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Georges Leclercq
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Journal Articles

Regulatory Role for NK Cells in a Mouse Model of Systemic Juvenile Idiopathic Arthritis

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Jessica Vandenhaute, Anneleen Avau, Jessica Filtjens, Bert Malengier-Devlies, Maya Imbrechts, Nathalie Van den Berghe, Kourosh Ahmadzadeh, Tania Mitera, Louis Boon, Georges Leclercq, Carine Wouters, Patrick Matthys
Journal: The Journal of Immunology
J Immunol (2019) 203 (12): 3339–3348.
https://doi.org/10.4049/jimmunol.1900510
Published: 15 December 2019
View articletitled, Regulatory Role for NK Cells in a Mouse Model of Systemic Juvenile Idiopathic Arthritis
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Includes: Supplementary data
Journal Articles

Notch3 Activation Is Sufficient but Not Required for Inducing Human T-Lineage Specification

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Els Waegemans, Inge Van de Walle, Jelle De Medts, Magda De Smedt, Tessa Kerre, Bart Vandekerckhove, Georges Leclercq, Tao Wang, Jean Plum, Tom Taghon
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 5997–6004.
https://doi.org/10.4049/jimmunol.1400764
Published: 15 December 2014
View articletitled, Notch3 Activation Is Sufficient but Not Required for Inducing Human T-Lineage Specification
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Journal Articles

Education of Murine NK Cells Requires Both cis and trans Recognition of MHC Class I Molecules

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Stéphanie Bessoles, Georgi S. Angelov, Jonathan Back, Georges Leclercq, Eric Vivier, Werner Held
Journal: The Journal of Immunology
J Immunol (2013) 191 (10): 5044–5051.
https://doi.org/10.4049/jimmunol.1301971
Published: 15 November 2013
View articletitled, Education of Murine NK Cells Requires Both cis and trans Recognition of MHC Class I Molecules
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Includes: Supplementary data
Journal Articles

Differential Ly49e Expression Pathways in Resting versus TCR-Activated Intraepithelial γδ T Cells

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Tina Van Den Broeck, Els Van Ammel, Maarten Delforche, Sylvie Taveirne, Tessa Kerre, Bart Vandekerckhove, Tom Taghon, Jean Plum, Georges Leclercq
Journal: The Journal of Immunology
J Immunol (2013) 190 (5): 1982–1990.
https://doi.org/10.4049/jimmunol.1200354
Published: 01 March 2013
View articletitled, Differential Ly49e Expression Pathways in Resting versus TCR-Activated Intraepithelial γδ T Cells
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Journal Articles

Notch ligands control the human αβ/γδ lineage choice through receptor-specific induction of differential Notch signal strength. (111.29)

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Tom Taghon, Inge Van de Walle, Els Waegemans, Jelle De Medts, Greet De Smet, Magda De Smedt, Bart Vandekerckhove, Tessa Kerre, Georges Leclercq, Tao Wang, Jean Plum
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 111.29.
https://doi.org/10.4049/jimmunol.188.Supp.111.29
Published: 01 May 2012
View articletitled, Notch ligands control the human αβ/γδ lineage choice through receptor-specific induction of differential Notch signal strength. (111.29)
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Journal Articles

Functionally Mature CD4 and CD8 TCRαβ Cells Are Generated in OP9-DL1 Cultures from Human CD34+ Hematopoietic Cells

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Stefanie Van Coppernolle, Greet Verstichel, Frank Timmermans, Imke Velghe, David Vermijlen, Magda De Smedt, Georges Leclercq, Jean Plum, Tom Taghon, Bart Vandekerckhove, Tessa Kerre
Journal: The Journal of Immunology
J Immunol (2009) 183 (8): 4859–4870.
https://doi.org/10.4049/jimmunol.0900714
Published: 15 October 2009
View articletitled, Functionally Mature CD4 and CD8 TCRαβ Cells Are Generated in OP9-DL1 Cultures from Human CD34+ Hematopoietic Cells
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Includes: Supplementary data
Journal Articles

Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones

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Frank Timmermans, Imke Velghe, Lieve Vanwalleghem, Magda De Smedt, Stefanie Van Coppernolle, Tom Taghon, Harry D. Moore, Georges Leclercq, Anton W. Langerak, Tessa Kerre, Jean Plum, Bart Vandekerckhove
Journal: The Journal of Immunology
J Immunol (2009) 182 (11): 6879–6888.
https://doi.org/10.4049/jimmunol.0803670
Published: 01 June 2009
View articletitled, Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones
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Includes: Supplementary data
Journal Articles

CD27 Defines Phenotypically and Functionally Different Human NK Cell Subsets

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Mireille T. M. Vossen, Mourad Matmati, Kirsten M. L. Hertoghs, Paul A. Baars, Mi-Ran Gent, Georges Leclercq, Jörg Hamann, Taco W. Kuijpers, René A. W. van Lier
Journal: The Journal of Immunology
J Immunol (2008) 180 (6): 3739–3745.
https://doi.org/10.4049/jimmunol.180.6.3739
Published: 15 March 2008
View articletitled, CD27 Defines Phenotypically and Functionally Different Human NK Cell Subsets
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Journal Articles

Mouse TCRαβ+CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses

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Timothy L. Denning, Steve Granger, Daniel Mucida, Ryan Graddy, Georges Leclercq, Weiguo Zhang, Karen Honey, Jeffrey P. Rasmussen, Hilde Cheroutre, Alexander Y. Rudensky, Mitchell Kronenberg
Journal: The Journal of Immunology
J Immunol (2007) 178 (7): 4230–4239.
https://doi.org/10.4049/jimmunol.178.7.4230
Published: 01 April 2007
View articletitled, Mouse TCRαβ+CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses
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Journal Articles

Interactions of Ly49 Family Receptors with MHC Class I Ligands in trans and cis

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Léonardo Scarpellino, Franziska Oeschger, Philippe Guillaume, Jérôme D. Coudert, Frédéric Lévy, Georges Leclercq, Werner Held
Journal: The Journal of Immunology
J Immunol (2007) 178 (3): 1277–1284.
https://doi.org/10.4049/jimmunol.178.3.1277
Published: 01 February 2007
View articletitled, Interactions of Ly49 Family Receptors with MHC Class I Ligands in trans and cis
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Journal Articles

Active Form of Notch Imposes T Cell Fate in Human Progenitor Cells

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Magda De Smedt, Katia Reynvoet, Tessa Kerre, Tom Taghon, Bruno Verhasselt, Bart Vandekerckhove, Georges Leclercq, Jean Plum
Journal: The Journal of Immunology
J Immunol (2002) 169 (6): 3021–3029.
https://doi.org/10.4049/jimmunol.169.6.3021
Published: 15 September 2002
View articletitled, Active Form of Notch Imposes T Cell Fate in Human Progenitor Cells
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Journal Articles

Developmental and Functional Defects of Thymic and Epidermal Vγ3 Cells in IL-15-Deficient and IFN Regulatory Factor-1-Deficient Mice

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An De Creus, Katrien Van Beneden, Frederik Stevenaert, Veronique Debacker, Jean Plum, Georges Leclercq
Journal: The Journal of Immunology
J Immunol (2002) 168 (12): 6486–6493.
https://doi.org/10.4049/jimmunol.168.12.6486
Published: 15 June 2002
View articletitled, Developmental and Functional Defects of Thymic and Epidermal Vγ3 Cells in IL-15-Deficient and IFN Regulatory Factor-1-Deficient Mice
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Journal Articles

Expression of Inhibitory Receptors Ly49E and CD94/NKG2 on Fetal Thymic and Adult Epidermal TCR Vγ3 Lymphocytes

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Katrien Van Beneden, An De Creus, Frederik Stevenaert, Veronique Debacker, Jean Plum, Georges Leclercq
Journal: The Journal of Immunology
J Immunol (2002) 168 (7): 3295–3302.
https://doi.org/10.4049/jimmunol.168.7.3295
Published: 01 April 2002
View articletitled, Expression of Inhibitory Receptors Ly49E and CD94/NKG2 on Fetal Thymic and Adult Epidermal TCR Vγ3 Lymphocytes
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Journal Articles

Enforced Expression of GATA-3 Severely Reduces Human Thymic Cellularity

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Tom Taghon, Magda De Smedt, Frank Stolz, Maggy Cnockaert, Jean Plum, Georges Leclercq
Journal: The Journal of Immunology
J Immunol (2001) 167 (8): 4468–4475.
https://doi.org/10.4049/jimmunol.167.8.4468
Published: 15 October 2001
View articletitled, Enforced Expression of GATA-3 Severely Reduces Human Thymic Cellularity
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Journal Articles

Expression of Ly49E and CD94/NKG2 on Fetal and Adult NK Cells

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Katrien Van Beneden, Frederik Stevenaert, An De Creus, Veronique Debacker, Jozef De Boever, Jean Plum, Georges Leclercq
Journal: The Journal of Immunology
J Immunol (2001) 166 (7): 4302–4311.
https://doi.org/10.4049/jimmunol.166.7.4302
Published: 01 April 2001
View articletitled, Expression of Ly49E and CD94/NKG2 on Fetal and Adult NK Cells
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Journal Articles

Human B Cell Growth and Differentiation in the Spleen of Immunodeficient Mice

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Stany Depraetere, Lieven Verhoye, Georges Leclercq, Geert Leroux-Roels
Journal: The Journal of Immunology
J Immunol (2001) 166 (5): 2929–2936.
https://doi.org/10.4049/jimmunol.166.5.2929
Published: 01 March 2001
View articletitled, Human B Cell Growth and Differentiation in the Spleen of Immunodeficient Mice
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Journal Articles

Langerhans Cells That Have Matured In Vivo in the Absence of T Cells Are Fully Capable of Inducing a Helper CD4 as Well as a Cytotoxic CD8 Response

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An De Creus, Katrien Van Beneden, Tom Taghon, Frank Stolz, Veronique Debacker, Jean Plum, Georges Leclercq
Journal: The Journal of Immunology
J Immunol (2000) 165 (2): 645–653.
https://doi.org/10.4049/jimmunol.165.2.645
Published: 15 July 2000
View articletitled, Langerhans Cells That Have Matured In Vivo in the Absence of T Cells Are Fully Capable of Inducing a Helper CD4 as Well as a Cytotoxic CD8 Response
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Journal Articles

Signals from the IL-9 Receptor Are Critical for the Early Stages of Human Intrathymic T Cell Development

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Magda De Smedt, Bruno Verhasselt, Tessa Kerre, Dominique Vanhecke, Evelien Naessens, Georges Leclercq, Jean-Christophe Renauld, Jacques Van Snick, Jean Plum
Journal: The Journal of Immunology
J Immunol (2000) 164 (4): 1761–1767.
https://doi.org/10.4049/jimmunol.164.4.1761
Published: 15 February 2000
View articletitled, Signals from the IL-9 Receptor Are Critical for the Early Stages of Human Intrathymic T Cell Development
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Journal Articles

In Vitro Intrathymic Differentiation Kinetics of Human Fetal Liver CD34+CD38− Progenitors Reveals a Phenotypically Defined Dendritic/T-NK Precursor Split

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Jean Plum, Magda De Smedt, Bruno Verhasselt, Fritz Offner, Tessa Kerre, Dominique Vanhecke, Georges Leclercq, Bart Vandekerckhove
Journal: The Journal of Immunology
J Immunol (1999) 162 (1): 60–68.
https://doi.org/10.4049/jimmunol.162.1.60
Published: 01 January 1999
View articletitled, In Vitro Intrathymic Differentiation Kinetics of Human Fetal Liver CD34+CD38− Progenitors Reveals a Phenotypically Defined Dendritic/T-NK Precursor Split
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