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George F. Gao
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Journal Articles

Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape

Yingze Zhao, Wenling Xiao, Yanan Wu, Wenhui Fan, Lei Li, Can Yue, Qingxu Zhang, Danni Zhang, Xiaoju Yuan, Sijia Yao, Sai Liu, Min Li, Pengyan Wang, Hangjie Zhang, Jie Zhang, Min Zhao, Xiaoqun Zheng, Wenjun Liu, George F. Gao, William J. Liu
Journal: The Journal of Immunology
J Immunol (2023) 210 (8): 1074–1085.
https://doi.org/10.4049/jimmunol.2200243
Published: 10 March 2023
View article titled, Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape
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Includes: Supplementary data
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A Wider and Deeper Peptide-Binding Groove for the Class I Molecules from B15 Compared with B19 Chickens Correlates with Relative Resistance to Marek’s Disease

Lingxia Han, Shaolian Wu, Ting Zhang, Weiyu Peng, Min Zhao, Can Yue, Wanxin Wen, Wenbo Cai, Min Li, Hans-Joachim Wallny, David W. Avila, William Mwangi, Venugopal Nair, Nicola Ternette, Yaxin Guo, Yingze Zhao, Yan Chai, Jianxun Qi, Hao Liang, George F. Gao, Jim Kaufman, William J. Liu
Journal: The Journal of Immunology
J Immunol (2023) 210 (5): 668–680.
https://doi.org/10.4049/jimmunol.2200211
Published: 25 January 2023
View article titled, A Wider and Deeper Peptide-Binding Groove for the Class I Molecules from B15 Compared with B19 Chickens Correlates with Relative Resistance to Marek’s Disease
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Includes: Supplementary data
Journal Articles

Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors

Keke Ma, Yan Chai, Jiawei Guan, Shuguang Tan, Jianxun Qi, Ai Kawana-Tachikawa, Tao Dong, Aikichi Iwamoto, Yi Shi, George F. Gao
Journal: The Journal of Immunology
J Immunol (2022) 209 (9): 1652–1661.
https://doi.org/10.4049/jimmunol.2200191
Published: 01 November 2022
View article titled, Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors
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Includes: Supplementary data
Journal Articles

Pneumonia Severity and Phase Linked to Virus-Specific T Cell Responses with Distinct Immune Checkpoints during pH1N1 Infection

Hui Li, Min Zhao, Hangjie Zhang, Chuansong Quan, Dannie Zhang, Yingmei Liu, Meng Liu, Chunxue Xue, Shuguang Tan, Yaxin Guo, Yingze Zhao, Guizhen Wu, George F. Gao, Bin Cao, William J. Liu
Journal: The Journal of Immunology
J Immunol (2022) 208 (9): 2154–2162.
https://doi.org/10.4049/jimmunol.2101021
Published: 01 May 2022
View article titled, Pneumonia Severity and Phase Linked to Virus-Specific T Cell Responses with Distinct Immune Checkpoints during pH1N1 Infection
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Includes: Supplementary data
Journal Articles

Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats

Pengyan Wang, Can Yue, Kefang Liu, Dan Lu, Sai Liu, Sijia Yao, Xin Li, Xiaoling Su, Keyi Ren, Yan Chai, Jianxun Qi, Yingze Zhao, Yongliang Lou, Zeyu Sun, George F. Gao, William J. Liu
Journal: The Journal of Immunology
J Immunol (2021) 207 (8): 2167–2178.
https://doi.org/10.4049/jimmunol.2100350
Published: 15 October 2021
View article titled, Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats
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Includes: Supplementary data
Journal Articles

Structural and functional insights of the capsid protein from Zika virus

Hao Song, Zifang Shang, Jianxun Qi, George F. Gao
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 197.26.
https://doi.org/10.4049/jimmunol.202.Supp.197.26
Published: 01 May 2019
View article titled, Structural and functional insights of the capsid protein from Zika virus
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Journal Articles

An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I

Jin Xiao, Wangzhen Xiang, Yongli Zhang, Weiyu Peng, Min Zhao, Ling Niu, Yan Chai, Jianxun Qi, Fei Wang, Peng Qi, Chungang Pan, Lingxia Han, Ming Wang, Jim Kaufman, George F. Gao, William J. Liu
Journal: The Journal of Immunology
J Immunol (2018) 201 (10): 3084–3095.
https://doi.org/10.4049/jimmunol.1800611
Published: 15 November 2018
View article titled, An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I
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Includes: Supplementary data
Journal Articles

Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus–Derived CD8+ T Cell Epitopes and Host MHC

In Special Collection:
COVID-19, SARS, and MERS Articles
William J. Liu, Jiaming Lan, Kefang Liu, Yao Deng, Yanfeng Yao, Shaolian Wu, Hong Chen, Lingling Bao, Haifeng Zhang, Min Zhao, Qihui Wang, Lingxia Han, Yan Chai, Jianxun Qi, Jincun Zhao, Songdong Meng, Chuan Qin, George F. Gao, Wenjie Tan
Journal: The Journal of Immunology
J Immunol (2017) 198 (2): 873–882.
https://doi.org/10.4049/jimmunol.1601542
Published: 15 January 2017
View article titled, Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus–Derived CD8<sup>+</sup> T Cell Epitopes and Host MHC
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Includes: Supplementary data
Journal Articles

Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I

Jin Xiao, Wangzhen Xiang, Yan Chai, Joel Haywood, Jianxun Qi, Limin Ba, Peng Qi, Ming Wang, Jun Liu, George F. Gao
Journal: The Journal of Immunology
J Immunol (2016) 197 (6): 2306–2315.
https://doi.org/10.4049/jimmunol.1600887
Published: 15 September 2016
View article titled, Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
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Includes: Supplementary data
Journal Articles

TCRklass: A New K-String–Based Algorithm for Human and Mouse TCR Repertoire Characterization

Xi Yang, Di Liu, Na Lv, Fangqing Zhao, Fei Liu, Jing Zou, Yan Chen, Xue Xiao, Jun Wu, Peipei Liu, Jing Gao, Yongfei Hu, Yi Shi, Jun Liu, Ruifen Zhang, Chen Chen, Juncai Ma, George F. Gao, Baoli Zhu
Journal: The Journal of Immunology
J Immunol (2015) 194 (1): 446–454.
https://doi.org/10.4049/jimmunol.1400711
Published: 01 January 2015
View article titled, TCRklass: A New K-String–Based Algorithm for Human and Mouse TCR Repertoire Characterization
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Includes: Supplementary data
Journal Articles

Superimposed Epitopes Restricted by the Same HLA Molecule Drive Distinct HIV-Specific CD8+ T Cell Repertoires

Xiaoming Sun, Mamoru Fujiwara, Yi Shi, Nozomi Kuse, Hiroyuki Gatanaga, Victor Appay, George F. Gao, Shinichi Oka, Masafumi Takiguchi
Journal: The Journal of Immunology
J Immunol (2014) 193 (1): 77–84.
https://doi.org/10.4049/jimmunol.1400375
Published: 01 July 2014
View article titled, Superimposed Epitopes Restricted by the Same HLA Molecule Drive Distinct HIV-Specific CD8<sup>+</sup> T Cell Repertoires
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Includes: Supplementary data
Journal Articles

Nα-Terminal Acetylation for T Cell Recognition: Molecular Basis of MHC Class I–Restricted Nα-Acetylpeptide Presentation

Mingwei Sun, Jun Liu, Jianxun Qi, Boris Tefsen, Yi Shi, Jinghua Yan, George F. Gao
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5509–5519.
https://doi.org/10.4049/jimmunol.1400199
Published: 15 June 2014
View article titled, N<sup>α</sup>-Terminal Acetylation for T Cell Recognition: Molecular Basis of MHC Class I–Restricted N<sup>α</sup>-Acetylpeptide Presentation
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Includes: Supplementary data
Journal Articles

Lyn Mitigates Mouse Airway Remodeling by Downregulating the TGF-β3 Isoform in House Dust Mite Models

Guoping Li, John Fox, III, Zhigang Liu, Jun Liu, George F. Gao, Yang Jin, Hongwei Gao, Min Wu
Journal: The Journal of Immunology
J Immunol (2013) 191 (11): 5359–5370.
https://doi.org/10.4049/jimmunol.1301596
Published: 01 December 2013
View article titled, Lyn Mitigates Mouse Airway Remodeling by Downregulating the TGF-β3 Isoform in House Dust Mite Models
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Includes: Supplementary data
Journal Articles

VP2 Dominated CD4+ T Cell Responses against Enterovirus 71 and Cross-Reactivity against Coxsackievirus A16 and Polioviruses in a Healthy Population

Shuguang Tan, Xiaojuan Tan, Xiaoman Sun, Guangwen Lu, Chun-Chi Chen, Jinghua Yan, Jun Liu, Wenbo Xu, George F. Gao
Journal: The Journal of Immunology
J Immunol (2013) 191 (4): 1637–1647.
https://doi.org/10.4049/jimmunol.1301439
Published: 15 August 2013
View article titled, VP2 Dominated CD4<sup>+</sup> T Cell Responses against Enterovirus 71 and Cross-Reactivity against Coxsackievirus A16 and Polioviruses in a Healthy Population
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Includes: Supplementary data
Journal Articles

Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens

Jianhua Zhang, Yong Chen, Jianxun Qi, Feng Gao, Yanjie Liu, Jun Liu, Xuyu Zhou, Jim Kaufman, Chun Xia, George F. Gao
Journal: The Journal of Immunology
J Immunol (2012) 189 (9): 4478–4487.
https://doi.org/10.4049/jimmunol.1200885
Published: 01 November 2012
View article titled, Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens
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Journal Articles

Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226

Jun Liu, Xiaomin Qian, Zhujun Chen, Xiang Xu, Feng Gao, Shuijun Zhang, Rongguang Zhang, Jianxun Qi, George F. Gao, Jinghua Yan
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5511–5520.
https://doi.org/10.4049/jimmunol.1200324
Published: 01 June 2012
View article titled, Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
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Journal Articles

Structural Basis of Diverse Peptide Accommodation by the Rhesus Macaque MHC Class I Molecule Mamu-B*17: Insights into Immune Protection from Simian Immunodeficiency Virus

Yan Wu, Feng Gao, Jun Liu, Jianxun Qi, Emma Gostick, David A. Price, George F. Gao
Journal: The Journal of Immunology
J Immunol (2011) 187 (12): 6382–6392.
https://doi.org/10.4049/jimmunol.1101726
Published: 15 December 2011
View article titled, Structural Basis of Diverse Peptide Accommodation by the Rhesus Macaque MHC Class I Molecule Mamu-B*17: Insights into Immune Protection from Simian Immunodeficiency Virus
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Journal Articles

MHC Class I Presentation and Regulation by IFN in Bony Fish Determined by Molecular Analysis of the Class I Locus in Grass Carp

Weihong Chen, Zhenghu Jia, Ting Zhang, Nianzhi Zhang, Changyou Lin, Feng Gao, Li Wang, Xiaoying Li, Yinan Jiang, Xin Li, George F. Gao, Chun Xia
Journal: The Journal of Immunology
J Immunol (2010) 185 (4): 2209–2221.
https://doi.org/10.4049/jimmunol.1000347
Published: 15 August 2010
View article titled, MHC Class I Presentation and Regulation by IFN in Bony Fish Determined by Molecular Analysis of the Class I Locus in Grass Carp
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Includes: Supplementary data
Journal Articles

Escaping neutralization and gaining adaptation of highly pathogenic avian influenza (HPAI) H5N1 virus in interspecies evolution. (92.5)

Wei He, Zheng Li, Zhonghua Liu, Linqi Zhang, Yuelong Su, George F Gao, Zi Li, Lianxian Cui
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 92.5.
https://doi.org/10.4049/jimmunol.184.Supp.92.5
Published: 01 April 2010
View article titled, Escaping neutralization and gaining adaptation of highly pathogenic avian influenza (HPAI) H5N1 virus in interspecies evolution. (92.5)
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Journal Articles

Human TCR-Binding Affinity is Governed by MHC Class Restriction

David K. Cole, Nicholas J. Pumphrey, Jonathan M. Boulter, Malkit Sami, John I. Bell, Emma Gostick, David A. Price, George F. Gao, Andrew K. Sewell, Bent K. Jakobsen
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5727–5734.
https://doi.org/10.4049/jimmunol.178.9.5727
Published: 01 May 2007
View article titled, Human TCR-Binding Affinity is Governed by MHC Class Restriction
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