoyu Hu, Lionel B. Ivashkiv, Georg Schett, Alessandra Pernis, Steven R. Goldring, F. Patrick Ross, Baohong Zhao

J Immunol (2017) 198 (9): 3436–3447.

DOI: https://doi.org/10.4049/jimmunol.1601716

Published: 01 May 2017

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The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages

Nicole Hannemann, Jutta Jordan, Sushmita Paul, Stephen Reid, Hanns-Wolf Baenkler, Sophia Sonnewald, Tobias Bäuerle, Julio Vera, Georg Schett, Aline Bozec

J Immunol (2017) 198 (9): 3605–3614.

DOI: https://doi.org/10.4049/jimmunol.1601330

Published: 01 May 2017

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Neurodegeneration Enhances the Development of Arthritis

Stefanie C. Lang, Ulrike Harre, Pavitra Purohit, Katharina Dietel, Deborah Kienhöfer, Jonas Hahn, Wolfgang Baum, Martin Herrmann, Georg Schett, Dirk Mielenz

J Immunol (2017) 198 (6): 2394–2402.

DOI: https://doi.org/10.4049/jimmunol.1601472

Published: 15 March 2017

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Reduced Fluorescence versus Forward Scatter Time-of-Flight and Increased Peak versus Integral Fluorescence Ratios Indicate Receptor Clustering in Flow Cytometry

Barbara G. Fürnrohr, Merle Stein, Benjamin Rhodes, Prabhjoat S. Chana, Georg Schett, Timothy J. Vyse, Martin Herrmann, Dirk Mielenz

J Immunol (2015) 195 (1): 377–385.

DOI: https://doi.org/10.4049/jimmunol.1401889

Published: 01 July 2015

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Inhibition of Bone Remodeling in Young Mice by Bisphosphonate Displaces the Plasma Cell Niche into the Spleen

Stefan Teufel, Bettina Grötsch, Julia Luther, Anja Derer, Thorsten Schinke, Michael Amling, Georg Schett, Dirk Mielenz, Jean-Pierre David

J Immunol (2014) 193 (1): 223–233.

DOI: https://doi.org/10.4049/jimmunol.1302713

Published: 01 July 2014

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The Nuclear Receptor Nr4a1 Mediates Anti-Inflammatory Effects of Apoptotic Cells

Natacha Ipseiz, Stefan Uderhardt, Carina Scholtysek, Martin Steffen, Gernot Schabbauer, Aline Bozec, Georg Schett, Gerhard Krönke

J Immunol (2014) 192 (10): 4852–4858.

DOI: https://doi.org/10.4049/jimmunol.1303377

Published: 15 May 2014

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The AP-1 transcription factor Fra-1 is a negative regulator of B2B cell proliferation and of immunoglobulin class switch (111.49)

Bettina Groetsch, Christiane Lang, Kirsten Neubert, Sebastian Brachs, Christine Zech, Anja Derer, Julia Luther, David Voehringer, Erwin Wagner, Georg Schett, Dirk Mielenz, Jean-Pierre David

J Immunol (2012) 188 (1_Supplement): 111.49.

DOI: https://doi.org/10.4049/jimmunol.188.Supp.111.49

Published: 01 May 2012

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IL-33 Shifts the Balance from Osteoclast to Alternatively Activated Macrophage Differentiation and Protects from TNF-α–Mediated Bone Loss

Mario M. Zaiss, Mariola Kurowska-Stolarska, Christina Böhm, Regina Gary, Carina Scholtysek, Bartosz Stolarski, James Reilly, Shauna Kerr, Neal L. Millar, Thomas Kamradt, Iain B. McInnes, Padraic G. Fallon, Jean-Pierre David, Foo Y. Liew, Georg Schett

J Immunol (2011) 186 (11): 6097–6105.

DOI: https://doi.org/10.4049/jimmunol.1003487

Published: 01 June 2011

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Response to Comment on “Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis”

Georg Schett

J Immunol (2011) 186 (1): 3–4.

DOI: https://doi.org/10.4049/jimmunol.1090116

Published: 01 January 2011

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The Early Marginal Zone B Cell-Initiated T-Independent Type 2 Response Resists the Proteasome Inhibitor Bortezomib

Veronika R. Lang, Dirk Mielenz, Kirsten Neubert, Christina Böhm, Georg Schett, Hans-Martin Jäck, Reinhard E. Voll, Silke Meister

J Immunol (2010) 185 (9): 5637–5647.

DOI: https://doi.org/10.4049/jimmunol.1001040

Published: 01 November 2010

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Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis

Mario M. Zaiss, Benjamin Frey, Andreas Hess, Jochen Zwerina, Julia Luther, Falk Nimmerjahn, Klaus Engelke, George Kollias, Thomas Hünig, Georg Schett, Jean-Pierre David

J Immunol (2010) 184 (12): 7238–7246.

DOI: https://doi.org/10.4049/jimmunol.0903841

Published: 15 June 2010

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The α-Isoform of p38 MAPK Specifically Regulates Arthritic Bone Loss

Christina Böhm, Silvia Hayer, Anita Kilian, Mario M. Zaiss, Susann Finger, Andreas Hess, Klaus Engelke, George Kollias, Gerhard Krönke, Jochen Zwerina, Georg Schett, Jean-Pierre David

J Immunol (2009) 183 (9): 5938–5947.

DOI: https://doi.org/10.4049/jimmunol.0901026

Published: 01 November 2009

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12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

Gerhard Krönke, Julia Katzenbeisser, Stefan Uderhardt, Mario M. Zaiss, Carina Scholtysek, Gernot Schabbauer, Alexander Zarbock, Marije I. Koenders, Roland Axmann, Jochen Zwerina, Hans W. Baenckler, Wim van den Berg, Reinhard E. Voll, Hartmut Kühn, Leo A. B. Joosten, Georg Schett

J Immunol (2009) 183 (5): 3383–3389.

DOI: https://doi.org/10.4049/jimmunol.0900327

Published: 01 September 2009

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Role of MAPK Kinase 6 in Arthritis: Distinct Mechanism of Action in Inflammation and Cytokine Expression

Toshio Yoshizawa, Deepa Hammaker, David L. Boyle, Maripat Corr, Richard Flavell, Roger Davis, Georg Schett, Gary S. Firestein

J Immunol (2009) 183 (2): 1360–1367.

DOI: https://doi.org/10.4049/jimmunol.0900483

Published: 15 July 2009

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The Rheumatoid Arthritis-Associated Autoantigen hnRNP-A2 (RA33) Is a Major Stimulator of Autoimmunity in Rats with Pristane-Induced Arthritis

Markus H. Hoffmann, Jonatan Tuncel, Karl Skriner, Makiyeh Tohidast-Akrad, Birgit Türk, Serafin Pinol-Roma, Guy Serre, Georg Schett, Josef S. Smolen, Rikard Holmdahl, Günter Steiner

J Immunol (2007) 179 (11): 7568–7576.

DOI: https://doi.org/10.4049/jimmunol.179.11.7568

Published: 01 December 2007

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Aberrant Expression of the Autoantigen Heterogeneous Nuclear Ribonucleoprotein-A2 (RA33) and Spontaneous Formation of Rheumatoid Arthritis-Associated Anti-RA33 Autoantibodies in TNF-α Transgenic Mice

Silvia Hayer, Makiyeh Tohidast-Akrad, Silva Haralambous, Beatrice Jahn-Schmid, Karl Skriner, Sylvie Trembleau, Hélène Dumortier, Serafin Pinol-Roma, Kurt Redlich, Georg Schett, Sylviane Muller, George Kollias, Josef Smolen, Günter Steiner

J Immunol (2005) 175 (12): 8327–8336.

DOI: https://doi.org/10.4049/jimmunol.175.12.8327

Published: 15 December 2005

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Interaction between Synovial Inflammatory Tissue and Bone Marrow in Rheumatoid Arthritis

Esther Jimenez-Boj, Kurt Redlich, Birgit Türk, Beatrice Hanslik-Schnabel, Axel Wanivenhaus, Andreas Chott, Josef S. Smolen, Georg Schett

J Immunol (2005) 175 (4): 2579–2588.

DOI: https://doi.org/10.4049/jimmunol.175.4.2579

Published: 15 August 2005

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NARROW

Overexpression of Transmembrane TNF Drives Development of Ectopic Lymphoid Structures in the Bone Marrow and B Cell Lineage Alterations in Experimental Spondyloarthritis

Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis

The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption

The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages

Neurodegeneration Enhances the Development of Arthritis

Reduced Fluorescence versus Forward Scatter Time-of-Flight and Increased Peak versus Integral Fluorescence Ratios Indicate Receptor Clustering in Flow Cytometry

Inhibition of Bone Remodeling in Young Mice by Bisphosphonate Displaces the Plasma Cell Niche into the Spleen

The Nuclear Receptor Nr4a1 Mediates Anti-Inflammatory Effects of Apoptotic Cells

The AP-1 transcription factor Fra-1 is a negative regulator of B2B cell proliferation and of immunoglobulin class switch (111.49)

IL-33 Shifts the Balance from Osteoclast to Alternatively Activated Macrophage Differentiation and Protects from TNF-α–Mediated Bone Loss

Response to Comment on “Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis”

The Early Marginal Zone B Cell-Initiated T-Independent Type 2 Response Resists the Proteasome Inhibitor Bortezomib

Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis

The α-Isoform of p38 MAPK Specifically Regulates Arthritic Bone Loss

12/15-Lipoxygenase Counteracts Inflammation and Tissue Damage in Arthritis

Role of MAPK Kinase 6 in Arthritis: Distinct Mechanism of Action in Inflammation and Cytokine Expression

The Rheumatoid Arthritis-Associated Autoantigen hnRNP-A2 (RA33) Is a Major Stimulator of Autoimmunity in Rats with Pristane-Induced Arthritis

Aberrant Expression of the Autoantigen Heterogeneous Nuclear Ribonucleoprotein-A2 (RA33) and Spontaneous Formation of Rheumatoid Arthritis-Associated Anti-RA33 Autoantibodies in TNF-α Transgenic Mice

Interaction between Synovial Inflammatory Tissue and Bone Marrow in Rheumatoid Arthritis

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