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Gisa Tiegs
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Journal Articles

A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury

Dörte Kleinschmidt, Anastasios D. Giannou, Heather M. McGee, Jan Kempski, Babett Steglich, Francis Jessica Huber, Thomas Michael Ernst, Ahmad Mustafa Shiri, Claudia Wegscheid, Elena Tasika, Peter Hübener, Philipp Huber, Tanja Bedke, Niklas Steffens, Theodora Agalioti, Tobias Fuchs, Jill Noll, Hannelore Lotter, Gisa Tiegs, Ansgar W. Lohse, Jonathan H. Axelrod, Eithan Galun, Richard A. Flavell, Nicola Gagliani, Samuel Huber
Journal: The Journal of Immunology
J Immunol (2017) 199 (12): 4078–4090.
https://doi.org/10.4049/jimmunol.1700587
Published: 15 December 2017
View article titled, A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury
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Includes: Supplementary data
Journal Articles

A Proinflammatory Role of Type 2 Innate Lymphoid Cells in Murine Immune-Mediated Hepatitis

Katrin Neumann, Khalil Karimi, Jana Meiners, Ruth Voetlause, Silja Steinmann, Werner Dammermann, Stefan Lüth, Farahnaz Asghari, Claudia Wegscheid, Andrea K. Horst, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2017) 198 (1): 128–137.
https://doi.org/10.4049/jimmunol.1600418
Published: 01 January 2017
View article titled, A Proinflammatory Role of Type 2 Innate Lymphoid Cells in Murine Immune-Mediated Hepatitis
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Includes: Supplementary data
Journal Articles

Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis

Dorothee Schwinge, Antonella Carambia, Alexander Quaas, Till Krech, Claudia Wegscheid, Gisa Tiegs, Immo Prinz, Ansgar W. Lohse, Johannes Herkel, Christoph Schramm
Journal: The Journal of Immunology
J Immunol (2015) 194 (6): 2522–2530.
https://doi.org/10.4049/jimmunol.1400076
Published: 15 March 2015
View article titled, Testosterone Suppresses Hepatic Inflammation by the Downregulation of IL-17, CXCL-9, and CXCL-10 in a Mouse Model of Experimental Acute Cholangitis
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Includes: Supplementary data
Journal Articles

Hepatocytes Contribute to Immune Regulation in the Liver by Activation of the Notch Signaling Pathway in T Cells

Sven Burghardt, Annette Erhardt, Benjamin Claass, Samuel Huber, Guido Adler, Thomas Jacobs, Athena Chalaris, Dirk Schmidt-Arras, Stefan Rose-John, Khalil Karimi, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2013) 191 (11): 5574–5582.
https://doi.org/10.4049/jimmunol.1300826
Published: 01 December 2013
View article titled, Hepatocytes Contribute to Immune Regulation in the Liver by Activation of the Notch Signaling Pathway in T Cells
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Includes: Supplementary data
Journal Articles

CXCR3 Deficiency Exacerbates Liver Disease and Abrogates Tolerance in a Mouse Model of Immune-Mediated Hepatitis

Annette Erhardt, Claudia Wegscheid, Benjamin Claass, Antonella Carambia, Johannes Herkel, Hans-Willi Mittrücker, Ulf Panzer, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2011) 186 (9): 5284–5293.
https://doi.org/10.4049/jimmunol.1003750
Published: 01 May 2011
View article titled, CXCR3 Deficiency Exacerbates Liver Disease and Abrogates Tolerance in a Mouse Model of Immune-Mediated Hepatitis
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Journal Articles

TNF Pretreatment Interferes with Mitochondrial Apoptosis in the Mouse Liver by A20-Mediated Down-Regulation of Bax

Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2007) 179 (10): 7042–7049.
https://doi.org/10.4049/jimmunol.179.10.7042
Published: 15 November 2007
View article titled, TNF Pretreatment Interferes with Mitochondrial Apoptosis in the Mouse Liver by A20-Mediated Down-Regulation of Bax
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Journal Articles

Kupffer Cell-Expressed Membrane-Bound TNF Mediates Melphalan Hepatotoxicity via Activation of Both TNF Receptors

Matthias Kresse, Markus Latta, Gerald Künstle, Hans-Martin Riehle, Nico van Rooijen, Hannes Hentze, Gisa Tiegs, Markus Biburger, Rudolf Lucas, Albrecht Wendel
Journal: The Journal of Immunology
J Immunol (2005) 175 (6): 4076–4083.
https://doi.org/10.4049/jimmunol.175.6.4076
Published: 15 September 2005
View article titled, Kupffer Cell-Expressed Membrane-Bound TNF Mediates Melphalan Hepatotoxicity via Activation of Both TNF Receptors
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Journal Articles

α-Galactosylceramide-Induced Liver Injury in Mice Is Mediated by TNF-α but Independent of Kupffer Cells

Markus Biburger, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2005) 175 (3): 1540–1550.
https://doi.org/10.4049/jimmunol.175.3.1540
Published: 01 August 2005
View article titled, α-Galactosylceramide-Induced Liver Injury in Mice Is Mediated by TNF-α but Independent of Kupffer Cells
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Journal Articles

NK Cells, but Not NKT Cells, Are Involved in Pseudomonas aeruginosa Exotoxin A-Induced Hepatotoxicity in Mice

Katrin A. Mühlen, Jens Schümann, Frederick Wittke, Steffen Stenger, Nico van Rooijen, Luc van Kaer, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2004) 172 (5): 3034–3041.
https://doi.org/10.4049/jimmunol.172.5.3034
Published: 01 March 2004
View article titled, NK Cells, but Not NKT Cells, Are Involved in <em>Pseudomonas aeruginosa</em> Exotoxin A-Induced Hepatotoxicity in Mice
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Journal Articles

Parenchymal, But Not Leukocyte, TNF Receptor 2 Mediates T Cell-Dependent Hepatitis in Mice

Jens Schümann, Katrin Mühlen, Alexandra K. Kiemer, Angelika M. Vollmar, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2003) 170 (4): 2129–2137.
https://doi.org/10.4049/jimmunol.170.4.2129
Published: 15 February 2003
View article titled, Parenchymal, But Not Leukocyte, TNF Receptor 2 Mediates T Cell-Dependent Hepatitis in Mice
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Journal Articles

Chronic Inflammation and Protection from Acute Hepatitis in Transgenic Mice Expressing TNF in Endothelial Cells

Antje Willuweit, Gabriele Sass, Annette Schöneberg, Ulrich Eisel, Gisa Tiegs, Matthias Clauss
Journal: The Journal of Immunology
J Immunol (2001) 167 (7): 3944–3952.
https://doi.org/10.4049/jimmunol.167.7.3944
Published: 01 October 2001
View article titled, Chronic Inflammation and Protection from Acute Hepatitis in Transgenic Mice Expressing TNF in Endothelial Cells
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Journal Articles

Dissection of the Intracellular Pathways in Hepatocytes Suggests a Role for Jun Kinase and IFN Regulatory Factor-1 in Con A-Induced Liver Failure

Konrad Streetz, Bastian Fregien, Jörg Plümpe, Kerstin Körber, Stefan Kubicka, G. Sass, Stephan C. Bischoff, Michael P. Manns, Gisa Tiegs, Christian Trautwein
Journal: The Journal of Immunology
J Immunol (2001) 167 (1): 514–523.
https://doi.org/10.4049/jimmunol.167.1.514
Published: 01 July 2001
View article titled, Dissection of the Intracellular Pathways in Hepatocytes Suggests a Role for Jun Kinase and IFN Regulatory Factor-1 in Con A-Induced Liver Failure
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Journal Articles

TNF-α-Induced Expression of Adhesion Molecules in the Liver Is Under the Control of TNFR1—Relevance for Concanavalin A-Induced Hepatitis

Dominik Wolf, Rupert Hallmann, Gabriele Sass, Michael Sixt, Sabine Küsters, Bastian Fregien, Christian Trautwein, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (2001) 166 (2): 1300–1307.
https://doi.org/10.4049/jimmunol.166.2.1300
Published: 15 January 2001
View article titled, TNF-α-Induced Expression of Adhesion Molecules in the Liver Is Under the Control of TNFR1—Relevance for Concanavalin A-Induced Hepatitis
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Journal Articles

Acute Hepatotoxicity of Pseudomonas aeruginosa Exotoxin A in Mice Depends on T Cells and TNF

Jens Schümann, Sabine Angermüller, Renate Bang, Michael Lohoff, Gisa Tiegs
Journal: The Journal of Immunology
J Immunol (1998) 161 (10): 5745–5754.
https://doi.org/10.4049/jimmunol.161.10.5745
Published: 15 November 1998
View article titled, Acute Hepatotoxicity of <em>Pseudomonas aeruginosa</em> Exotoxin A in Mice Depends on T Cells and TNF
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