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Journal Articles

Correction: Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses

Wenjing Li, Lei Shi, Zhenpeng Zhuang, Han Wu, Meng Lian, Yihui Chen, Lei Li, Weikai Ge, Qin Jin, Quanjun Zhang, Yu Zhao, Zhaoming Liu, Zhen Ouyang, Yinghua Ye, Yingying Li, Hai Wang, Yuan Liao, Longquan Quan, Lei Xiao, Liangxue Lai, Guangxun Meng, Kepin Wang
Journal: The Journal of Immunology
J Immunol (2021) 207 (9): 2385–2386.
https://doi.org/10.4049/jimmunol.2100753
Published: 01 November 2021
View articletitled, Correction: Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses
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Journal Articles

Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses

Wenjing Li, Lei Shi, Zhenpeng Zhuang, Han Wu, Meng Lian, Yihui Chen, Lei Li, Weikai Ge, Qin Jin, Quanjun Zhang, Yu Zhao, Zhaoming Liu, Zhen Ouyang, Yinghua Ye, Yingying Li, Hai Wang, Yuan Liao, Longquan Quan, Lei Xiao, Liangxue Lai, Guangxun Meng, Kepin Wang
Journal: The Journal of Immunology
J Immunol (2020) 205 (9): 2532–2544.
https://doi.org/10.4049/jimmunol.1901468
Published: 01 November 2020
View articletitled, Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses
Open the PDF for Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses in another window
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Includes: Supplementary data
Journal Articles

Autoinflammatory Eye Disease Due to NLRP3 Inflammasome-Associated Mutations and Excessive IL-1β Responses may be Driven by Ocular Exposure to Commensals

Jay Siak, Anthony J St. Leger, Mary Mattapallil, M. Teresa Magone, Wadih Zein, Sara Alehashemi, Kumarkrishna Raychaudhuri, Guangxun Meng, Ivan Fuss, Warren Strober, Raphaela Goldbach-Mansky, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 224.41.
https://doi.org/10.4049/jimmunol.204.Supp.224.41
Published: 01 May 2020
View articletitled, Autoinflammatory Eye Disease Due to NLRP3 Inflammasome-Associated Mutations and Excessive IL-1β Responses may be Driven by Ocular Exposure to Commensals
Add to Citation Manager for Autoinflammatory Eye Disease Due to NLRP3 Inflammasome-Associated Mutations and Excessive IL-1β Responses may be Driven by Ocular Exposure to Commensals
Journal Articles

AIM2 deficient mice develop severe Systemic Lupus Erythematosus pathogenesis due to elevated type I interferon signaling

Guangxun Meng, Ailing LU, Shuxian WU
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 219.15.
https://doi.org/10.4049/jimmunol.204.Supp.219.15
Published: 01 May 2020
View articletitled, AIM2 deficient mice develop severe Systemic Lupus Erythematosus pathogenesis due to elevated type I interferon signaling
Add to Citation Manager for AIM2 deficient mice develop severe Systemic Lupus Erythematosus pathogenesis due to elevated type I interferon signaling
Journal Articles

Correction: β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

Kairui Mao, Shuzhen Chen, Yan Wang, Yan Zeng, Yonglei Ma, Yu Hu, Hong Zhang, Shuhui Sun, Xiaodong Wu, Guangxun Meng, Gang Pei, Bing Sun
Journal: The Journal of Immunology
J Immunol (2020) 204 (5): 1410.
https://doi.org/10.4049/jimmunol.1901500
Published: 01 March 2020
View articletitled, Correction: β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes
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Journal Articles

Correction: Deficiency of the AIM2–ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection

Shanshan Yan, Hongbo Shen, Qiaoshi Lian, Wenlong Jin, Ronghua Zhang, Xuan Lin, Wangpeng Gu, Xiaoyu Sun, Guangxun Meng, Zhigang Tian, Zheng W. Chen, Bing Sun
Journal: The Journal of Immunology
J Immunol (2020) 204 (2): 472.
https://doi.org/10.4049/jimmunol.1901370
Published: 15 January 2020
View articletitled, Correction: Deficiency of the AIM2–ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection
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Journal Articles

Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist

Yihui Chen, Hongbin Wang, Junchen Shen, Rong Deng, Xiaomin Yao, Qiuhong Guo, Ailing Lu, Bing Sun, Yan Zhang, Guangxun Meng
Journal: The Journal of Immunology
J Immunol (2019) 203 (10): 2712–2723.
https://doi.org/10.4049/jimmunol.1900212
Published: 15 November 2019
View articletitled, Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist
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Add to Citation Manager for Gasdermin D Drives the Nonexosomal Secretion of Galectin-3, an Insulin Signal Antagonist
Includes: Supplementary data
Journal Articles

Intestinal Epithelial Cell–Derived LKB1 Suppresses Colitogenic Microbiota

Xia’nan Liu, Jinfeng Lu, Zhenshan Liu, Junjie Zhao, Hongxiang Sun, Ningbo Wu, Hongzhi Liu, Weiwei Liu, Zhuqin Hu, Guangxun Meng, Lei Shen, Aaron W. Miller, Bing Su, Xiaoxia Li, Zizhen Kang
Journal: The Journal of Immunology
J Immunol (2018) 200 (5): 1889–1900.
https://doi.org/10.4049/jimmunol.1700547
Published: 01 March 2018
View articletitled, Intestinal Epithelial Cell–Derived LKB1 Suppresses Colitogenic Microbiota
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Includes: Supplementary data
Journal Articles

Deficiency of the AIM2–ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection

Shanshan Yan, Hongbo Shen, Qiaoshi Lian, Wenlong Jin, Ronghua Zhang, Xuan Lin, Wangpeng Gu, Xiaoyu Sun, Guangxun Meng, Zhigang Tian, Zheng W. Chen, Bing Sun
Journal: The Journal of Immunology
J Immunol (2018) 200 (3): 1016–1026.
https://doi.org/10.4049/jimmunol.1701177
Published: 01 February 2018
View articletitled, Deficiency of the AIM2–ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection
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Includes: Supplementary data
Journal Articles

Cutting Edge: TRAF6 Mediates TLR/IL-1R Signaling–Induced Nontranscriptional Priming of the NLRP3 Inflammasome

Yue Xing, Xiaomin Yao, Hua Li, Guang Xue, Qiuhong Guo, Guiwen Yang, Liguo An, Yan Zhang, Guangxun Meng
Journal: The Journal of Immunology
J Immunol (2017) 199 (5): 1561–1566.
https://doi.org/10.4049/jimmunol.1700175
Published: 01 September 2017
View articletitled, Cutting Edge: TRAF6 Mediates TLR/IL-1R Signaling–Induced Nontranscriptional Priming of the NLRP3 Inflammasome
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Includes: Supplementary data
Journal Articles

Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus

Ailing Lu, Hua Li, Junling Niu, Shuxian Wu, Guang Xue, Xiaomin Yao, Qiuhong Guo, Nianhong Wan, Paride Abliz, Guiwen Yang, Liguo An, Guangxun Meng
Journal: The Journal of Immunology
J Immunol (2017) 198 (3): 1119–1129.
https://doi.org/10.4049/jimmunol.1600659
Published: 01 February 2017
View articletitled, Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus
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Journal Articles

Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes

Mingkuan Chen, Yue Xing, Ailing Lu, Wei Fang, Bing Sun, Changbin Chen, Wanqing Liao, Guangxun Meng
Journal: The Journal of Immunology
J Immunol (2015) 195 (10): 4962–4972.
https://doi.org/10.4049/jimmunol.1500865
Published: 15 November 2015
View articletitled, Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes
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Includes: Supplementary data
Journal Articles

β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes

Kairui Mao, Shuzhen Chen, Yan Wang, Yan Zeng, Yonglei Ma, Yu Hu, Hong Zhang, Shuhui Sun, Xiaodong Wu, Guangxun Meng, Gang Pei, Bing Sun
Journal: The Journal of Immunology
J Immunol (2015) 194 (4): 1867–1873.
https://doi.org/10.4049/jimmunol.1401989
Published: 15 February 2015
View articletitled, β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes
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Includes: Supplementary data
Journal Articles

Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production

Yu Hu, Kairui Mao, Yan Zeng, Shuzhen Chen, Zhiyun Tao, Chen Yang, Shuhui Sun, Xiaodong Wu, Guangxun Meng, Bing Sun
Journal: The Journal of Immunology
J Immunol (2010) 185 (12): 7699–7705.
https://doi.org/10.4049/jimmunol.1001099
Published: 15 December 2010
View articletitled, Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production
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Add to Citation Manager for Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production
Includes: Supplementary data