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Gunilla B. Karlsson Hedestam
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Journal Articles

Polyfunctional Tier 2–Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor

David A. Spencer, Delphine C. Malherbe, Néstor Vázquez Bernat, Monika Ádori, Benjamin Goldberg, Nicholas Dambrauskas, Heidi Henderson, Shilpi Pandey, Tracy Cheever, Philip Barnette, William F. Sutton, Margaret E. Ackerman, James J. Kobie, D. Noah Sather, Gunilla B. Karlsson Hedestam, Nancy L. Haigwood, Ann J. Hessell
Journal: The Journal of Immunology
J Immunol (2021) 206 (5): 999–1012.
DOI: https://doi.org/10.4049/jimmunol.2001082
Published: 01 March 2021
View article titled, Polyfunctional Tier 2–Neutralizing Antibodies Cloned following HIV-1 Env Macaque Immunization Mirror Native Antibodies in a Human Donor
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Includes: Supplementary data
Journal Articles

Characterization of heterologous HIV-1 Tier 2 neutralizing mAbs cloned from a macaque immunized with viral quasispecies present in a human subject with neutralization breadth

David A Spencer, Delphine C Malherbe, Heidi Henderson, Shilpi Pandy, Néstor Vázquez Bernat, Monika Àdori, Ben Goldberg, Nicholas Dambrauskas, William Sutton, Noah Sather, James Kobie, Margaret E Ackerman, Gunilla B Karlsson Hedestam, Nancy Logan Haigwood, Ann Jones Hessell
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 72.9.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.72.9
Published: 01 May 2019
View article titled, Characterization of heterologous HIV-1 Tier 2 neutralizing mAbs cloned from a macaque immunized with viral quasispecies present in a human subject with neutralization breadth
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Journal Articles

Altered Marginal Zone B Cell Selection in the Absence of IκBNS

Monika Ádori, Gabriel K. Pedersen, Csaba Ádori, Elina Erikson, Sharesta Khoenkhoen, Julian M. Stark, Jin Huk Choi, Pia Dosenovic, Mikael C. I. Karlsson, Bruce Beutler, Gunilla B. Karlsson Hedestam
Journal: The Journal of Immunology
J Immunol (2018) 200 (2): 775–787.
DOI: https://doi.org/10.4049/jimmunol.1700791
Published: 15 January 2018
View article titled, Altered Marginal Zone B Cell Selection in the Absence of IκBNS
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Includes: Supplementary data
Journal Articles

Effects of temporary BLyS treatment of rhesus macaques

Jean Scholz, Bapi Pahar, Joanna B Madej, Martina Soldemo, Wendy Lala Trunch, Javier Guenaga, Arpita Myles, Karen Tran, Richard T Wyatt, Gunilla B Karlsson Hedestam, Andrew Lackner, Michael Cancro
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 215.19.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.215.19
Published: 01 May 2017
View article titled, Effects of temporary BLyS treatment of rhesus macaques
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Journal Articles

High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

Yimeng Wang, Christopher Sundling, Richard Wilson, Sijy O’Dell, Yajing Chen, Kaifan Dai, Ganesh E. Phad, Jiang Zhu, Yongli Xiao, John R. Mascola, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, Yuxing Li
Journal: The Journal of Immunology
J Immunol (2016) 196 (9): 3729–3743.
DOI: https://doi.org/10.4049/jimmunol.1502543
Published: 01 May 2016
View article titled, High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence
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Includes: Supplementary data
Journal Articles

Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization

Ganesh E. Phad, Néstor Vázquez Bernat, Yu Feng, Jidnyasa Ingale, Paola Andrea Martinez Murillo, Sijy O’Dell, Yuxing Li, John R. Mascola, Christopher Sundling, Richard T. Wyatt, Gunilla B. Karlsson Hedestam
Journal: The Journal of Immunology
J Immunol (2015) 194 (12): 5903–5914.
DOI: https://doi.org/10.4049/jimmunol.1500122
Published: 15 June 2015
View article titled, Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization
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Includes: Supplementary data
Journal Articles

Protection of Human Myeloid Dendritic Cell Subsets against Influenza A Virus Infection Is Differentially Regulated upon TLR Stimulation

Faezzah Baharom, Saskia Thomas, Andrea Bieder, Maria Hellmér, Julia Volz, Kerrie J. Sandgren, Gerald M. McInerney, Gunilla B. Karlsson Hedestam, Ira Mellman, Anna Smed-Sörensen
Journal: The Journal of Immunology
J Immunol (2015) 194 (9): 4422–4430.
DOI: https://doi.org/10.4049/jimmunol.1402671
Published: 01 May 2015
View article titled, Protection of Human Myeloid Dendritic Cell Subsets against Influenza A Virus Infection Is Differentially Regulated upon TLR Stimulation
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Includes: Supplementary data
Journal Articles

Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

Christopher Sundling, Zhenhai Zhang, Ganesh E. Phad, Zizhang Sheng, Yimeng Wang, John R. Mascola, Yuxing Li, Richard T. Wyatt, Lawrence Shapiro, Gunilla B. Karlsson Hedestam
Journal: The Journal of Immunology
J Immunol (2014) 192 (8): 3637–3644.
DOI: https://doi.org/10.4049/jimmunol.1303334
Published: 15 April 2014
View article titled, Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization
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Includes: Supplementary data
Journal Articles

Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation

Kerrie J. Sandgren, Anna Smed-Sörensen, Mattias N. Forsell, Martina Soldemo, William C. Adams, Frank Liang, Leif Perbeck, Richard A. Koup, Richard T. Wyatt, Gunilla B. Karlsson Hedestam, Karin Loré
Journal: The Journal of Immunology
J Immunol (2013) 191 (1): 60–69.
DOI: https://doi.org/10.4049/jimmunol.1202489
Published: 01 July 2013
View article titled, Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation
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Includes: Supplementary data
Journal Articles

Independent Expansion of Epitope-Specific Plasma Cell Responses upon HIV-1 Envelope Glycoprotein Immunization

Mattias N. E. Forsell, Martina Soldemo, Pia Dosenovic, Richard T. Wyatt, Mikael C. I. Karlsson, Gunilla B. Karlsson Hedestam
Journal: The Journal of Immunology
J Immunol (2013) 191 (1): 44–51.
DOI: https://doi.org/10.4049/jimmunol.1203087
Published: 01 July 2013
View article titled, Independent Expansion of Epitope-Specific Plasma Cell Responses upon HIV-1 Envelope Glycoprotein Immunization
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Journal Articles

BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses

Pia Dosenovic, Martina Soldemo, Jean L. Scholz, Sijy O’Dell, Emilie K. Grasset, Nadège Pelletier, Mikael C. I. Karlsson, John R. Mascola, Richard T. Wyatt, Michael P. Cancro, Gunilla B. Karlsson Hedestam
Journal: The Journal of Immunology
J Immunol (2012) 188 (12): 6018–6026.
DOI: https://doi.org/10.4049/jimmunol.1200466
Published: 15 June 2012
View article titled, BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses
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Includes: Supplementary data
Journal Articles

Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization

Pia Dosenovic, Bimal Chakrabarti, Martina Soldemo, Iyadh Douagi, Mattias N. E. Forsell, Yuxing Li, Adhuna Phogat, Staffan Paulie, James Hoxie, Richard T. Wyatt, Gunilla B. Karlsson Hedestam
Journal: The Journal of Immunology
J Immunol (2009) 183 (5): 3373–3382.
DOI: https://doi.org/10.4049/jimmunol.0900407
Published: 01 September 2009
View article titled, Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization
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Includes: Supplementary data
Journal Articles

Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells

Iyadh Douagi, Cornelia Gujer, Christopher Sundling, William C. Adams, Anna Smed-Sörensen, Robert A. Seder, Gunilla B. Karlsson Hedestam, Karin Loré
Journal: The Journal of Immunology
J Immunol (2009) 182 (4): 1991–2001.
DOI: https://doi.org/10.4049/jimmunol.0802257
Published: 15 February 2009
View article titled, Human B Cell Responses to TLR Ligands Are Differentially Modulated by Myeloid and Plasmacytoid Dendritic Cells
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Includes: Supplementary data
Journal Articles

DAP12 Signaling Regulates Plasmacytoid Dendritic Cell Homeostasis and Down-Modulates Their Function during Viral Infection

Hanna Sjölin, Scott H. Robbins, Gilles Bessou, Åsa Hidmark, Elena Tomasello, Maria Johansson, Håkan Hall, Férose Charifi, Gunilla B. Karlsson Hedestam, Christine A. Biron, Klas Kärre, Petter Höglund, Eric Vivier, Marc Dalod
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 2908–2916.
DOI: https://doi.org/10.4049/jimmunol.177.5.2908
Published: 01 September 2006
View article titled, DAP12 Signaling Regulates Plasmacytoid Dendritic Cell Homeostasis and Down-Modulates Their Function during Viral Infection
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