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George S. Yap
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Journal Articles

Emerging Roles of Growth Differentiation Factor 15 in Immunoregulation and Pathogenesis

Jojo Reyes, George S. Yap
Journal: The Journal of Immunology
J Immunol (2023) 210 (1): 5–11.
https://doi.org/10.4049/jimmunol.2200641
Published: 01 January 2023
View article titled, Emerging Roles of Growth Differentiation Factor 15 in Immunoregulation and Pathogenesis
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Journal Articles

The Impact of Helminth Coinfection on Innate and Adaptive Immune Resistance and Disease Tolerance during Toxoplasmosis

Eliezer Rovira-Diaz, Darine W. El-Naccache, Jojo Reyes, Yanlin Zhao, Azadeh Nasuhidehnavi, Fei Chen, William C. Gause, George S. Yap
Journal: The Journal of Immunology
J Immunol (2022) 209 (11): 2160–2171.
https://doi.org/10.4049/jimmunol.2200504
Published: 01 December 2022
View article titled, The Impact of Helminth Coinfection on Innate and Adaptive Immune Resistance and Disease Tolerance during Toxoplasmosis
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Includes: Supplementary data
Journal Articles

Cutting Edge: CD36 Mediates Phagocyte Tropism and Avirulence of Toxoplasma gondii

Yanlin Zhao, Jojo Reyes, Eliezer Rovira-Diaz, Barbara A. Fox, David J. Bzik, George S. Yap
Journal: The Journal of Immunology
J Immunol (2021) 207 (6): 1507–1512.
https://doi.org/10.4049/jimmunol.2100605
Published: 15 September 2021
View article titled, Cutting Edge: CD36 Mediates Phagocyte Tropism and Avirulence of <em>Toxoplasma gondii</em>
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Includes: Supplementary data
Journal Articles

Intrinsic Impairment of CD8 T Cells Induced by Helminth Coinfection

Eliezer Rovira, Darine W. El-Naccache, Yanlin Zhao, William Gause, George S Yap
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 156.8.
https://doi.org/10.4049/jimmunol.204.Supp.156.8
Published: 01 May 2020
View article titled, Intrinsic Impairment of CD8 T Cells Induced by Helminth Coinfection
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Journal Articles

IFN-γ control of metabolic stress response during T. gondii infection

JS B Reyes, Yanlin Zhao, George S Yap
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 80.12.
https://doi.org/10.4049/jimmunol.204.Supp.80.12
Published: 01 May 2020
View article titled, IFN-γ control of metabolic stress response during <em>T. gondii</em> infection
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Journal Articles

Toxoplasma gondii Inactivates Human Plasmacytoid Dendritic Cells by Functional Mimicry of IL-10

Piotr L. Pierog, Yanlin Zhao, Sukhwinder Singh, Jihong Dai, George S. Yap, Patricia Fitzgerald-Bocarsly
Journal: The Journal of Immunology
J Immunol (2018) 200 (1): 186–195.
https://doi.org/10.4049/jimmunol.1701045
Published: 01 January 2018
View article titled, <em>Toxoplasma gondii</em> Inactivates Human Plasmacytoid Dendritic Cells by Functional Mimicry of IL-10
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Journal Articles

Correction: Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10–Mediated Responses

Andrew Marple, Wenhui Wu, Suhagi Shah, Yanlin Zhao, Peicheng Du, William C. Gause, George S. Yap
Journal: The Journal of Immunology
J Immunol (2017) 199 (8): 3005.
https://doi.org/10.4049/jimmunol.1701193
Published: 15 October 2017
View article titled, Correction: Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10–Mediated Responses
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Journal Articles

Paneth Cell Specific Lysozyme Regulates Intestinal Mucosal Immune Response by Shaping Gut Microbiota Landscape

Shiyan Yu, Veronique Douard, Karen L. Edelblum, Daniel Laubitz, Yanlin Zhao, Pawel R Kiela, George S Yap, Nan Gao
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 218.13.
https://doi.org/10.4049/jimmunol.198.Supp.218.13
Published: 01 May 2017
View article titled, Paneth Cell Specific Lysozyme Regulates Intestinal Mucosal Immune Response by Shaping Gut Microbiota Landscape
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Journal Articles

Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10–Mediated Responses

Andrew Marple, Wenhui Wu, Suhagi Shah, Yanlin Zhao, Peicheng Du, William C. Gause, George S. Yap
Journal: The Journal of Immunology
J Immunol (2017) 198 (2): 634–639.
https://doi.org/10.4049/jimmunol.1601741
Published: 15 January 2017
View article titled, Cutting Edge: Helminth Coinfection Blocks Effector Differentiation of CD8 T Cells through Alternate Host Th2- and IL-10–Mediated Responses
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Includes: Supplementary data
Journal Articles

β-Catenin Signaling Drives Differentiation and Proinflammatory Function of IRF8-Dependent Dendritic Cells

Sara B. Cohen, Norah L. Smith, Courtney McDougal, Marion Pepper, Suhagi Shah, George S. Yap, Hans Acha-Orbea, Aimin Jiang, Björn E. Clausen, Brian D. Rudd, Eric Y. Denkers
Journal: The Journal of Immunology
J Immunol (2015) 194 (1): 210–222.
https://doi.org/10.4049/jimmunol.1402453
Published: 01 January 2015
View article titled, β-Catenin Signaling Drives Differentiation and Proinflammatory Function of IRF8-Dependent Dendritic Cells
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Includes: Supplementary data
Journal Articles

Virulent Toxoplasma gondii Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages

Yanlin Zhao, David J. P. Ferguson, Douglas C. Wilson, Jonathan C. Howard, L. David Sibley, George S. Yap
Journal: The Journal of Immunology
J Immunol (2009) 182 (6): 3775–3781.
https://doi.org/10.4049/jimmunol.0804190
Published: 15 March 2009
View article titled, Virulent <em>Toxoplasma gondii</em> Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages
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Journal Articles

IL-12 Signaling Drives CD8+ T Cell IFN-γ Production and Differentiation of KLRG1+ Effector Subpopulations during Toxoplasma gondii Infection

Douglas C. Wilson, Suzanne Matthews, George S. Yap
Journal: The Journal of Immunology
J Immunol (2008) 180 (9): 5935–5945.
https://doi.org/10.4049/jimmunol.180.9.5935
Published: 01 May 2008
View article titled, IL-12 Signaling Drives CD8<sup>+</sup> T Cell IFN-γ Production and Differentiation of KLRG1<sup>+</sup> Effector Subpopulations during <em>Toxoplasma gondii</em> Infection
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Journal Articles

Tyk2 Negatively Regulates Adaptive Th1 Immunity by Mediating IL-10 Signaling and Promoting IFN-γ-Dependent IL-10 Reactivation

Michael H. Shaw, Gordon J. Freeman, Mark F. Scott, Barbara A. Fox, David J. Bzik, Yasmine Belkaid, George S. Yap
Journal: The Journal of Immunology
J Immunol (2006) 176 (12): 7263–7271.
https://doi.org/10.4049/jimmunol.176.12.7263
Published: 15 June 2006
View article titled, Tyk2 Negatively Regulates Adaptive Th1 Immunity by Mediating IL-10 Signaling and Promoting IFN-γ-Dependent IL-10 Reactivation
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Journal Articles

Maintenance of Pulmonary Th1 Effector Function in Chronic Tuberculosis Requires Persistent IL-12 Production

Carl G. Feng, Dragana Jankovic, Marika Kullberg, Allen Cheever, Charles A. Scanga, Sara Hieny, Patricia Caspar, George S. Yap, Alan Sher
Journal: The Journal of Immunology
J Immunol (2005) 174 (7): 4185–4192.
https://doi.org/10.4049/jimmunol.174.7.4185
Published: 01 April 2005
View article titled, Maintenance of Pulmonary Th1 Effector Function in Chronic Tuberculosis Requires Persistent IL-12 Production
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Journal Articles

A Heritable Defect in IL-12 Signaling in B10.Q/J Mice. II. Effect on Acute Resistance to Toxoplasma gondii and Rescue by IL-18 Treatment

George S. Yap, Robert Ortmann, Ethan Shevach, Alan Sher
Journal: The Journal of Immunology
J Immunol (2001) 166 (9): 5720–5725.
https://doi.org/10.4049/jimmunol.166.9.5720
Published: 01 May 2001
View article titled, A Heritable Defect in IL-12 Signaling in B10.Q/J Mice. II. Effect on Acute Resistance to <em>Toxoplasma gondii</em> and Rescue by IL-18 Treatment
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Journal Articles

Recombinant Attenuated Toxoplasma gondii Expressing the Plasmodium yoelii Circumsporozoite Protein Provides Highly Effective Priming for CD8+ T Cell-Dependent Protective Immunity Against Malaria

Hugues Charest, Martha Sedegah, George S. Yap, Ricardo T. Gazzinelli, Patricia Caspar, Stephen L. Hoffman, Alan Sher
Journal: The Journal of Immunology
J Immunol (2000) 165 (4): 2084–2092.
https://doi.org/10.4049/jimmunol.165.4.2084
Published: 15 August 2000
View article titled, Recombinant Attenuated <em>Toxoplasma gondii</em> Expressing the <em>Plasmodium yoelii</em> Circumsporozoite Protein Provides Highly Effective Priming for CD8<sup>+</sup> T Cell-Dependent Protective Immunity Against Malaria
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Journal Articles

Decreased Resistance of TNF Receptor p55- and p75-Deficient Mice to Chronic Toxoplasmosis Despite Normal Activation of Inducible Nitric Oxide Synthase In Vivo

George S. Yap, Tanya Scharton-Kersten, Hugues Charest, Alan Sher
Journal: The Journal of Immunology
J Immunol (1998) 160 (3): 1340–1345.
https://doi.org/10.4049/jimmunol.160.3.1340
Published: 01 February 1998
View article titled, Decreased Resistance of TNF Receptor p55- and p75-Deficient Mice to Chronic Toxoplasmosis Despite Normal Activation of Inducible Nitric Oxide Synthase In Vivo
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